Clinical trials: Venous
Varicose Veins
Endoveneous Histologic Study
A new technique, mechanochemical endovenous ablation (MOCA), using the ClariVein ® system is recently developed. To date, histopathological data after mechanochemical endovenous ablation are not known.
- Trial name
- NCT03326219
- Testing
- Clarivein
- Where
- Netherlands
- Sponsor
- Rijnstate Hospital
Right Ventricular Dysfunction
Right Ventricular Function Changes After CIED Implantation: The RIGHT-CIED Study
This study aims to understand how the right side of the heart changes in people who receive an implantable cardiac electronic device (CIED), such as a pacemaker, ICD, or CRT device.
- Trial name
- RIGHT-CIED (NCT07272395)
- Testing
- Multimodal Right Ventricular Evaluation
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Istanbul University - Cerrahpasa
Venous Congestion, Postoperative Care
Portal and Splenic Venous Pulsatility in Postoperative Critically Ill Patients
Venous congestion is common in critically ill postoperative patients and may be associated with adverse outcomes. Doppler ultrasound assessment of venous flow patterns, including portal venous pulsatility, is increasingly used to…
- Trial name
- PULSE-ICU (NCT07826481)
- Volunteers
- 60 people
- Sponsor
- Hospital Universitario de Gran Canaria Doctor Negrín
Atrial Fibrillation
Comparison of Externally Versus Internally Cooled Tip Catheter Ablation in Paroxysmal Atrial Fibrillation
There is no study comparing safety/efficacy of externally vs internally cooled tip catheters in patients undergoing ablation for paroxysmal atrial fibrillation (pAF).
- Trial name
- CATAFABL (NCT00816192)
- Testing
- Long-term electrical isolation of pulmonary veins
- Where
- 2 sites in France
- Volunteers
- 86 people
- Sponsor
- University Hospital, Bordeaux
Atrial Fibrillation (AF)
Feasibility, Safety, Cost-effectiveness, and Environmental Impact of Reprocessed Ablation Catheters in PVI
This study evaluates whether re-sterilized (reprocessed) ablation catheters are as effective and safe as new ablation catheters when used for pulmonary vein isolation in patients with atrial fibrillation.
- Trial name
- RE-USE PVI (NCT07389434)
- Testing
- Participants will undergo pulmonary vein isolation using pulsed field ablation (PFA). The intervention consists of the use of either a reprocessed electroporation ablation catheter or a new electropor
- Where
- Croatia
- Volunteers
- 200 people
- Sponsor
- University Hospital Dubrava
Retinal Vein Occlusion, Macular Edema
Efficacy and Safety of Lucentis for Clinically Significant Macular Edema Secondary to Central Retinal Vein Occlusion
This study aims to assess if Lucentis injection applied into the eye is superior to conventional treatment concerning the prevention of visual loss in patients having clinically significant macular edema secondary to retinal vein…
- Trial name
- BRAVO (NCT01123564)
- Testing
- ranibizumab, Argon laser treatment
- Where
- 2 sites in Hungary
- Volunteers
- 40 people
- Sponsor
- University of Pecs
Vascular Malformation, Arteriovenous Malformation
Diagnostic Imaging of Vascular Malformations Using MSOT and ULM
This clinical study evaluates the efficacy and accuracy of Multispectral Optoacoustic Tomography (MSOT) and Ultrasound Localization Microscopy (ULM) for imaging and diagnosing vascular malformations (venous, arteriovenous…
- Conditions
- Vascular Malformation, Arteriovenous Malformation, Lymphatic Malformation, Venous Malformations
- Trial name
- NCT06994260
- Testing
- Multispectral Optoacoustic Tomography, Ultrasound Localization Microscopy
- Where
- Germany
- Volunteers
- 15 people
- Sponsor
- University Hospital Erlangen
Venous Thrombosis, Pediatrics
Rivaroxaban Pharmacokinetics/Pharmacodynamics (PK/PD) Study in Pediatric Subjects
The first study with rivaroxaban in pediatric subjects is a Phase I study, where the pharmacokinetic/pharmacodynamic (PK/PD) profile of rivaroxaban will be investigated to confirm that the exposure is comparable to adults.
- Trial name
- NCT01145859
- Testing
- Rivaroxaban (Xarelto, BAY59-7939)
- Where
- 36 sites in United States, Australia and 8 more
- Volunteers
- 59 people
- Sponsor
- Bayer
Hard to Heal Wounds, Venous Leg Ulcers
Efficacy and Safety Study of EscharEx to Treat (Debride) Hard to Heal Wounds
The main objective of this study is to assess the safety and the efficacy of EscharEx in preparing the wound's bed in patients with hard to heal venous leg ulcers, diabetic lower extremity ulcers and traumatic/post operative…
- Conditions
- Hard to Heal Wounds, Venous Leg Ulcers, Diabetic Lower Extremity Ulcers, Traumatic/ Post Operative Wounds
- Trial name
- NCT02020746
- Testing
- EscharEx, Gel Vehicle
- Where
- 8 sites in Israel
- Volunteers
- 111 people
- Sponsor
- MediWound Ltd
Atrial Fibrillation, Thrombus Due to Heart Valve Prosthesis
The Effect of Medication Timing on Anticoagulation Stability in Users of Warfarin: The "INRange" RCT
Warfarin is an anticoagulant medication that is highly effective at preventing clotting disorders but which has a narrow therapeutic window.
- Conditions
- Atrial Fibrillation, Thrombus Due to Heart Valve Prosthesis, Deep Venous Thrombosis, Thromboembolism
- Trial name
- NCT02376803
- Testing
- Warfarin
- Where
- 2 sites in Canada
- Volunteers
- 217 people
- Sponsor
- University of Alberta
Leg Ulcers, Varicose Ulcers
Legtest Multi Centre Testing of the Lively Legs Program for Promoting Compliance in Leg Ulcer Patients
Leg ulcers are often chronic or recurring complications of peripheral circulation disorders. Patients' lifestyles are known to influence leg ulcer occurrence and circulation disorders in general.
- Trial name
- NCT00184873
- Testing
- Health Counseling
- Where
- 11 sites in Netherlands
- Volunteers
- 180 people
- Sponsor
- Radboud University Medical Center
Venous Malformations, Lymphatic Malformations
A Study to Investigate Efficacy and Safety of KP-001 Compared With Placebo in Patients Aged ≥2 Years With Common VM, Common LM, or KTS/CLOVES Syndrome
This is a phase 3, double-blind, randomized, placebo-controlled, parallel group, adaptive, multicenter study planned to be conducted at multiple sites in North America, Canada, Taiwan and South Korea.
- Conditions
- Venous Malformations, Lymphatic Malformations, Klippel-Trenaunay Syndrome, CLOVES Syndrome
- Trial name
- S-KY (NCT07285005)
- Testing
- KP-001
- Where
- 5 sites in United States, South Korea and 1 more
- Volunteers
- 150 people
- Sponsor
- Kaken Pharmaceutical
Venous Thrombosis
A Study of MK-2060 in Healthy Participants (MK-2060-016)
The goal of the study is to learn about the safety of MK-2060 and if people tolerate it when MK-2060 is given in different forms.
- Trial name
- NCT06582602
- Testing
- MK-2060
- Where
- 2 sites in United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
Pelvic Congestive Syndrome
Embolization Strategies for Pelvic Venous Disorders: Foam + Glue vs Foam + Coils
Foam Plus Glue Versus Foam Plus Coils for Ovarian Vein Embolization in the Treatment of Pelvic Venous Disorders: A Randomized Controlled Trial
- Trial name
- foam and coil (NCT07221695)
- Testing
- Foam + N-butyl Cyanoacrylate, Combined Foam Sclerotherapy and Detachable Coil Embolization
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Kafrelsheikh University
Venous Thromboembolism
Identification of New Genetic Markers of Risk of Venous Thromboembolism Recurrence by Analyzing Whole Genome
Venous thromboembolism (VTE) is a common and potentially fatal disease. It is considered a chronic disease with a recurrence rate of 30% at 10 years. Reduce the risk of recurrence is a serious public health issue.
- Trial name
- NCT02904967
- Testing
- Extra Blood Draw
- Where
- France
- Volunteers
- 221 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Venous Leg Ulcer
A Study to Evaluate the Safety and the Efficacy of EscharEx (EX-02 Formulation) in Debridement of Venous Leg Ulcers
This study is a multicenter, prospective, randomized, placebo controlled, adaptive design study performed to assess the safety and the efficacy of 5% EscharEx (EX-02) compared to Gel Vehicle (placebo) and non-surgical standard of…
- Trial name
- NCT03588130
- Testing
- EscharEx (5% EX-02 formulation), Gel Vehicle, Non-surgical standard of care (NSSOC)
- Where
- 22 sites in United States, Switzerland
- Volunteers
- 120 people
- Sponsor
- MediWound Ltd
Chronic Venous Disease
Ruscus Evaluation for Symptom Control in Uncomplicated Chronic Venous Insufficiency
This multicenter, prospective, observational study aims to generate and analyze real-world data on the effectiveness and safety of Ruscus aculeatus L.
- Trial name
- RESCUE-CVI (NCT07737236)
- Where
- 25 sites in Turkey (Türkiye)
- Volunteers
- 564 people
- Sponsor
- Turkish Society for Vascular and Endovascular Surgery
Phlebitis
Peripheral Venous Catheter Trial: 3 Day Versus No Routine Change
The purpose of this study is to investigate the effects of extending the dwell time of peripheral intravenous cannulas on clinical outcomes and cost.
- Trial name
- NCT00103636
- Testing
- Extending peripheral intravenous (IV) cannula dwell times
- Where
- Australia
- Volunteers
- 200 people
- Sponsor
- Royal Brisbane and Women's Hospital
Pulmonary Arterial Hypertension
Long-term Extension Study of the Safety and Pharmacokinetics of QCC374 in PAH Patients
This is a long-term open-label safety extension to the Phase 2a study of inhaled QCC374 in adult patients with PAH. This study provides the patients who completed the QCC374X2201 study with the option to continue receiving…
- Trial name
- NCT02939599
- Testing
- QCC374
- Where
- 4 sites in United States, Germany and 1 more
- Volunteers
- 5 people
- Sponsor
- Novartis Pharmaceuticals
Physiologic Venous Dilation, Air Travel
Randomized Assessor-Masked Trial of Moderate Graduated Compression Stockings for Popliteal Vein Dilation During Long-Haul Economy-Class Air Travel After Aesthetic Surgery
This randomized assessor-masked trial will evaluate whether knee-high moderate graduated compression stockings reduce popliteal vein dilation during long-haul economy-class air travel to Bogota.
- Trial name
- NCT07810192
- Testing
- Enoxaparine, Knee-High Graduated Compression Stockings, Standardized Bilateral Popliteal Vein Ultrasound
- Where
- Colombia
- Volunteers
- 160 people
- Sponsor
- Research Inc
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.