Clinical trials: Variability
Cerebrovascular Accident
Heart Rate Variability and Orthostatic Hypotension in Stroke Patients Evaluated by Intelligent Biosensor System
This research investigated the heart rate variability (HRV) and stroke patients' orthostatic hypotension in hospitalized stroke patients accompanied with dizziness at varied tilting angle controlled by tilting table with…
- Trial name
- NCT02358252
- Where
- Taiwan
- Sponsor
- Changhua Christian Hospital
Prehypertension, Blood Pressure
HIRREM for Pre-Hypertension
This randomized, controlled clinical pilot trial will evaluate the effects associated with in-office use of closed-loop, acoustic stimulation neurotechnology (High-resolution, relational, resonance-based, electroencephalic…
- Conditions
- Prehypertension, Blood Pressure, Autonomic Nervous System Imbalance, Cardiovascular Risk Factor
- Trial name
- NCT03332043
- Testing
- HIRREM, Ambient Nature Sounds
- Sponsor
- Wake Forest University Health Sciences
Biomechanical; Lesion
INVESTIGATING THE EFFECTS SACROILIAC JOINT DYSFUNCTION ON GAIT IN INDIVIDUALS WITH BACK PAIN
Sacroiliac joint dysfunction (SJD) is a common problem in individuals with lumbar herniation nucleus pulposus (LHNP) plus back pain.
- Trial name
- NCT03426852
- Testing
- No intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Hacettepe University
Inflammatory Bowel Disease, Heart Rate Variability
Continuous HRV Monitoring for Predicting Response to Biologic Therapy in IBD
This is a prospective, multicenter, observational cohort study, which plans to enroll patients with active IBD who are scheduled to initiate IFX or VDZ treatment between October 2025 and October 2027 at Xijing Hospital, Tang-du…
- Conditions
- Inflammatory Bowel Disease, Heart Rate Variability, Biologics, Prediction
- Trial name
- NCT07475052
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Xijing Hospital
Healthy
Physiologic Effect of Spices Ingestion
Human studies have shown that capsaicin, a compound extracted from chilly peppers, can stimulate certain physiologic functions (for example, energy expenditure, thermogenesis, lipid oxidation, heart rate, etc.).
- Trial name
- NCT02193438
- Testing
- Spices intake
- Where
- Switzerland
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Société des Produits Nestlé (SPN)
Exposure to Man-made Visible Light
Systematically Assessing Effects of Colored Light on Humans With a Multi-modal Approach (Substudy 1 of 7)
NOTE: This is the first of in total 7 sub-studies related to the Ethics Committee of the Canton of Bern Ref. No. KEK-BE 2016-00674.
- Trial name
- NCT02882516
- Testing
- Visible light exposure
- Where
- Switzerland
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Bern
COVID-19, Fatigue
Differential Diagnosis of Persistent COVID-19 by Artificial Intelligence
The pandemic caused by SARS-CoV-2 infection has resulted, in addition to the well-known acute symptoms, in the emergence of persistent, diffuse and heterogeneous symptoms referred to as persistent COVID.
- Conditions
- COVID-19, Fatigue, Distress Respiratory Syndrome, Cognitive Dysfunction
- Trial name
- DICOPERIA (NCT05629793)
- Testing
- Experimental tests
- Where
- 7 sites in Spain
- Volunteers
- 136 people
- Sponsor
- Fundacin Biomedica Galicia Sur
Atrial Fibrillation, Heart Failure, Systolic
Machine Learning Enabled Time Series Analysis in Medicine
The goal of this observational cohort study is to investigate the potential of fitness trackers in combination with machine learning algorithms to identify cardiovascular disease specific patterns.
- Trial name
- ME-TIME (NCT05802563)
- Testing
- fitness tracker
- Where
- Netherlands
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- HagaZiekenhuis
Sedentary Behavior, Frailty
Effects of Intermittent Hypoxia-Hyperoxia in Older Adults
The supply of oxygen is essential for energy production, recovery from efforts, and human life. Intermittent Hypoxia-Hyperoxia Exposure (IHHE) is a novel technique in which the subject is exposed to a respiratory environment with…
- Conditions
- Sedentary Behavior, Frailty, Older Adults
- Trial name
- NCT06686316
- Testing
- Device: Hypoxic Gas Mixture
- Volunteers
- 16 people
- Sponsor
- Sierra Varona SL
Exposure to Man-made Visible Light
Systematically Assessing Effects of Colored Light on Humans With a Multi-modal Approach (Substudy 5 of 7)
NOTE: This is the fifth of in total 7 sub-studies related to the Ethics Committee of the Canton of Bern Ref. No. KEK-BE 2016-00674.
- Trial name
- NCT02919189
- Testing
- Visible light exposure
- Where
- Switzerland
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Bern
Tuberculosis
Monthly Follow up of Interferon Gamma Releasing Assay (IGRA) Among Health-care Workers Treating Tuberculosis (TB) Patients
Interferon gamma releasing assay(IGRA) is useful to diagnose latent tuberculosis. However,IGRA responses could show within-subject variability.
- Trial name
- NCT01121068
- Testing
- Blood samplings
- Where
- South Korea
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Type 2 Diabetes Mellitus
Study for Beinaglutide Versus Glargine Therapy in Glycemic Variability of Type 2 Diabetes Mellitus
The investigators aimed to assess the efficacy and safety of Beinaglutide versus glargine , in individuals with type 2 diabetes who did not achieve adequate glycaemic control with oral antidiabetic drug.
- Trial name
- NCT03829891
- Testing
- Beinaglutide, glargine
- Where
- 2 sites in China
- Volunteers
- 60 people
- Sponsor
- Xijing Hospital
Congestive Heart Failure, Chronic Kidney Diseases
Within Subject Variability Study of ER Torsemide 20 mg Tablet in Healthy Subjects
The study will evaluate the within-subject variability of 20mg ER torsemide as compared to 20mg IR torsemide (Demadex) in fully replicate double-crossover trial in healthy volunteers, who are consuming a high-salt diet (300…
- Trial name
- NCT03214874
- Testing
- Demadex 20mg Tablet, ER Torsemide 20mg Tablet
- Where
- India
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Sarfez Pharmaceuticals, Inc.
Pain
Patient and Provider Confidence and Satisfaction With the Clinical Use of CYP Genetic Variability
This study utilizes the Medication DNA Insight™ tests for pain and mental health medications. We are testing the pain and mental health medications commonly used in pain treatment.
- Trial name
- Genomics (NCT02568618)
- Testing
- Pain Medication DNA Insight (TM) test
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Defense and Veterans Center for Integrative Pain Management
Psychological Stress, Anxiety
NeuroFinance Human Stress Trial During Financial and Informational Volatility
The NeuroFinance Human Stress Trial (NFHST-2026-001) is a decentralized observational clinical study designed to evaluate how financial market volatility, economic uncertainty, digital media exposure, and information-driven…
- Conditions
- Psychological Stress, Anxiety, Emotional Stress, Autonomic Nervous System Dysfunction
- Trial name
- NFHST (NCT07622589)
- Testing
- Wearable Physiologic Monitoring Platform
- Where
- United States
- Volunteers
- 2,500 people, healthy volunteers welcome
- Sponsor
- Truway Health, Inc.
Diabetes
Distinguishing Participant Groups Using Autonomic Dysfunction
A study population with impaired fasting glucose levels, impaired glucose tolerance levels and diabetes (with or without complications) along with healthy patients will be chosen as participants.
- Trial name
- NCT05199350
- Testing
- Device Name: ANSiscope
- Where
- India
- Volunteers
- 175 people, healthy volunteers welcome
- Sponsor
- DyAnsys, Inc.
Autonomic Nervous System Imbalance, Heart Rate Variability (HRV)
Evaluating the Feasibility, Acceptability, and Preliminary Outcomes of Heart Rate Variability Biofeedback for Individuals With Opioid Use Disorder.
The goal of this clinical trial is to evaluate the feasibility, acceptability, and preliminary outcomes of a heart rate variability biofeedback (HRVB) intervention among adults with opioid use disorder (OUD) receiving residential…
- Conditions
- Autonomic Nervous System Imbalance, Heart Rate Variability (HRV), Opioid Use Disorder, Breathing Techniques
- Trial name
- NCT07361731
- Testing
- Heart rate variability biofeedback
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Arizona State University
Pelvic Anatomy, Retroperitoneum
Systematic Anatomical Description of the Female Pelvic Retroperitoneum in Cadavers
This observational descriptive cadaveric study aims to describe the main anatomical relationships of the female pelvic retroperitoneum using standardized anatomical dissection.
- Conditions
- Pelvic Anatomy, Retroperitoneum, Cadaveric Study, Surgical Anatomy
- Trial name
- RETRO-PELVIS (NCT07522931)
- Testing
- Anatomical Dissection
- Where
- 2 sites in Spain
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Hospital Universitari de Bellvitge
Baro-reflex Sensitivity, Heart Rate Variability
Low Intensity Exercise in Different Normobaric/Hypobaric Normoxic/Hypoxic Conditions.
The main goal of this project is to investigate how low intensity cycling exercise (1.5W/kg, for 6 minutes) influences cerebral functions, such as: Cerebral blood flow, oxygenation, and other physiological variables in different…
- Conditions
- Baro-reflex Sensitivity, Heart Rate Variability, EEG, Microstates, Cerebral Blood Flow Regulation
- Trial name
- Hypoxia (NCT03439202)
- Testing
- Hypoxia
- Where
- Switzerland
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Fliegerärztliches Institut
Occupational Health, Autonomic Nervous System (ANS) Functioning and Mood State
Office Massage Effects on HRV and Stress
This study is a randomized controlled trial designed to investigate which of three short office massage types (head, neck/shoulder area, or hand) is most effective for reducing chronic stress in women who perform sedentary office…
- Conditions
- Occupational Health, Autonomic Nervous System (ANS) Functioning and Mood State, Stress
- Trial name
- NCT07272031
- Testing
- Head Massage Intervention, Cervical Area Massage Intervention, Hand Massage Intervention
- Where
- Latvia
- Volunteers
- 140 people
- Sponsor
- Riga Stradins University
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