Clinical trials: Vein Injury
Midline Catheter
Isometric Hand-Grip Exercise for Preventing Thrombosis and Occlusion of Midline Venous Catheters: A Randomized Controlled Trial
evaluate whether hand-grip ball exercises reduce thrombosis and occlusions of Midline catheters in hospitalized patients.
- Trial name
- NCT07654101
- Testing
- handgrip
- Volunteers
- 840 people
- Sponsor
- University Hospital Padova
Venous Stasis Ulcers
Provant Therapy of Venous Stasis Ulcer Trial
This pilot study hypothesizes that use of the Regenesis Provant Wound Therapy System (a radiofrequency device) twice daily over venous stasis ulcers (wounds thought to occur due to improper functioning of valves in the veins…
- Trial name
- NCT01050023
- Testing
- Provant Device (Wound Therapy System), Provant Device - Inactive
- Where
- 2 sites in United States
- Volunteers
- 25 people
- Sponsor
- Southern California Institute for Research and Education
Venous Leg Ulcer
Assessment of the Evolution of Wound Biomarkers in Venous Leg Ulcers Treated With KLOX Biophotonic System
The main purpose of the study is to evaluate the effect of KLOX BioPhotonic System (composed of KLOX LumiHeal Gel and KT-L Lamp) on the expression of wound biomarkers in the treatment of venous leg ulcers (VLU).
- Trial name
- NCT03593369
- Testing
- KLOX BioPhotonic System (single treatment)+SOC, KLOX BioPhotonic System (consecutive treatments)+SOC, Standard of Care (SOC)
- Where
- Italy
- Volunteers
- 25 people
- Sponsor
- KLOX Technologies Inc.
Wound of Skin
Efficacy of Prophylactic Negative Pressure Wound Therapy (NPWT)
The role of prophylactic negative pressure wound therapy (NPWT) is promising in reducing wound-related complications. However, the prophylactic use of NPWT in reducing wound complications in patients who underwent conventional…
- Trial name
- EFESO (NCT05727995)
- Testing
- PICO7, usual care dressing
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- IRCCS Policlinico S. Donato
Wounds
Positive Predictive Value of the MolecuLight i:X Imaging Device to Predict the Presence of Bacteria in Chronic Wounds
This is a non-randomized evaluation for which 50 patients will be imaged at the Southwest Regional Wound Care Center, Lubbock, Texas, who present with a chronic wound and are receiving standard treatment.
- Trial name
- NCT02682069
- Testing
- MolecuLight i:X Imaging Device
- Volunteers
- 30 people
- Sponsor
- MolecuLight Inc.
Atrial Fibrillation (AF), Atrial Fibrillation Ablation Procedure
Efficacy and Safety of a Voltage-Guided Stepwise Strategy for Pulmonary Vein Isolation
The goal of this clinical trial is to learn if a voltage-guided stepwise pulmonary vein isolation (PVI) strategy can achieve effective PVI while potentially reducing lesion delivery, compared with conventional circumferential…
- Conditions
- Atrial Fibrillation (AF), Atrial Fibrillation Ablation Procedure, Atrial Tachyarrhythmia Recurrence, Esophageal Thermal Injury
- Trial name
- VoS-PVI (NCT07354737)
- Testing
- Radiofrequency ablation catheter system
- Where
- South Korea
- Volunteers
- 130 people
- Sponsor
- Ajou University School of Medicine
VTE (Venous Thromboembolism), Phantom Limb Pain After Amputation
Venous Thromboembolism and Chronic Pain After Major Limb Trauma
Major limb trauma is associated with a high risk of venous thromboembolism (VTE) due to systemic inflammation, endothelial injury, immobilization, and hypercoagulability.
- Conditions
- VTE (Venous Thromboembolism), Phantom Limb Pain After Amputation, Chronic Pain, Chronic Pain Due to Injury
- Trial name
- THROMBO-PAIN (NCT07475910)
- Where
- Ukraine
- Volunteers
- 150 people
- Sponsor
- Charitable Organisation Charitable Fund Superhumans (Co Cf Superhumans)
Septic Shock
Effect of Fluid Deresuscitation With Central Venous Pressure Target 0-4 mmHg in Septic Shock Patients
A scientific research to prove the safety and effectiveness of TVS 0 - 4 mmHg as a target of resuscitation using furosemide, to improve Perfused Vessel Density (PVD) > 25 mm / mm2, AKI stage (based on KDIGO criteria), CI > 2.5 cc…
- Trial name
- NCT04156451
- Testing
- Fluid resuscitation and furosemide administration (bolus and continuous) with central venous pressure target 8 - 10 mmHg, Fluid deresuscitation and furosemide administration (bolus and continuous) with central venous pressure target 0 - 4 mmHg
- Where
- Indonesia
- Volunteers
- 44 people
- Sponsor
- Universitas Indonesia
Acute Kidney Injury, Continuous Renal Replacement Therapy
Continuous Veno-venous Hemodialysis and Continuous Veno-venous Hemodiafiltration on Urea Reduction Rate in Intensive Care Patient
In patients requiring renal replacement therapy (RRT) in the intensive care unit (ICU), continuous techniques are predominantly using due to better hemodynamic tolerance.
- Conditions
- Acute Kidney Injury, Continuous Renal Replacement Therapy, Intensive Care Unit
- Trial name
- CompEER (NCT06369064)
- Testing
- CVVHD Dialysis parameters, CVVHDF Dialysis parameters
- Where
- France
- Volunteers
- 80 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Stroke, Acute Stroke
Stroke and Cerebrovascular Diseases Registry
This is a single institutional registry database for the patients with stroke and cerebrovascular diseases. Stroke is the fifth leading cause of death in the United States.
- Conditions
- Stroke, Acute Stroke, Acute Brain Injury, Ischemic Stroke
- Trial name
- NCT03281590
- Where
- United States
- Volunteers
- 4,594 people, healthy volunteers welcome
- Sponsor
- University of New Mexico
Wounds and Injuries, Burns
ACTICOAT™ for the Treatment of Burns and Chronic Wounds
The aim of the study is to evaluate participant reported quality of life, safety, and overall performance with ACTICOAT in a clinical setting.
- Conditions
- Wounds and Injuries, Burns, Pressure Ulcer, Foot Ulcer
- Trial name
- NCT02852148
- Testing
- ACTICOAT
- Where
- 3 sites in United Kingdom
- Volunteers
- 25 people
- Sponsor
- Smith & Nephew, Inc.
Acute Kidney Injury
Continuous Central Venous Oxygen Saturation Measurement as a Tool to Predict Hemodynamic Instability Related to Renal Replacement Therapy in Critically Ill Patients
Acute kidney injury (AKI) is common in intensive care unit (ICU) and inducing a high morbidity and mortality. In severe forms of AKI (more than 25% of AKI patients admitted to the ICU), renal replacement therapy (RRT) is often…
- Trial name
- SoVHIRR (NCT05897840)
- Testing
- Fiber-optic probe CeVOX
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Montpellier
Diabetic Foot Ulcer, Pressure Ulcer
A Prospective, Open Label, Multicenter Trial for Evaluating the Efficacy of Treating and Managing Wounds in Elderly Population in Specialized Nursing Facilities Using RD1
The study is a prospective, single arm, multicenter efficacy study, consisting of 60 subjects who will complete the study (note: if any patients are lost to follow-up or withdrawn, enrollment will increase to compensate for loss…
- Conditions
- Diabetic Foot Ulcer, Pressure Ulcer, Venous Leg Ulcer, Trauma Injury
- Trial name
- NCT04577183
- Testing
- RD1 System
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- RedDress Ltd.
Venous Thromboembolic Disease, Deep Vein Thrombosis
Venous Thromboembolic Prophylaxis After Trauma: Three Times a Day Unfractionated Heparin Versus Twice a Day Enoxaparin
The rate of venous thromboembolic events in trauma patients at high risk for deep vein thrombosis and pulmonary embolism receiving low dose unfractionated heparin every 8 hours will be equivalent or less than a similar group of…
- Conditions
- Venous Thromboembolic Disease, Deep Vein Thrombosis, Pulmonary Embolism
- Trial name
- NCT01729559
- Testing
- 5000 Units unfractionated Heparin Q 8 hr, 30mg enoxaparin Q12 hr
- Where
- United States
- Volunteers
- 495 people
- Sponsor
- Scripps Health
Acute Kidney Injury, Chronic Kidney Disease Stage 5 on Dialysis
Non-invasive Assessment to Predict Tolerance to Fluid Removal on Intermittent Kidney Replacement Therapy
This prospective cohort study aim to investigate the ability of multiple types of assessments including 1) the modified Venous Excess Ultrasound (VExUS) assessment, 2) non-invasive estimation of absolute blood volume (ABV), and…
- Conditions
- Acute Kidney Injury, Chronic Kidney Disease Stage 5 on Dialysis, Chronic Kidney Failure, Intradialytic Hypotension
- Trial name
- TECHNO-HDF (NCT05270759)
- Testing
- Estimated absolute blood volume, Modified VExUS evaluation
- Where
- Canada
- Volunteers
- 93 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Venous Ulcers
Effect of Compressive Therapies on the Healing of Venous Ulcers
The objective of the study is to compare the effect of two treatments on the healing of venous ulcers in follow-up people in two Primary Health Services, in a city in southern Brazil.
- Trial name
- VENOS (NCT04703569)
- Testing
- Dressing with monolayer high compression elastic bandage, Dressing with Unna boot
- Where
- 3 sites in Brazil
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Hospital de Clinicas de Porto Alegre
Leg Ulcer, Varicose Ulcer
Evaluation of Safety and Activity of Celaderm in Healing Venous Leg Ulcers
This pilot study was designed to test the safety of Celaderm(TM) in treating venous leg ulcers and to give preliminary information about the efficacy of two different Celaderm(TM) dosing regimens.
- Trial name
- NCT00399308
- Testing
- Celaderm (Frozen Cultured Epidermal Allograft), Control (compression bandaging)
- Where
- 9 sites in United States
- Volunteers
- 40 people
- Sponsor
- Shire
Lower Extremity, Chronic Ulcers
Evaluating Autologous Platelet-Rich Fibrin Plasma for Chronic Lower Extremity Ulcers
To prospectively evaluate the safety and efficacy of an Autologous Platelet-Rich Fibrin Plasma system when applied in conjunction with Standard of Care for management of chronic lower extremity wounds.
- Conditions
- Lower Extremity, Chronic Ulcers, Pressure Ulcer (PU), Venous Leg Ulcer (VLU)
- Trial name
- NCT07862335
- Testing
- PRFM
- Volunteers
- 30 people
- Sponsor
- Tiger Biosciences, LLC.
Wounds and Injuries, Venous Leg Ulcer
DURAFIBER Ag Post-Market Clinical Follow-Up
The aim of the study is to evaluate the performance of DURAFIBER Ag and to assess how many bacteria are present in infected wounds over an 8 week period.
- Conditions
- Wounds and Injuries, Venous Leg Ulcer, Infection
- Trial name
- NCT03277131
- Testing
- DURAFIBER Ag
- Where
- 7 sites in United Kingdom
- Volunteers
- 20 people
- Sponsor
- Smith & Nephew, Inc.
Venous Insufficiency, Diabetes
Evaluation of DermStream(tm) - an Irrigation Product for Chronic Wound Management
The primary purpose of this study is to evaluate the safety of DermaStream(tm) in the management of chronic wounds. Other goals of this study are to gain feedback from patients and healthcare providers on the ease of use (the…
- Trial name
- NCT00310752
- Testing
- DermaStream(tm) application and Streaming of Saline
- Where
- Israel
- Volunteers
- 11 people
- Sponsor
- EnzySurge