Clinical trials: Vascular Thrombosis
Kidney Failure
Clotting With Different Dialyzer Membranes
Primary Objective: The purpose of this study is to measure the amount of convection achieved with two different haemodiafilters designed for haemodiafiltration and clotting during haemodiafiltration treatment.
- Trial name
- TAGPSOLACEA (NCT02546037)
- Testing
- FX100 dialyzer, SOLACEA 21H
- Volunteers
- 10 people
- Sponsor
- University College, London
Infant, Premature, Anticoagulants
Heparin Versus no Heparin on Duration of Peripherally Inserted Central Catheter (PICC) Patency in Neonates
Background: Heparin is an anticoagulant commonly used in the neonatal population as a means to prevent catheter related occlusion and malfunction by thrombosis (clot).
- Conditions
- Infant, Premature, Anticoagulants, Thrombosis
- Trial name
- NCT00879957
- Testing
- heparin, No heparin
- Where
- United States
- Sponsor
- The University of Texas Health Science Center at San Antonio
Thromboembolism
HTRS TE Registry (ThromboEmbolism Registry)
The TE Registry is a multi-institutional bioinformatics database for the collection of data relevant to TE. Participating HTRS affiliated study centers may enroll patients and enter data in the TE Registry by completing…
- Trial name
- NCT00266994
- Where
- United States
- Volunteers
- 2,760 people
- Sponsor
- Nationwide Children's Hospital
Venous Thrombosis
Study of a Novel Thrombectomy Device to Treat Acute Iliofemoral Deep Venous Thrombosis
The purpose of this study is to determine whether the novel aspiration thrombectomy device combined with catheter-directed thrombolysis is effective in the treatment of acute iliofemoral deep venous thrombosis (IF-DVT).
- Trial name
- NCT02414802
- Testing
- a manual spiral thrombus broken suction device, catheter-directed thrombolysis, low-molecular-weight heparin calcium
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Xuzhou Medical University
Stroke, Stroke, Acute
Impact of COVID-19 Vaccines on Cerebrovascular Health
Safe and effective severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccines may reduce the transmission of and achieve population immunity against the COVID-19 pandemic, which accounted for more than 3.75million…
- Conditions
- Stroke, Stroke, Acute, Stroke, Ischemic, Dementia
- Trial name
- NCT04992195
- Testing
- Laboratory tests and Montreal Cognitive Assessment
- Where
- Hong Kong
- Volunteers
- 415 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Covid19, Pulmonary Fibrosis
COVID-19 Pathophysiology of Long Term Implications
Coronavirus disease 2019 (COVID 19) is primarily a respiratory viral infection. At the time of writing this protocol, more than 25 million people have been affected globally.
- Conditions
- Covid19, Pulmonary Fibrosis, Organising Pneumonia, Thromboembolism
- Trial name
- NCT04813575
- Testing
- Cryo lung biopsies
- Where
- Saudi Arabia
- Volunteers
- 60 people
- Sponsor
- King Faisal Specialist Hospital & Research Center
Non-valvular Atrial Fibrillation (NVAF)
Xarelto on Prevention of Stroke and Non-Central Nervous Systemic Embolism in Renally Impaired Korean Patients With Non-valvular Atrial Fibrillation
The purpose of the study is to evaluate the safety and effectiveness of Xarelto in renally impaired patients with NVAF under routine practice conditions.
- Trial name
- XARENAL (NCT03746301)
- Testing
- Rivaroxaban(Xarelto,BAY 59-7939)
- Where
- South Korea
- Volunteers
- 924 people
- Sponsor
- Bayer
Atrial Fibrillation
A Study Evaluating Safety and Tolerability of YM150 Compared to Warfarin in Subjects With Atrial Fibrillation
The purpose of this study is to investigate the optimal daily dose and dose regimen of YM150 in subjects with non-valvular atrial fibrillation (NVAF), primarily based on safety and tolerability data.
- Trial name
- OPAL-2 (NCT00938730)
- Testing
- YM150, Warfarin
- Where
- 170 sites in Australia, Austria and 21 more
- Volunteers
- 1,280 people
- Sponsor
- Astellas Pharma Inc
Venous Thromboembolism, Embolism and Thrombosis
Factor IX Inhibition in Thrombosis Prevention (The FIXIT Trial)
The purpose of this study is to determine whether TTP889 prevents venous thromboembolism following surgery to repair hip fracture.
- Conditions
- Venous Thromboembolism, Embolism and Thrombosis, Hip Fractures
- Trial name
- NCT00119457
- Testing
- TTP889
- Where
- 21 sites in Czechia, Denmark and 2 more
- Volunteers
- 300 people
- Sponsor
- vTv Therapeutics
Raynaud's Disease, Peripheral Vascular Disease
PF-00489791 For The Treatment Of Raynaud's
The investigators propose that once daily administration of PF-00489791, a phosphodiesterase inhibitor, will reduce vasospasm and improve symptoms and signs associated with Primary and Secondary Raynaud's Phenomenon.
- Trial name
- NCT01090492
- Testing
- PF-00489791
- Where
- 55 sites in United States, Canada and 9 more
- Volunteers
- 243 people
- Sponsor
- Pfizer
Pulmonary Embolism
Treating Pulmonary Embolism With Laguna Thrombectomy System (TRUST)
This is a prospective, multi-center, pivotal study to demonstrate the safety and effectiveness of the Laguna Thrombectomy System for the treatment of pulmonary embolism.
- Trial name
- TRUST (NCT06041594)
- Testing
- Laguna Thrombectomy System
- Where
- 21 sites in United States, Turkey (Türkiye)
- Volunteers
- 107 people
- Sponsor
- Innova Vascular, Inc.
Retinal Vein Occlusion, Macular Edema
Bevacizumab Versus Ranibizumab in Treatment of Macular Edema From Vein Occlusion
Antagonists of the vascular endothelial growth factor (VEGF) pathway are effective in treating macular edema resulting from retinal vein occlusion (RVO).
- Trial name
- CRAVE (NCT01428388)
- Testing
- Intravitreal injection of bevacizumab, Intravitreal injection of ranibizumab (0.5 mg per dose)
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Barnes Retina Institute
Thrombosis, Blood Coagulation Disorder
Dynamics of Platelet Activation in Patients With Ventricular Assist Device (VAD)
Consenting patients with end-stage heart failure that are implanted with/candidates for implant of a short-term/durable mechanical circulatory support device (e.g.: percutaneous microaxial pumps (Impella), extracorporeal membrane…
- Conditions
- Thrombosis, Blood Coagulation Disorder, Platelet Thrombus, Platelet Dysfunction Due to Aspirin
- Trial name
- PASVAD (NCT03255928)
- Testing
- PAS assay, TGT
- Where
- Italy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Scientific Institute San Raffaele
Myocardial Infarction, Acute, Left Ventricular Thrombus
Direct Oral Anticoagulants for Prevention of lEft ventRIcular Thrombus After Anterior Acute Myocardial InFarction - APERITIF
APERITIF is a prospective randomized open-label, blinded end-point (PROBE) trial, nested in the ongoing the "FRENCHIE" registry, a French multicenter prospective observational study granted by "ANR-RHU Grand Emprunt", in which…
- Trial name
- APERITIF (NCT05077683)
- Testing
- Rivaroxaban 2.5 MG [Xarelto], DAPT strategy
- Where
- France
- Volunteers
- 560 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Deep Venous Thrombosis
Pneumatic Compression for Preventing Venous Thromboembolism
Patients admitted to the intensive care unit are at high risk of developing clots in the veins of the lower extremities. The objective of this study is to examine whether the use of a device that provides intermittent compression…
- Trial name
- PREVENT (NCT02040103)
- Testing
- pneumatic compression
- Where
- Saudi Arabia
- Volunteers
- 2,000 people
- Sponsor
- King Abdullah International Medical Research Center
Thromboembolic Disease
The Correlation of Lewis Antigens With VTE
The goal of this observational study is to learn if certain factors in a person's blood are linked to a history of venous thromboembolic disease (VTED), which includes conditions like deep vein thrombosis.
- Trial name
- NCT07402005
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Larissa University Hospital
Pulmonary Embolism
Low Dose Catheter Directed Thrombolysis for Acute Pulmonary Embolism
BETULA trial will compare the efficacy of low dose catheter directed thrombolysis (CDT) to unfractioned heparin (UFH) in patients with intermediary-high risk pulmonary embolism (PE).
- Trial name
- BETULA (NCT03854266)
- Testing
- Low dose alteplase, Unfractionated heparin, Infusion catheter
- Where
- Denmark
- Volunteers
- 60 people
- Sponsor
- University of Aarhus
Arteriovenous Fistula Thrombosis, Arteriovenous Fistula Stenosis
Isometric Preoperative Exercise on Autologous Arteriovenous Fistulas. Randomized Clinical Trial
A good vascular access (VA) is vital for hemodialysis (HD) patients. The start of HD with autologous arteriovenous fistula (AVF) means higher survival, lower sanitary costs and complications.
- Trial name
- PHYSICALFAV (NCT03213756)
- Testing
- Isometric exercises using Hand grip and elastic bands
- Where
- Spain
- Volunteers
- 138 people
- Sponsor
- Hospital General Universitario Gregorio Marañon
Myocardial Infarction, Percutaneous Coronary Intervention
Comparison of Titanium-Nitride-Oxide Coated Bio-Active-Stent (Optimax™) to the Drug (Everolimus) -Eluting Stent (Synergy™) in Acute Coronary Syndrome
The purpose of the prospective, randomized and a multicenter trial is to compare clinical outcome in patients presenting with ACS, treated with PCI using Optimax-BAS versus Synergy-EES.
- Conditions
- Myocardial Infarction, Percutaneous Coronary Intervention, Atherosclerosis
- Trial name
- TIDES-ACS (NCT02049229)
- Testing
- percutaneous coronary intervention
- Where
- 6 sites in Finland
- Volunteers
- 1,800 people
- Sponsor
- The Hospital District of Satakunta
Antiphospholipid Syndrome, Thrombosis
Apixaban for Secondary Prevention of Thromboembolism Among Patients With AntiphosPholipid Syndrome
This study is designed to compare the safety and effectiveness of two blood thinners, apixaban and warfarin, for the prevention of blood clots in patients who have a higher risk of blood clots than the general population, a…
- Trial name
- ASTRO-APS (NCT02295475)
- Testing
- Apixaban, Warfarin
- Where
- 2 sites in United States
- Volunteers
- 48 people
- Sponsor
- Scott C. Woller, MD
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.