Clinical trials: Vascular Cognitive Impairment no Dementia
Cerebrovascular Disorders
Daphnetin Capsule In the Treatment of VaScular COgnitive Impairment Without Dementia
The purpose of this clinical trial is to understand and evaluate the clinical efficacy and safety of Daphnetin Capsule in patients with vascular cognitive impairment.
- Trial name
- DISCO (NCT06507488)
- Testing
- Daphnetin Capsule
- Where
- China
- Volunteers
- 206 people
- Sponsor
- First People's Hospital of Shenyang
Vascular Cognitive Impairment, Mild Cognitive Impairment
Exercise as a Primer for Brain Stimulation in Vascular Cognitive Impairment No Dementia (VCIND)
People with vascular conditions are at risk of having memory problems, and these memory problems increase the risk for further cognitive decline. Brain stimulation has been used to improve mood and memory.
- Trial name
- EXPRESS-V (NCT05079464)
- Testing
- tDCS, Exercise, Treatment as usual
- Where
- Canada
- Volunteers
- 64 people
- Sponsor
- Sunnybrook Health Sciences Centre
Vascular Cognitive Impairment No Dementia
Language Intervention Training for Cognitive Protection in High-risk Cardio-Cerebrovascular Elderly Population
The global population is aging rapidly, with the number of elderly people with dementia projected to rise sharply, posing significant challenges to quality of life and societal burden.Frequent language switching, such as in…
- Trial name
- NCT06898931
- Testing
- Dialect Interpreting Training
- Volunteers
- 80 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Mild Cognitive Impairment, Coronary Heart Disease
Computerized Cognitive Training in Patients With Coronary Heart Disease and Mild Cognitive Impairment
In this study, a multicentre, double-blind, randomized controlled study based on cognitive training was conducted in patients with coronary heart disease and cognitive impairment but without dementia， to evaluate the…
- Trial name
- COG-T CHD (NCT05735041)
- Testing
- Multi-domain cognitive digital therapy, Basic cognitive therapy
- Where
- 8 sites in China
- Volunteers
- 224 people
- Sponsor
- Beijing Anzhen Hospital
Cognitive Impairment, Stroke
The Efficacy of Gliatiline® on Post-stroke Patients With Vascular Cognitive Impairment no Dementia
To date, there are no approved treatments for vascular cognitive impairment (VCI) and the main therapeutic efforts are aimed at controlling vascular risk factors for countering VCI development or progression.
- Trial name
- GLITTER (NCT01363648)
- Testing
- choline alfoscerate
- Where
- South Korea
- Volunteers
- 222 people
- Sponsor
- Seoul National University Hospital
Vascular Cognitive Impairment no Dementia
Mexidol® Efficacy and Safety in Treatment of VCIND in Older Adults
The primary objective of this study is to evaluate the efficacy of Mexidol® sequential parenteral and oral administration as part of comprehensive therapy in older adults with chronic brain ischemia and vascular cognitive…
- Trial name
- NCT07700615
- Testing
- Mexidol, Standard Therapy
- Where
- 4 sites in Russia
- Volunteers
- 120 people
- Sponsor
- Pharmasoft
Vascular Cognitive Impairment no Dementia
Memory and Antioxidants in Vascular Impairment Trial
This is a 24-week randomized, double-blind, placebo-controlled parallel group design study involving Vascular cognitive impairment-no dementia (VCIND) patients to evaluate the efficacy and safety of oral NAC supplementation…
- Trial name
- NCT03306979
- Testing
- N Acetylcysteine
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- Sunnybrook Health Sciences Centre
Cognitive Impairment
RIVastigmine In Vascular cognitivE Impairment
The study is a 24-week prospective, double blind, randomized, placebo-controlled pilot study of 9 mg / day Rivastigmine in patients with Vascular Cognitive Impairment Not Dementia (CIND) to evaluate efficacy, safety and…
- Trial name
- RIVIVE (NCT00669344)
- Testing
- Exelon (rivastigmine)
- Where
- Singapore
- Volunteers
- 50 people
- Sponsor
- Singapore General Hospital
Vascular Cognitive Impairment no Dementia
Cog-VACCINE: Cognitive Training in Patients With Vascular Cognitive Impairment, no Dementia
This study evaluates the efficacy and mechanism of internet-based cognitive training in patients with subcortical VCIND. Half of participants will receive multi-domain adaptive internet-based training program, while the other…
- Trial name
- Cog-VACCINE (NCT02640716)
- Testing
- multi-domain internet-based adaptive training program
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Beijing Friendship Hospital
Mild Cognitive Impairment, Hypertension
Computerized Cognitive Training to Protect Cognitive Function Among Hypertension Patients
Hypertension is an risk factor for cognitive impairment. The primary objective of this study is to evaluate the efficacy of 12-week computerized cognitive training in people with hypertension and mild cognitive impairment.
- Trial name
- NCT05704270
- Testing
- Multi-domain adaptive cognitive training, Basic cognitive training with no difficulty change
- Where
- 2 sites in China
- Volunteers
- 200 people
- Sponsor
- Beijing Anzhen Hospital
Mild Cognitive Impairment
Efficacy and Safety of Cilostazol in Patients of Vascular Cognitive Impairment-no Dementia (VCIND)
Patients of vascular cognitive impairment-no dementia (VCIND) in one group is prescribed cilostazol,in the other group is prescribed aspirin. Evaluate both of them in cognitive function, MRI and other sides at given time.
- Trial name
- NCT01872858
- Testing
- Aspirin, Cilostazol
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Huashan Hospital
Vascular Cognitive Impairment no Dementia
The Efficacy of Butylphthalide Soft Capsules in Patents With VCIND
Vascular cognitive impairment no dementia (VCIND) is very common among the aged and tends to progress to dementia, but there have been no proper large-scale intervention trials dedicated to it.
- Trial name
- EBSCPVCIND (NCT02993367)
- Testing
- Butylphthalide Soft Capsules
- Where
- China
- Volunteers
- 200 people
- Sponsor
- The Second Hospital of Hebei Medical University