Clinical trials: Vascular Surgical Procedures
Thrombosis, Venous
A Study to Evaluate the Efficacy and Safety of Fondaparinux for the Prevention of Venous Blood Clots in Patients With a Plaster Cast or Other Type of Immobilization for a Below-knee Injury Not Needing Surgery
The purpose of this study is to evaluate the efficacy and safety of fondaparinux in comparison with a heparin (nadroparin) in preventing deep vein thrombosis (blood clots in the leg veins), whether symptomatic or detected by…
- Trial name
- FONDACAST (NCT00843492)
- Testing
- Fondaparinux sodium, Nadroparin
- Where
- 122 sites in France, Germany and 4 more
- Volunteers
- 1,351 people
- Sponsor
- GlaxoSmithKline
Leg Ulcers Venous, Dehiscence, Surgical Wound
Blu Light for Ulcers Reduction
Multi-center study on the effectiveness of treatment with a blue light medical device (EmoLED) in the reduction of ulcer surface in 10 weeks.
- Trial name
- BLUR (NCT04018924)
- Testing
- Illumination with blue light (400-430nm) for 60 seconds with a power density of 120mW/sqcm (EmoLED device)
- Where
- 7 sites in Italy
- Volunteers
- 90 people
- Sponsor
- Emoled
Chronic Subdural Hematoma
Surgical Management of Chronic Subdural Hematoma: Clinical Outcomes Following Single VS Double Burr Holes Evacuation
This study aims to evaluate and compare the clinical and radiological outcomes of patients with chronic subdural hematoma (CSDH) undergoing surgical evacuation using either single or double burr-hole craniostomy.
- Trial name
- NCT07688473
- Testing
- Chronic Subdural Hematoma Evacuation
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Sohag University
Double Outlet Right Ventricle, Transposition of the Great Arteries
Clinical Impact of Rapid Prototyping 3D Models for Surgical Management
Patient-specific, 3D printed models have been utilized in preoperative planning for many years. Among researchers and clinicians, there is a perception that preoperative exposure to 3D printed models, derived from patient images…
- Conditions
- Double Outlet Right Ventricle, Transposition of the Great Arteries, Truncus Arteriosus, Congenitally Corrected Transposition of the Great Arteries
- Trial name
- NCT04788082
- Testing
- 3D Printed Heart Model
- Where
- 3 sites in United States
- Sponsor
- Children's National Research Institute
Non-Cardiac/ Non-Thoracic Surgery, Abdominal Surgery
Assisted Fluid Management IDE Study
The primary objective of this study is to evaluate the performance of the Acumen™ Assisted Fluid Management (AFM) Feature in its ability to predict a subject's fluid responsiveness.
- Conditions
- Non-Cardiac/ Non-Thoracic Surgery, Abdominal Surgery, Pelvic Surgery, Major Peripheral Vascular Surgery
- Trial name
- AFM (NCT03469570)
- Testing
- EV1000 Clinical Platform with Assisted Fluid Management (AFM) Feature
- Where
- 10 sites in United States
- Volunteers
- 330 people
- Sponsor
- Edwards Lifesciences
Abdominal Aortic Aneurysm, Surgery
Aneurysm Diameter and Surgical Outcome
Aneurysm diameter is an important risk for rupture and related death in affected patients. This study will evaluate whether aneurysms size may even influence post procedural outcomes both in open surgical repair and in…
- Conditions
- Abdominal Aortic Aneurysm, Surgery, Outcome, Fatal
- Trial name
- ADASO (NCT04422054)
- Testing
- Open Surgery, Endovascular Surgery
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- University of Catanzaro
Vascular Diseases, Patient Empowerment
PREMs In Vascular SurgERy Enhancement Study
THE PROBLEM: Patient Reported Experience Measures (PREMs) ask patients about their healthcare service experience. It gives them a voice to share their views.
- Conditions
- Vascular Diseases, Patient Empowerment, Patient Satisfaction, Patient Engagement
- Trial name
- PREMIERE (NCT06363175)
- Where
- United Kingdom
- Volunteers
- 330 people
- Sponsor
- Cardiff and Vale University Health Board
Percutaneous Coronary Intervention, Myocardial Revascularization
Baduanjin Intervention in Clinical Studies After Coronary Revascularization Surgery
1. To evaluate the efficacy and safety of the Baduanjin exercise programme in patients following coronary revascularisation surgery; 2.
- Conditions
- Percutaneous Coronary Intervention, Myocardial Revascularization, Coronary Artery Disease
- Trial name
- NCT07607951
- Testing
- Standardized Western medical treatment + Standardized Baduanjin rehabilitation training, Standardized Western medical treatment + Aerobic exercise training
- Volunteers
- 310 people
- Sponsor
- Liu Qiang
Atherosclerosis, Ischemia Limb
Efficacy and Safety Comparison of the Endovascular and the Hybrid Methods for the Treatment of Prolonged Atherosclerotic Lesions of the Femoral-popliteal Segment Above the Knee, TASC II, Type D
A recent study, where the authors studied the effectiveness of stenting of prolonged lesions (>200 mm) of the femoral-popliteal segment with nitinol stents (TASC II, D), showed unsatisfactory primary patency rates (45%) within 2…
- Conditions
- Atherosclerosis, Ischemia Limb, Superficial Femoral Artery Occlusion, Popliteal Artery Occlusion
- Trial name
- NCT04590131
- Testing
- recanalization of the femoral-popliteal arterial segment above the knee with angioplasty and stenting with a biomimetic interwoven nitinol stent, supplemented by fasciotomy in Hunter's canal., recanalization of the femoral-popliteal arterial segment above the knee with angioplasty and stenting with a biomimetic interwoven nitinol stent.
- Where
- Russia
- Volunteers
- 100 people
- Sponsor
- Meshalkin Research Institute of Pathology of Circulation
Feasibility, Active Decision Support System
Evaluation of an Active Decision Support System for Hemodynamic Optimization During High Risk Vascular Surgery
Rivers et al. laid the foundation for modern hemodynamic and fluid management by establishing goal directed therapy (GDT) for the treatment of sepsis using fluid and inotropic and vasoactive agents.
- Conditions
- Feasibility, Active Decision Support System, Goal Directed Therapy
- Trial name
- NCT03012919
- Testing
- active decision support system
- Volunteers
- 31 people
- Sponsor
- Medical University of Vienna
Adjunct to Hemostasis During Vascular Surgery
Efficacy and Safety of TISSEEL Lyo Compared to Manual Compression as an Adjunct to Haemostasis
The primary objective of the study is to evaluate the efficacy of TISSEEL Lyo for haemostasis in patients receiving peripheral vascular prosthetic expanded polytetrafluoroethylene (ePTFE) conduits, as compared to a control arm…
- Trial name
- NCT04083807
- Testing
- TISSEEL Lyo, Manual compression with surgical gauze pads
- Where
- 5 sites in Russia
- Volunteers
- 104 people
- Sponsor
- Baxter Healthcare Corporation
Hemostasis
Safety and Efficacy of Topical Thrombin (Human) Grifols as an Adjunct to Hemostasis During Surgery
This purpose of this clinical trial was to study the safety and efficacy of Topical Thrombin (Human) Grifols as an add-on treatment to help stop bleeding during vascular, liver, soft tissue, and spinal surgical procedures.
- Trial name
- NCT02014402
- Testing
- Human thrombin, Bovine thrombin
- Where
- 20 sites in United States
- Volunteers
- 181 people
- Sponsor
- Instituto Grifols, S.A.
Intra Abdominal Pressure, Abdominal Compartment Syndrome
Intra-abdominal Hypertension and Abdominal Compartment Syndrome in Patients After Pancreatic Procedures.
This study investigates the development of intra-abdominal hypertension and compartment syndrome in patients undergoing elective pancreatic procedures.
- Conditions
- Intra Abdominal Pressure, Abdominal Compartment Syndrome, Pancreatic Surgery, Pancreatic Fistula After Pancreaticoduodenectomy
- Trial name
- HYPA (NCT06672601)
- Where
- Czechia
- Volunteers
- 150 people
- Sponsor
- Charles University, Czech Republic
Anesthesia
Reduction of Pulmonary Artery Pressure in Patients Subjected to Cardiac Surgery
The aim of this study is to assess the ability of clonidine to reduce the mean pulmonary artery pressure in patients with pulmonary hypertension subjected to cardiac surgery.
- Trial name
- NCT01597427
- Testing
- Clonidine
- Where
- Brazil
- Volunteers
- 29 people
- Sponsor
- Federal University of São Paulo
Central Retinal Vein Occlusion
Retinal Endo Vascular Surgery for Central Retinal Vein Occlusion
Patients with Central Retinal Vein Occlusion will undergo vitrectomy, a small needle of about 71 micron will enter a branch retinal vein and TPA will be injected into the obstracted vein.
- Trial name
- NCT00383773
- Testing
- Retinal endo vascular surgery
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Coronary Artery Disease
PCI vs. CABG in the Treatment of Unprotected Left Main Stenosis
Coronary Artery Bypass Grafting Versus Drug Eluting Stent Percutaneous Coronary Angioplasty in the Treatment of Unprotected Left Main Stenosis.
- Trial name
- LeftMain/NOBLE (NCT01496651)
- Testing
- Percutaneous coronary intervention, Coronary artery bypass graft operation
- Where
- Denmark
- Volunteers
- 1,201 people
- Sponsor
- Evald Hoej Christiansen
Varicose Veins
Hypnoanalgesia in Surgical and Endovenous Treatment of Varicosis
Endoveinous treatment of saphenous varicoses and phlebectomia of tributary veins are commonly performed under local anesthesia. Hypnoanalgesia might reduce perinterventional pain.
- Trial name
- NCT03601572
- Testing
- No intervention
- Volunteers
- healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Coronary Artery Bypass Graft Triple Vessel, Heart Valve Diseases
Preoperatively Orientation in Cardiac Surgery: Nurses Intervention on Patients Recovery
The purpose of this study is to determine whether the guidelines preoperative performed by a nurse contribute to the recovery of the patient submitted to cardiac surgery compared with the guidelines for routine.
- Trial name
- NCT01559610
- Testing
- Intervention Group
- Where
- Brazil
- Volunteers
- 180 people
- Sponsor
- Instituto de Cardiologia do Rio Grande do Sul
Blood Loss, Surgical
QStat in Liver Transplant
This study will assess the clinical performance of the Quantra System with the QStat Cartridge in the liver transplant population.
- Trial name
- NCT04114253
- Testing
- Quantra System
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- HemoSonics LLC
BPD - Bronchopulmonary Dysplasia, Pulmonary Hypertension
Safety and PK-PD Study of Oral L-CIT in Preterm Infants With BPD±PH and NEC
The purpose of this study is to evaluate the safety and explore the PK/PD of L-CIT supplementation in preterm infants to prevent the development of inflammatory pathways initiated by low levels of plasma CIT, specifically in…
- Conditions
- BPD - Bronchopulmonary Dysplasia, Pulmonary Hypertension, NEC
- Trial name
- NCT05636397
- Testing
- L-Citrulline
- Where
- Canada
- Volunteers
- 36 people
- Sponsor
- The Hospital for Sick Children