Clinical trials: Vascular Conditions
Coronary Artery Disease, Myocardial Infarction
Comparison Between Moderate-high Interval Exercise and Moderate Continuous Exercise in an Advanced Cardiac Rehabilitation Program
The research will study the differences between interval training and continuous training among cardiac patients in a cardiac rehabilitation facility. The main objectives are: 1. Functional capacity measures (VO2 max). 2.
- Trial name
- NCT02162290
- Testing
- Interval exercise training, Continuous exercise training
- Where
- Israel
- Volunteers
- 84 people
- Sponsor
- Assaf-Harofeh Medical Center
Ischemic Optic Neuropathy, Optic Neuritis
Diffusion Weighted Magnetic Resonance Imaging and the Optic Nerve Neuropathy.
The aim of the project is to create a new, non-invasive and safe protocol for the early diagnosis of various types of optic neuropathies with the use of diffusion magnetic resonance imaging
- Conditions
- Ischemic Optic Neuropathy, Optic Neuritis, Compressive Optic Neuropathy, Traumatic Optic Neuropathy
- Trial name
- NCT05353413
- Testing
- Neuroimaging, VEP - visual evoked potential, Ophthalmology examination.
- Where
- Poland
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Medical University of Bialystok
Infant, Newborn, Infant, Low Birth Weight
Antenatal Phenobarbital to Prevent Neonatal Intracranial Hemorrhage
This large randomized trial tested whether phenobarbital given to a pregnant woman about to deliver a premature infant would prevent brain injuries in their newborns.
- Conditions
- Infant, Newborn, Infant, Low Birth Weight, Infant, Small for Gestational Age, Infant, Premature
- Trial name
- Phenobarbital (NCT00009620)
- Testing
- Phenobarbital, Saline
- Where
- 11 sites in United States
- Volunteers
- 610 people, healthy volunteers welcome
- Sponsor
- NICHD Neonatal Research Network
Ischemic Stroke, Chronic Disease
Whole-life Investigation of Lishui Longevity
1. To establish a standardized, normalized and scientific joint screening and follow-up management system for chronic disease multimorbidity in Lishui City, and early identify common risk factors of major chronic diseases such as…
- Conditions
- Ischemic Stroke, Chronic Disease, Cardiovascular
- Trial name
- WILL (NCT07592962)
- Where
- China
- Volunteers
- 4,500 people
- Sponsor
- The Fifth Affiliated Hospital of Wenzhou Medical University & Lishui Central Hospital
Coronary Artery Disease, Myocardial Ischemia
BIOFLOW-III Sweden Satellite Registry
This registry is a clinical post-market evaluation of the Orsiro LESS in subjects requiring coronary revascularization with Drug Eluting Stents (DES).
- Trial name
- NCT01667003
- Where
- 8 sites in Sweden
- Volunteers
- 406 people
- Sponsor
- Biotronik ApS
Surgical Wound Infection
Prophylactic Negative Wound Pressure Therapy (PICO-7) Following Groin Incisions in Vascular Surgery (PICO-Vasc Study)
Comparison between waterproof sterile dressing OPSITE Post-Op Visible, Smith \& Nephew, UK and PICO-7, Smith \& Nephew, UK in terms of inguinal surgical wound infection and complications after lower limb revascularization.
- Trial name
- PICO-Vasc (NCT04840576)
- Testing
- Regular waterproof sterile dressing., Prophylactic Negative Pressure Dressing
- Where
- Spain
- Volunteers
- 132 people
- Sponsor
- Corporacion Parc Tauli
Critical Ischemia Limb
NOrmoBaric Oxygen Therapy Use In Critical Limb ISchemia
Peripheral arteriopathy disease (PAD) affects 1 million people in France. In its most advanced stage: chronic permanent ischemia also called critical ischemia, the prognosis of patients is burdened with a one-year mortality rate…
- Trial name
- NOBILIS (NCT06238050)
- Testing
- introduction of oxygen therapy or not
- Where
- 3 sites in France
- Volunteers
- 200 people
- Sponsor
- University Hospital, Angers
Stroke, Acute, Stroke, Ischemic
HR-MRI-Directed Tirofiban Therapy for Late-Window Acute Ischemic Stroke (TIAN)
This study aims to address the existing clinical challenges by introducing high-resolution magnetic resonance vessel wall imaging (HR-MRI), an advanced imaging technology, to achieve precise etiological classification in patients…
- Conditions
- Stroke, Acute, Stroke, Ischemic, Cerebral Infarction
- Trial name
- NCT07379190
- Testing
- Tirofiban, dual antiplatelet therapy
- Where
- China
- Volunteers
- 458 people
- Sponsor
- Weifang Medical University
Hemiplegia, Subacute Stroke
Neurodevelopmental Technique Versus Mirror Therapy in Sub-acute Stroke Patients
As neurodevelopmental technique and mirror therapy had different effects on lower limb coordination, functions and ambulation. Both had proven to be helpful in the stroke patients to gain functional independency.
- Conditions
- Hemiplegia, Subacute Stroke, Stroke Rehabilitation
- Trial name
- NDTVSMT (NCT07742020)
- Testing
- Neurodevelopmental Technique (NDT), Mirror Therapy (MT)
- Where
- Pakistan
- Volunteers
- 40 people
- Sponsor
- University of Lahore
Cardiogenic Shock
The Effect of Simultaneous Renal Replacement Therapy on Extracorporeal Membrane Oxygenation Support for Cardiogenic Shock Patients
Extracorporeal membrane oxygenation (ECMO) is a temporary mechanical circulatory support device for cardiogenic shock (CS) patients.
- Trial name
- NCT02870946
- Testing
- Simultaneous RRT, Standard care
- Where
- China
- Volunteers
- 262 people
- Sponsor
- Beijing Anzhen Hospital
Hypertension
A New Translational Tool for Studying the Role of Breathing in Meditation
A recent National Health Interview Survey reported that breathing exercises were the second most common complementary and alternative medicine practice in the United States, following only the use of "natural products." With such…
- Trial name
- NCT01264627
- Testing
- Mindful Breathing (MB) Intervention, Usual Care (UC) Control Condition
- Volunteers
- 99 people
- Sponsor
- University of California, San Francisco
Ischemic Stroke, MCA Infarction
Osmotic Agent Use in Middle Cerebral Artery Stroke
This is a retrospective chart review of patients that were admitted with large MCA stroke to the Fairview system hospitals between December 2017-December 2018.
- Trial name
- OMCAS (NCT04156490)
- Testing
- No intervention is planned, this will be a purely retrospective trial.
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Minnesota
Cardiogenic Shock
CorVad Myocardial Infarction Complicated with Cardiogenic Shock Trial
Cardiogenic shock a serious complication of a heart attack (myocardial infarction). Despite evaluation of several new treatments during the last decade, the mortality in patients with cardiogenic shock still exceeds 50%.
- Trial name
- Corvad AMICS (NCT06886113)
- Testing
- Conventional circulatory support, CorVad
- Where
- China
- Volunteers
- 269 people, healthy volunteers welcome
- Sponsor
- Shenzhen Core Medical Technology CO.,LTD.
Brain Injuries, Traumatic, Coagulopathy
The Influence of Noradrenaline on Coagulation and Fibrinolysis in Severe Isolated Brain Injury
Aim of the study The investigators aim to establish: Whether noradrenaline (NA) infusion has a significant effect on coagulation and fibrinolysis in patients with severe traumatic brain injury (TBI).
- Conditions
- Brain Injuries, Traumatic, Coagulopathy, Coagulation Defect; Acquired, Coagulation Defect; Bleeding
- Trial name
- NCT04515420
- Testing
- noradrenaline
- Volunteers
- 60 people
- Sponsor
- University Medical Centre Ljubljana
Obesity, Insulin Resistance
Effects of Obesity and Intensity of Exercise on Ghrelin Levels
This study is investigating the effect of different intensities of exercise on levels of the hormone, ghrelin. In addition, we will be examining the relationship between any exercise induced changes in ghrelin and insulin…
- Conditions
- Obesity, Insulin Resistance, Cardiovascular Risk Factor
- Trial name
- NCT04581980
- Testing
- Exercise
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Cardiometabolic Syndrome, Obesity and Cardiovascular Risk
Lifestyle Changes, Mushroom Supplementation, and Bupropion to Reduce Adiposity and Cardiometabolic Risk
The increasing prevalence of obesity, its serious health consequences, and the substantial economic burden on healthcare systems underscore a pressing need for effective, long-term prevention strategies that can be implemented in…
- Conditions
- Cardiometabolic Syndrome, Obesity and Cardiovascular Risk, Overweight , Obesity
- Trial name
- NCT07806279
- Testing
- Bupropion 150 mg, Lyophilized powder from edible mushrooms, Lifestyle Management
- Where
- 3 sites in Sweden
- Volunteers
- 250 people
- Sponsor
- Uppsala University
Susac Syndrome
Physiotherapy Approach for Susac Syndrome
Susac's syndrome is a rare autoimmune disorder characterised by a triad of encephalopathy (brain dysfunction), branch retinal artery occlusion (loss of vision) and sensorineural hearing loss.
- Trial name
- NCT06349603
- Where
- Bosnia and Herzegovina
- Volunteers
- 1 people
- Sponsor
- Rehabilitation Centre Zivot
Acute Heart Failure (AHF), Pulmonary Embolism (Diagnosis)
Pulmonary Embolism in Patients With Acute Heart Failure (PEHF Study)
This study focuses on two serious and common medical conditions: heart failure and pulmonary embolism (a blood clot in the lungs).
- Conditions
- Acute Heart Failure (AHF), Pulmonary Embolism (Diagnosis), Venous Thromboembolism
- Trial name
- PEHF (NCT07499661)
- Testing
- Systematic screening for pulmonary embolism in all patients using a guideline-recommended diagnostic algorithm
- Where
- 10 sites in France
- Volunteers
- 740 people
- Sponsor
- University Hospital, Angers
Myocardial Infarction, Cardiac Rehabilitation
Post Myocardial Infarction's Rehabilitation Guided by Heart Rate Variability
Cardiac rehabilitation reduces morbidity and mortality after myocardial infarction (MI) and improve the sympathovagal balance. The autonomic nervous system (ANS) can be explored by the variation of heart rate (HRV).
- Trial name
- HRV REEDUC (NCT03745742)
- Testing
- HRV measurement
- Where
- France
- Volunteers
- 80 people
- Sponsor
- University Hospital, Clermont-Ferrand
Hemorrhage, Obstetric, Uterine Abnormality
Evaluation of the Non-inferiority of Resorbable Gelatin Embolization Compared to Embolization Combined With Endometrial Aspiration for the Management of Hemorrhagic Uterine Vascular Abnormalities Following Premature Termination of Pregnancy
The goal of this clinical trial is to determine the best treatment for patients who experience vaginal bleeding following a premature termination of pregnancy.
- Conditions
- Hemorrhage, Obstetric, Uterine Abnormality, Uterine Artery Embolization, Vaginal Bleeding During Pregnancy
- Trial name
- NIEMBUT (NCT07206342)
- Testing
- embolization therapy, embolization followed by aspiration
- Where
- 4 sites in France
- Volunteers
- 110 people
- Sponsor
- University Hospital, Grenoble
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