Clinical trials: Variability
Prediabetes (Insulin Resistance, Impaired Glucose Tolerance), Artificial Intelligence Mobile Application
Food-i-Sense Analytics: Integrating AI Into Continuous Glucose Monitoring Data Analysis for Precision Nutrition.
This study aims to improve how we understand and manage blood sugar responses in adults without diabetes. Even in people who appear healthy, blood sugar levels after meals can behave in different ways.
- Trial name
- Food_i Sense (NCT07626658)
- Testing
- Continuous glucose monitoring using a wearable sensor (flash interstitial glucose monitor)
- Volunteers
- 471 people, healthy volunteers welcome
- Sponsor
- IMDEA Food
Prostate Cancer
Test-Retest Reproducibility of 18F-DCFPyL PET/CT in the Evaluation of Patients With Metastatic Prostate Cancer
In this study, the investigators intend to validate 18F-DCFPyL test-retest reproducibility in metastatic lesions, in order to investigate whether it serves as a reliable response assessment tool, both to interpret existing…
- Trial name
- NCT03793543
- Testing
- 18F-DCFPyL Injection
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Coronary Artery Disease
Using WHOOP Fitness Band to Measure Heart Health Variability Before and After Surgery
The goal of this observational study is to use the WHOOP device to measure heart rate variability (HRV) in patients with coronary artery disease (CAD) before and after they have CABG (coronary artery bypass graft) surgery.
- Trial name
- NCT07097168
- Where
- United States
- Sponsor
- Tufts Medical Center
Healthy
THE EFFECTS OF DIFFERENT BREATHING EXERCISES ON RESPIRATORY PARAMETERS AND HEART RATE VARIABILITY
Breathing is a vital process that occurs automatically, but it can also be voluntarily controlled to achieve specific goals, especially preventive and therapeutic ones.
- Trial name
- NCT07739238
- Testing
- breathing exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Bandırma Onyedi Eylül University
Diabetes Mellitus, Type 1
Assess the Impact of Insulclock on Glycemic Variability and Treatment Compliance in Uncontrolled DM1 Patients
Insulclock® is a small electronic device developed to facilitate the optimal administration of insulin. This device works as an add-on module of commercially available insulin pens and monitors the date, time and dose of…
- Trial name
- Segoclock2 (NCT04847778)
- Testing
- Use of Insulclock system, both Insulclock device and Insulclock 360 app., Use of Insulclock system, both Insulclock device and Insulclock app on masked mode.
- Where
- 4 sites in Spain
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Hospital General de Segovia
Interscalene Brachial Plexus Block
Changes in Pulse Wave Transit Time and Its Variability After Placement of Interscalene Brachial Plexus Block
Pulse wave transit time (PWTT) increases due to decreased arterial vascular tone resulting from sympathetic blockade caused by regional anesthesia.
- Trial name
- NCT05944497
- Testing
- Interscalene brachial plexus block
- Where
- South Korea
- Volunteers
- 59 people
- Sponsor
- JongHae Kim
Amyotrophic Lateral Sclerosis
Inspiratory Muscle Training With Powerbreath Device in Patients With ALS
Abstract: Context/background: people affected by Amyotrophic Lateral Sclerosis (ALS) see their own life totally disturbed after the diagnosis.
- Trial name
- NCT04889248
- Testing
- Inspiratory Muscle Training with Powerbreath IMT device.
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- Universidad Francisco de Vitoria
Caffeine, Heart Rate Variability
Effect of Caffeine on Heart Rate Variability in Newborns
The aim of this study was to evaluate the impact of caffeine treatment, given either orally or intravenously, on heart rate variability in newborns.
- Conditions
- Caffeine, Heart Rate Variability, Apnoea of Newborn, Newborn
- Trial name
- NCT04869176
- Testing
- Electrocardiogram, Monitoring of vital functions, Caffeine Citrate 5 mg/kg
- Where
- Slovenia
- Volunteers
- 25 people
- Sponsor
- University of Ljubljana
Intraoperative Monitoring, Hypovolemia
Interest of the Pleth Variability Index in Neurosurgery
This clinical trial aims to study the interest of the Pleth Variability Index (PVI) to evaluate perioperative fluid responsiveness in neurosurgery in adults.
- Conditions
- Intraoperative Monitoring, Hypovolemia, Fluid Challenge
- Trial name
- NCT06624891
- Testing
- perioperative fluid responsiveness with the Pleth variability index, perioperative fluid responsiveness with delta PP
- Where
- Tunisia
- Volunteers
- 70 people
- Sponsor
- National Institute of Neurology, Tunisia
Frailty in Adult Surgery
Functional Capacity Through HRV in Multimodal Rehabilitation for Adult Surgery
This prospective, observational cohort study investigates heart rate variability (HRV) monitoring using the Analgesia Nociception Index (ANI) monitor in adult patients undergoing major surgery within a multimodal rehabilitation…
- Trial name
- PreANI (NCT06436417)
- Testing
- Analgesia Nociception Index (ANI) Monitor, Trimodal Prehabilitation
- Where
- Spain
- Volunteers
- 490 people, healthy volunteers welcome
- Sponsor
- Investigation Group Anesthesia, Resuscitation, And Perioperative Medicine of Aragon
Diabetes, Diabetes Mellitus, Type 1
A Trial Investigating the Within-subject Variability of NN1250 in Subjects With Type 1 Diabetes
This trial is conducted in Europe. The aim of this clinical trial is to evaluate the variability in the blood glucose-lowering effect of NN1250 (insulin degludec) in subjects with type 1 diabetes.
- Trial name
- NCT00961324
- Testing
- insulin degludec, insulin glargine
- Where
- Germany
- Volunteers
- 54 people
- Sponsor
- Novo Nordisk A/S
Hip Arthroplasty, Knee Arthroplasty
Operative Hemodynamic Optimization Using the Plethysmographic Variability Index During Orthopedic Surgery
The purpose of this study is to determine whether an operative hemodynamic optimization using the plethysmographic variability index during orthopedic surgery could decrease the length of hospital stay and the postoperative…
- Conditions
- Hip Arthroplasty, Knee Arthroplasty, General Anesthesia
- Trial name
- OPVI (NCT02207296)
- Testing
- Plethysmographic variability index
- Where
- France
- Volunteers
- 440 people
- Sponsor
- University Hospital, Caen
Healthy
Osteopathic Manipulative Treatment and Its Relationship to Autonomic Nervous System Activity
The relationship between Osteopathic Manipulative Therapy (OMT) and the autonomic nervous system is poorly understood. This study quantifies that relationship and demonstrates a cause and effect.
- Trial name
- NCT00516984
- Testing
- OMT
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Caregiver Burden, Anxiety
Caring Relationships Expression Study
This study will examine a heart rate variability biofeedback (HRVB) intervention versus a music listening control (MLC) for 30 family caregivers (FCGs) of Alzheimer's disease (AD) (and related dementias: ADRD) patients to examine…
- Conditions
- Caregiver Burden, Anxiety, Stress
- Trial name
- CARES (NCT05627687)
- Testing
- Heart Rate Variability Biofeedback, Music Listening Control
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Arizona State University
Diabetes
Distinguishing Patient Groups Using Autonomic Dysfunction
A study population with impaired fasting glucose levels, impaired glucose tolerance levels and diabetes (with or without complications) along with healthy patients will be chosen as participants.
- Trial name
- NCT04964921
- Testing
- Device: ANSiScope Plus
- Volunteers
- healthy volunteers welcome
- Sponsor
- DyAnsys, Inc.
Primary Prevention, Stress
Efficacy of Taiji Training as a Program for Stress Prevention
Background: Excessive exposure to psychosocial stress can be a potent trigger for somatic diseases and psychological disorders, a cause for missing work, and eventually lead to high economic loss.
- Conditions
- Primary Prevention, Stress, Tai ji, Adult
- Trial name
- NCT01122706
- Testing
- Taiji training
- Where
- Switzerland
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of Bern
Heart Rate Variability
The Heart of the Community Study
Community service providers (CSPs), such as promotores and other community health staff, play an essential role in preserving health and treating disease in underserved Hispanic/Latinx (HL) communities with disproportionately…
- Trial name
- NCT05560893
- Testing
- Relational Savoring Intervention
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- University of California, Irvine
Angina Pectoris, Ischemic Heart Disease
Heart Rate Variability (HRV) Testing Compared With Exercise Stress Test in Hospitalized Patients With Chest Pain
There are many patients hospitalized for chest pain, which don't have high risk features that require invasive coronary angiography, but are considered intermediate risk and for which ischemic heart disease can not be excluded.
- Trial name
- NCT02530021
- Testing
- Heart rate monitor
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Meir Medical Center
Irritable Bowel Syndrome
Heart Rate Variability in Patients With Irritable Bowel Syndrome Before and After Gut-directed Hypnotherapy
Dysregulation of the brain-gut-axis is believed to underlie symptom generation in irritable bowel syndrome (IBS). The Autonomous Nervous System (ANS) is an important route of brain-gut communication and aberrant ANS functioning…
- Trial name
- NCT05283655
- Testing
- Gut-directed hypnotherapy
- Volunteers
- 17 people
- Sponsor
- Medical University of Vienna
Type 1 Diabetes (T1D)
Effects of Bedtime Snack Composition on Overnight Glucose in Children and Adolescents With Type 1 Diabetes
This study compared four types of bedtime snacks in children and adolescents with type 1 diabetes treated with multiple daily insulin injections.
- Trial name
- NCT07778147
- Testing
- Carbohydrate-Only Bedtime Snack, Carbohydrate-Plus-Protein Bedtime Snack, Carbohydrate-Plus-Fat Bedtime Snack
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Didem Güneş Kaya
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