Clinical trials: Vascular Surgical Procedures
Renal Replacement Therapy, Renal Dialysis
A Clinical Trial of IntensiVE Dialysis
This study will assess clinical outcomes of extended weekly hours of haemodialysis (>= 24 hours per week) compared with standard hours of haemodialysis (<=18 hours/week) in people with ESKD.
- Conditions
- Renal Replacement Therapy, Renal Dialysis, End Stage Kidney Disease, End Stage Renal Disease
- Trial name
- ACTIVE (NCT00649298)
- Testing
- haemodialysis
- Where
- 40 sites in Australia, Canada and 2 more
- Volunteers
- 200 people
- Sponsor
- The George Institute
Diseased or Occluded Blood Vessels, Arteriovenous Shunting for Blood Access
LeMaitre LifeSpan® ePTFE Vascular Graft Retrospective Registry
This is a post-market, single-arm, retrospective registry. The investigator or its representative will identify eligible patients through a medical record search.
- Trial name
- NCT04620889
- Testing
- AV Access, PVP
- Where
- Germany
- Volunteers
- 153 people
- Sponsor
- LeMaitre Vascular
Vascular Surgical Procedure, Peripheral Arterial Disease(PAD)
Lymphatic Injury Visualization in Vascular Surgery
This study aims to assess a simple intervention: Visualization of lymphatic injury + treatment (in case of detection). This will generate data on the incidence of intraoperative lymphatic injury and the effect of treatment.
- Conditions
- Vascular Surgical Procedure, Peripheral Arterial Disease(PAD), Acute Ischemia, Hemmorhage
- Trial name
- LymphFistula-P (NCT07499206)
- Testing
- Visualization of lymphatic injury and treatment of injury (in case of detection)
- Where
- Switzerland
- Volunteers
- 60 people
- Sponsor
- University Hospital, Basel, Switzerland
Massive Transfusion, Trauma
Australian and New Zealand Massive Transfusion Registry
Severe and un-stopped blood loss can occur for a number of different reasons including after a serious injury, delivery of a baby and following other medical and surgical emergencies.
- Conditions
- Massive Transfusion, Trauma, Cardiothoracic Surgery, Gastrointestinal Bleeding
- Trial name
- ANZ-MTR (NCT02863250)
- Where
- Australia
- Volunteers
- 50,000 people
- Sponsor
- Monash University
Bleeding Active
Effectiveness and Safety of CELSTAT for Hemostasis in Intraoperative Tissue Bleeding
The study is to evaluate the effectiveness and safety of CELSTAT vs active control.
- Trial name
- CELSTAT (NCT02640235)
- Testing
- CELSTAT, Surgicel Original
- Where
- 25 sites in United States, Czechia and 2 more
- Volunteers
- 260 people
- Sponsor
- Baxter Healthcare Corporation
Complication,Postoperative
Heparin Alone vs. Heparin-Aspirin Combo in Free Flap Survival
This randomized clinical trial aims to compare the effectiveness of heparin alone versus combination therapy of Heparin- Aspirin in improving free flap survival in patients undergoing reconstructive surgery.
- Trial name
- NCT06512233
- Testing
- LMW Heparin 5000 U/ML-Aspirin 75 MG, LMW Heparin 5000 U/ML
- Where
- Pakistan
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Myocardial Injury
Anti-oxidant Therapy and Postoperative Cardiac Events (ACE) Trial, Preoperative Intervention in Vascular Surgery
N Terminal (NT)-Pro b-type natriuretic peptide (BNP) levels provide incremental value in perioperative risk assessment prior to major non-cardiac surgery.
- Trial name
- ACE (NCT03956017)
- Testing
- Ubiquinone
- Where
- United States
- Volunteers
- 341 people, healthy volunteers welcome
- Sponsor
- Minneapolis Veterans Affairs Medical Center
Quality of Life
Anesthesia Geriatric Evaluation and Quality of Life After Peripheral Vascular Surgery
A prospective observational cohort study to assess the predictive value of preoperative frailty on postoperative quality of life in peripheral vascular surgery patients.
- Trial name
- AGE-VASC (NCT02820831)
- Where
- Netherlands
- Volunteers
- 88 people
- Sponsor
- St. Antonius Hospital
Incisional Hernia of Midline of Abdomen, Surgical Wound
Onlay Mesh in Abdominal Aortic Aneurysm Repair.
The aim of the study was to compare the incidence of IH after abdominal aortic aneurysm (AAA) open repair according to the abdominal wall closure technique used.
- Trial name
- NCT07416422
- Testing
- Abdominal Ultrasound or computed tomography
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- Hospital Universitario Ramon y Cajal
Intracerebral Hemorrhage, Surgery
Comparison Between Stereotactic Aspiration and Intra-endoscopic Surgery to Treat Intracerebral Hemorrhage
Views for surgery method selection of intracerebral hemorrhage are still controversial. Since the application of neuroendoscopic technique in intraventricular hemorrhage was confirmed effective and safe, some investigators have…
- Trial name
- EndoSurofICH (NCT02515903)
- Testing
- Intra-endoscopic surgery
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Nanfang Hospital, Southern Medical University
Perioperative Bleeding
Platelet Function Testing Help and Intraoperative Bleeding Risk for Patients Who Are on Plavix Prior to Surgery
A large number of patients are currently on Antiplatelet inhibition using aspirin or Plavix therapy (A Thieno pyridine - ADP mediated platelet inhibitor).
- Trial name
- NCT00653900
- Where
- United States
- Sponsor
- Cedars-Sinai Medical Center
Venous Thromboembolism
Efficacy of Sodium Heparin for Prophylaxis of Venous Thromboembolism in Surgical Patients
The aim of this study is to verify, through clinical examination and doppler, the non-inferiority of the drug test (heparin sodium 5.000UI/0.25 mL - HIPOLABOR) in relation to the drug compared (heparin sodium 5.000USP/mL - APP)…
- Trial name
- NCT00934167
- Testing
- heparin sodium - Hipolabor, Heparin sodium - APP
- Where
- Brazil
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Azidus Brasil
Idiopathic Toe Walking, Cerebral Palsy
The Effect of Targeting the Plantaris Muscle-tendon in Surgical Correction of Ankle Equinus in Children
Tight ankle muscles can produce ankle equinus (limited ability to pull the foot upward) and occur often in children, significantly impacting their ability to walk.
- Conditions
- Idiopathic Toe Walking, Cerebral Palsy, Hereditary Spastic Paraparesis, Traumatic Brain Injury
- Trial name
- Plantaris Sx (NCT07090057)
- Testing
- Tendoachilles (TA) lengthening or gastrocnemius (GN) recession, then Plantaris tenotomy, Plantaris tenotomy, then Tendoachilles (TA) lengthening or gastrocnemius (GN) recession
- Where
- Canada
- Volunteers
- 42 people
- Sponsor
- University of Alberta
Pressure Ulcers, Venous Ulcers
Prospective PuraPly™ AM Case Series Study
The PuraPly AM case series is a prospective, observational study for patients who have received PuraPly AM which consists of a collagen sheet coated with polyhexamethylene biguanide hydrochloride (PHMB) and is intended for the…
- Conditions
- Pressure Ulcers, Venous Ulcers, Diabetic Ulcers, Surgical Wounds
- Trial name
- NCT03070925
- Testing
- PuraPly™ Antimicrobial Wound Matrix
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- Organogenesis
Hepatitis C
WEUSKOP5410: Observational Study in ENABLE Clinical Trials
Hepatitis C Virus (HCV) is a leading cause of chronic liver disease (CLD) worldwide. Current mainstay of treatment is combination therapy with pegylated interferon and ribavarin.
- Trial name
- NCT01458080
- Testing
- eltrombopag
- Volunteers
- 1 people
- Sponsor
- GlaxoSmithKline
Leg Injuries, Winter Sport Resorts
Evaluation of the Prevention of Thromboembolic Disease in Patients With a Lower Limb Trauma, Non Surgical, in Winter Sports Resort
The purpose of this study is to evaluate the impact of thromboembolic diseases and heparin complications in patients with a lower limb trauma supported by physicians of mountain.
- Conditions
- Leg Injuries, Winter Sport Resorts, Outpatients
- Trial name
- M2M-Thrombose (NCT01303523)
- Where
- 28 sites in France
- Volunteers
- 1,627 people
- Sponsor
- Floralis
Vascular Diseases, Peripheral Vascular Disease
Topical Gentamicin and Vancomycin for Vascular Surgical Site Infection Prophylaxis
Many patients who undergo vascular surgery to improve the blood flow to their legs are at risk of developing an infection in the surgical site and are then at risk of serious complications such as hospital readmission, failure of…
- Conditions
- Vascular Diseases, Peripheral Vascular Disease, Surgical Site Infection, Bypass Complication
- Trial name
- NCT04238923
- Testing
- Topical vancomycin paste (1g vancomycin powder + 4mL sterile saline) and Collatamp G gentamicin-eluting sponge (Azralez Pharmaceuticals; 2.0mg gentamicin sulphate/cm2 to cover wound)
- Volunteers
- 356 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Vascular Surgical Procedures
Comparison Trial Between Elastic-compressive Stockings at 21 Versus 32 mmHg
Endovascular thermal ablation is currently considered as the best procedure for treating varicose veins thanks to its mini-invasiveness and the lowest rate of incidence of complications.
- Trial name
- CALESSE (NCT05766579)
- Testing
- Elastic-compressive stockings
- Where
- Italy
- Volunteers
- 64 people
- Sponsor
- IRCCS Policlinico S. Donato
Intraspinal Tumor, Juxtamedullary Tumor
Multicenter Trial on Surgical Outcome and Quality of Life in Juxta-medullary Tumors
Primary objectives: Primary objectives are to assess and define benchmarks of the surgical outcome in the form of extent of resection, functionality, and quality of life after resection of juxta medullary tumors Secondary…
- Trial name
- EURJMT (NCT07056023)
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- University Hospital Muenster
Thoracic Outlet Syndrome
DEFILE-QoL5 - Evaluation of the Long-term Surgical Management of the Thoraco-brachial Displacement Syndrome
The study concerns patients hospitalized in vascular and thoracic surgery in 2016 at the University Hospital of Angers for the management of a thoraco-brachial outlet syndrome.
- Trial name
- DEFILE-QoL5 (NCT06036888)
- Testing
- questionaries completion
- Where
- France
- Volunteers
- 53 people
- Sponsor
- University Hospital, Angers