Clinical trials: Variceal Bleeding, Cirrhosis
Cirrhosis, Liver, Gastroesophageal Varices
Development of 4D Flow MRI for Risk Stratification of Variceal Bleeding in Cirrhosis
The goal of this research is to validate novel non-invasive Magnetic resonance imaging (MRI) biomarkers to detect Gastroesophageal varices (GEV) in patients with cirrhosis, including fractional flow change in the portal vein and…
- Conditions
- Cirrhosis, Liver, Gastroesophageal Varices, Fontan Procedure
- Trial name
- NCT04867954
- Testing
- Ensure Plus®, Pre-clinical validation contrast enhanced MRI, Clinical validation MRI
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Coagulation Disorder, Cirrhosis, Liver
Heparin Like Effect in Acute Variceal Bleeding
This study attempts to clarify the pathophysiology of haemostasis in relation to the evidence of sepsis in liver disease, and compares the accuracy of various available laboratory tests in assessment of these patients.
- Conditions
- Coagulation Disorder, Cirrhosis, Liver, Variceal Hemorrhage
- Trial name
- NCT04111120
- Testing
- SONOCLOT, coagulation factor assays for VIII/X, XIII, TPA/ PAI
- Where
- India
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Esophageal Varices in Cirrhosis of the Liver
Radiomics-based Surrogate of Endoscopy (rEndosc) (CHESS1703)
Esophageal varices (EVs) resulting from portal hypertension are a prevalent complication of cirrhosis with a high mortality when variceal hemorrhage (VH) occurs.
- Trial name
- rEndosc (NCT03373123)
- Testing
- Endoscopy, CTA
- Where
- 9 sites in China
- Volunteers
- healthy volunteers welcome
- Sponsor
- Nanfang Hospital, Southern Medical University
Esophageal and Gastric Varices
Comparison of Endoscopic Band Ligation Plus 24-hour Versus 72-hour Terlipressin Therapy
In the Western world, liver cirrhosis is a significant issue. Acute variceal bleeding (AVB) is a considerable complication of cirrhosis associated with high mortality.
- Trial name
- NCT05331768
- Testing
- banding ligation plus terlipressin infusion
- Where
- Mexico
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- Instituto Mexicano del Seguro Social