Clinical trials: Vasospasm
Primary Raynaud's Phenomenon (PR), Genetic Mutations Causing PR
Prospective Multicenter Study on the Identification of Genetic Abnormalities Predisposing to Vasospasm From a Privileged Model: the Primary Raynaud's Phenomenon
Vasospasm is a transient contraction causing a decrease in caliber of a vessel and thus a decrease in vascularization in a vascular territory leading to suffering of tissue in the sector concerned.
- Conditions
- Primary Raynaud's Phenomenon (PR), Genetic Mutations Causing PR, Study of Patients and Their Relatives (With or Without Primary PR)
- Trial name
- RAY-GENE (NCT02202291)
- Testing
- Demonstration of genetic mutations causing Raynaud's phenomenon
- Where
- 6 sites in France
- Volunteers
- 258 people, healthy volunteers welcome
- Sponsor
- Nantes University Hospital
Radial Artery Spasm, Radial Artery Access
The Effect of Using Virtual Reality Glasses on Anxiety-related Radial Vasospasm in Patients Undergoing Transradial Coronary Angiography
Compared to transfemoral access, transradial access is a safe and effective method for coronary interventions, associated with lower rates of vascular complications, including major bleeding.
- Conditions
- Radial Artery Spasm, Radial Artery Access, Virtual Reality
- Trial name
- NCT06726031
- Testing
- wearing VR glass
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Mersin University
SAH (Subarachnoid Hemorrhage), Cerebral Vasospasm
Acupuncture for Cerebral Vasospasm After Subarachnoid Hemorrhage
This study will evaluate acupuncture's effect of preventing vasospasm after SAH. A total of 80 participants will be recruited and will be randomized to a study group or a control group.
- Trial name
- NCT02275949
- Testing
- acupuncture, Electroacupuncture, Intradermal acupuncture
- Where
- South Korea
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Kyung Hee University Hospital at Gangdong
Aneurysm
Delayed Vasospasm After Aneurysm With the Standardization Treatment of Traditional Chinese Medicine
Delayed vasospasm (DCVS) is the most serious complication of aneurysmal subarachnoid hemorrhage (aSAH) perioperative period ,the incidence rate up to 30% to 90%, and often can cause severe brain ischemia or brain damage of…
- Trial name
- NCT01840761
- Testing
- herbal drug
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Guangzhou University of Traditional Chinese Medicine
Aneurysmal Subarachnoid Hemorrhage, Cerebral Vasospasm
Nitric Oxide Consumption as a Predictor of Vasospasm in Subarachnoid Hemorrhage
The goal of this observational study is to understand if angiographic cerebral vasospasm (CV) can be predicted by levels of nitric oxide (NO) consumption in patients with aneurysmal subarachnoid hemorrhage (SAH).
- Trial name
- NCT07614906
- Where
- 2 sites in United States, Italy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Vasospastic Syndrome
Registration of Skin-Temperatures and Sleep-Wake Behaviour
We study the skin-temperature (skin temperature measurement on different skin regions) and circadian rest-activity cycles (wrist activity monitoring) of 40 women in their daily life.
- Trial name
- NCT00319371
- Where
- Switzerland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Alzheimer's Disease, Glaucoma
Cellular Proteome From Leukocytes of Glaucoma Patients in Comparison With Patients With Alzheimer's Disease
Glaucoma is a worldwide leading cause of blindness. The key feature of this ocular neuropathy is characterized by an excavating optic nerve head.
- Trial name
- NCT00691340
- Volunteers
- healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Ischemia and No Obstructive Coronary Artery Disease, Coronary Microvascular Dysfunction
The DISCOVER INOCA Prospective Multi-center Registry
The overall objective of this multi-center registry is to identify specific phenotypes of INOCA with both an anatomic evaluation (coronary angiography and intravascular imaging) and physiologic assessment with the Abbott…
- Conditions
- Ischemia and No Obstructive Coronary Artery Disease, Coronary Microvascular Dysfunction, Coronary Vasospasm, Endothelial Dysfunction
- Trial name
- DISCOVER INOCA (NCT05288361)
- Testing
- Coroventis Coroflow Cardiovascular System and PressureWire™ X Guidewire
- Where
- 9 sites in United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Yale University
Subarachnoid Hemorrhage, Aneurysmal, Cerebral Vasospasm
Magnesium Treating Subarachnoid Hemorrhage Vasospasm
A randomized clinical trial investigating magnesium sulphate ability to reduce risk of cerebral vasospasm after acute subarachnoid hemorrhage hence improving outcome particularly in haptoglobin 2-2 patients who are highly…
- Trial name
- MATSH-SHapE (NCT04613960)
- Testing
- Magnesium sulfate, normal saline
- Where
- Egypt
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- General Committee of Teaching Hospitals and Institutes, Egypt
Tbi, Vasospasm
Cerebral Autoregulation and Vasospasm in Patients With TBI
Traumatic brain injury (TBI) affects 1.5 million patients per year in the United States, resulting in more than 50,000 deaths and more than 230,000 hospitalizations annually.
- Conditions
- Tbi, Vasospasm, Cerebral Ischemia, Cerebral Infarct
- Trial name
- NCT02351518
- Testing
- No intervention
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Microvascular Angina, Microvascular Coronary Artery Disease
EUROpean Coronary microCirculatory Resistance and Absolute Flow Trial
Rationale: coronary microvascular disease is a relatively 'new' entity within the field of cardiology. The investigators are able to investigate the microcirculation by measurements performed in the catheterization laboratory.
- Conditions
- Microvascular Angina, Microvascular Coronary Artery Disease, Coronary Vasospasm, Microvascular Resistance
- Trial name
- EURO-ccraft (NCT04598308)
- Testing
- absolute flow and resistance measurements
- Where
- Netherlands
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Catharina Ziekenhuis Eindhoven
Vasospastic Syndrome
Effect of Systemic Cooling in Vasospasms
This study tests whether women with Vasospastic Syndrome (VS) react more intensive than controls with distal vasomotions and choroidal blood flow changes to internal cooling/warming and external cooling/warming.
- Trial name
- NCT00409123
- Where
- Switzerland
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Subarachnoid Hemorrhage, Aneurysmal, Cerebrocardiac Syndrome
Mechanisms of Brain-Heart Injury of Post-Intracranial Hemorrhage
Intracranial hemorrhage is a condition characterized by high mortality rates and suboptimal functional outcomes. It precipitates both direct brain injury and subsequent secondary injuries, including delayed cerebral ischemia…
- Conditions
- Subarachnoid Hemorrhage, Aneurysmal, Cerebrocardiac Syndrome, Mass Spectrometry, Heart Failure
- Trial name
- NCT06906432
- Testing
- Multi-disciplinary assessment
- Where
- China
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Beijing Tiantan Hospital
Coronary Vasospasm
Effect of Glucose on Ocular Blood Flow
The primary objective is to assess the effect of glucose on retinal vascular diameter in otherwise healthy vasospastic subjects compared to non-vasospastic controls.
- Trial name
- NCT00350129
- Where
- Switzerland
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Radial Artery Spasm, Anxiety
The Effect of Music on Anxiety and Vasospasm in Patients Undergoing Transradial Angiography
Cardiovascular diseases are among the most significant health issues threatening human well-being, representing the leading cause of mortality and morbidity worldwide and in our country among non-communicable diseases.
- Conditions
- Radial Artery Spasm, Anxiety, Music Therapy
- Trial name
- NCT06800118
- Testing
- Music intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Mersin University
Subarachnoid Hemorrhage
Constitution of Cerebrospinal Fluid and Blood Database/Specimen in Acute Stage of Subarachnoid Hemorrhage (aSAH) Patients
Neuropeptide Y (NPY) may play a major role in the pathophysiology of aneurysmal subarachnoid hemorrhage (aSAH). To investigate the correlation of NPY in cerebrospinal fluid (CSF) and blood (serum) and the neurological outcome in…
- Trial name
- NCT01292278
- Where
- Germany
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Regensburg
Subarachnoid Hemorrhage, Aneurysmal, Delayed Cerebral Ischemia
Epigenome-wide DNA Methylation Profiling in Aneurysmal Subarachnoid Hemorrhage and Delayed Ischemic Neurologic Deficit
The goal of this observational study is to investigate DNA methylation changes in adults with bleeding from brain aneurysm, which is called aneurysmal subarachnoid hemorrhage (aSAH), and their association with delayed ischemic…
- Conditions
- Subarachnoid Hemorrhage, Aneurysmal, Delayed Cerebral Ischemia, Cerebral Vasospasm After Subarachnoid Hemorrhage, Intracranial Aneurysm
- Trial name
- NCT06881329
- Where
- Poland
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Pomeranian Medical University Szczecin
Virtual Reality, Atherosclerosis
Coronary Angiography THerapeutic Virtual Reality
The CATH-VR study will investigate the effect of virtual reality (VR) on patient pain, anxiety, and radial artery vasospasm during coronary angiography.
- Conditions
- Virtual Reality, Atherosclerosis, Coronary Artery Disease, Anxiety
- Trial name
- CATH-VR (NCT03490903)
- Testing
- Virtual Reality, Fentanyl Injection, Midazolam injection
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Parkinson's Disease, Glaucoma
Cellular Proteome From Leukocytes of Glaucoma Patients in Comparison With Patients With Parkinson's Disease
Glaucoma is a worldwide leading cause of blindness. The key feature of this ocular neuropathy is characterized by an excavating optic nerve head.
- Trial name
- NCT00327301
- Volunteers
- healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Medical Device Complication, Brain Injuries
Transcranial Doppler Using Wearable Ultrasound Patch
The main objective of this research is to measure the Doppler signal by the ultrasonic patch. Blood flow measurement is critical for vasospasm, stroke, and embolism monitoring on patients in the ICU or understanding the…
- Conditions
- Medical Device Complication, Brain Injuries, Brain Diseases, Stroke
- Trial name
- TCD (NCT06073145)
- Testing
- conventional transcranial Doppler probe and wearable ultrasound patch.
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego