Clinical trials: Varus Malalignment
ACL - Anterior Cruciate Ligament Deficiency, Varus Deformity of Tibia (Disorder)
Patients With Acl Injury and Varus Knee Will Undergo Acl Reconstruction Alone, or Combined With High Tibial Osteotomy in the Same Session.
The purpose of this study is to compare the results of single-stage anterior cruciate ligament reconstruction combined with high tibial osteotomy and anterior cruciate ligament reconstruction alone in knees with varus…
- Conditions
- ACL - Anterior Cruciate Ligament Deficiency, Varus Deformity of Tibia (Disorder), ACL Injury, Knee Deformity
- Trial name
- NCT05817084
- Testing
- medial opening wedge high tibial osteotomy, anterior cruciate ligament reconstruction
- Where
- Egypt
- Volunteers
- 24 people
- Sponsor
- Mostafa Hassanein, Msc
Osteoarthritis, Varus Malalignment
Ellipse Intramedullary High Tibial Osteotomy Nail Study
The purpose of this study is to collect outcomes data in patients implanted with the Ellipse IM HTO Nail System.
- Trial name
- NCT02519218
- Testing
- Ellipse Technologies Intramedullary High Tibial Osteotomy Nail System
- Volunteers
- 6 people
- Sponsor
- Ellipse Technologies, Inc.
Osteoarthritis, Malalignment
Local Infiltration Versus Block Against Pains After High Tibial Osteotomy
The purpose of this study is to elucidate whether patients operated with high tibia open-wedge osteotomy for osteoarthritis of the knee can be treated more appropriately, so that both healing and rehabilitation are served…
- Trial name
- HTO_pains (NCT01537146)
- Testing
- Ropivacaine
- Where
- Denmark
- Volunteers
- 60 people
- Sponsor
- Northern Orthopaedic Division, Denmark
Osteoarthritis, Varus Malalignment
Computerized Tomography (CT) Scan Study of Bone Healing Following Open Wedge Proximal Tibial Osteotomy
The purpose of this study is to assess whether there is a difference between the TomoFix and Ellipse Intramedullary HTO Nail System in terms of bone regeneration in the tibial wedge by performing a CT-scan at 3 and 6-months…
- Trial name
- CISKO (NCT03431662)
- Testing
- Ellipse IM HTO Nail, TomoFix
- Where
- United Kingdom
- Volunteers
- 12 people
- Sponsor
- Ellipse Technologies, Inc.
Valgus Malalignment of the Knee
Open Versus Closed Wedge Distal Femoral Varus Osteotomy for the Valgus Knee. Indications, Clinical and Radiological Outcome
This study is to analyze the indications of the two most popular techniques of distal femoral osteotomy (DFO) performed in patients with valgus malalignment and symptomatic degenerative changes in the lateral compartment of the…
- Trial name
- Var_DFO (NCT04382118)
- Testing
- Data collection from routine medical records
- Where
- Switzerland
- Volunteers
- 22 people
- Sponsor
- University Hospital, Basel, Switzerland
Osteoarthritis, Varus Malalignment
Ellipse Intramedullary Nail High Tibial Osteotomy Study
This study further evaluates the safety profile and efficacy of the Ellipse IM HTO Nail system in subjects with osteoarthritis and varus malalignment of the knee.
- Trial name
- IM HTO (NCT02412163)
- Testing
- Ellipse IM HTO Nail
- Where
- 11 sites in Germany, Netherlands and 2 more
- Volunteers
- 41 people
- Sponsor
- Ellipse Technologies, Inc.
Knee Osteoarthritis (Kellgren-Lawrence Grade 1-3)
Targeted Rehabilitation Versus Standard Care in Managing Medial Knee Pain and Varus Malalignment: A Randomized Control Trial
Medial knee pain with varus alignment is common in active adults and is associated with increased medial joint loading, cartilage loss, and progression of knee osteoarthritis.
- Trial name
- NCT07410429
- Testing
- Conventional Knee Physical Therapy Program, Targeted Alignment-Focused Exercise Program for Varus Knee
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Assiut University
Knee Osteoarthritis, Cartilage Degeneration
Impact of High Tibial Osteotomy in Preventing Degenerative Disease Progression in Medial Knee Osteoarthritis.
High tibial osteotomy (HTO) surgical procedure can lead to clinically significant improvements in the cartilage and in subchondral bone quality, with a slow down of the osteoarthritis (OA) progression.
- Conditions
- Knee Osteoarthritis, Cartilage Degeneration, Malalignment, Bone
- Trial name
- HTO-IOR (NCT05865899)
- Testing
- valgus producing medial opening wedge high tibial osteotomy
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- Istituto Ortopedico Rizzoli
Bone Malalignment
CT Imaging Study for Knee Osteotomy (CISKO)
Malalignment of the knee joint causes arthritis in later life. Currently there are three surgical ways to treat knee arthritis: total knee replacement, partial knee replacement, and high tibial osteotomy (HTO).
- Trial name
- CISKO (NCT02717845)
- Testing
- Ellipse, Tomofix
- Where
- United Kingdom
- Volunteers
- 10 people
- Sponsor
- North Cumbria University Hospitals NHS Trust