Clinical trials: Variability
Critical Care, Weaning
Heart Rate Variability During Weaning From Mechanical Ventilation
The discontinuation of mechanical ventilation (MV) and the recovery of spontaneous breathing can lead to important cardiovascular alterations due to changes in the intrathoracic pressure.
- Trial name
- NCT00851825
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Stage I Lung Cancer, Stage I Non-Small Cell Lung Cancer AJCC v7
Fludeoxyglucose F-18-PET in Planning Lung Cancer Radiation Therapy
This trial studies how well fludeoxyglucose F-18 - positron emission tomography (PET) works in planning radiation therapy in participants with early non-small cell lung cancer, early stage lung cancer, or cancer that has spread…
- Conditions
- Stage I Lung Cancer, Stage I Non-Small Cell Lung Cancer AJCC v7, Stage IA Non-Small Cell Lung Carcinoma AJCC v7, Stage IB Non-Small Cell Lung Carcinoma AJCC v7
- Trial name
- NCT03493789
- Testing
- Fludeoxyglucose F-18, Positron Emission Tomography (PET), Stereotactic Body Radiation Therapy (SBRT)
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Emory University
Stress, Heart Rate Variability
Heart Rate Variability and Stress Management Enhancement
This study will be conducted by using two devices (Apollo and Biostrap) for monitoring of baseline physiologic variables and heart rate variability.
- Trial name
- NCT04381182
- Testing
- Apollo Wearable Device
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Joseph Maroon
Grief, Cardiovascular Health
Cardiovascular Effects of Grieving
Self-affirmation (SA) theory proposes that people are motivated to maintain a positive self-image of being worthy, stable, and capable.
- Conditions
- Grief, Cardiovascular Health, Emotion
- Trial name
- SAGE (NCT07356635)
- Testing
- Value-affirmation
- Where
- United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Sleep
Feasibility of a Bedtime Variability Protocol
The purpose of this study is to find out if parents and children 6-10 years old are willing and able to follow a protocol to be used to study the effects of short and/or variable sleep in children.
- Trial name
- NCT06501690
- Testing
- Late bedtime, Variable bedtime
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Penn State University
Anti-Psychotic, Management of Manifestations of Psychotic Disorders
Assessment of Intra-subject Variability in the Bioavailability of Chlorpromazine Hydrochloride
Cycle Pharmaceuticals Ltd. (Cycle) is developing an oral tablet formulation of Chlorpromazine Hydrochloride and intends to conduct bioequivalence trials to demonstrate its similarity to the RLD.
- Conditions
- Anti-Psychotic, Management of Manifestations of Psychotic Disorders, Treatment of Schizophrenia, Control Nausea and Vomiting
- Trial name
- NCT02943213
- Testing
- Chlorpromazine Hydrochloride
- Where
- South Africa
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cycle Pharmaceuticals Ltd.
Sedentary Behavior, Mild Cognitive Impairment
The DURATION Study: reDUcing sedentaRy behAviour to Maintain cogniTIve functiON.
Rationale: Older adults spend the majority of their time in sedentary behaviours (SB). High amounts of SB have been correlated with reduced cognitive performance.
- Conditions
- Sedentary Behavior, Mild Cognitive Impairment, Glucose Intolerance, Overweight and Obesity
- Trial name
- NCT04323423
- Testing
- interrupting sedentary behaviour with light physical activity
- Where
- Canada
- Sponsor
- Western University, Canada
Anesthesia, General, Fluid Therapy
Management of Intraoperative Fluids in Ambulatory Surgery
This is a single-center prospective randomized control trial (RCT) to determine whether the continuous monitoring of the plethysmographic variability index (PVI) during low-risk surgeries, can be used to optimize the…
- Conditions
- Anesthesia, General, Fluid Therapy, Ambulatory Surgical Procedures
- Trial name
- MIFAS (NCT03193320)
- Testing
- Fluid therapy protocol
- Where
- Venezuela
- Volunteers
- 243 people, healthy volunteers welcome
- Sponsor
- Policlinica Metropolitana
Atrial Septal Defect, Pulmonary Hypertension
Atrial Septal Defect - Exercise Capacity and Pulmonary Hypertension
The purpose of the study is to compare exercise capacity, cardiac contractility, pulmonary vascular pressures and heart rate variability between patients with an atrial septal defect and healthy controls.
- Trial name
- NCT03565471
- Testing
- Echocardiography, Right side catheterization, Exercise test
- Where
- Denmark
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Effects of; Serum, Urine Marking
Biological Variability in Cartilage Specific Biomarkers in Healthy Volunteers.
The purposes of the study are to assess intra individual biological variability of serum and urinary cartilage specific biomarkers and define the best standardized conditions for blood and urine sampling in the frame of…
- Trial name
- COVAR (NCT02348944)
- Testing
- serum and urine sample
- Where
- Belgium
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Artialis
Gonarthrosis, Knee Osteoarthritis
Efficacy of Craniosacral Therapy in Patients With Gonarthrosis
This randomized controlled trial was designed to investigate the effects of craniosacral therapy on pain, heart rate variability, joint stiffness, physical function, quality of life, body image, kinesiophobia, and dynamic balance…
- Trial name
- NCT07372534
- Testing
- Craniosacral Therapy, Home-Based Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 21 people
- Sponsor
- Ankara Yildirim Beyazıt University
Hyperglycemia, Insulin Sensitivity
Investigating Inter-individual Variability in Glycemic and Insulin Responses
This study aims to test the following hypothesis in healthy lean young men: There are differences in glycemic response (GR) and insulin response (IR) between Chinese, Malay and Asian-Indian There are differences in GI values to…
- Trial name
- NCT01804738
- Testing
- Jasmine rice, Parboiled basmati rice
- Where
- Singapore
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Institute for Human Development and Potential (IHDP), Singapore
Diabetes Mellitus, Type 2
DPP4 Inhibitor on Glycemic Variability
The investigators conducted a prospective study in patients with T2DM on twice daily MHI with or without metformin therapy. Blinded continuous glucose monitoring was performed at baseline and following 6 weeks of Vildagliptin…
- Trial name
- NCT04654676
- Testing
- Vildagliptin
- Where
- Malaysia
- Volunteers
- 12 people
- Sponsor
- University Malaysia Sarawak
Cryotherapy Effect
The Effects of Cold Water Immersion With Different Dosages (Duration and Temperature Variations) on Heart Rate Variability Post-exercise Recovery
The aim of the present study was to investigate the effects of cold water immersion (CWI) during post-exercise recovery with different durations and temperatures on heart rate variability (HRV) indices.
- Trial name
- NCT02499640
- Testing
- immersion cold water
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Paulista University
Parent-Child Relations, Preterm Birth
Bilateral Infant Stimulation Study
This study will investigate stress that parents of children admitted to the neonatal intensive care unit (NICU) experience. Investigation of a novel intervention of using bilateral alternating stimulation to reduce parental…
- Conditions
- Parent-Child Relations, Preterm Birth, Stress Reaction, Hospitalism in Children
- Trial name
- BLISS (NCT06353243)
- Testing
- Bilateral alternating stimulation
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Oregon Health and Science University
Cerebral Palsy (CP)
The Effect of Spinal Manipulation on Heart Rate Variability in Children With Cerebral Palsy.
This randomized, sham-controlled crossover trial aims to evaluate the immediate effects of spinal manipulation on heart rate variability in children with cerebral palsy.
- Trial name
- NCT07504640
- Testing
- Spinal manipulation
- Where
- Ukraine
- Volunteers
- 20 people
- Sponsor
- International Clinic of Rehabilitation, Ukraine
Healthy Subject, Heart Rate Variability
Osteopathic Manipulative Treatment Effects on High Frequency Parameters in Healthy Subjects
The aim of the present study is to determine the extend to which osteopathic manipulative treatment (OMT) is effective on a sample of healthy subjects in changing high frequency (HF) parameters.
- Trial name
- NCT01908920
- Testing
- Osteopathic manipulative treatment, CONTROL
- Where
- Italy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- European Institute for Evidence Based Osteopathic Medicine
Obesity
Evaluation of Heart Rate Variability and Endothelial Function Three Months After Bariatric Surgery
Was performed a longitudinal, study with twenty patients recruited for the bariatric surgery group and 20 for clinical treatment.
- Trial name
- NCT03911479
- Testing
- Bariatric Surgery
- Volunteers
- 40 people
- Sponsor
- Rio de Janeiro State University
Uterine Fibroids (UF)
Ultrasound-Guided Stellate Ganglion Block Plus Propofol for Perimenopausal Insomnia With Anxiety
Laparoscopic myomectomy is a commonly performed minimally invasive gynecologic procedure. However, surgical trauma, tracheal intubation, and pneumoperitoneum may induce pronounced perioperative stress responses, resulting in…
- Trial name
- SGB-PROP-PIA (NCT07384468)
- Testing
- Ultrasound-Guided Stellate Ganglion Block
- Where
- China
- Volunteers
- 233 people
- Sponsor
- Xiaochen Ji
Healthy, Healthy Adult
Assessment of Heart Rate Variability HRV During Descent DE From 2850m to Sea Level and During Re-ascent A From Sea Level to 2850m in Healthy Individuals H
To study the effect of relocation from high altitude (Quito Ecuador: 2850m) to sea level and re-ascent from sea level to 2850m on heart rate variability and other hemodynamic parameters in healthy individuals, who live…
- Conditions
- Healthy, Healthy Adult, High Altitude Effects, High Altitude
- Trial name
- NCT07801846
- Testing
- Descent and re-ascent (2850m, sea level)
- Where
- Switzerland
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Silvia Ulrich Somaini
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