Clinical trials: Vascular Patients
Refractory Plasma Cell Myeloma
Bortezomib, Lenalidomide, and Dexamethasone in Treating Patients With Multiple Myeloma Undergoing Stem Cell Transplant
This phase II trial studies how well giving bortezomib, lenalidomide, and dexamethasone together works in treating patients with multiple myeloma undergoing stem cell transplant.
- Trial name
- NCT02353468
- Testing
- Bortezomib, Lenalidomide, Dexamethasone
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- University of Colorado, Denver
Pulmonary Fibrosis
Pilot Study of Pirfenidone in Pulmonary Fibrosis With Anti-myeloperoxydase Antibodies
The purpose of this study is to determine wether pirfenidone is safe and effective in the treatment of pulmonary fibrosis with anti-myeloperoxydase (MPO) antibodies or pulmonary fibrosis with anti-MPO associated vasculitis.
- Trial name
- PIRFENIVAS (NCT03385668)
- Testing
- Pirfenidone
- Where
- France
- Volunteers
- 7 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Bladder Carcinoma, Breast Cancer
T Cell Receptor-transduced T Cells Targeting NY-ESO-1 for Treatment of Patients With NY-ESO-1- Expressing Malignancies
Background: Autologous T cells engineered to express a T cell receptor (TCR) targeting NY-ESO-1 will be infused back to patients with NY-ESO-1- expressing malignancies.
- Conditions
- Bladder Carcinoma, Breast Cancer, Esophagus Carcinoma, Lung Cancer
- Trial name
- NCT02457650
- Testing
- Cyclophosphamide, Fludarabine, Anti-NY ESO-1 TCR-transduced T cells
- Where
- China
- Volunteers
- 36 people
- Sponsor
- Shenzhen Second People's Hospital
Pulmonary Embolism
Prognostic Tools in Patients With Acute Pulmonary Thromboembolism.
Acute pulmonary embolism (PE) is a serious disease associated with high mortality rates despite advanced therapeutic options. The treatment options depend on the severity of the disease and the short - term mortality varies…
- Trial name
- NCT04237974
- Testing
- computed tomography pulmonary angiography
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Assiut University
Myocardial Infarction, Heart Arrest
At-Home Automated External Defibrillator (AED) Training Study
The purpose of the research is to determine the best automated external defibrillator (AED) training approach for high-risk patients and their family members with regard to AED skills retention and psychological adjustment.
- Conditions
- Myocardial Infarction, Heart Arrest, Chest Pain, Congestive Heart Failure
- Trial name
- NCT00219674
- Testing
- Group I: Video training, Group II: Video training + enhanced self-efficacy (SE), Group III: In-person training + enhanced SE
- Where
- United States
- Volunteers
- 305 people
- Sponsor
- Public Health - Seattle and King County
Neuropathy, Stroke
Effect of Spasticity on Tibial Nerve Entrapment
Stroke is the most common cause of mortality and is one of the most common causes of morbidity in the world. Polyneuropathies and entrapment neuropathies are known as the complications of stroke
- Trial name
- NCT06092190
- Testing
- EMG
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- October 6 University
Stroke, Transient Ischemic Attack
Smartwatch-Guided Secondary Prevention After Stroke
After a first stroke or transient ischemic attack (TIA), the risk of recurrence is high in the weeks and months following the initial event.
- Trial name
- WATCH-STEP (NCT07640360)
- Testing
- Smartwatch-Guided Secondary Prevention after Stroke
- Where
- France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Brest
Myocardial Infarction
Effects of Intermittent Exercise Training Programs in Patients With Myocardial Infarction
Cardiovascular diseases are a leading cause of death worldwide. According to the World Health Organization (WHO), cardiovascular diseases constitute 1/3 of all causes of death.
- Trial name
- NCT04407624
- Testing
- Intermittent Exercise, Control
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people
- Sponsor
- Dokuz Eylul University
Wound Healing, Patient Comfort
Aquacel Compared to Traditional Post Surgical Wound Dressing in Vascular Surgery Patients
The study is a prospective randomised, controlled study of 136 patients undergoing vascular surgery. Their closed wounds were covered with either aquacel, a hydrofiber dressing, or a traditional gauze dressing.Number of changes…
- Trial name
- NCT00428623
- Testing
- wound dressing
- Where
- Denmark
- Volunteers
- 160 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Soft Tissue Sarcoma
tTF-NGR Randomized Study - STS
In this phase III open label, controlled clinical trial patients with unresectable or metastatic soft-tissue sarcoma after failure of anthracycline-containing first line therapy or with contraindications to these drugs and CD13…
- Trial name
- TRABTRAP (NCT05597917)
- Testing
- Trabectedin, tTF-NGR
- Where
- 9 sites in Germany
- Volunteers
- 126 people
- Sponsor
- Universität Münster
Cystic Fibrosis, Pulmonary Hypertension
Impact of Availability of Showerpatch for Patients With Intravenous Catheters
Venous catheters are necessary for the treatment of many patients. Showering with a venous catheter is often prohibited due to the infection risk when the insertion site becomes wet.
- Conditions
- Cystic Fibrosis, Pulmonary Hypertension, Neoplasms
- Trial name
- ISIC (NCT02324868)
- Testing
- Shower patch IV catheter protection, Conventional IV catheter protection
- Where
- Belgium
- Volunteers
- 18 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Stroke, Quality of Life
EMG Analysis in ABI: Motor Imagery and Action
This study focuses on electromyographic analysis of upper limb muscle activation in stroke survivors during Motor Imagery (MI) and Action Observation (AO) rehabilitation techniques.
- Conditions
- Stroke, Quality of Life, Mirror Movement
- Trial name
- NCT06230718
- Testing
- Motor Imagery (MI), Action Observation (AO)
- Where
- Spain
- Volunteers
- 28 people
- Sponsor
- University of Salamanca
Coronary Heart Disease
Innovation Research of Differentiation and Treatment Methods Based on CHD Phlegm and Blood Stasis Syndrome
Coronary heart disease is still the major cause of death in China. Chinese medicine plays more and more important role in CHD prevention and treatment. Phlegm and blood stasis are its major pathological basis.
- Trial name
- NCT02967718
- Where
- China
- Volunteers
- 13,000 people, healthy volunteers welcome
- Sponsor
- Jingqing Hu
Multiple Myeloma in Relapse
Subcutaneous Talquetamab in Elderly Patients With Multiple Myeloma in Early Relapse
Induction therapy approaches in recent years have evolved, now utilizing triple or quadruple drug regimens in the majority of patients.
- Trial name
- NCT06827860
- Testing
- Talquetamab, Daratumumab
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Larysa Sanchez
Heart Failure, Myocardial Infarction
Impact of Intracoronary Injection of Autologous BMMC for LV Contractility and Remodeling in Patients With STEMI
This is multicentre, randomised open-label, controlled, parallel-group phase III study. Its aim is to demonstrate that a triple intracoronary infusion of autologous bone marrow-derived mononuclear cells in addition to state of…
- Trial name
- RACE-STEMI (NCT02323620)
- Testing
- Intracoronary infusion of BM-MC
- Where
- Poland
- Volunteers
- 200 people
- Sponsor
- American Heart of Poland
Acute Coronary Syndrome, Sleep Disorder
Eszopiclone and Inflammatory Mediators in Patients With Acute Coronary Syndrome
The purpose of the study is to examine the effects of Eszopiclone, a sleep aid, on inflammatory mediators and coagulability in patients with a recent myocardial infarction.
- Trial name
- NCT00822679
- Testing
- Eszopiclone
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- University of Arizona
Coronary Artery Disease, Cardiovascular Diseases
Telenursing in Coronary Artery Disease
The aim of this research is to determine whether follow-up through telehealth consultations can enhance adherence to medication and increase knowledge about heart disease in patients with coronary artery disease (CAD) who have…
- Trial name
- NCT07110779
- Testing
- Telenursing consultation
- Where
- Brazil
- Volunteers
- 150 people
- Sponsor
- Fernanda Maria Alves Lima
Venous Ulcer
Randomized Controlled 8-week Crossover Evaluation of Compression Bandage Systems for Venous Leg Ulcers
The purpose of this study is to evaluate the product performance of a new 2-layer compression bandage for the treatment of venous leg ulcers.
- Trial name
- NCT00301496
- Testing
- Coban 2 Layer Compression System
- Where
- 10 sites in United States, Canada and 1 more
- Volunteers
- 80 people
- Sponsor
- Solventum US LLC
Stroke, Unilateral Spatial Neglect
Therapeutic Serious Game and Rehabilitation of Stroke Patient
The growing field of new technologies offers new perspectives for neurorehabilitation. Serious games are a promising solution in the rehabilitation of cognitive impairments, and they may be useful in the rehabilitation of…
- Trial name
- NCT05661396
- Testing
- Serious game rehabilitation
- Volunteers
- 6 people
- Sponsor
- Hopitaux de Saint-Maurice
Coronary Artery Disease
Pharmacodynamic Effects of Dabigatran in Patients on Dual Antiplatelet Therapy
Dual antiplatelet therapy consisting of aspirin and clopidogrel is the cornerstone of treatment for prevention of atherothrombotic events in patients with coronary artery disease (CAD) undergoing percutaneous coronary…
- Trial name
- NCT01852162
- Testing
- Dabigatran
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- University of Florida
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