Clinical trials: Vascular Thrombosis
Acute Thrombosis of Deep Veins of Proximal Lower Extremity
DUTCH CAVA-trial: CAtheter Versus Anticoagulation Alone for Acute Primary (Ilio)Femoral DVT.
Rationale: Iliofemoral deep venous thrombosis (IFDVT) is associated with significant post thrombotic morbidity. The presence of both obstruction and reflux significantly increases the chances for development of post-thrombotic…
- Trial name
- NL28394 (NCT00970619)
- Testing
- Ekos endowave system thrombolysis
- Where
- 16 sites in Netherlands
- Volunteers
- 184 people
- Sponsor
- Maastricht University Medical Center
Infertility, Hyperstimulation Syndrome, Ovaian
Vascular Cell Activation, Cell-Derived Microparticles and In Vitro Fertilisation, and In Vitro Fertilisation
Introduction: Ovarian hyperstimulation syndrome (OHSS) is an iatrogenic phenomenon, poorly understood and difficult to predict, complicating intense ovarian stimulation cycle.
- Conditions
- Infertility, Hyperstimulation Syndrome, Ovaian, Thrombosis
- Trial name
- PREDHSO (NCT03051230)
- Volunteers
- 50 people
- Sponsor
- Poissy-Saint Germain Hospital
Coronary Bifurcation Lesions, Death
Mini-Crush Or Controlled Balloon-Crush For True Coronary Bifurcation Lesions
The mini-crush technique is one of the leading 2-stent techniques frequently applied by interventional cardiologists to treat complex bifurcation lesions.
- Conditions
- Coronary Bifurcation Lesions, Death, Myocardial Infarction (MI), Stent Thrombosis
- Trial name
- NCT06880978
- Where
- Turkey (Türkiye)
- Volunteers
- 400 people
- Sponsor
- Istanbul Mehmet Akif Ersoy Educational and Training Hospital
Cerebral Venous Thrombosis
Clinical Deterioration in Cerebral Venous Thrombosis: A Predictive Study
The objective of this retrospective, prospective, multicenter cohort study is to determine the risk factors for deterioration of CVT patients after admission and establish a scoring model for risk stratification of patients.
- Trial name
- NCT06266585
- Where
- China
- Volunteers
- 273 people
- Sponsor
- Beijing Tiantan Hospital
CT - Coronary Thrombosis
The Diagnostic Power Of Coronary CT Angiography In Patients With Chest Pain And Zero Calcium Score
To prove the non-used wide diagnostic range of CCTA in diagnosis of other causes of chest pain in addition to the traditional known role in coronary atherosclerosis.
- Trial name
- NCT06552663
- Testing
- CCTA
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Assiut University
Thrombocytopenia, Thrombosis
Evaluation of Argatroban Injection in Pediatric Patients Requiring Anticoagulant Alternatives to Heparin
The purpose of this study is to evaluate the safe and effective dose of Argatroban for prophylaxis and/or treatment of thrombosis in pediatric patients with current or previous diagnosis of heparin-induced thrombocytopenia (HIT)…
- Trial name
- NCT00039858
- Testing
- Argatroban
- Where
- 13 sites in United States
- Volunteers
- 24 people
- Sponsor
- Encysive Pharmaceuticals
Neovascular Age-related Macular Edema, Diabetic Macular Edema
Anti-VEGF in Real-world
Anti-vascular endothelial growth factor therapy is the major intervention for treating ischemic retina diseases. According to FDA and China Food and Drug Administration, Ranibizumab, Aflibercept, and Conbercept are major types of…
- Conditions
- Neovascular Age-related Macular Edema, Diabetic Macular Edema, Choroidal Neovascular Membrane, Non-proliferative Diabetic Retinopathy
- Trial name
- NCT05222633
- Testing
- Ranibizumab, Aflibercept, Conbercept
- Where
- China
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Wenbin Wei
Covid19
Prevalence of Thrombosis in COVID-Patients
Examination of the prevalence of thrombosis in COVID-patients, especially in an out-patient setting. Assessment by duplex sonography. If thrombosis is detected, we will correlate it with immunity status.
- Trial name
- NCT04615026
- Testing
- duplex sonography
- Where
- Germany
- Volunteers
- 525 people
- Sponsor
- University Hospital Augsburg
Hepatocellular Carcinoma, Portal Vein Thrombosis
Prognostic Value Related to the Presence of Thrombosis or Portal Vein Invasion in Patients With Hepatocellular Carcinoma Submitted to Surgery
A retrospective study based on analysis of medical records of patients with hepatocellular carcinoma treated at the Hospital Sírio-Libanês (Sao Paulo-Brazil) between 2001 and 2011 with diagnosis confirmed by imaging or…
- Conditions
- Hepatocellular Carcinoma, Portal Vein Thrombosis, Hepatic Portal Vein Tumor Invasion
- Trial name
- HSL2012-06 (NCT01690715)
- Where
- Brazil
- Volunteers
- 50 people
- Sponsor
- Hospital Sirio-Libanes
Hepatocellular Carcinoma, Portal Vein Thrombosis
Proton Beam Radiotherapy Followed by Tecentriq and Avastin for Primary Liver Cancer With Vp2-4 Portal Vein Invasion
This study is investigator initiated, single-institution, prospective, phase 2 open-label study to determine the efficacy and safety of combination therapy of atezolizumab/bevacizumab and proton beam therapy to portal vein tumor…
- Trial name
- NCT05625893
- Testing
- PBT and atezolizumab/bevacizumab
- Where
- South Korea
- Volunteers
- 63 people
- Sponsor
- Samsung Medical Center
Thromboembolism
Factor Xa Inhibitor YM150 for the Prevention of Blood Clot Formation in Veins After Scheduled Hip Replacement (ONYX-2)
The purpose of this study is to find the best possible (optimal) dose (effect versus adverse events) of YM150 to prevent the risk of blood clot formation after scheduled hip replacement surgery.
- Trial name
- NCT00353678
- Testing
- YM150
- Where
- 79 sites in Austria, Bosnia and Herzegovina and 15 more
- Volunteers
- 1,141 people
- Sponsor
- Astellas Pharma Inc
Artery; Thrombosis
The TENDERA Multicenter Clinical Trial
TENDERA is a multicenter randomized controlled trial to compare traditional entry point in the radial artery for TRI and distal puncture at the anatomical snuffbox area for transradial Interventions.
- Trial name
- TDR (NCT04211584)
- Testing
- transradial interventions
- Where
- Russia
- Volunteers
- 850 people
- Sponsor
- Center of Endosurgery and Lithotripsy, Moscow, Russia
Embolism, Air
Gas Embolism With Use of Argon Plasma Coagulation
The purpose of this study is to use transesophageal echocardiography (TEE) to determine the incidence, severity, and clinical significance of gas bubbles during argon plasma coagulation (APC).
- Trial name
- NCT00676858
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Beth Israel Deaconess Medical Center
Retinal Vein Occlusion, Macular Edema
Ultra-wide-field Fluorescein Angiography in Patients With Macular Edema Secondary to Retinal Vein Occlusion
This study mainly observed the ischemic index and vascular leakage index changes on ultra-wide field fluorescence angiography after anti-VEGF treatment , and whether these changes correlated with treatment efficacy in patients…
- Trial name
- UWFA-RVO-ME (NCT04140448)
- Testing
- Ranibizumab 0.5 MG/0.05 ML Intraocular Solution [LUCENTIS], Ultra-wide Fluorescein Angiography
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Renmin Hospital of Wuhan University
Raynaud's Disease
Nova Cold Hands Raynaud's Disorder, a Disease Which Results in Decreased Blood Flow to the Hands and Feet.
Patients presenting to UIC rheumatology clinic with Raynaud's disorder and scleroderma will be asked to participate. 10 hands of patients with both Raynaud's disorder and scleroderma will be studied.
- Trial name
- NCT02615964
- Testing
- Nova Flow Procedure
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Acute Ischemic Stroke, Large Vessel Occlusion
Acute Ischemic Stroke EndoVascular Therapy: a Multicenter REGISTRY Study
A Multicenter Registry of Endovascular Treatment for Acute Ischemic Stroke.
- Conditions
- Acute Ischemic Stroke, Large Vessel Occlusion, Thrombectomy, Thrombosis
- Trial name
- NCT05864638
- Testing
- Endovascular treatment
- Where
- China
- Volunteers
- 10,000 people
- Sponsor
- Changhai Hospital
COVID, Sars-CoV2
Preventing COVID-19 Complications With Low- and High-dose Anticoagulation
The ongoing COVID-19 pandemic affects millions of humans worldwide and has led to thousands of acute medical hospitalizations. There is evidence that hospitalized cases often suffer from an important infection-related…
- Trial name
- COVID-HEP (NCT04345848)
- Testing
- Enoxaparin
- Where
- 4 sites in Switzerland
- Volunteers
- 160 people
- Sponsor
- University Hospital, Geneva
Brain Injury, Venous Thrombosis
The Use of Low Molecular Weight Heparin in Traumatic Brain Injury
To study the safety and efficacy of early administration of Low Molecular Weight Heparin to patients with traumatic brain injury.
- Trial name
- NCT00170378
- Testing
- Enoxaparin
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Hennepin Healthcare Research Institute
Deep Vein Thrombosis, Total Hip Prosthesis
Generation of Thrombin and Prediction of Deep Vein Thrombosis Post Prosthetic Orthopedic Surgery of the Lower Limbs
The numerical ratio between the value of the thrombin generation test performed without soluble thrombomodulin and the value of the thrombin generation test performed in the presence of soluble thrombomodulin, performed…
- Conditions
- Deep Vein Thrombosis, Total Hip Prosthesis, Knee Prosthesis
- Trial name
- GT-PT (NCT03634124)
- Testing
- Blood test, Doppler ultrasound
- Where
- France
- Volunteers
- 146 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Venous Thromboembolism, Deep Vein Thrombosis
Fixed Dose Heparin Study
FIDO was a multicentred randomized, open-label trial that compared fixed-dose UFH with fixed-dose LMWH for initial treatment of VTE. Patients were followed for 3 months during which they received warfarin (target INR 2.0-3.0).
- Conditions
- Venous Thromboembolism, Deep Vein Thrombosis, Pulmonary Embolism
- Trial name
- NCT00182403
- Testing
- UFH 250 U/kg or LMWH 100 U/kg sc twice daily
- Where
- 8 sites in Canada, New Zealand
- Volunteers
- 866 people
- Sponsor
- McMaster University
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