Clinical trials: Vascular Dementia
Vascular Dementia
The Clinical Trial of Chinese Herbal Medicine (SaiLuoTong) Capsule
As a traditional Chinese medicine compound, SaiLuoTong capsule is proven to have beneficial effects on learning and memory ability in animal models of vascular dementia (VaD).
- Trial name
- NCT03789760
- Testing
- SaiLuoTong capsule
- Where
- 29 sites in China
- Volunteers
- 493 people
- Sponsor
- Shineway Pharmaceutical Co.,Ltd
Vascular Dementia, Stroke
Cilostazol Verse Asprin for Vascular Dementia in Poststroke Patients With White Matter Lesions
The purpose of this study is to evaluate the efficacy of PDE-3 inhibitor, cilostazol, in prevention and treatment of vascular dementia, in those with brain white matter lesions and vascular risk factors.
- Trial name
- CAVAD (NCT00847860)
- Testing
- Cilostazol, Aspirin
- Where
- 2 sites in China
- Volunteers
- 200 people
- Sponsor
- Peking University First Hospital
Transient Ischemic Attack, Vascular Cognitive Impairment
Reshaping the Path of Vascular Cognitive Impairment (VCI)
The investigators will conduct a proof-of-concept randomized controlled trial study to provide preliminary evidence of efficacy of a resistance exercise training program for maintaining white matter health and improving cognitive…
- Conditions
- Transient Ischemic Attack, Vascular Cognitive Impairment, Subcortical Vascular Dementia
- Trial name
- NCT02669394
- Testing
- Resistance exercise training, Control: stretching and relaxation program
- Where
- Canada
- Volunteers
- 91 people
- Sponsor
- University of British Columbia
Mild Cognitive Impairment, Alzheimer Disease
Predicting the Conversion From Mild Cognitive Impairment to Dementia
Mild cognitive impairment (MCI) is believed to be the early stage of dementia. The investigators assume that some psychological and imaging risks may predict the conversion.
- Conditions
- Mild Cognitive Impairment, Alzheimer Disease, Dementia, Vascular
- Trial name
- PCMCItoD (NCT01823666)
- Where
- China
- Volunteers
- 250 people
- Sponsor
- Dongzhimen Hospital, Beijing
Cerebral Microangiopathy, CADASIL
Impact of tDCS on Cerebral Autoregulation
The aim of the study is to investigate whether there is a polarity-specific influence of tDCS on cerebral vasomotor reactivity monitored by transcranial doppler sonography.
- Conditions
- Cerebral Microangiopathy, CADASIL, Migraine With Aura, ICA Stenosis
- Trial name
- NCT01865604
- Testing
- Anodal tDCS, Cathodal tDCS
- Where
- Germany
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Cognitive Dysfunction, Alzheimer Disease
ALA-enriched Nutrition for Prevention of Cognitive Decline in APOE4 Older Adults
This randomized, double-blind, placebo-controlled pilot trial will evaluate the effects of alpha-linolenic acid (ALA) supplementation on cognitive function, blood-brain barrier integrity, and brain vascular health in older adults…
- Conditions
- Cognitive Dysfunction, Alzheimer Disease, Blood-Brain Barrier, Apolipoprotein E, Deficiency or Defect of
- Trial name
- NCT07392723
- Testing
- Alpha-Linolenic Acid (2.6 g/day)
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Michal Schnaider Beeri, Ph.D.
Alzheimer's Disease, Cardiovascular Risk Factors
Impact of Controlling Vascular Risk Factors on the Progression of Alzheimer's Disease
Three quarters of patients with Alzheimer's disease have at least one vascular risk factor (VRF). Vascular brain lesions are present in most Alzheimer's patients (especially older ones).
- Trial name
- COVARAD (NCT01423396)
- Testing
- optimal care of VRF, standard care
- Where
- 21 sites in France
- Volunteers
- 304 people
- Sponsor
- University Hospital, Lille