Clinical trials: Vault
Pelvic Organ Prolapse
Restorelle® Mesh Versus Native Tissue Repair for Prolapse
The purpose of this study is to collect information on the safety and effectiveness of Restorelle Direct Fix mesh and the surgical procedure to implant Restorelle.
- Trial name
- NCT02162615
- Testing
- Restorelle Direct Fix A, Restorelle Direct Fix P, Native Tissue Repair Anterior
- Where
- 49 sites in United States, Australia and 4 more
- Volunteers
- 810 people
- Sponsor
- Coloplast A/S
Vaginal Vault Prolapse
Laparoscopic Versus Vaginal Approach Closure Complications
Hysterectomy is considered as a common operation in Gynecology. Hysterectomy could be made by vaginally, laparoscopically or abdominally.
- Trial name
- NCT05960292
- Testing
- Laparoscopic and Vaginal Hysterectomy
- Where
- Egypt
- Volunteers
- 56 people
- Sponsor
- Egymedicalpedia
Vaginal Vault Prolapse
Laparoscopic Sacrocolpopexy: Long Term Follow-up
The purpose of this study is to determine the long term results of laparoscopic sacrocolpopexy regarding anatomical results, recurrences, complications, further surgeries required, patients satisfaction and quality of life.
- Trial name
- NCT01394237
- Testing
- Examination
- Where
- Switzerland
- Volunteers
- 75 people
- Sponsor
- Kantonsspital Aarau
Uterine Prolapse, Vault Prolapse, Vaginal
Pectopexy Autologous Vs Mesh
prospective comparative study describing using autologous graft for uterine- vault - cervical suspension vs mesh in treatment of apical prolapse
- Trial name
- NCT06524700
- Testing
- pectopexy mesh, pectopexy autologous
- Where
- 2 sites in Egypt, Saudi Arabia
- Volunteers
- 20 people
- Sponsor
- Ain Shams Maternity Hospital
Cervix Cancer, Endometrial Cancer
2D vs 3D Planning for High-Dose Rate (HDR) Gynecological Brachytherapy
Demonstrate the limitations of conventional dosimetry (2D) for the adjuvant brachytherapy treatment and assess whether tridimensional dosimetry relates more faithfully with the occurrence of adverse effects.
- Trial name
- NCT02091050
- Testing
- 2D HDR planning, 3D HDR planning
- Where
- Brazil
- Volunteers
- 60 people
- Sponsor
- AC Camargo Cancer Center
Surgical Repair of Middle Compartment Prolapse (Vaginal Vault or Uterine Prolapse) With or Without Cystocele
Safety and Efficacy of a Transvaginal Suture Capturing Mesh Device
To perform a clinical safety and efficacy assessment of the Uphold LITE system for pelvic organ prolapse in a prospective multicenter, single cohort study.
- Trial name
- NCT01823055
- Testing
- Transvaginal suture capturing mesh device
- Volunteers
- 214 people
- Sponsor
- Karolinska Institutet
Uterovaginal and Vaginal Vault Prolapse
A New Technique for Sacrospinous-Sacrotuberous Fixation for the Treatment of Uterovaginal and Vaginal Vault Prolapse
This prospective interventional randomized controlled trial is conducted to compare a new technique for Sacrospinous-Sacrotuberous fixation with the traditional sacrospinous ligament fixation technique for treatment of…
- Trial name
- NCT03487328
- Testing
- Sacrospinous-Sacrotuberous fixation
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Ain Shams University
Vaginal Vault Prolapse, Sexual Function
Prophylactic Modified McCall Culdoplasty During Total Laparoscopic Hysterectomy
The purpose of this study is to assess the feasibility of performing prophylactic McCall culdoplasty at the time of total laparoscopic hysterectomy.
- Trial name
- NCT01840176
- Testing
- McCall culdoplasty
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Vaginal Vault Prolapse, Pelvic Floor Prolapse
Vaginal Vault Prolapse Surgical Treatment
Since apical support is the mainstay of vaginal cuff restoration, sacrocolpopexy is still accepted as the gold standard technique in vaginal vault prolapse (VVP).
- Trial name
- VVPST (NCT06792331)
- Testing
- vNOTES high uterosacral ligament suspension, Laparoscopic lateral suspension
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people
- Sponsor
- Sehit Prof. Dr. Ilhan Varank Sancaktepe Training and Research Hospital
Vault Prolapse, Vaginal
Comparison of PHVP of Different VTH Methods
To evaluate the post-hysterectomy vault prolapse (PHVP) rates performed using different methods of vaginal total hysterectomy (VTH).
- Trial name
- NCT03858673
- Testing
- VTH via the Tsuzi method with residual uterine ligament ligation
- Volunteers
- 213 people
- Sponsor
- National Taiwan University Hospital
Pelvic Organ Prolapse, Uterine Prolapse
Does a High BMI Affect Supervised Pelvic Floor Muscle Training for Improving Symptoms in Women With Various Stages of Pelvic Organ Prolapse?
The trial design is a quasi-experimental cohort trial that includes women referred for pelvic organ prolapse specific physiotherapy.
- Conditions
- Pelvic Organ Prolapse, Uterine Prolapse, Anterior Wall; Prolapse, Vaginal, Posterior Wall; Prolapse, Vaginal
- Trial name
- NCT04009694
- Testing
- Pelvic Floor Muscle training
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Salford
Gynecologic Cancers, Vaginal Cuff Dehiscence
Comparison of Self-Locking Versus Traditional Sutures in Double-Layer Laparoscopic Vaginal Vault Closure After Hysterectomy (BI-SURE Trial)
Vaginal vault closure after laparoscopic or robotic hysterectomy may be associated with postoperative complications such as vaginal cuff dehiscence, infection, and bleeding.
- Conditions
- Gynecologic Cancers, Vaginal Cuff Dehiscence, Postoperative Complications
- Trial name
- BI-SURE (NCT07313839)
- Testing
- Double-Layer Vaginal Vault Closure with Self-Locking Suture, Double-Layer Vaginal Vault Closure with Polyglactin 910
- Where
- 5 sites in Italy
- Volunteers
- 310 people
- Sponsor
- Azienda Ospedaliero-Universitaria di Parma
Visceral Prolapse
Apical Suspension Repair for Vault Prolapse In a Three-Arm Randomized Trial Design
The study is a multi-center, randomized, surgical trial of women with symptomatic post-hysterectomy apical (cuff) prolapse desiring surgical treatment.
- Trial name
- ASPIRe (NCT02676973)
- Testing
- Open, Robotic, or Laparoscopic, Transvaginal Native Tissue Repair, Uphold™ LITE
- Where
- 10 sites in United States
- Volunteers
- 360 people
- Sponsor
- NICHD Pelvic Floor Disorders Network
Vaginal Vault Prolapse, Uterine Prolapse
Laparoscopic Pectopexy and Laparoscopic Colporrhaphies in Pelvic Organ Prolapse Treatment
This prospective cohort study investigates the surgical outcomes of laparoscopic pectopexy and laparoscopic colporraphy performed at the Wellbeing Services County of South Ostrobothnia.
- Conditions
- Vaginal Vault Prolapse, Uterine Prolapse, Cystocele, Midline, Rectocele; Female
- Trial name
- NCT06902909
- Where
- Finland
- Volunteers
- 50 people
- Sponsor
- Tampere University Hospital
Urinary Incontinence, Stress, Mixed Incontinence
Treatment for Stress and Mixed Urinary Incontinence and Vaginal Vault Prolapse
The primary objective of this study is to further evaluate the safety and effectiveness of the use of a sling device in women for stress and mixed urinary incontinence as well as vaginal vault prolapse.
- Conditions
- Urinary Incontinence, Stress, Mixed Incontinence, Vaginal Vault Prolapse
- Trial name
- NCT00223106
- Testing
- Vaginal Sling
- Where
- United States
- Volunteers
- 467 people
- Sponsor
- Medtronic - MITG
Prolapse, Vaginal Vault
Transvaginal Mesh vs. Laparoscopic Colposacropexy- Study
The main objective of the study is to compare subjective efficacy of trans vaginal mesh and laparoscopic colposakropexy (CSP) in women with an apical prolapse.
- Trial name
- TVM vs LCSP (NCT04478747)
- Testing
- TVM, Colposacropexy
- Where
- Finland
- Volunteers
- 318 people, healthy volunteers welcome
- Sponsor
- Helsinki University Central Hospital
Pelvic Organ Prolapse
The Extended Operations And Pelvic Muscle Training In The Management Of Apical Support Loss Study
Women will be invited to participate in E-OPTIMAL at their last clinical follow-up visit for OPTIMAL (at 24 months post surgery).
- Trial name
- E-OPTIMAL (NCT01166373)
- Testing
- Enrollment video, SSLF, ULS
- Where
- 7 sites in United States
- Volunteers
- 285 people
- Sponsor
- NICHD Pelvic Floor Disorders Network
Nearsightedness
Vault Evaluation After ICL Implantation
The purpose of this study is to evaluate the lens vault after implantation of an implantable collamer lens (ICL). The ICL is designed to be implanted in front of the eye, without removing the natural lens.
- Trial name
- NCT06229119
- Testing
- Implantable Collamer Lens
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Carolina Eyecare Physicians, LLC
Cystocele, Vaginal Vault Prolapse
Laser Therapy in Managing Vaginal Prolapse
Efficacy of laser therapy in postmenopausal women with symptomatic prolapse stage >1. Assessment tools will include prolapse stage quantification system (POP-Q) and validated condition related questionnaires.
- Conditions
- Cystocele, Vaginal Vault Prolapse, Rectocele, Enterocele
- Trial name
- NCT03714607
- Testing
- Erbium Yttrium Aluminum Garnet (Er:YAG) laser
- Where
- Greece
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- National and Kapodistrian University of Athens
Edentulous Jaw
Intra Oral Scanning of Edentulous Arches
the aim of this study is to compare the influence of different palatal vault configurations on the accuracy and scan speed of IO scans in cases of completely edentulous arches.
- Trial name
- NCT06146153
- Testing
- digital impression
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- October University for Modern Sciences and Arts