Clinical trials: Vascular Function
Stroke, Acute
The Effects of Early Mobilization in Stroke Patients on Functional Status, Psychological Distress, and Quality of Life
This study aims to investigate the effects of an early mobilization intervention in improving functional status, psychological distress, and quality of life in stroke patients.
- Trial name
- NCT05381220
- Testing
- early mobilization
- Where
- 2 sites in Taiwan
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Cognitive Function, Hypertension
Effects of Different Types of Exercise on Cognitive Function in Postmenopausal Hypertensive Women
Brief Summary: The study was conducted in two parts, the first of which was carried out using a cross-sectional design approach to explore the relationship between cognitive function and autonomic function, brain function…
- Trial name
- NCT05898503
- Testing
- Walking exercise + resistance training, Resistance training, Walking exercise
- Where
- China
- Volunteers
- 183 people, healthy volunteers welcome
- Sponsor
- Beijing Sport University
Preeclampsia, Microvascular Function
Prenatal Aspirin and Postpartum Vascular Function
Preeclampsia is a pregnancy disorder affecting ~5-10% of pregnancies in the United States. Women who develop preeclampsia during pregnancy are more likely to develop and die of cardiovascular disease later in life, even if they…
- Trial name
- NCT05653973
- Testing
- Acetylcholine, Endothelin-1
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Anna Stanhewicz, PhD
Peripheral Vascular Diseases
Examining the Impact of Exercise Training on Vascular Dysfunction in Individuals With Mental Health Disorders - Study 1
The purpose of this research study is to examine the role oxidants, substances produced in the blood that can damage blood vessel function, may play in blood vessel function in healthy individuals as well as individuals with…
- Trial name
- NCT04916327
- Testing
- Antioxidant
- Where
- United States
- Volunteers
- 720 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Cardiovascular Injury
Cardiovascular Effects of Exposure to Ozone
The Multicenter Ozone Study in Elderly Subjects will investigate whether short-term exposure of elderly volunteers to ambient levels of ozone in a controlled exposure setting causes acute cardiovascular responses as assessed by…
- Trial name
- MOSES (NCT01487005)
- Where
- 4 sites in United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Health Effects Institute
Heart Disease
The Effect of a Retrofit Particle Trap on the Vascular Effects of Diesel Exhaust Inhalation
The purpose of this study is to determine whether a retrofit particle trap can reduce the adverse vascular responses to diesel exhaust inhalation
- Trial name
- NCT00745446
- Testing
- Forearm Venous Occlusion Plethysmography
- Where
- Sweden
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Edinburgh
Metabolic Syndrome, Obesity
Magnesium and Vascular Stiffness
Observational epidemiologic studies have observed an inverse relationship between daily dietary magnesium intake and blood pressure (BP). Except for BP, magnesium may also beneficially affect other cardiovascular risk markers.
- Trial name
- NCT02235805
- Testing
- Magnesium Citrate
- Where
- Netherlands
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Exercise, Blood Pressure
Effects of Lentil Protein Hydrolysate on Blood Pressure Control, Vascular Function and Exercise Performance
Examining the safety and tolerability of Lentil Protein Hydrolysate in healthy males and females whilst exploring the effects of a dose range on blood pressure control and vascular function and exercise performance
- Conditions
- Exercise, Blood Pressure, Vasodilation, Vascular Function in Healthy Volunteers
- Trial name
- NCT06894875
- Testing
- Lentil protein hydrolysate
- Where
- Australia
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Nuritas Ltd
Healthy
Dietary Salt Intake and Vascular Function
The purpose of this study is to look at the effects of high- and low-salt diets on blood vessel function in healthy subjects.
- Trial name
- NCT00590512
- Testing
- High sodium, Low sodium
- Where
- United States
- Volunteers
- 133 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Early Memory Loss, Mild Cognitive Impairment
NAC-003 P.L.U.S. Program (Progress Through Learning Understanding & Support)
This study will be an observational study in which patients who have been prescribed CerefolinNAC® are invited to participate in surveys regarding their experiences with CerefolinNAC®.
- Conditions
- Early Memory Loss, Mild Cognitive Impairment, Alzheimer's Disease, Vascular Dementia
- Trial name
- NCT01370954
- Testing
- CerefolinNAC®
- Where
- United States
- Volunteers
- 204 people, healthy volunteers welcome
- Sponsor
- Pamlab, Inc.
Alzheimer Disease, Vascular Dementia
Working Memory Functioning in Alzheimer's Disease and Vascular Dementia
The aim of the present study is to investigate potential cognitive mechanisms contributing to working memory impairment in Alzheimer's disease and vascular dementia.
- Conditions
- Alzheimer Disease, Vascular Dementia, Mixed Dementias
- Trial name
- MEMTRAV-COG (NCT06321380)
- Testing
- Complex span task, Clinical neuropsychological assessment, Clinical neurospychological assessement
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Healthy
Trial to Assess the Effects of Different Trans-fatty Acids on Endothelial Function in Humans
The aim of the study is to compare a diet rich in trans fatty acids (TFA) from ruminant sources with a diet rich in TFA from hydrogenated vegetable oils (PHVO) in regard to their effects on cardiovascular risk markers…
- Trial name
- NCT00933322
- Testing
- diet enriched with industrial trans fatty acids, diet enriched with ruminant trans fatty acids, diet without any trans fatty acids
- Where
- Switzerland
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Hypotension Drug-Induced, Cerebral Oxygen Saturation
Effect of Controlled Hypotension on Cerebral Oxygen Saturation
For a successful functional endoscopic sinus surgery (FESS), it is crucial to provide effective controlled hypotension to reduce blood loss and provide a relatively blood-free surgical environment to facilitate surgery.
- Trial name
- NCT02967029
- Testing
- Esmolol Hydrochloride, Remifentanil Hydrochloride
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Peripheral Arterial Disease
Maximal Exercise Capacity, Physical Activity and Respiratory Muscle Strength in Peripheral Artery Disease
The primary aim of the study is to evaluate the maximal and submaximal exercise capacity in patients with peripheral artery disease (PAD).
- Trial name
- NCT03458754
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Gazi University
Metabolic Syndrome, Coronary Heart Disease
Cognition and Exercise Training
The aim of study is to investigate the impact of two different training modalities (high intensity interval training (HIIT) versus moderate intensity continuous exercise training (MICET) on cognitive performance, cerebral…
- Conditions
- Metabolic Syndrome, Coronary Heart Disease, Chronic Heart Failure
- Trial name
- COGNEX-2 (NCT01906957)
- Testing
- high intensity interval training (HIIT), moderate intensity continuous exercise training
- Where
- 2 sites in Canada
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Montreal Heart Institute
Obesity, Prehypertension
Vascular Dysfunction in Human Obesity Hypertension
The purpose of the study is to test the effects of blocking sympathetic nerve activity with a drug called clonidine on blood vessel function and muscle nerve activity in adults who are obese and have high blood pressure.
- Conditions
- Obesity, Prehypertension, Hypertension
- Trial name
- VANISH (NCT01983462)
- Testing
- Clonidine, Hydrochlorothiazide
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Gary L. Pierce
Healthy
Effects of Acute Red Raspberry Consumption on Vascular Function in Healthy Individuals
Accumulating evidence from epidemiological and human intervention studies indicates that the cardiovascular health benefits of diets rich in fruits and vegetables are (in part) related to their (poly)phenol content.
- Trial name
- NCT02734901
- Testing
- 400 g frozen raspberries, 200 g frozen raspberries
- Where
- Germany
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Heinrich-Heine University, Duesseldorf
Smoking
Effect of Electronic Cigarettes on Platelets, Endothelium and Inflammation
The primary purpose of this study is to evaluate the acute effects of electronic cigarette (e-cigarette) smoking on measurable biomarkers of platelet function, vascular endothelial function and inflammation in healthy active…
- Trial name
- NCT02662075
- Testing
- E-cigarette/tobacco Smoking Exposure
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- NYU Langone Health
Chronic Stroke
Combine Effects of Brunnstorm Movement Therapy and LLLT in Chronic Stroke Patient
The primary objective of this study is to determine the combined effects of Brunnstorm movement therapy and low level laser therapy on upper limb function in chronic stroke patient.
- Trial name
- NCT06292481
- Testing
- Brunnstorm movement therapy, Combined Brunnstorm Movement therapy and low level laser therapy
- Where
- Pakistan
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Stroke Patients
Feasibility and Reliability of Using BeCureTM Virtual Reality in Patients With Stroke
The aim of this study is to demonstrate the feasibility and reliability of using virtual reality-based BeCureTM in the assessment of upper extremity motor functions in stroke patients.It is necessary to define the appropriate…
- Trial name
- cros-sectional (NCT06696469)
- Testing
- Feasibility and reliability of using BeCureTM Virtual Reality in the evaluation of upper extremity motor functions in stroke patients
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Ankara University