Clinical trials: Vascular Remodeling
ST Elevation Myocardial Infarction, Ventricular Remodeling
Impact of Ischemic Post-conditioning
Study will investigate \& compare the left ventricular remodeling \& systolic function between two groups of ST-elevation myocardial infarction undergoing primary per-cutaneous coronary intervention applying ischemic…
- Conditions
- ST Elevation Myocardial Infarction, Ventricular Remodeling, Ventricular Dysfunction, Ischemic Reperfusion Injury
- Trial name
- NCT04068116
- Testing
- Primary per-cutaneous coronary intervention
- Volunteers
- 100 people
- Sponsor
- Assiut University
Myocardial Infarction, Death
Acute Myocardial Infarction Quality Assurance Project
Cohort study aimed at evaluating the incidence of left ventricular (LV) dysfunction after myocardial infraction (MI) and assessing the prognostic utility of change in ejection fraction (EF) over the initial 12 months after MI.
- Conditions
- Myocardial Infarction, Death, Heart Failure
- Trial name
- AMIQA (NCT02399891)
- Testing
- Quality Assurance Implementation, Standard of Care
- Where
- Canada
- Volunteers
- 6,000 people
- Sponsor
- Dr. Derek Exner
ST-segment Elevation Myocardial Infarction, Left Ventricular Remodeling
The Effect of Glucocorticoid Therapy on Left Ventricular Remodelling in Acute Myocardial Infarction (RECONSIDER)
Introduction: In the setting of acute ST-segment elevation myocardial infarction (STEMI) coronary wedge pressure (CWP) emerges as a new marker for the advanced form of pre-procedural microvascular obstruction (MVO), which is…
- Trial name
- RECONSIDER (NCT03371784)
- Testing
- Hydrocortisone
- Where
- Romania
- Volunteers
- 77 people
- Sponsor
- Iuliu Hatieganu University of Medicine and Pharmacy
Myocardial Infarction
BELIEVE Study: Nesiritide and Post Myocardial Infarction Left Ventricular Modeling
This study is being done to determine the effects (good and bad) of intravenous infusion of a human brain natriuretic peptide (BNP), Natrecor (nesiritide), a hormone produced by the heart in persons who have just suffered a heart…
- Trial name
- NCT00252213
- Testing
- Human BNP
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Myocardial Infarction, Oxidative Stress
Tight Glycemic Control Increases Cardiac Stem Cells During Acute Myocardial Infarction
Objectives. The investigators analysed the effects of tight glycemic control in regenerative potential of the myocardium during acute myocardial infarction (AMI). Background.
- Conditions
- Myocardial Infarction, Oxidative Stress, Glycemic Control
- Trial name
- NCT00863629
- Testing
- Insulin
- Where
- Italy
- Volunteers
- 65 people
- Sponsor
- University of Campania Luigi Vanvitelli
Thyroid, Cardiac Remodeling, Ventricular
Effect of Thyroid Hormone on Post-Myocardial Infarction Remodeling and Prognosis in STEMI Patients
This study aims to determine whether thyroid hormone levels are predictive of cardiac remodeling following myocardial infarction and the prognosis in patients with STEMI receiving primary percutaneous coronary intervention.
- Conditions
- Thyroid, Cardiac Remodeling, Ventricular, STEMI
- Trial name
- ThyREST (NCT03933358)
- Testing
- Thyroid hormone levels
- Where
- China
- Volunteers
- 250 people
- Sponsor
- Beijing Friendship Hospital
Myocardial Infarct, Remodeling, Left Ventricle
Heart Attack Blood Oxygen Therapy Trial
'Heart attack', known as acute ST-segment elevation myocardial infarction, is a leading cause of heart failure and death. A lack of blood and oxygen damages the heart muscle potentially causing heart failure and premature death.
- Trial name
- SSO2 Radial MI (NCT06662890)
- Testing
- Supersaturated oxygen
- Where
- United Kingdom
- Volunteers
- 56 people
- Sponsor
- NHS National Waiting Times Centre Board
Hypertension, Ischemic Heart Disease
A Morbidity-Mortality and Remodeling Study With Valsartan
The JIKEI HEART Study has been designed to investigate whether concomitant treatment with valsartan, an angiotensin II receptor blocker (ARB), in addition to conventional treatment, will improve the prognosis of 3000 Japanese…
- Conditions
- Hypertension, Ischemic Heart Disease, Congestive Heart Failure
- Trial name
- NCT00133328
- Testing
- valsartan
- Where
- Japan
- Volunteers
- 3,000 people
- Sponsor
- Jikei University School of Medicine
STEMI
ReModeling in ST-elevation myocARrdial Infarction: a Comparison of Left VEntricuLar Functions in Long-term Follow-up Among STEMI Patients
Patients diagnosed with STEMI who underwent pPCI were included in this study. The investigators collected comprehensive data on each patient's status, including laboratory findings such as NT-proBNP, troponin levels, and…
- Trial name
- MARVEL (NCT07041840)
- Where
- Italy
- Volunteers
- 80 people
- Sponsor
- University of Pisa
ST Elevation Myocardial Infarction, Remodeling, Left Ventricle
Predictors of Adverse Left Ventricular Remodeling and Final Infarct Size After Primary Percutaneous Coronary Intervention for ST Elevation Myocardial Infarction: A Strain Analysis Study Using Echocardiography and Feature Tracking Cardiac Magnetic Resonance
ST-segment elevation myocardial infarction (STEMI) is one of the most important causes of death and disability around the world.
- Trial name
- NCT04773652
- Testing
- speckle tracking echo
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Cairo University
Arterial Calcification, Kidney Failure
Vascular Calcifications in Kidney Transplant Recipient
Kidney transplant candidates undergo extensive diagnostic evaluation aimed at assessing their cardiovascular (CV) risk, which remains the leading cause of disability and death in this patient population.
- Conditions
- Arterial Calcification, Kidney Failure, Kidney Transplant; Complications
- Trial name
- NCT05697458
- Testing
- computerized tomography scanning
- Where
- Croatia
- Volunteers
- 70 people
- Sponsor
- Clinical Hospital Center Rijeka
Coronary Artery Disease, Coronary Stenosis
The PICCOLETO XIII REVEAL-DCB Cohort A Study
To characterize, using paired coronary computed tomography angiography (CCTA), longitudinal changes in coronary atherosclerotic plaque, lumen dimensions, and vessel remodeling between baseline and mid-term follow-up in de novo…
- Conditions
- Coronary Artery Disease, Coronary Stenosis, Coronary Restenosis, Coronary Atherosclerosis
- Trial name
- REVEAL-DCB-A (NCT07868523)
- Volunteers
- 200 people
- Sponsor
- Fondazione Ricerca e Innovazione Cardiovascolare ETS
Chronic Obstructive Pulmonary Disease
Hydrogen Sulfide and Pulmonary Vascular Remodeling on HRCT in Patients With COPD
HRCT was used to evaluate pulmonary vascular remodeling in COPD. The role of H2S in pulmonary vascular remodeling in COPD was analyzed, in order to provide a basis for seeking new therapeutic targets.
- Trial name
- NCT04952883
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Peking University Third Hospital
Anomalous Coronary Artery Origin, Anomalous Coronary Artery Arising from the Opposite Sinus
New Patient-specific Functional Assessment of the Anomalous Aortic Origin of Coronary Arteries.
Anomalous Aortic Origin of the Coronary Arteries (AAOCA) is a rare congenital disease that may cause sudden death in young subjects.
- Conditions
- Anomalous Coronary Artery Origin, Anomalous Coronary Artery Arising from the Opposite Sinus, Anomalous Coronary Artery Course, Anomalous Coronary Artery with Aortic Origin and Course Between the Great Arteries
- Trial name
- NECESSARY (NCT05159791)
- Testing
- Invasive coronary blood flow assessment and simulations and fluid dynamic patient specific simulation
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- IRCCS Policlinico S. Donato