Clinical trials: Vascular Disease Risk
Stroke, Osteoporosis
Sarcopenia and Risk of Falls in Patients With Major Chronic Diseases
The objective of this study is to investigate the effects of therapeutic exercise and nutrition intervention for sarcopenia and risk of falls in patients with major chronic diseases.
- Conditions
- Stroke, Osteoporosis, Chronic Kidney Diseases, Cancer
- Trial name
- NCT03798418
- Testing
- elastic band strengthening exercise, diet counseling
- Where
- Taiwan
- Volunteers
- 186 people
- Sponsor
- Changhua Christian Hospital
Atherosclerosis and Blood Flow in Coronary Artery
Geometrical Influences on Atherosclerosis and Blood Flow
The study investigates the use of advanced imaging techniques and computational methods to identify high-risk plaques in coronary arteries.
- Trial name
- NCT07002697
- Where
- Bangladesh
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Bangladesh University of Engineering and Technology
Hypertension, Cardiovascular Risk Factor
Intervention Study on Hypertension Management Combined With Health Promotion at Commune Level
A quasi-experimental study design was chosen to compare the model of hypertension management at commune-level with conventional management for people with high blood pressure in two communes (one for intervention versus one for…
- Conditions
- Hypertension, Cardiovascular Risk Factor, Lifestyle
- Trial name
- NCT01560806
- Testing
- Commune Hypertension Management
- Where
- Vietnam
- Volunteers
- 2,400 people
- Sponsor
- Vietnam National Heart Institute
Stroke
Adipose Tissue Content of Fatty Acids Present in Dairy Fat and Risk of Stroke. The Danish Diet, Cancer and Health Cohort
Background: Although low-fat dairy products are an integral part of a diet recommended for stroke prevention, the role of dairy fat in relation to the risk of stroke is not yet clear.
- Trial name
- NCT03220568
- Testing
- Fatty acids present in adipose tissue samples
- Volunteers
- 57,053 people
- Sponsor
- University of Aarhus
Hypertension
Emerging Biomarkers in Hypertension
First of all to evaluate the relationship between non-conventional biomarkers and essential hypertension; then to evaluate the effects of various anti-hypertensive drugs on blood pressure control and non-conventional biomarkers…
- Trial name
- NCT02064218
- Testing
- Anti-hypertensive drugs
- Where
- Italy
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Pavia
Vascular Calcification, Arteriosclerosis
Study of the Effect of Alendronate on Vascular Calcification and Arterial Stiffness in Chronic Kidney Disease
Cardiovascular disease (CVD) is the commonest cause of mortality in patients with chronic kidney disease (CKD) and end-stage kidney disease (ESKD).
- Trial name
- NCT00395382
- Testing
- Alendronate
- Where
- Australia
- Volunteers
- 50 people
- Sponsor
- Monash University
Pulmonary Embolism
GDF-15 Levels in Risk Stratification in Acute Pulmonary Embolism
Prospective observational study evaluating serum GDF-15 levels in patients with acute pulmonary embolism.
- Trial name
- NCT03672123
- Where
- Poland
- Volunteers
- 270 people
- Sponsor
- Medical University of Warsaw
Venous Thromboembolism (VTE), Chronic Thromboembolic Pulmonary Hypertension
Pulmonary Embolism Registry From Short-Term Emergency to Long-Term Follow-Up and Surveillance
PERSEUS is an academic, investigator-initiated, multicenter observational registry of adults with acute pulmonary embolism (PE), promoted by Azienda Ospedaliero-Universitaria Careggi (Florence, Italy).
- Conditions
- Venous Thromboembolism (VTE), Chronic Thromboembolic Pulmonary Hypertension, Right Ventricular Dysfunction, Pulmonary Embolism (PE)
- Trial name
- PERSEUS (NCT07855679)
- Testing
- Routine clinical care (no study intervention)
- Where
- 16 sites in Italy, Poland and 1 more
- Volunteers
- 5,000 people
- Sponsor
- Azienda Ospedaliero-Universitaria Careggi
Cardiovascular Disease
The Evaluation of Bococizumab (PF-04950615;RN316) in Reducing the Occurrence of Major Cardiovascular Events in High Risk Subjects
This study evaluates the PCSK9 inhibitor, Bococizumab (PF-04950615;RN316), compared to placebo, in reducing the occurrence of major cardiovascular events, including cardiovascular death, myocardial infarction, stroke, and…
- Trial name
- SPIRE-1 (NCT01975376)
- Testing
- bococizumab (PF-04950615)
- Where
- 1,745 sites in United States, Argentina and 34 more
- Volunteers
- 16,784 people
- Sponsor
- Pfizer
Dizziness, Vertigo
Validating a Clinical Decision Support Tool for Stratifying Stroke Risk for Dizziness/Vertigo
This study aims to validate a machine learning model that stratifies the risk of stroke in patients who present to the emergency department with dizziness or vertigo.
- Trial name
- NCT06010550
- Testing
- Magnetic resonance imaging
- Volunteers
- 600 people
- Sponsor
- Chiayi Christian Hospital
Vitamin C Deficiency, Scurvy
Study of Prevalence and Risk Factors of Hypovitaminosis C in Long Term Care Unit
The clinical finding of skin rashes which appear after a vitamin C deficiency in Long Term Care Unit leads us to believe that the institutional diet could predispose to this kind of deficiency.
- Trial name
- Vitamin C (NCT03807791)
- Testing
- Blood sample
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Hospices Civils de Lyon
Myocardial Infarction
Implementation and Assessment of a Life-style Focused Patient Support Application in Myocardial Infarction Patients
The study will assess the efficacy of a web-based application as a complement to traditional exercise-based cardiac rehabilitation for improvement of secondary prevention outcomes in post-myocardial infarction patients, compared…
- Trial name
- NCT03260582
- Testing
- LifePod®
- Where
- 3 sites in Sweden
- Volunteers
- 150 people
- Sponsor
- Lund University
Plasma Cell Leukemia, Recurrent Plasma Cell Myeloma
Combination Chemotherapy and Donor Stem Cell Transplant Followed by Ixazomib Citrate Maintenance Therapy in Treating Patients With Relapsed High-Risk Multiple Myeloma
This phase Ib trial studies the side effects of combination chemotherapy and donor stem cell transplant followed by ixazomib citrate maintenance therapy in treating patients with multiple myeloma that has returned after a period…
- Trial name
- NCT02504359
- Testing
- Allogeneic Hematopoietic Stem Cell Transplantation, Carmustine, Cytarabine
- Where
- 2 sites in United States
- Volunteers
- 11 people
- Sponsor
- OHSU Knight Cancer Institute
Carotid Artery Stenosis
Comparison of Staged Angioplasty and Routine Single-stage Stenting (CAS) in the Treatment of Carotid Artery Stenosis
The purpose of this study is to evaluate the efficacy and safety of staged carotid angioplasty v.s. routine single-stage carotid artery stenting in Chinese patients with carotid artery stenosis at high hyperperfusion risk in…
- Trial name
- STEP (NCT02224209)
- Testing
- Abbott EPD systems (Accunet/Emboshield), a balloon, stent, a balloon, stent
- Where
- China
- Volunteers
- 158 people
- Sponsor
- Beijing Tiantan Hospital
Atherosclerosis, Metabolic Syndrome
Risk Factor Analysis for Coronary Atherosclerosis Measured by MDCT
Coronary MDCT (multi-detector computed tomography) has been useful screening imaging modality for the coronary artery disease. Recently, novel adipokines and hepatokines as well as various inflammatory markers have been known as…
- Trial name
- NCT01589224
- Where
- South Korea
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Korea University
Metabolic Syndrome
Early Vascular Wall Changes by Magnetic Resonance Imaging (MRI) in Metabolic Syndrome Versus Metabolically Normal Pre-Menopausal Women: A Pilot Study
The purpose of this study is to compare the vascular permeability of blood vessel walls (of the carotid artery) in pre-menopausal women who have metabolic syndrome (syndrome of having at least 3/5 following features- increased…
- Trial name
- NCT01068535
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- University of Washington
Carotid Stenosis
Carotid Revascularization and Medical Management for Asymptomatic Carotid Stenosis Trial
Carotid revascularization for primary prevention of stroke (CREST-2) is two independent multicenter, randomized controlled trials of carotid revascularization and intensive medical management versus medical management alone in…
- Trial name
- CREST-2 (NCT02089217)
- Testing
- Carotid endarterectomy (CEA), Carotid Stenting (CAS), Intensive Medical Management - no CEA
- Where
- 167 sites in United States, Australia and 3 more
- Volunteers
- 2,486 people
- Sponsor
- Mayo Clinic
Venous Thromboembolism
A Study in the United Sates That Looks at the Safety and Effectiveness of Pradaxa Pellets in Children Aged 3 Months to Less Than 12 Years Who Need Treatment of a Blood Clot or Who Have Had a Blood Clot and Are at Risk of Developing Another Blood Clot
The main research question of this study is to obtain further safety and effectiveness data on Pradaxa Pellets in children aged 3 months to less than 12 years in routine clinical practice setting.
- Trial name
- NCT05966740
- Where
- 10 sites in United States
- Volunteers
- 5 people
- Sponsor
- Boehringer Ingelheim
Stroke
Stroke Outcome Analysis and Registry in Trinidad and Tobago
This is a prospective observational study to assess risk factors, functional outcomes and mortality at three months for persons admitted to hospital with stroke and transient ischemic attack.
- Trial name
- StART (NCT05256550)
- Where
- Trinidad and Tobago
- Volunteers
- 1,320 people
- Sponsor
- Naveen Seecheran
Type2 Diabetes, Coronary Heart Disease
Konjac-Mannan Improves Glycemia and Other Risk Factors for CHD in T2DM
To examine whether Konjac-mannan fiber improves metabolic control measured by glycemia, lipidemia, and blood pressure in individuals with type-2 diabetes.
- Trial name
- NCT03741660
- Testing
- konjac glucomannan, wheat bran
- Volunteers
- 11 people
- Sponsor
- Unity Health Toronto