Clinical trials: Vascular Thrombosis
Retinal Vein Occlusion
Ultra-wide Fluorescein Angiography in Patients With Central Retinal Vein Occlusion Treated by Afilbercept
In patients with macular edema secondary to CRVO, Aflibercept demonstrated efficacy and safety in 2 parallel trials, interventional phase III studies, COPERNICUS study performed in United States and GALILEO study performed in…
- Trial name
- HERMES (NCT02880644)
- Where
- 9 sites in France
- Volunteers
- 65 people
- Sponsor
- Centre Hospitalier Intercommunal Creteil
Pulmonary Embolism
A Registry Study on Biomarkers of Pulmonary Embolism
The purpose of the study is to evaluate the value of biomarkers in the diagnosis and risk stratification of patients with suspected pulmonary embolism.
- Trial name
- BIO-PE (NCT04118634)
- Where
- China
- Volunteers
- 480 people, healthy volunteers welcome
- Sponsor
- Beijing Institute of Heart, Lung and Blood Vessel Diseases
Thromboembolism, Acute Lymphoblastic Leukemia
Thromboembolic Complications Related to Asparaginase in Children With Acute Lymphoblastic Leukemia (ALL) Treated According to NOPHO ALL 2008
The study will examine the prevalence of venous thromboembolism in children with acute lymphoblastic leukaemia treated in accordance with NOPHO ALL-2008.
- Trial name
- NCT00982514
- Where
- Norway
- Volunteers
- 60 people
- Sponsor
- Oslo University Hospital
Pulmonary Embolism
Diclofenac for Submassive PE
The primary objective is to demonstrate the clinical benefits of diclofenac (added to standard anticoagulant therapy) over placebo in normotensive patients with acute symptomatic pulmonary embolism and right ventricular…
- Trial name
- AINEP-1 (NCT01590342)
- Testing
- Diclofenac
- Where
- Spain
- Volunteers
- 34 people
- Sponsor
- Ministry of Health, Spain
Colorectal Surgery, VTE (Venous Thromboembolism)
A Multicenter, Open-Label, Non-Inferiority Randomized Controlled Trial of Postoperative VTE Prevention in Chinese Patients After Colorectal Cancer Surgery
research objective 1. Optimize VTE prevention management after CRC surgery. 2. Improve the prevention and treatment level of VTE in current perioperative patients. 3. Reduce the social burden of VTE related diseases.
- Trial name
- NCT06583330
- Testing
- Low Molecular Weight Heparin (dalteparin)
- Volunteers
- 1,448 people
- Sponsor
- Beijing Friendship Hospital
Thrombosis in Children
Evaluation of Risk Factors and Outcome of Thrombosis in Children
Pediatric thrombosis is multifactorial, and usually risk factors either congenital or acquired are present. Patient may has one risk factor or more such as sepsis, cancers, congenital heart disease, post surgery , central venous…
- Trial name
- NCT05840744
- Testing
- complete blood count
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Sohag University
Neovascular Age-related Macular Degeneration
Blood Coagulation Parameters in Patients Receiving Intravitreal Aflibercept for Age-related Macular Degeneration
This study aims to evaluate coagulation parameters in treatment naive patients with neovascular age-related macular degeneration (AMD).
- Trial name
- NCT03509623
- Testing
- Blood sampling through direct peripheral venous puncture
- Where
- Greece
- Volunteers
- 47 people
- Sponsor
- University Hospital of Patras
Contraception, Female Contraception
A Postmarketing Study of the Risk of Venous Thromboembolism (Blood Clots), Myocardial Infarction (Heart Attacks), and Stroke Among Women Using ORTHO EVRA (Norelgestromin and Ethinyl Estradiol Contraceptive Patch) Compared With Women Who Take Oral Contraceptives for Birth Control
The purpose of the study is to use data from a health care information database to assess the risk of venous thromboembolism (blood clots), myocardial infarction (heart attacks), and stroke among women using a transdermal…
- Trial name
- NCT00377988
- Testing
- Transdermal Contraceptive System, Norgestimate-containing oral contraceptives with EE
- Volunteers
- 423 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Thrombosis, Acute Coronary Syndrome
Histopathology of the Aspirated Thrombus During Acute Myocardial Infarction
This study was initiated on the preliminary premise that a thrombus whose formation was triggered by a thrombogenic substrate, such as within an atherosclerotic plaque (Tissue factor initiated thrombus), may evolve differently…
- Trial name
- NCT01705665
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Hillel Yaffe Medical Center
Blood Coagulation
Observational Study Assessing the Impact of Exposure to THROMBIN-JMI® on Coagulation Parameters.
The purpose of this study is to assess the effect of possible exposure to THROMBIN JMI® on activated partial thromboplastin time (aPTT) at 48 hours post surgery in subjects with likelihood of prior exposure to THROMBIN JMI®…
- Trial name
- MOSAIC (NCT00775398)
- Where
- 43 sites in United States
- Volunteers
- 553 people
- Sponsor
- Pfizer
Lung Cancer, Stomach Cancer
Effect of Precise Grip Strength Training on PICC Catheter-Related Thrombosis in Cancer Patients
In this study, color Doppler ultrasound diagnostic instrument and electronic grip device were used to determine the best grip strength of patients with tumor PICC catheterization, formulate precise and standardized grip strength…
- Conditions
- Lung Cancer, Stomach Cancer, Breast Cancer, Liver Cancer
- Trial name
- NCT05638048
- Testing
- Precision grip training, Use maximum strength grip training, Health education on routine grip strength training
- Where
- China
- Volunteers
- 270 people
- Sponsor
- Junyan Zhao
Cardiovascular Diseases, Venous Thromboembolism
Genetic Epidemiology of Venous Thromboembolism
To determine the genetic epidemiology, including genetic and environmental interactions of the multifactorial disease, venous thromboembolism (VTE).
- Trial name
- NCT00005543
- Volunteers
- 3,135 people
- Sponsor
- Mayo Clinic
Prosthetic Cardiac Valve Thrombosis, Cerebrovascular Accident
Rule Out Transcatheter Aortic Valve Thrombosis With Post Implantation Computed Tomography (RETORIC)
The RETORIC study is a prospective cohort study with a primary aim to assess the incidence and independent predictors of reduced leaflet motion and valve thrombosis after TAVI procedure using multimodality imaging strategy…
- Conditions
- Prosthetic Cardiac Valve Thrombosis, Cerebrovascular Accident, Prosthetic Valve Malfunction
- Trial name
- RETORIC (NCT02826200)
- Testing
- Acenocoumarol, Standard of care
- Where
- Hungary
- Volunteers
- 200 people
- Sponsor
- Semmelweis University Heart and Vascular Center
Cerebral Venous Thrombosis
Study of Rivaroxaban for CeREbral Venous Thrombosis
SECRET examines the safety of rivaroxaban versus standard-of-care for treatment of symptomatic cerebral venous thrombosis, initiated within 14 days of diagnosis.
- Trial name
- SECRET (NCT03178864)
- Testing
- Rivaroxaban, Standard of care
- Where
- 11 sites in Canada
- Volunteers
- 55 people
- Sponsor
- University of British Columbia
Transcatheter Aortic Valve Replacement, Antithrombotic Therapy
Antithrombotic Strategy Based on Clinical Events and 4D-CT for Patients After TAVR
This is a multicenter, open-label, randomized controlled study meant to test the superior efficacy of oral anticoagulation (OAC) therapy versus single antiplatelet therapy (SAPT) in patients after TAVR.
- Conditions
- Transcatheter Aortic Valve Replacement, Antithrombotic Therapy, Bioprosthetic Valve Thrombosis
- Trial name
- NCT05375474
- Testing
- Oral anticoagulation therapy, Single antiplatelet therapy
- Where
- China
- Volunteers
- 650 people
- Sponsor
- China National Center for Cardiovascular Diseases
Branch Retinal Vein Occlusion, Retinal Blood Flow
Assessment of Retinal Vessel Diameters and Red Blood Velocities in Patients With BRVO and Healthy Subjects
Assessment of retinal vessel calibers combined with bidirectional Fourier domain optical coherence tomography (FDOCT) for measurement of retinal blood velocities is a new and sophisticated method for assessing retinal blood flow…
- Conditions
- Branch Retinal Vein Occlusion, Retinal Blood Flow, Retinal Oxygen Saturation
- Trial name
- NCT01746615
- Testing
- Dynamic Vessel Analyzer, Bidirectional Fourier-Domain Optical Coherence Tomography (FDOCT)
- Where
- Austria
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Portal Vein Thrombosis
Role of EUS Guided FNA of Portal Vein Thrombus in the Diagnosis and Staging of Hepatocellular Carcinoma
Since not every portal vein thrombus (PVT) in a patient with hepatocellular carcinoma (HCC) is a tumor thrombus, since the nature of the thrombus will ultimately determine the course of treatment, and since PVT may be even the…
- Trial name
- NCT03902678
- Testing
- EUS guided fine needle aspiration of portal vein thrombus
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Mansoura University
Acute Leukemia, Newly Diagnosed Acute Leukemia
Real World Assessment of Venous Thromboembolic Risk in Hospitalized Patients With Acute Leukemia
This is a observational study designed to identify risk factors for venous thromboembolism in patients with newly diagnosed acute leukemia at the time of first admission to a Hematology Ward.
- Conditions
- Acute Leukemia, Newly Diagnosed Acute Leukemia, Thromboprophylaxis, Thromboprophylaxis in Acute Leukemia
- Trial name
- ReVeAL (NCT07831668)
- Volunteers
- 250 people
- Sponsor
- Gruppo Italiano Malattie EMatologiche dell'Adulto
Cardiovascular Diseases, Heart Diseases
Genetic Architecture of Plasma T-PA and PAI-1
To determine the effects of six genes on thrombotic risk factors known to be associated with the development of heart disease.
- Conditions
- Cardiovascular Diseases, Heart Diseases, Thrombosis, Atherosclerosis
- Trial name
- NCT00007410
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Polycythemia Vera
The Benefit/Risk Profile of AOP2014 in Low-risk Patients With PV
The Low-PV study is a multicenter, phase II, randomized trial aimed to assess whether the addition of Pegylated Proline-interferon-alpha-2b to the best therapeutic current strategy available based on phlebotomies and low dose…
- Trial name
- Low-PV (NCT03003325)
- Testing
- AOP2014, Phlebotomies, ASA
- Where
- 23 sites in Italy
- Volunteers
- 127 people
- Sponsor
- FROM- Fondazione per la Ricerca Ospedale di Bergamo- ETS
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.