Clinical trials: Varicose Vein Disease
Colon Polyp, Colon Disease
Endoscopy-related Phone Consultation During the COVID-19 Outbreak
The aim of this study is to evaluate patient and consultant experiences with phone consultations for endoscopy-related outpatient appointments during the COVID-19 outbreak.
- Conditions
- Colon Polyp, Colon Disease, Reflux, Gastroesophageal, Varices, Esophageal
- Trial name
- NCT04344964
- Testing
- None - NA
- Where
- Australia
- Volunteers
- 186 people, healthy volunteers welcome
- Sponsor
- Austin Health
Esophageal Varices, Non-alcoholic Fatty Liver
Non-invasive Prediction of Esophageal Varices in Patients With Non-Alcoholic Fatty Liver Disease With Advanced Fibrosis
Non-alcoholic fatty liver disease (NAFLD) is defined as accumulation of fat in the liver which is not related to either alcohol excess or other causes such viral infection, immune-mediated, or medication related which can lead to…
- Conditions
- Esophageal Varices, Non-alcoholic Fatty Liver, Compensated Cirrhosis
- Trial name
- NCT05485714
- Testing
- Reviewing records retrospectively of patients undergoing screening endoscopy
- Where
- United Arab Emirates
- Volunteers
- 73 people
- Sponsor
- United Arab Emirates University
Venous Stasis Ulcers, Venous Insufficiency
Taliderm Dressing for Venous Ulcers
The study will test a new wound healing dressing called Taliderm® on leg ulcers caused by chronic venous insufficiency (CVI). Some people with CVI have poor vein circulation that causes ulcers to develop on the lower legs.
- Trial name
- NCT00720239
- Testing
- Taliderm wound healing dressing
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Medical University of South Carolina
Diabetic Foot Ulcers, Venous Stasis Ulcer
Negative Pressure Wound Therapy Registry
The goal of the Negative Pressure Wound Therapy Registry (NPWTR) for Wounds is to provide real world patient data from electronic health records submitted to meet Stage 2 Meaningful Use in order to understand the effectiveness…
- Conditions
- Diabetic Foot Ulcers, Venous Stasis Ulcer, Pressure Ulcer, Surgical Wound Dehiscence
- Trial name
- NPWTR (NCT02467998)
- Testing
- NPWT
- Where
- United States
- Volunteers
- 50,000 people
- Sponsor
- U.S. Wound Registry
Cirrhosis, Portal Hypertension
Efficacy of Long-acting Octreotide (Sandostatin LAR) in Reducing Portal Pressure in Patients With Cirrhosis
Octreotide is used to control variceal bleeding. However, octreotide has to be given through the vein and is effective for less than two hours.
- Conditions
- Cirrhosis, Portal Hypertension, Esophageal Varices
- Trial name
- NCT01188733
- Testing
- Long acting octreotide 10mg, Long acting Octreotide 30mg, Saline
- Volunteers
- 39 people
- Sponsor
- Mayo Clinic
Varicose Veins
Treatment of Saphenous Vein Reflux With 1920-nm Diode Laser
Objective: Compare venous occlusion rates at a one-year follow-up comparing 1920-nm versus 1470-nm laser treatment. Design: Non-randomized prospective study.
- Trial name
- NCT02504684
- Testing
- Endovenous 1920-nm diode laser, Endovenous 1470-nm diode laser
- Where
- Brazil
- Volunteers
- 67 people
- Sponsor
- Instituto Vascular BH
Healthy Adults, Venous Leg Ulcer
Pressure and Temperature Sensor for Therapeutic Compression Garments
Pilot study of a soft, flexible pressure and temperature sensor
- Trial name
- NCT03461549
- Testing
- Pressure and Temperature Sensor
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Venous Leg Ulcer
Intermittent Pneumatic Compression of the Foot vs Geko Plus R-2 Neuromuscular Electrostimulation Device in Venous Leg Ulcer Patients
Chronic venous leg ulcers (VLU) are painful, debilitating wounds that place a significant burden on the patient, their family, and healthcare resources.
- Trial name
- NCT02912858
- Testing
- geko plus R-2
- Sponsor
- Firstkind Ltd
Varicose Veins of Lower Limb, Spider Veins
CLaCS Using 0.2% Aetoxysklerol Foam and 70% Glucose for the Treatment of Lower Limb Telangiectasias
This randomized, controlled, non-inferiority trial aims to compare the efficacy of two sclerosants used in the CLaCS (CryoLaser and CryoSclerotherapy) method for treating telangiectasias and reticular varicose veins.
- Conditions
- Varicose Veins of Lower Limb, Spider Veins, Reticular Leg Veins
- Trial name
- CLACSO (NCT07073742)
- Testing
- CLaCS
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Charles University, Czech Republic
Chronic Wounds, Diabetes
FGF-1 for Topical Administration for the Treatment of Diabetic or Venous Stasis Ulcers
FGF-1 is being used for the treatment of patients with diabetic or venous stasis ulcers. Procedure includes topical administration of FGF-1 or placebo and evaluation of safety, pharmacokinetics, and wound improvement.
- Conditions
- Chronic Wounds, Diabetes, Venous Stasis Ulcers
- Trial name
- NCT00425178
- Testing
- FGF-1
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Venturis Therapeutics, Inc.
Varicose Ulcer
Wound Dressings Adapted to Wound Exudate and Bacterial Load in Therapy Resistant Large Sized Leg Ulcers
The purpose of the study was to investigated if modern wound dressings adapting to wound exudation and the amount of bacterial colonization can heal large therapy resistant leg ulcers which had a pre-treatment with compresses…
- Trial name
- NCT00349700
- Testing
- Compression: 2 weeks four layer bandages, then stockings, debridement, Actisorb plus (r) + Trionic(r)/ Allevyn (r)
- Where
- Germany
- Volunteers
- 139 people
- Sponsor
- Ruhr University of Bochum
Chronic Venous Insufficiency
Radiofrequency Ablation vs. Laser Ablation of the Incompetent Small Saphenous Vein
The aim of this study is to perform a randomized, prospective trial comparing the two current methods of treatment for chronic venous insufficiency related to the Small Saphenous Vein (SSV) to evaluate complications and outcomes…
- Trial name
- NCT02248740
- Testing
- Ablation of the incompetent small saphenous vein
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Virginia Commonwealth University
Hard-to-heal Wounds, Diabetic Foot Ulcer
Clinical Investigation of Sorbact® Dressings
The main purpose of this exploratory clinical investigation is to study the binding of bacteria and fungi from hard-to-heal wounds to the DACC-coated dressings.
- Conditions
- Hard-to-heal Wounds, Diabetic Foot Ulcer, Venous Leg Ulcer, Pressure Ulcer
- Trial name
- NCT05089890
- Testing
- Sorbact® Compress, Sorbact® Gel Dressing, Sorbact® Ribbon Gauze
- Where
- Sweden
- Volunteers
- 30 people
- Sponsor
- ABIGO Medical AB
Venous Leg Ulcer
Pilot Study Comparing Negative Pressure Dressings to Conventional Dressings
This study is being conducted to determine how the PICO™ Negative Pressure Wound Therapy compares to standard care treatment for venous stasis ulcers, as there is no evidence to date.
- Trial name
- NCT03450616
- Testing
- PICO Negative Pressure Wound Therapy, Compression Dressing
- Where
- United States
- Sponsor
- Northwell Health
Varicosity
Elastic Compression in Chronic Venous Disease
Patients with chronic venous disease causing pain or ache will be randomised into two groups, active stockings (18-21 mmHg) or placebo stockings
- Trial name
- RECVEN (NCT02641600)
- Testing
- Elastic stockings
- Where
- Greece
- Volunteers
- 30 people
- Sponsor
- University of Patras
Venous Leg Ulcer, Diabetic Foot Ulcer
Clinical Performance and Cost Effectiveness of Biatain® Silicone Compared With Standard of Care
A randomised controlled investigation comparing the clinical performance and cost effectiveness of Biatain® Silicone with Standard of Care dressing including filler in chronic wounds (CP351 - BISIL Study) This study (BISIL) will…
- Trial name
- BISIL (NCT05786612)
- Testing
- Biatain® Silicone, Mepilex Border with Aquacel Extra Hydrofiber
- Where
- 9 sites in United Kingdom
- Volunteers
- 102 people
- Sponsor
- Coloplast A/S
Chronic Hepatitis C, Cirrhosis
Impact of Antiviral Therapy on Gastroesophageal Varices.
Hepatitis C virus (HCV) chronic infection affects 200 million people worldwide. HCV antiviral treatment has evolved rapidly since 2011.
- Trial name
- NCT02758509
- Testing
- Pegylated interferon alfa-2a + Ribavirin, Pegylated interferon alfa-2a + Ribavirin + Boceprevir, Pegylated interferon alfa-2a + Ribavirin +Telaprevir
- Volunteers
- 237 people
- Sponsor
- Parc de Salut Mar
Leg Ulcer, Veins, Varicose
Effect of PEM Treatment of Superficial Axial and Tributary Vein Reflux on Improvement of Wound Healing in VLUs
This study evaluates the addition of polidocanol endovenous microfoam (PEM) to compression therapy to determine effectiveness in improving the healing of venous leg ulcers (VLUs) in adults with severe venous disease of the great…
- Conditions
- Leg Ulcer, Veins, Varicose, Venous Ulcer, Reflux
- Trial name
- NCT02988063
- Testing
- Polidocanol Endovenous Microfoam (PEM)
- Where
- United States
- Sponsor
- OhioHealth
Venous Insufficiency, Oedema
REVITIVE for the Treatment of Patients With Venous Insufficiency
To investigate the efficacy of an electrical stimulation (using the REVITIVE IX device) in treating patients with venous insufficiency.
- Conditions
- Venous Insufficiency, Oedema, Varicose Veins
- Trial name
- RVI (NCT02114307)
- Testing
- REVITIVE IX
- Where
- United Kingdom
- Volunteers
- 22 people
- Sponsor
- Imperial College London
Venous Insufficiency of Leg, Venous Leg Ulcer
Non Contrast MRI in Lower Extremity
We collected retrospectively the non contrast MRI in chia yi memorial hospital for different venous disease of lower extremity morphology and flow ananlysis were done.
- Conditions
- Venous Insufficiency of Leg, Venous Leg Ulcer, Venous Occlusion, Contrast Media Reaction
- Trial name
- NCT04995432
- Where
- Taiwan
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital