Clinical trials: Vascular Patients
Multiple Myeloma
Study of Pomalidomide, Oral Dexamethasone and Very Low-dose Cyclophosphamide in Patients With Refractory Multiple Myeloma Who Have Received Lenalidomide and Bortezomib
Clinical trial with a pharmaceutical specialty in a new combination. Pomalidomide in combination with dexamethasone is indicated in the treatment of adult patients with multiple treatment-resistant or relapsing myeloma who have…
- Trial name
- POCODEX (NCT04243109)
- Testing
- Pomalidomide + Cyclophosphamide + Dexamethasone
- Where
- Spain
- Volunteers
- 6 people
- Sponsor
- Maimónides Biomedical Research Institute of Córdoba
Ischemic Stroke
The Prevalence of a Low Ankle-Brachial Index in Acute Cerebral Ischemia.
Aim of the study is assessment the prevalence of the low ankle-brachial index (ABI) defined less than or equal 0.9 in patients with acute cerebral ischemic event (stroke or transient ischemic attack) and determinate the…
- Trial name
- NCT03948399
- Testing
- Duplex scanning of carotid arteries, ABI measurement
- Where
- Poland
- Volunteers
- 200 people
- Sponsor
- Jan Biziel University Hospital No 2 in Bydgoszcz
Transitional Care Model, Coronary Heart Disease
Medication Adherence and Lipid Management in Patients With Coronary Heart Disease After Percutaneous Coronary Intervention: Application of the Transitional Care Model
Patients with coronary heart disease (CHD) require long-term medication and lifestyle modification following percutaneous coronary intervention (PCI).
- Conditions
- Transitional Care Model, Coronary Heart Disease, Medication Adherence, Self-efficacy
- Trial name
- NCT07346664
- Testing
- routine nursing care group, TCM intervention group
- Where
- China
- Volunteers
- 108 people
- Sponsor
- Qing Wang
Difficult IV Access
Ultrasound-guided Peripheral IV vs. Standard Technique in Difficult Vascular Access Patients by ICU Nurses
This is a randomized controlled single-center study that will be conducted in the intensive care unit. The main objective of this study is to assess the success rate of ultrasound-guided peripheral intravenous cannulation in ICU…
- Trial name
- NCT03745209
- Testing
- Ultrasound
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- Queen's University
Heart Failure, Coronary Artery Disease
Maximal Leg Press Strength Training Study for Coronary Artery Disease Patients
Maximal strength training has been shown to increase muscular strength, muscular volume and work economy. An 8 week maximal leg press training regime will be conducted on cardiac heart failure patients to evaluate whether they…
- Trial name
- NCT00184457
- Testing
- Strength training intervention
- Where
- Norway
- Volunteers
- 12 people
- Sponsor
- Norwegian University of Science and Technology
Multiple Myeloma
PHA-739358 for the Treatment of Multiple Myeloma
The purpose of this study is to determine the antitumor activity of PHA-739358 as single agent IV infusion in adult patients with Multiple Myeloma who have a history of at least 2 previous lines of treatment for the disease.
- Trial name
- NCT00872300
- Testing
- PHA-739358
- Where
- 4 sites in United States, France
- Volunteers
- 7 people
- Sponsor
- Nerviano Medical Sciences
Subacute Stroke, Balance Deficits
Effects of Inspiratory Muscle Training and Abdominal Drawing-In Maneuver on Balance, Gait and Pulmonary Function in Stroke Patients
This study examines how Inspiratory Muscle Training (IMT) combined with the Abdominal Drawing-In Maneuver (ADIM) affects balance, gait, and breathing in stroke patients.
- Trial name
- NCT06838871
- Testing
- Inspiratory Muscle Training (IMT) with Abdominal Drawing-In Maneuver (ADIM) training
- Where
- South Korea
- Volunteers
- 20 people
- Sponsor
- Sahmyook University
Hypertension, Atrial Fibrillation
Renal Sympathetic Denervation in Patients With Hypertension and Paroxysmal Atrial Fibrillation
The purpose of this study is to demonstrate whether renal sympathetic denervation is safe and effective in patients with hypertension and paroxysmal atrial fibrillation.
- Trial name
- RSDforPAF (NCT01814111)
- Testing
- renal sympathetic denervation
- Where
- China
- Volunteers
- 100 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Acute Coronary Syndrome, Recurrent Myocardial Infarction
Primary Prevention With Statin and Incidence of Recurrent MI and Cardiogenic Shock in Post-ACS Patients
This study aims to evaluate the effect of statin for primary prevention, towards lowering the incidence of recurrent myocardial infarction, cardiogenic shock and mortality in ACS patients.
- Conditions
- Acute Coronary Syndrome, Recurrent Myocardial Infarction, Cardiogenic Shock
- Trial name
- NCT03596944
- Testing
- Statin
- Where
- Indonesia
- Volunteers
- 145 people
- Sponsor
- Tarumanagara University
Refractory Multiple Myeloma, Stage I Multiple Myeloma
Melphalan, Peripheral Stem Cell Transplantation, and Interleukin-2 Followed by Interferon Alfa in Treating Patients With Advanced Multiple Myeloma
This phase II trial studies the effectiveness of melphalan, peripheral stem cell transplantation, and interleukin-2 followed by interferon alfa in treating patients who have advanced multiple myeloma (MM).
- Conditions
- Refractory Multiple Myeloma, Stage I Multiple Myeloma, Stage II Multiple Myeloma, Stage III Multiple Myeloma
- Trial name
- NCT00006244
- Testing
- melphalan, recombinant interferon alfa, aldesleukin
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Fred Hutchinson Cancer Center
Stroke, Hypertension
Controlled Education Of Patients After Stroke
The main objective of the study is to compare the benefit of optimised follow-up by nursing personnel from the vascular neurology department, including therapeutic follow-up and an educational program directed to the patient and…
- Trial name
- CEOPS (NCT02132364)
- Testing
- optimised follow-up
- Where
- 17 sites in France
- Volunteers
- 290 people
- Sponsor
- University Hospital, Lille
Multiple Myeloma
A Plant-Based Whole-Foods Meal Delivery Service for Patients With Multiple Myeloma Undergoing Autologous Hematopoietic Cell Transplant
This clinical trial evaluates the impact of a plant-based whole-foods delivery service on the microbiome in patients with multiple myeloma undergoing an autologous hematopoietic cell transplant.
- Trial name
- NCT06559709
- Testing
- Biospecimen Collection, Dietary Intervention, Medical Chart Review
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Fred Hutchinson Cancer Center
Venous Thromboembolism
Individual Dose Adjustment of Low-molecular-weight-heparin by Thromodynamics Test.
The aim of this study is to evaluate the efficacy and safety of individual dose adjustment of low molecular weight heparin (LMWH) based on the results of the thrombodynamics test (TD) in patients at extremely high risk of…
- Trial name
- IDAHeT (NCT04710732)
- Testing
- Standard Enoxaparin 40 mg once-daily before randomization, Standard Enoxaparin 40 mg once-daily after randomization, Escalated Enoxaparin 30 mg twice-daily after randomization
- Where
- Russia
- Volunteers
- 9 people
- Sponsor
- Pirogov Russian National Research Medical University
Peripheral Arterial Disease
Influence of Rivaroxaban for Intermittent Claudication and Exercise Tolerance in Patients With Symptomatic PAD
The aim of the conducted research is to evaluate the protective effect of rivaroxaban (trade name of the Xarelto medicinal product), administered together with acetylsalicylic acid (ASA), in comparison with the effectiveness of…
- Trial name
- PAD_RIV_CLI (NCT04305028)
- Testing
- Rivaroxaban, Aspirin
- Volunteers
- 100 people
- Sponsor
- Poznan University of Medical Sciences
Cervical Artery Dissection, Carotid Artery Dissection
To Determine the Feasibility of a Clinical Trial Comparing Anticoagulants Versus Antiplatelets in the Acute Treatment of Patients With Cervical Artery Dissection
This is a feasibility study to determine if a sufficient number of patients can be recruited throughout the United Kingdom and whether sufficient endpoints can be generated for a full scale therapeutic trial of anticoagulants…
- Conditions
- Cervical Artery Dissection, Carotid Artery Dissection, Vertebral Artery Dissection, Stroke
- Trial name
- CADISS (NCT00238667)
- Testing
- Antiplatelet (Aspirin, Dipyridamole, clopidogrel), Anticoagulant (Unfractionated Heparin, LMW Heparin, Warfarin)
- Where
- United Kingdom
- Volunteers
- 250 people
- Sponsor
- St George's, University of London
Pulmonary Hypertension
Safety and Efficacy of Sitaxsentan in the Treatment of Pulmonary Arterial Hypertension
This is a clinical research study designed to evaluate an investigational new medication called sitaxsentan for the treatment of pulmonary arterial hypertension (patients with NYHA functional class II, III or IV).
- Trial name
- NCT00034307
- Testing
- sitaxsentan sodium
- Where
- 26 sites in United States, Canada
- Volunteers
- 180 people
- Sponsor
- ICOS-Texas Biotechnology
Multiple Myeloma
Revlimid And Prednisone Followed By Revlimid, Melphalan And Prednisone In Multiple Myeloma Patients
This study will determine whether the association of Revlimid and Prednisone (RP) as induction treatment followed by Revlimid, Melphalan and Prednisone (MPR) as consolidation treatment is safe and induce a significant rate of PR…
- Trial name
- RP_MPR (NCT01160107)
- Testing
- RP followed by MPR
- Volunteers
- 46 people
- Sponsor
- Fondazione EMN Italy Onlus
Multiple Myeloma
Japanese Study of BMS-901608 (Elotuzumab) in Combination With Lenalidomide and Low Dose Dexamethasone
The purpose of this study is to assess the safety and tolerability of Elotuzumab when given in combination with Lenalidomide and low-dose Dexamethasone in subjects with relapsed or refractory multiple myeloma (MM) in Japan.
- Trial name
- NCT01241292
- Testing
- BMS-901608 (Elotuzumab) 10 mg, BMS-901608 (Elotuzumab) 20 mg
- Where
- 3 sites in Japan
- Volunteers
- 7 people
- Sponsor
- Bristol-Myers Squibb
Ischemic Optic Neuropathy
ENDOTHELION Study Group: Effect of Bosentan in NAION Patients
Acute ischemic optic neuropathy are the second leading cause of optic neuropathy after glaucoma in the population aged over 50 years.
- Trial name
- ENDOTHELION (NCT02377271)
- Testing
- bosentan
- Where
- 7 sites in France
- Volunteers
- 86 people
- Sponsor
- University Hospital, Grenoble
Vein of Galen Malformation
Vein of Galen Aneurysm
1. Foundations of the clinical research project: Vein of Galen vascular malformations are a group of rare cerebral vascular malformations with complex anatomy and severe clinical consequences.
- Trial name
- NCT06595264
- Testing
- embolization therapy
- Where
- Belgium
- Volunteers
- 19 people
- Sponsor
- Erasme University Hospital
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