Clinical trials: Venous
Thromboembolism in the Puerperium
Safety of Fondaparinux as Post Partum Thromboprophylaxis
Venous thromboembolism (VTE) remains as one of leading causes of maternal morbidity and mortality, with postpartum period carries the greatest risk.
- Trial name
- NCT04447378
- Testing
- Fondaparinux 2.5Mg/0.5Ml Inj Syr
- Where
- Malaysia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- National University of Malaysia
Cardiac Surgery
The Effect of Simple Needle Guide Device for Ultrasound-guided Internal Jugular Vein Catheterization in Cardiac Surgical Patients
The purpose of this study is to evaluate the effect of simple needle guide device for ultrasound-guided internal jugular vein catheterization in cardiac surgical patients
- Trial name
- NCT03390543
- Testing
- Sono with Device, sono only
- Where
- South Korea
- Sponsor
- Yonsei University
Hepatocellular Carcinoma
Perioperative Sintilimab Plus Bevacizumab Biosimilar and TACE-HAIC for HCC Patients With PVTT: A Phase-2 Clinical Trial
Although resection provided survival benefit for selected HCC patients with PVTT, the recurrence rate is still high for those patients.
- Trial name
- NCT06031285
- Testing
- Sintilimab
- Where
- China
- Volunteers
- 43 people
- Sponsor
- Sun Yat-sen University
Malaria
Lumefantrine in Venous Plasma Versus Dried Capillary Blood Spot
Measurement of the concentration of antimalarials in the blood of the general population helps estimating the overall drug pressure and is used in efficacy studies.
- Trial name
- NCT02742285
- Testing
- Artemether + lumefantrine
- Where
- Switzerland
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Thierry Buclin
Pregnancy
Portal Vein Pulsatility Flow in Pregnancy
This study is to investigate if portal vein pulsatility fraction can be measured in pregnancy and if it increases during the course of pregnancy as would be expected by the physiologic increase in blood volume that happens during…
- Trial name
- NCT04429178
- Testing
- ultrasound
- Where
- Switzerland
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Acute Kidney Injury, Covid19
CoV-Hep Study: Regional Anticoagulation Modalities in Continuous Venous Venous Hemodialysis in Patients With COVID-19
Since the emergence of the new strain of betacoronavirus (SARS-CoV-2) and its important clinical repercussions, it has been described that patients with its associated pneumonia (COVID-19) have high rates of thrombotic events…
- Trial name
- NCT04487990
- Testing
- unfractionated Heparin
- Where
- Brazil
- Volunteers
- 118 people
- Sponsor
- University of Sao Paulo General Hospital
Brachiocephalic Vein Stenosis
Biomimetic Stent and Drug Eluting Balloon to Treat Recurrent Cephalic Arch Stenosis
The study evaluates the use of a biomimetic stent (SUPERA®) and a drug eluting balloon (DEB - Passeo 18 Lux) for the treatment of recurrent and tight cephalic arch stenosis in patients with brachiocephalic fistulas.
- Trial name
- Arch-V (NCT03891693)
- Testing
- Passeo-18 Lux and SUPERA® stent
- Where
- Singapore
- Volunteers
- 20 people
- Sponsor
- Singapore General Hospital
Heart Surgery
Negative Venous Line Pressure in a Miniaturised Cardiopulmonary Bypass Circuit (CPB)
Study to measure the ability of a 'fenestrated' venous line cannula to reduce the negative line pressure seen with kinetic-assist active venous drainage (KAVD) in a standard miniaturised cardiopulmonary bypass circuit and thereby…
- Trial name
- NCT03717649
- Testing
- Conventional 2-stage venous cannula, Conventional 3-stage venous cannula, Fenestrated 3-stage venous cannula
- Volunteers
- 48 people
- Sponsor
- University Hospital Plymouth NHS Trust
Pulmonary Embolism, Venous Thromboembolism
Celect Vena Cava Filter Clinical Trial
The clinical study will collect data to verify the safety and performance of the Cook Celect Filter in the prevention of pulmonary embolism (PE) in patients with a temporary or permanent high risk of thromboembolism.
- Trial name
- NCT00470626
- Testing
- Celect Vena Cava Filter
- Where
- 8 sites in Australia, Germany and 3 more
- Volunteers
- 129 people
- Sponsor
- Cook Group Incorporated
Liver Cirrhosis Due to Virus C Chronic Hepatitis
Autologous Bone Marrow Mononuclear Cells in Liver Cirrhosis
This is a phase I clinical study to evaluate feasibility, safety and kinetics of cellular therapy with autologous bone marrow-derived mononuclear cells (BMMC) in patients with liver cirrhosis due to virus C hepatitis.
- Trial name
- CELTHEP-02 (NCT00832247)
- Testing
- Autologous bone marrow mononuclear cells infusion
- Where
- Brazil
- Volunteers
- 15 people
- Sponsor
- Universidade Federal do Rio de Janeiro
Macular Edema Secondary to Branch Retinal Vein Occlusion (BRVO)
Study to Show a Superior Benefit in Terms of Reduction of Ranibizumab Injections in Patients Receiving Ranibizumab Plus Laser Photocoagulation Combination Therapy Without Loss of Efficacy and Safety
This is a Phase IV, randomized, open-label, active-controlled, 2-arm, multicenter study. The primary objective was assessed by the difference in the mean number of ranibizumab injections applied up to Month 11 between the 2…
- Trial name
- ZIPANGU (NCT02953938)
- Testing
- Ranibizumab, Grid&Direct short pulse laser photocoagulation
- Where
- 7 sites in Japan
- Volunteers
- 59 people
- Sponsor
- Novartis Pharmaceuticals
Wounds and Injuries, Burns
ACTICOAT™ for the Treatment of Burns and Chronic Wounds
The aim of the study is to evaluate participant reported quality of life, safety, and overall performance with ACTICOAT in a clinical setting.
- Conditions
- Wounds and Injuries, Burns, Pressure Ulcer, Foot Ulcer
- Trial name
- NCT02852148
- Testing
- ACTICOAT
- Where
- 3 sites in United Kingdom
- Volunteers
- 25 people
- Sponsor
- Smith & Nephew, Inc.
Anxiety, Pain
Musical Intervention and Patient's Anxiety During Central Venous Catheter Insertion in the Intensive Care Unit
Intensive care unit patients who have to undergo central venous catheter insertion and are able to hear explanations and to gave consent, will be randomized to either usual care during catheter insertion or to a musical…
- Trial name
- MUSIC-CAT (NCT03398525)
- Testing
- usual care, Musical intervention
- Where
- France
- Volunteers
- 75 people
- Sponsor
- Centre Hospitalier Régional d'Orléans
Cervical Cancer
Radiation Therapy With or Without Cisplatin or Fluorouracil in Treating Patients With Cancer of the Cervix
RATIONALE: Radiation therapy uses high-energy x-rays to damage tumor cells. Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die.
- Trial name
- NCT00003078
- Testing
- cisplatin, fluorouracil, brachytherapy
- Where
- 66 sites in United States, Canada
- Volunteers
- 870 people
- Sponsor
- Gynecologic Oncology Group
Cancer, Venous Thromboembolism
Cancer Patients Diagnosed With Unsuspected Venous Thromboembolism (VTE) on Routine Computed Tomography (CT) Scans
This is a prospective study with the following objectives: Primary Objective: 1. To estimate the prevalence of unsuspected VTE in oncology patients on routine staging CT scans of the thorax, abdomen and pelvis.
- Trial name
- NCT00925808
- Testing
- Questionnaires
- Where
- United States
- Volunteers
- 1,187 people
- Sponsor
- M.D. Anderson Cancer Center
Ultrasound-Guided Vascular Access, ICU Patients
Ultrasound-Guided BCV and IJV in ICU Patients
This is a prospective randomized clinical trial aiming to compare the success rate, complications, and insertion time between ultrasound-guided brachiocephalic vein (BCV) and internal jugular vein (IJV) cannulation in…
- Trial name
- NCT07062068
- Testing
- ultrasound guided Brachiocephalic vein and internal jugular vein cannulation in mechanically ventilated ICU patients
- Volunteers
- 100 people
- Sponsor
- Sohag University
Venous Stasis Ulcers
Wound Fluid Protease Levels During Use of Novel Wound Dressing
This study is being conducted to characterize the way leg wounds respond to a new type of wound dressing, compared to wounds in patients who are not using the new dressing.
- Trial name
- NCT01567150
- Testing
- Novel Dressing
- Where
- 8 sites in United States
- Volunteers
- 35 people
- Sponsor
- Hollister Incorporated
Venous Disease, Varicose Veins
Great Saphenous Vein Electrocoagulation
Introduction: Lower extremity Chronic Venous Insufficiency is a prevalent disease that adversely affects an individual's Quality of Life.
- Trial name
- NCT02139085
- Testing
- GSV Electrocoagulation, GSV Radiofrequency
- Where
- Brazil
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Instituto Dante Pazzanese de Cardiologia
Baker's Cyst
Focused Ultrasound of the Popliteal Fossa for Detection of Symptomatic Baker's Cysts in Patients With Suspected Deep Vein Thrombosis: A Pilot Diagnostic Accuracy Study
Quality improvement study with prospective observational design. The study explores the feasibility of testing diagnostic accuracy of an emergency department-performed focused ultrasound scan of the popliteal fossa in detecting…
- Trial name
- BAKER-DVT (NCT07791017)
- Testing
- Index Test (Focused Ultrasound of the Popliteal Fossa), Reference test (Routine DVT Diagnostic Pathway)
- Where
- Denmark
- Volunteers
- 94 people
- Sponsor
- Aarhus University Hospital
Pain Management, Fear and Anxiety
Virtual Reality for Pain, Fear, and Physiological Responses During Pediatric Venous Catheterization
This study aims to evaluate the effect of two different virtual reality (VR) applications on children's pain, fear, and physiological parameters during peripheral intravenous catheterization.
- Trial name
- VR-PainKids (NCT07202468)
- Testing
- Virtual Reality
- Volunteers
- 150 people
- Sponsor
- Ege University
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