Clinical trials: Vascular Access
Complication of Renal Dialysis, End Stage Renal Disease
A Study Testing the Use of a Perivascular Sirolimus Formulation (Sirogen) in ESRD Patients Undergoing AV Fistula Surgery
The primary study objective is to evaluate the benefit of the Sirolimus eluting Collagen implant (SeCI; Sirogen), a single dose prophylactic treatment delivered intraoperatively at the time of surgical creation of an…
- Conditions
- Complication of Renal Dialysis, End Stage Renal Disease, End Stage Kidney Disease, ESRD
- Trial name
- ACCESS2 (NCT05425056)
- Testing
- Sirolimus
- Where
- 22 sites in United States, United Kingdom
- Volunteers
- 136 people
- Sponsor
- Vascular Therapies, Inc.
Renal Failure, End Stage Renal Disease
Comparison of the Human Acellular Vessel (HAV) With ePTFE Grafts as Conduits for Hemodialysis
The main purpose of this study is to compare the Human Acellular Vessel (HAV) with ePTFE grafts when used for hemodialysis access.
- Conditions
- Renal Failure, End Stage Renal Disease, Hemodialysis, Vascular Access
- Trial name
- NCT02644941
- Testing
- Human Acellular Vessel (HAV), ePTFE graft
- Where
- 38 sites in United States, Germany and 4 more
- Volunteers
- 355 people
- Sponsor
- Humacyte, Inc.
Intraosseous Vascular Access, Vascular Access
Follow-Up Study Validating a Blended Technique to Identify the Proximal Humerus Intraosseous Vascular Access Site
A Follow-up Study Validating a Blended Technique for Identifying the Proximal Humerus Intraosseous Vascular Access Insertion Site
- Trial name
- NCT01866501
- Testing
- Intraosseous Vascular Access
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Vidacare Corporation
Vascular Access
Evaluation of Various Methods Used to Identify the Proximal Humerus Intraosseous Vascular Access Site
The purpose of this study is to determine if there is one method of identifying the proximal humerus intraosseous vascular access site that is easier for clinicians to use, out of the 4 methods being evaluated.
- Trial name
- NCT01742780
- Testing
- Intraosseous Vascular Access
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Vidacare Corporation
Intraosseous Vascular Access
Proximal Humerus Site for Anesthesia
This will be a prospective, non-controlled study using healthy adult volunteers as subjects receiving bilateral proximal humerus intraosseous (IO) vascular access to evaluate the insertion technique and IO infusion flow rates.
- Trial name
- NCT01866514
- Testing
- intraosseous vascular access in the proximal humerus, EZ-IO
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Vidacare Corporation
Patients With Intraosseous Vascular Access Requiring Computed Tomography (CT) Exam
Observational Study of CT Dye Administration Through the Intraosseous Vascular Access Route
An observational study to determine the safety and effectiveness of Intraosseous (IO) vascular access for delivery of contrast dye for Computed Tomography (CT) examination.
- Trial name
- NCT01531686
- Testing
- Intraosseous delivery of CT contrast dye
- Where
- 4 sites in United States
- Volunteers
- 8 people
- Sponsor
- Vidacare Corporation
Intraosseous Vascular Access
Healthy Adult Volunteer Study of Intraosseous Infusion Using the Sternum
This study is being done to evaluate intraosseous vascular access through the sternum.
- Trial name
- NCT01853215
- Testing
- T.A.L.O.N. Intraosseous System
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Vidacare Corporation
Complication of Renal Dialysis, End Stage Renal Disease
Trial to Evaluate the Sirolimus-Eluting Collagen Implant on AV Fistula Outcomes
The objective of this study is to evaluate efficacy and safety outcomes following use of the Sirolimus-eluting Collagen Implant (SeCI) in subjects undergoing surgical creation of an AV fistula for vascular access (index…
- Conditions
- Complication of Renal Dialysis, End Stage Renal Disease, End Stage Kidney Disease, ESRD
- Trial name
- ACCESS (NCT02513303)
- Testing
- Sirolimus, AV Fistula Surgery, Sirolimus-eluting Collagen Implant (SeCI)
- Where
- 4 sites in United States
- Volunteers
- 269 people
- Sponsor
- Vascular Therapies, Inc.
Vascular Access Device Complications
Comparing Peripherally Inserted Central Catheters to Long Peripheral Catheters in Pediatrics
Peripherally Inserted Central Catheters (PICCs) are frequently used in hospitalized children who require prolonged vascular access; however, concerns regarding their inappropriate use and contribution to serious complications…
- Trial name
- ComPLET (NCT05346406)
- Testing
- Midline Catheter, Peripherally Inserted Central Catheter
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Medical College of Wisconsin
Vascular Access Complication
Dual-plane Ultrasound Imaging During Vascular Access Procedures
Researchers are evaluating the clinical efficiency of utilization of a dual-plane simultaneous view ultrasound probe (Butterfly iQ+; Butterfly Network, Inc.) during arterial catheter placement in the operating room
- Trial name
- NCT05093699
- Testing
- Butterfly iQ+ ultrasound probe, Ultrasound probe
- Where
- United States
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Catheter Related Complication, Vascular Access Site Management
A Post-Market Clinical Follow Up Study to Evaluate BD PureHub™ Disinfecting Cap Use on Needle-Free Connectors
The study will collect use data of the Becton Dickinson (BD) PureHub™ Disinfecting Cap in combination with needle-free connectors, which are attached to vascular access devices (VAD).
- Conditions
- Catheter Related Complication, Vascular Access Site Management, Disinfecting Cap
- Trial name
- NCT05130762
- Testing
- BD PureHub™ Disinfecting Cap Placements: Attachments/removals
- Where
- 5 sites in Austria, Belgium and 2 more
- Volunteers
- 157 people
- Sponsor
- Becton, Dickinson and Company
IV Catheter-Related Infection or Complication, Vascular Access Complication
Blood Sampling Functionality of Extended Dwell Catheters
The purpose of this study is to compare upper arm versus forearm Extended Dwell Catheter (EDC) placement for blood sampling functionality.
- Conditions
- IV Catheter-Related Infection or Complication, Vascular Access Complication, Peripheral Venous Access
- Trial name
- NCT04409418
- Testing
- Extended dwell catheters
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Corewell Health East
Vascular Diseases, Peripheral Arterial Disease
Post-market, Prospective Evaluation of PHOTO-oxidized Bovine Pericardium in Vascular Surgery
The objective of this post-market clinical follow-up study is to evaluate the clinical outcomes of patients receiving PhotoFix as a patch within a vascular repair or reconstruction procedure.
- Conditions
- Vascular Diseases, Peripheral Arterial Disease, Hemodialysis Access Failure (Disorder), Carotid Artery Diseases
- Trial name
- PHOTO-V (NCT03669042)
- Testing
- PhotoFix
- Where
- 9 sites in United States
- Volunteers
- 94 people
- Sponsor
- Artivion Inc.
Intraosseous Vascular Access
Continuous Intraosseous Vascular Access Over 48 Hours
A prospective study to determine the safety of intraosseous (IO) access for a period up to 48 hours in healthy adult volunteers and volunteers with a history of mild to moderate renal disease and/or controlled diabetes.
- Trial name
- NCT01866475
- Testing
- EZ-IO
- Where
- United States
- Volunteers
- 127 people, healthy volunteers welcome
- Sponsor
- Vidacare Corporation
Renal Failure, End Stage Renal Disease
Safety and Efficacy Assessment of HAV in Patients Needing Vascular Access for Dialysis
This is a Phase 2, prospective, multicenter, open-label, single-arm study of the Human Acellular Vessel (HAV).
- Conditions
- Renal Failure, End Stage Renal Disease, Vascular Access, Hemodialysis
- Trial name
- NCT04135417
- Testing
- HAV
- Where
- 2 sites in Poland
- Volunteers
- 30 people
- Sponsor
- Humacyte, Inc.
End Stage Renal Disease, Vascular Access Patency
Determine the Safety/Efficacy of Ticagrelor for Maintaining Patency of Arterio-Venous Fistulae Created for Hemodialysis
This study is a randomized, placebo-controlled, single blind clinical trial. Seventy patients with ESRD on chronic HD and a functioning AVF will be recruited.
- Trial name
- NCT02335099
- Testing
- ticagrelor
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- University of Virginia
Vascular Access Devices
Peripheral Intravenous Catheter Securement With Tissue Adhesive
This clinical trial will compare survival of peripheral intravenous (IV) catheters for patients with a standard IV site dressing alone to patients with standard IV dressing plus Adhezion Biomedical SecurePortIV Catheter…
- Trial name
- NCT04086693
- Testing
- Standard IV dressing, Standard IV dressing plus a tissue adhesive peripheral IV securement device
- Where
- United States
- Volunteers
- 350 people
- Sponsor
- Corewell Health East
Vascular Access
Comparison of Different Techniques on First Attempt Success in Difficult Vascular Access Patients
The aim of this study is to investigate whether there is any difference between the use of standard techniques, ultrasonography and infra-red light for the success of the first attempt in difficult peripheral vascular access…
- Trial name
- NCT04821362
- Testing
- Ultrasound group, Near Infrared Device Group
- Where
- Turkey (Türkiye)
- Volunteers
- 270 people
- Sponsor
- Ege University
Vascular Access Complication, Ultrasound Therapy; Complications
Superior Venous Access, Midline vs Ultrasound IVs
Obtaining intravenous access (IVA) is the most common procedure performed in the emergency department (ED). Placement of IVA allows for blood work and delivery of intravenous fluids and medications.
- Trial name
- NCT03440944
- Testing
- Ultrasound Guided Peripheral IV Catheter, Midline Catheter
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Boston Medical Center
Vascular Access Complication
AGIR Study: Angio-Seal in Interventional Radiology
Clinical study in patients undergoing any intervention requiring vascular access to the femoral artery. The study compares Angio-Seal™ vs. Manual Compression with regard to control the vascular access.
- Trial name
- AGIR (NCT01911403)
- Testing
- Manual compression, Angio-Seal
- Where
- 2 sites in Portugal, Spain
- Volunteers
- 123 people
- Sponsor
- Abbott Medical Devices