Clinical trials: Vascular Health
Cardiovascular Disease, Preeclampsia
Heart Health 4 Moms Trial to Reduce CVD Risk After Preeclampsia
This study will compare two arms in a randomized clinical trial of cardiovascular risk prevention in women with a history of preeclampsia.
- Conditions
- Cardiovascular Disease, Preeclampsia, Hypertension, Post-partum Weight Retention
- Trial name
- HH4M (NCT02147626)
- Testing
- Web-based educational and motivational modules, Information and Screening Group
- Where
- United States
- Volunteers
- 151 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Coronary Artery Disease
Improving Adherence to Post PCI Antiplatelet Therapy in Minority Populations
The purpose of this study is to evaluate if the use of a phone based motivational interviewing among minority populations who received a coronary stent can improve adherence to antiplatelet agents from approximately 51% to 66%…
- Trial name
- NCT01651208
- Testing
- Motivational Interviewing (MINT), Mailed DVD
- Where
- United States
- Volunteers
- 452 people
- Sponsor
- University of Miami
Anticoagulants, Atrial Fibrillation
Improving Anticoagulation Control in VISN 1
Over 100,000 VHA patients receive anticoagulants (blood thinners) each year to prevent blood clots (including strokes). Too much anticoagulation increases the risk of serious or even fatal bleeding, and too little anticoagulation…
- Conditions
- Anticoagulants, Atrial Fibrillation, Venous Thromboembolism
- Trial name
- NCT01653405
- Testing
- Multifaceted behavioral intervention
- Where
- United States
- Volunteers
- 1,260,576 people
- Sponsor
- VA Office of Research and Development
Cardiovascular Diseases, Endotoxemia
Cardiometabolic Benefits of Potatoes Mediated Along the Gut-Vessel Axis in Adults With Metabolic Syndrome
This study is focused on assessing potential health benefits of daily consumption of potatoes, specifically its resistant starch content (i.e.
- Conditions
- Cardiovascular Diseases, Endotoxemia, Endothelial Dysfunction, Postprandial Hyperglycemia
- Trial name
- NCT03624569
- Testing
- Bagel, Potato
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Ohio State University
Chronic Disease, Hypertension
Rehabilitation in Primary Care: A Project to Maximize the Health Status of Adults With Chronic Illness
The purpose of the study is to determine whether occupational therapy and physiotherapy delivered in a primary care setting to adults with chronic illness is effective in improving health.
- Conditions
- Chronic Disease, Hypertension, Back Pain, Obesity
- Trial name
- NCT00229957
- Testing
- Occupational therapy, Physiotherapy, Self-management
- Where
- Canada
- Volunteers
- 303 people
- Sponsor
- Hamilton Health Sciences Corporation
Coronary Heart Disease, Susceptibility to, 5, Prediabetic State
Genetic Risk and Health Coaching for Type 2 Diabetes and Coronary Heart Disease
The purpose of this study is to examine whether the use of genetic test information and/or health coaching in patient risk counseling for heart disease and diabetes affect health behaviors and health outcomes in active-duty Air…
- Trial name
- NCT01884545
- Testing
- Health coaching, Genetic risk counseling, Standard risk assessment
- Where
- United States
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Duke University
Medication Adherence, High Blood Pressure
Social Forces to Improve Statin Adherence (Study B)
To assess the effectiveness of social comparison in improving the outcome of statin adherence versus usual care as measured by an electronic pill bottle.
- Conditions
- Medication Adherence, High Blood Pressure, Diabetes
- Trial name
- NCT02148523
- Testing
- Comparison to peers, Adherence feedback, Electronic pill bottle
- Where
- United States
- Volunteers
- 201 people
- Sponsor
- University of Pennsylvania
Hypertension, Dyslipidemias
Communicating Health Information and Improving Coordination With Primary Care
Survivors of childhood cancer are known to be at higher risk of developing premature, serious cardiovascular disease compared with the general population.
- Conditions
- Hypertension, Dyslipidemias, Diabetes, Childhood Cancer
- Trial name
- CHIIP (NCT03104543)
- Testing
- Education, Test results only
- Where
- United States
- Volunteers
- 347 people
- Sponsor
- Fred Hutchinson Cancer Center
Cardiovascular Diseases, Adherence, Medication
Personalized Patient Data and Behavioral Nudges to Improve Adherence to Chronic Cardiovascular Medications
The study plans to learn if sending different text messages, serving as reminders or encouragement, may help patients take their medication more often if they have had trouble keeping up with their medicines.
- Conditions
- Cardiovascular Diseases, Adherence, Medication, Medication Adherence, Diabetes Mellitus
- Trial name
- NCT03973931
- Testing
- Nudge
- Where
- 4 sites in United States
- Volunteers
- 9,501 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Vascular Health of Postmenopausal Women
Acute Effects of Watermelon on Vascular Function and Serum Lycopene
This study aimed to examine the effects of a one-time dose of 100% watermelon juice on circulating lycopene levels and measures of vascular health among a cohort of postmenopausal women.
- Trial name
- NCT03608254
- Testing
- 100% watermelon juice
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- University of Alabama, Tuscaloosa
Diabetic Foot Ulcer, Diabetes Mellitus, Type 2
Effects of a Exercise Program on Health Outcomes in People With Diabetic Foot Ulcers
People with diabetes are at risk for life altering complications, including diabetic foot ulcers. To heal a diabetic foot ulcer, people are often required to refrain from bearing weight on their affected limb for months.
- Trial name
- NCT03002155
- Testing
- EnhanceFitness community exercise program
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of Washington
Acute Coronary Syndrome, Myocardial Infarction
Zyban as an Effective Smoking Cessation Aid for Patients Following an Acute Coronary Syndrome: The ZESCA Trial
Patients who continue to smoke after a heart attack have a 35% increased risk of a recurrent event or death compared with those who quit. Many patients attempt to stop smoking after a heart attack, but relapse rates approach 66%.
- Conditions
- Acute Coronary Syndrome, Myocardial Infarction, Smoking
- Trial name
- ZESCA (NCT00689611)
- Testing
- Bupropion HCl ER
- Where
- 38 sites in United States, Bangladesh and 5 more
- Volunteers
- 392 people
- Sponsor
- Mark Eisenberg
Diabetes, Asthma
Integrated Care (IC) Models for Patient-Centered Outcomes
Multiple chronic conditions (MCC) are widely recognized as the U.S. public health challenge of the 21st century. These physical and behavioral health conditions take a large toll on those living with chronic diseases, including…
- Conditions
- Diabetes, Asthma, Chronic Obstructive Pulmonary Disease, Hypertension
- Trial name
- IC (NCT03451630)
- Testing
- High-Touch, High-Tech, Optimal Discharge Planning
- Where
- United States
- Volunteers
- 1,400 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Cardiovascular Diseases, Coronary Disease
International Study of Comparative Health Effectiveness With Medical and Invasive Approaches (ISCHEMIA)
The purpose of the ISCHEMIA trial is to determine the best management strategy for higher-risk patients with stable ischemic heart disease (SIHD).
- Conditions
- Cardiovascular Diseases, Coronary Disease, Coronary Artery Disease, Heart Diseases
- Trial name
- ISCHEMIA (NCT01471522)
- Testing
- cardiac catheterization, coronary artery bypass graft surgery, percutaneous coronary intervention
- Where
- 320 sites in United States, Argentina and 35 more
- Volunteers
- 5,179 people
- Sponsor
- NYU Langone Health
Dementia, Alzheimer Disease
Efficacy Study of Kinto Care Coaching for Dementia Family Caregivers
The goal of this clinical trial is to evaluate Kinto's Care Coaching intervention for dementia caregivers. The main questions it aims to answer are: Does the intervention help caregivers to address their general caregiving goals…
- Conditions
- Dementia, Alzheimer Disease, Lewy Body Disease, Vascular Dementia
- Trial name
- NCT05916664
- Testing
- Kinto Care Coaching
- Where
- United States
- Volunteers
- 495 people, healthy volunteers welcome
- Sponsor
- Kinto
Coronary Artery Disease, Myocardial Infarction
Impact of a Corrie Cardiac Rehabilitation Program
In this randomized clinical trial, the researchers are investigating whether a multi-component virtual/hybrid cardiac rehabilitation program will improve functional status, cholesterol level, overall cardiovascular health…
- Conditions
- Coronary Artery Disease, Myocardial Infarction, Myocardial Ischemia, Coronary Artery Occlusion
- Trial name
- mTECH-Rehab (NCT05238103)
- Testing
- Corrie Hybrid Cardiac Rehabilitation Program
- Where
- United States
- Volunteers
- 259 people
- Sponsor
- Johns Hopkins University
Diabetes Mellitus, Diabetes Mellitus, Type 2
A Virtual Cardiometabolic Health Program for African Immigrants: The Afro-DPP Program
A pilot study titled "A Virtual Cardiometabolic Health Program for African Immigrants (The Afro-DPP Program) will be conducted to address the cardiometabolic of community-dwelling African immigrants who have multiple…
- Conditions
- Diabetes Mellitus, Diabetes Mellitus, Type 2, PreDiabetes, Hypertension
- Trial name
- NCT05144737
- Testing
- The Diabetes Prevention Program
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Johns Hopkins University
Hypertension
VISN Collaborative for Improving Hypertension Management With ATHENA-HTN
This project is a VA HSR\&D-funded Quality Enhancement Research Initiative (QUERI) project to translate into practice evidence about clinical management of primary hypertension.
- Trial name
- HTN (NCT00374452)
- Testing
- ATHENA-CDS-HTN plus Guideline Link, Guideline Link Only
- Where
- 7 sites in United States
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Myocardial Infarction, Stroke
Women's Health Initiative Strong and Healthy Study
The WHISH trial applies state-of-the science behavioral principles and currently available technologies to deliver a physical activity intervention without face-to-face contact to ~25,000 older U.S. women expected to consent.
- Conditions
- Myocardial Infarction, Stroke, Cardiovascular Mortality, Hip Fractures
- Trial name
- WHISH (NCT02425345)
- Testing
- Physical Activity
- Volunteers
- 49,331 people, healthy volunteers welcome
- Sponsor
- Fred Hutchinson Cancer Center
Dementia, Chronic Disease
Project to Improve Communication About Serious Illness--Hospital Study: Comparative Effectiveness Trial (Trial 2)
The objective of this protocol is to test the effectiveness of a Jumpstart intervention on patient-centered outcomes for patients with chronic illness by ensuring that they receive care that is concordant with their goals over…
- Conditions
- Dementia, Chronic Disease, Neoplasm Metastasis, Lung Neoplasms
- Trial name
- PICSI-H (NCT04283994)
- Testing
- Survey-based Patient/Clinician Jumpstart, EHR-based Clinician Jumpstart
- Where
- 3 sites in United States
- Volunteers
- 756 people
- Sponsor
- University of Washington