Clinical trials: Vascular Occlusive Disease
Coronary Artery Disease, Chronic Kidney Diseases
Intravascular Ultrasound-Guided PCI in Patients With Chronic Kidney Disease
The IVUS-CKD study is a prospective, randomized controlled, multicenter trial to determine whether the intravascular ultrasound (IVUS)-guided percutaneous coronary intervention is superior to the angiography-guidance in chronic…
- Trial name
- IVUS-CKD (NCT06567938)
- Testing
- Percutaneous coronary intervention
- Where
- China
- Volunteers
- 1,528 people
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Coronary Artery Disease
PRV-based Detection of CAD in Comparison to Standard Methods
This is a validation study comparing a pulse wave based algorithm for the detection of coronary artery disease with parameters from coronary angiography, echocardiography and cardiogoniometry.
- Trial name
- PRV-KORO (NCT02404948)
- Testing
- Diagnostic algorithm
- Where
- Germany
- Volunteers
- 156 people, healthy volunteers welcome
- Sponsor
- University Medicine Greifswald
Coronary Artery Disease, Coronary Occlusion
Coronary CTO PCI Using Antegrade Wiring Strategy With a First-choice Gladius Guidewire (Gladius First)
The Gladius First trial is designed as a single-centre, open, prospective, randomized clinical trial aimed to assess the efficiency and safety of coronary chronic total occlusion (CTO) percutaneous coronary intervention (PCI)…
- Conditions
- Coronary Artery Disease, Coronary Occlusion, Percutaneous Coronary Intervention
- Trial name
- Gladius First (NCT04691778)
- Testing
- CTO PCI with the first-choice Gladius guidewire, CTO PCI without the first-choice Gladius guidewire
- Where
- Poland
- Volunteers
- 69 people
- Sponsor
- National Institute of Cardiology, Warsaw, Poland
Arteriosclerosis
Mindfulness-Based Stress Reduction and Myocardial Ischemia
The principal objective of the study is to evaluate the effectiveness of a widely used complementary medicine intervention, mindfulness-based stress reduction (MBSR), in which mindfulness meditation and yoga are the principal…
- Trial name
- NCT00224835
- Testing
- Mindfulness Based Stress Reduction Class, Cardiac Education Class
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- University of Florida
Sinusoidal Obstruction Syndrome
Detection of Sinusoidal Obstruction Syndrome With Ultrasound After Allogeneic HSCT
We would like conduct a real-life study in our center to evaluate the early detection of sinusoidal obstruction syndrome with hepatic ultrasound or elastography before allogeneic hematopoietic stem cell transplantation.
- Trial name
- NCT04141735
- Testing
- ultrasound
- Volunteers
- 114 people
- Sponsor
- Central Hospital, Nancy, France
Coronary Artery Disease, Chronic Total Occlusion
CTO-PCI in Heart Failure Patients
The study investigates wheather CTO-PCI improves survival and heart failure related rehospitalization compared to optimal medical therapy (OMT).
- Conditions
- Coronary Artery Disease, Chronic Total Occlusion, Heart Failure
- Trial name
- CTO-HF (NCT05632653)
- Testing
- CTO-PCI
- Volunteers
- 783 people
- Sponsor
- Universitätsmedizin Mannheim
Peripheral Arterial Disease(PAD)
Korean Vascular Intervention Society Multicenter Registry Study on Outcomes of Endovascular Therapy in Lower Limb Artery Diseases (K-VIS ELLA): (A Retrospective & Prospective Observational Study)
1. Study design: multicenter retrospective and prospective observational study 2. Study Cohort : 1. Retrospective cohort: This cohort retrospectively enrolls patients with lower extremity artery disease who underwent endovascular…
- Trial name
- NCT02748226
- Testing
- endovascular treatment
- Where
- South Korea
- Volunteers
- 12,000 people
- Sponsor
- Yonsei University
Coronary Heart Disease
CTCA Prior to Invasive Angiography in Post-Bypass Patients (BYPASS CTCA 2)
The goal of this clinical trial is to evaluate whether a coronary computed tomography angiography (CTCA)-guided strategy can reduce the risk of death, heart attack, stroke, and hospital admissions in patients experiencing angina…
- Trial name
- NCT07165678
- Testing
- CTCA
- Where
- United Kingdom
- Volunteers
- 1,000 people
- Sponsor
- Queen Mary University of London
Atherosclerotic Cardiovascular Disease
A Retrospective Cohort Study Evaluating Major Adverse Cardiovascular Events and Cardiovascular Outcomes in Adults With Atherosclerotic Cardiovascular Disease Without Prior Ischemic Events (OPTIMUS RISK - Netherlands)
This study will evaluate cardiovascular outcomes among individuals with clinically established atherosclerotic cardiovascular disease (ASCVD) who have not previously experienced a myocardial infarction (MI) or ischemic stroke.
- Trial name
- NCT07905508
- Where
- Netherlands
- Volunteers
- 180,000 people
- Sponsor
- Sanofi
Coronary Artery Disease, Anesthesia
Xenon in Off-pump Coronary Artery Bypass Graft Surgery
Purpose of this study is to test whether xenon application during off-pump-coronary artery bypass (OPCAB)-surgery is safe and feasible.
- Trial name
- NCT01757106
- Testing
- Xenon, sevoflurane
- Where
- Belgium
- Volunteers
- 42 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Coronary Artery Disease, Heart Diseases
Randomization of Single vs Multiple Arterial Grafts
The primary hypothesis of ROMA is that in patients undergoing primary isolated non-emergent coronary artery bypass surgery (CABG), the use of two or more arterial grafts compared to a single arterial graft is associated with a…
- Trial name
- ROMA (NCT03217006)
- Testing
- Single arterial graft, Multiple arterial grafting
- Where
- 59 sites in United States, Austria and 15 more
- Volunteers
- 4,300 people
- Sponsor
- Weill Medical College of Cornell University
Peripheral Artery Disease
Self Selected Exercise Intensity in PAD Patients
Although the benefits of supervised walking training in patients with peripheral arterial disease (PAD) and symptoms of intermittent claudication (IC) are well established, one of the main problems found in this type of protocol…
- Trial name
- NCT04333615
- Testing
- Exercise
- Where
- Brazil
- Volunteers
- 20 people
- Sponsor
- University of Nove de Julho
Moyamoya Disease
Direct Bypass Versus Indirect Bypass in Treatment of Adults Hemorrhagic Moyamoya Disease
The investigators conducted a prospective multi-center study assessing the effect of direct bypass and indrect bypass in treatment of hemorrhagic moyamoya disease.
- Trial name
- NCT02982135
- Testing
- bypass surgery and indrect bypass surgery
- Where
- China
- Volunteers
- 300 people
- Sponsor
- liuxingju
Coronary Artery Disease, Coronary Artery Bypass Grafting
CCTA-Based vs CAG-Based CABG: A Multicenter Pragmatic Non-Inferiority Trial
The goal of this clinical trial is to find out if using a non-invasive heart scan (called coronary computed tomography angiography, or CCTA) to plan coronary artery bypass grafting (CABG) works as well as the standard invasive…
- Conditions
- Coronary Artery Disease, Coronary Artery Bypass Grafting, Coronary Computed Tomography Angiography, Coronary Angiography (CAG)
- Trial name
- CtaCAB (NCT07769008)
- Testing
- CCTA-based CABG, CAG-based CABG
- Where
- China
- Volunteers
- 826 people
- Sponsor
- Ruijin Hospital
Ischaemic Heart Disease
Motion and IntraCoronary Ecg Ischemia Development Study (MICE)
The concept of the "ischemic cascade" is generally accepted hypothesis, according to which whenever ischemia of the myocardium occurs there is a consequence of events, that always occur in a given order - diastolic dysfunction…
- Trial name
- MICE (NCT04061525)
- Testing
- Percutaneous coronary intervention with FFR measurement and intracoronary ECG registration
- Where
- Bulgaria
- Volunteers
- 30 people
- Sponsor
- University National Heart Hospital
Peripheral Vascular Diseases
Understanding the Genetic Basis of Atherosclerosis and Peripheral Arterial Disease
Atherosclerosis, a condition in which fatty deposits build up along the inner walls of arteries, can occur throughout the body. The purpose of this study is to examine the possible genetic differences that may influence where…
- Trial name
- GenePAD (NCT00380185)
- Where
- 2 sites in United States
- Volunteers
- 1,789 people, healthy volunteers welcome
- Sponsor
- Stanford University
Angina Pectoris, Coronary Artery Disease
Effects of Integrated Treatment by Traditional Chinese and Western Medicine in Reducing Cardiovascular Events
Compared with standardized western medical drug therapy, this study is mainly about whether the combination of standardized western medical drug therapy and Chinese medical continued treatment, can further decrease the rate of…
- Conditions
- Angina Pectoris, Coronary Artery Disease, Coronary Disease, Heart Disease
- Trial name
- NCT01715376
- Where
- China
- Volunteers
- 1,042 people, healthy volunteers welcome
- Sponsor
- Changchun University of Chinese Medicine
Macular Edema Secondary to Branch Retinal Vein Occlusion (BRVO)
Study to Show a Superior Benefit in Terms of Reduction of Ranibizumab Injections in Patients Receiving Ranibizumab Plus Laser Photocoagulation Combination Therapy Without Loss of Efficacy and Safety
This is a Phase IV, randomized, open-label, active-controlled, 2-arm, multicenter study. The primary objective was assessed by the difference in the mean number of ranibizumab injections applied up to Month 11 between the 2…
- Trial name
- ZIPANGU (NCT02953938)
- Testing
- Ranibizumab, Grid&Direct short pulse laser photocoagulation
- Where
- 7 sites in Japan
- Volunteers
- 59 people
- Sponsor
- Novartis Pharmaceuticals
Stroke, Atherosclerosis
Comparison of the Improvement and Safety of the Ankle Brachial Arterial Pressure Index of Sarpogrelate and Clopidogrel in Stroke Patients With Decreased Ankle Brachial Arterial Pressure Index and Intermittent Claudication of Lower Limb Vascular Atherosclerosis.
The clinical trial aims to confirm the improvement effect of the ankle brachial index and the safety of sarpogrelate administration compared to clopidogrel in stroke patients with decreased ankle brachial arterial pressure index…
- Trial name
- NCT06424548
- Testing
- Administration of Sarpogrelate, Traditional administration of Clopidogrel
- Volunteers
- 100 people
- Sponsor
- Ewha Womans University Seoul Hospital
Stroke, Ischemic
BEACON-AA: Apixaban With or Without Clopidogrel in Stroke Patients With Atrial Fibrillation and Cerebral Atherosclerosis
This trial aims to compare the safety and efficacy of apixaban alone versus apixaban combined with clopidogrel in patients with acute ischemic stroke associated with non-valvular atrial fibrillation and concomitant symptomatic…
- Conditions
- Stroke, Ischemic, Atrial Fibrillation, Intracrnaial Arterioscelrosis
- Trial name
- NCT07237308
- Testing
- Apixaban, Clopidogrel
- Where
- South Korea
- Volunteers
- 586 people
- Sponsor
- Yonsei University
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.