Clinical trials: Vascular
Arterial Hypertension
Aliskiren on Retinal Vasculature Treatment Study
Hypertension affects approximately one fourth of the world population and therefore contributes substantially to the worldwide burden of cardiovascular (CV) disease and end-organ damage.
- Trial name
- ARTS (NCT01318395)
- Testing
- Aliskiren
- Where
- 2 sites in Germany
- Volunteers
- 56 people
- Sponsor
- University of Erlangen-Nürnberg Medical School
Stroke
Assessment of an Intensive Motor Telerehabilitation Program for Stroke Patients
Stroke is a major cause of motor disability, particularly hemiplegia, and its incidence is increasing as the population ages. Despite partial spontaneous recovery in the first three months, 80% of patients retain a motor deficit…
- Trial name
- REACT-AVC (NCT07254195)
- Testing
- Telerehabilitation program using the MindMotion GO device
- Where
- France
- Volunteers
- 51 people
- Sponsor
- Hospices Civils de Lyon
Moyamoya Disease
Remimazolam Consumption: TCI vs. Manual Infusion
The purpose of this prospective randomized controlled trial is to compare the total consumption of remimazolam between two different administration methods-Target-Controlled Infusion (TCI) and manual infusion-in patients…
- Trial name
- NCT07377695
- Testing
- Target-Controlled Infusion (TCI) of Remimazolam, Manual Infusion of Remimazolam
- Where
- South Korea
- Volunteers
- 58 people
- Sponsor
- Seoul National University Hospital
Stroke, Gait Disorders, Neurologic
High Vs Low Intensity Virtual Reality Gait Training in Individuals with Chronic Stroke
The purpose of this pilot study is to investigate the feasibility of 1) providing virtual reality walking training using a custom developed setup able to be replicated in routine clinical practice and 2) combining the virtual…
- Trial name
- NCT06522477
- Testing
- Virtual reality gait training
- Where
- United States
- Sponsor
- Indiana University
Intracerebral Hemorrhage
Edaravone Dexborneol for Treatment of Hypertensive Intracerebral Hemorrhage
pending
- Trial name
- ED-ICH (NCT04714177)
- Testing
- Edaravone Dexborneol
- Volunteers
- 390 people
- Sponsor
- First Affiliated Hospital, Sun Yat-Sen University
Abdominal Aortic Aneurysm, Thoracoabdominal Aortic Aneurysm
Safety and Efficacy of Endovascular Repair of Complex Aortic Pathology With Physician-modified Endovascular Grafts (PMEGs)
The primary objective of this study is to examine the safety and effectiveness of physician-modified endovascular grafts (PMEGs) for endovascular repair of complex aortic pathology in high-risk patients.
- Conditions
- Abdominal Aortic Aneurysm, Thoracoabdominal Aortic Aneurysm, Aortic Dissection
- Trial name
- NCT04746677
- Testing
- Endovascular aortic repair with a physician-modified endovascular graft (PMEG), TREO graft
- Where
- United States
- Volunteers
- 220 people
- Sponsor
- Beth Israel Deaconess Medical Center
Peripheral Arterial Disease
Study of NMB Drug Ejecting Balloon for Peripheral Arteries
The purpose of this study is to demonstrate the Safety and effectiveness of the use of NMB's drug ejecting balloon for the treatment of de novo and restenotic lesions in peripheral arterial disease.
- Trial name
- NCT01646801
- Testing
- NMB Balloon Catheter
- Where
- Israel
- Volunteers
- 20 people
- Sponsor
- N.M.B. Medical Applications Ltd
Acute Coronary Syndromes
Impact of Non-medicalized ECG Practices Initiated by SAMU in Dispatch Strategies
The performance of an ECG by non-medicalized prehospital teams (firefighters, first responders, paramedic ambulances) is developing across the territory to cope with the increasing demand (SAMU calls) for a service that cannot…
- Trial name
- ECG-PHNM (NCT07144059)
- Testing
- ECG by the SMUR after medical interrogation by the SAMU, ECG performed by a non-medical vector
- Volunteers
- 350 people
- Sponsor
- Centre Hospitalier Sud Francilien
ST Elevation (STEMI) Myocardial Infarction of Other Sites, Repolarization Indices
Relation of Total Ischemic Time to Repolarization Indices and Their Impact on Outcomes Among STEMI Patients Undergoing Primary PCI
1. Evaluate The impact of early versus late presentation on electrocardiographic ventricular repolarization indices. 2. To assess the association between repolarization indices among early, late presentation in relation to…
- Conditions
- ST Elevation (STEMI) Myocardial Infarction of Other Sites, Repolarization Indices, Total Ischemic Time, Primary Percutaneous Coronary Intervention
- Trial name
- NCT07175259
- Testing
- Echocardiography
- Volunteers
- 500 people
- Sponsor
- Assiut University
Acoustic Schwannoma, Adult Anaplastic Meningioma
Bevacizumab in Treating Patients With Recurrent or Progressive Meningiomas
RATIONALE: Monoclonal antibodies, such as bevacizumab, can block tumor growth in different ways. Some block the ability of tumor cells to grow and spread.
- Conditions
- Acoustic Schwannoma, Adult Anaplastic Meningioma, Adult Ependymoma, Adult Grade I Meningioma
- Trial name
- NCT01125046
- Testing
- bevacizumab
- Where
- 5 sites in United States
- Volunteers
- 50 people
- Sponsor
- Northwestern University
Essential Hypertension
A Study to Evaluate the Pharmacokinetics and the Safety After Administration of BR1015-A and Co-administration of BR1015-1 and BR1015-2 Under Fed Conditions
The purpose of this clinical trial is to evaluate the pharmacokinetics and the safety after administration of BR1015-A and co-administration of BR1015-1 and BR1015-2 in healthy volunteers under fed conditions
- Trial name
- NCT07421388
- Testing
- BR1015-A, BR1015-1, BR1015-2
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Boryung Pharmaceutical Co., Ltd
Stroke
Perturbation Training for Fall-risk Reduction Among Stroke Survivors
The long-term objective of this research is to develop an efficacious training paradigm to enhance stroke survivors' defense mechanisms against falls and possibly reduce healthcare cost.
- Trial name
- NCT03205527
- Testing
- Overground slip perturbation training
- Where
- United States
- Volunteers
- 91 people
- Sponsor
- University of Illinois Chicago
Chronic Wounds, Burns
THERAVEX Tissue Care Spray Plus for the Management of Cutaneous Wounds, Burns, and Chronic Ulcers
Pilot observational clinical evaluation assessing the safety and potential effectiveness of THERAVEX Tissue Care Spray Plus as an adjunctive topical therapy for the management of cutaneous wounds, burns, traumatic lesions…
- Conditions
- Chronic Wounds, Burns, Pressure Ulcer, Traumatic Wounds
- Trial name
- NCT07617961
- Testing
- THERAVEX TISSUE CARE SPRAY PLUS
- Where
- Spain
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Biointelligent Technology Systems SL
Behcet Syndrome, Uveitis
Tocilizumab for the Treatment of Refractory Behcet's Uveitis
The aim of this single-center prospective study is to evaluate the efficacy and safety of Tocilizumab (TCZ), humanized monoclonal antibody against IL-6receptor, in the treatment of refractory Uveitis of Behçet's disease (BDU), to…
- Trial name
- NCT03554161
- Testing
- Tocilizumab (TCZ)
- Where
- China
- Volunteers
- 3 people
- Sponsor
- Wenjie Zheng
Angina Patients With Non-obstructive Coronary Artery Disease
Exercise Therapy for Women With ANOCA
Angina is a feeling of chest pain or discomfort which can happen if there is reduced blood flow to the heart. Patients can experience angina with no obstructive coronary arteries (ANOCA) which is a difficult condition to treat…
- Trial name
- ANOCA Exercise (NCT07733986)
- Testing
- Resistance based exercise
- Where
- 11 sites in United Kingdom
- Volunteers
- 76 people
- Sponsor
- NHS Greater Glasgow and Clyde
Venipuncture
Clinical Evaluation of an AI- and Ultrasound-Assisted Venipuncture Device
Purpose : This study aims to confirm the safety and efficacy of AIIV L2, an artificial intelligence- and ultrasound-based medical device that assists venipuncture, by comparing venipuncture performed using AIIV L2 with manual…
- Trial name
- NCT07383870
- Testing
- AIIV L2, Manual venipuncture
- Where
- South Korea
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Hypertension in Pregnancy, Pre-Eclampsia
Mobile Health Interventions to Prevent Heart Disease After Hypertensive Disorders of Pregnancy
The purpose of this research is to study digital health interventions to prevent cardiovascular disease in individuals who have had a hypertensive disorder of pregnancy (HDP).
- Conditions
- Hypertension in Pregnancy, Pre-Eclampsia, Eclampsia, Gestational Hypertension
- Trial name
- mHEART (NCT06523569)
- Testing
- Digital Blood Pressure Monitoring System, Mobile health application
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Northwestern University
Stroke, Acute Ischemic
COlombia DAISe FEasibility Exercise
This study is to assess initial safety and performance data of the DAISe Thrombectomy Device for removal of thrombus during an acute ischemic stroke.
- Trial name
- COFEE (NCT05631483)
- Testing
- DAISe
- Where
- Colombia
- Volunteers
- 2 people
- Sponsor
- MIVI Neuroscience, Inc.
Wounds, Wound of Skin
A Clinical Investigation to Follow the Progress of Exuding Chronic Wounds Using Mepilex® Up as the Primary Dressing.
The goal of this clinical trial is to follow the progress of wounds in those with venous leg ulcers and diabetic foot ulcers while using an absorbent dressing called Mepilex Up.
- Conditions
- Wounds, Wound of Skin, Wound Leg, Wound; Foot
- Trial name
- NCT05588583
- Testing
- Mepilex Up
- Where
- 4 sites in United States
- Volunteers
- 68 people
- Sponsor
- Molnlycke Health Care AB
COVID-19, Post-acute COVID-19 Syndrome
Hemostatic Profile of Post COVID-19/Long COVID-19 Patients
The present study aims at assessing long-term hemostatic profile of patients recovered from COVID-19 acute infection that remain asymptomatic (POST-COVID) versus patients with residual symptoms (LONG-COVID) through the employment…
- Trial name
- LCV (NCT05721066)
- Testing
- ClotPro assessment, Laboratory analysis, Interview
- Where
- Italy
- Volunteers
- 102 people
- Sponsor
- IRCCS Policlinico S. Donato
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