Clinical trials: Vascular Dissection
Gastrointestinal Haemorrhage
Purastat® vs Standard Therapy for Haemostasis During Endoscopic Submucosal Dissection
Endoscopic submucosal dissection (ESD) is an endoscopic resection technique used to treat superficial neoplasia in the gastrointestinal tract.
- Trial name
- NCT02833558
- Testing
- PuraStat®, Electrocautery
- Where
- United Kingdom
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- Portsmouth Hospitals NHS Trust
SHOULDER DYSFUNCTION
Virtual Reality For Shoulder Dysfunction Post Neck Dissection Surgeries
The goal of this clinical trial study: is to determine the effect of Virtual reality on pain and function for shoulder dysfunction post neck dissection surgeries.
- Trial name
- NCT06257238
- Testing
- Fully immersive Head-Mounted Display Virtual Reality, Traditional Physical Therapy Program
- Where
- Egypt
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Cairo University
Thyroid Cancer, Thyroidectomy With Central Lymph Node Dissection
Does Parathyroid Autofluorescence Reduces Unintensional Parathyroidectomy During Total Thyroidectomy With Central Lymph Node Compartment Dissection
The aim of the study is to evaluate the effectiveness of autofluorescence in the intraoperative preservation of parathyroids during total thyroidectomy with central lymph node compartment dissection.
- Trial name
- FLUOBCC (NCT04339478)
- Where
- 2 sites in Greece, Jordan
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Aristotle University Of Thessaloniki
Pelvic Organ Prolapse
Retroperitoneal Tunneling Versus Dissection Technique During Sacrocolpopexy
The purpose of this study is to compare operative time, patient reported outcomes, surgical complications, and surgical outcomes between the tunneling versus dissection technique during robotic assisted sacrocolpopexy (RA SCP).
- Trial name
- NCT05969067
- Testing
- Tunneling Technique during RA SCP, Dissection Technique during RA SCP
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- The University of Texas Medical Branch, Galveston
Acute Aortic Syndrome, Aortic Dissection
18F Sodium Fluoride PET/CT in Acute Aortic Syndrome
The purpose of this study is to determine whether Sodium Fluoride imaging (using Positron Emission Tomography-Computed Tomography - PET-CT) is able to predict disease progression in acute aortic syndrome.
- Conditions
- Acute Aortic Syndrome, Aortic Dissection, Penetrating Aortic Ulcer, Intramural Hematoma
- Trial name
- FAASt (NCT03647566)
- Testing
- 18F Sodium Fluoride Positron Emission Tomography / Computed Tomography, CT Aortic Angiogram, Aortic MRI
- Where
- United Kingdom
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- University of Edinburgh
Carpal Tunnel Syndrome, Compare Steroids Versus PRP in Dissection of Median Nerve by Ultrasound
Ultrasound Guided Activated and Non Activated Platelet Rich Plasma Injection Versus Hydro Dissection by Steroids.
PRP represents a promising, nonsurgical option for patients with carpal tunnel syndrome (CTS) with improvement in symptoms compared to placebo, conservative treatment, and local corticosteroid injections at 3-months…
- Trial name
- PRP (NCT06249503)
- Testing
- platelet rich plasma
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Aortic Root Aneurysm, Aortic Root Dissection
Aortic Valve Sparing Root Replacement Versus Bentall
This study was designed to evaluate the hypothesis that the operative and midterm results of valve-sparing aortic root replacement are equivalent to those of the Bentall.
- Trial name
- NCT03604913
- Testing
- Aortic valve sparing operation, Bentall operation
- Where
- Egypt
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Assiut University
Epiretinal Membrane, Retinal Hemorrhage
Robotic Retinal Dissection Device Trial
The purpose of the study is to determine whether use of a robotic system improves the precision and therefore safety of high precision steps in retinal surgery.
- Trial name
- R2D2 (NCT03052881)
- Testing
- Robot assisted surgery
- Where
- United Kingdom
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Aortic Dissection
Potential Diagnostic Biomarkers for Aortic Dissection in the Emergency Department
The goal of this observational study is to determine the utility of desmosine, D-dimer and aggrecan as early diagnostic biomarkers in aortic dissection.
- Trial name
- ADD-ED (NCT06065306)
- Where
- Hong Kong
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Healthy Subject
Effect of Pneumatic Tourniquet on Arm Swelling After Lymph Node Removal
The purpose of the proposed study is to evaluate the acute impact of swelling caused by low-pressure tourniquet use in the setting of ipsilateral prior axillary lymph node dissection and the change in swelling reduction following…
- Trial name
- NCT03584100
- Testing
- Tourniquet 8000
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Stanford University
Spontaneous Coronary Artery Dissection, Healthy
A Study to Analyze the Role of Sympathetic Nervous System in Spontaneous Coronary Artery Dissection
The purpose of this research is to compare sympathetic function (flight or fight system) and arterial health including structure and mechanics of participants with history of spontaneous coronary artery dissection (SCAD) to age…
- Trial name
- NCT05699200
- Testing
- Arterial Tonometry, Echocardiogram, Carotid Ultrasounds
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Aortic Dissection Type B, Intramural Hematoma
CRATOS - Evaluation of Cratos™ Branch Stent Graft System in Treatment of Descending Aorta Lesions
The goal of this prospective, interventional, multicentre, single-arm performance objective study is to evaluate efficacy and safety of Cratos™ Branch Stent Graft System in treatment of lesions (dissection, IMH and PAU in…
- Conditions
- Aortic Dissection Type B, Intramural Hematoma, Penetrating Aortic Ulcer
- Trial name
- NCT05874206
- Testing
- Cratos™ Stent Graft
- Where
- Switzerland
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Shanghai MicroPort Endovascular MedTech（Group）Co., Ltd
Male Infertility
Treatment of Severe Male Infertility - Predictive Factors (Imaging)
Testes of men with non-obstructive azoospermia (NOA) are imaged using MRI to find potential differences depending on the outcome, ie. sperm recovery in consequent microdissection testicular sperm extraction (MD-TESE).
- Trial name
- TESE-MRI (NCT02931721)
- Testing
- MRI
- Where
- 2 sites in Finland
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Turku University Hospital
Fibromuscular Dysplasia of Arteries, Segmental Arterial Mediolysis
Using Ultrasonography, Shear Wave Elastography, Strain Imaging, and 3-D Volume Ultrasonography on Cardiovascular Disease
The researchers are trying to see whether contrast-enhanced ultrasonography, shear wave elastography, strain imaging, and 3-D volume ultrasonography improves arterial wall visualization and identifies arterial elastic properties…
- Conditions
- Fibromuscular Dysplasia of Arteries, Segmental Arterial Mediolysis, Spontaneous Coronary Artery Dissection, Atherosclerosis of Artery
- Trial name
- NCT03335020
- Testing
- Shear Wave Elastography, Pulse Wave Imaging, Contrast-Enhanced Ultrasound
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Mayo Clinic
Thoracic Aortic Aneurysm (TAA), Aortic Dissection
POCUS Screening for TAA in Hypertensive Patients in the ED
The investigators are going to recruit hypertensive patients in the emergency department of Prince of Wales Hospital. Point-of-care ultrasound of the aorta and measurements of the aortic diameter will be obtained.
- Trial name
- NCT06854588
- Testing
- Point-of-care ultrasound
- Where
- 2 sites in Hong Kong
- Volunteers
- 1,483 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Bicuspid Aortic Valve, Thoracic Aortic Aneurysm
Assessment of Risk in Thoracic Aortopathy Using 18F-Sodium Fluoride
Patients with bicuspid aortic valve-related aortopathy are at increased risk of aortic dilatation, dissection and rupture. Currently, risk stratification is largely based on aortic diameter measurements, with those deemed high…
- Conditions
- Bicuspid Aortic Valve, Thoracic Aortic Aneurysm, Aortic Dissection
- Trial name
- AoRTAS (NCT04083118)
- Testing
- clinical evaluation, blood markers, pulse wave analysis, 18F sodium fluoride PET/CT and PET/MRI, Repeat 18F sodium fluoride PET/MRI
- Where
- United Kingdom
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- University of Edinburgh
Myopia, Small-incision Lenticule Extraction (SMILE) Surgery
Factor Analysis of Unintended Initial Dissection of the Posterior Plane
To explore the potential factors for unintended initial dissection of the posterior plane in a large sample retrospective analysis and surgeons of different levels.
- Trial name
- NCT05367154
- Testing
- Small incision lenticule extraction
- Where
- China
- Volunteers
- 3,003 people, healthy volunteers welcome
- Sponsor
- Yifeng Yu
Thyroid Neoplasm, Lymphatic Metastasis
Prophylactic Selective Lateral Neck Dissection in Patients With Papillary Thyroid Carcinoma
The purpose of this study is to prospectively analyze the incidence of occult lateral neck metastasis (LNM) and to elucidate the factors that predict LNM in papillary thyroid carcinoma (PTC) with central neck metastasis (CNM) by…
- Trial name
- NCT01103557
- Testing
- prophylactic selective lateral neck dissection
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Pusan National University Hospital
Endoscopic Submucosal Dissection, Target Controlled Infusion of Propofol
Comparison of the Effects of Target-Controlled Infusion Method and Manual Propofol Administration on Respiratory Function, Recovery, and Electroencephalogram in Endoscopic Submucosal Dissection Cases
Endoscopic submucosal dissection (ESD) has become widely used as a minimally invasive alternative for the resection of early-stage gastrointestinal neoplasms.
- Conditions
- Endoscopic Submucosal Dissection, Target Controlled Infusion of Propofol, Endoscopy Unit, Respiratory Complications
- Trial name
- NCT07305857
- Testing
- manuel propofol and target controlled infusion propofol
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Marmara University Pendik Training and Research Hospital
Invasive Bladder Cancer
HIPEC After Radical Cystectomy for High Risk Bladder Cancer
This is a non-randomized, non-blinded, pilot study administering hyperthermic intraperitoneal chemotherapy with Mitomycin-C in 10 men and women with muscle-invasive urothelial carcinoma of the bladder undergoing radical…
- Trial name
- NCT03514888
- Testing
- HIPEC
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University