Clinical trials: Venous Insufficiency of Leg
Chronic Venous Disease, Vein Disease
Randomized, Placebo-crontrolled Clinical Trial Evaluating the Efficacy and Safety of Heparan Sulfate 120 mg Prolonged-Release Tablets Compared With Placebo in Patients With Chronic Venous Disease
This multicenter, randomized, double-blind study is a phase III evaluates the safety and effectiveness of CLR prolonged-release tablets in patients with chronic venous insufficiency, has been shown to be effective in reducing the…
- Conditions
- Chronic Venous Disease, Vein Disease, Venous Insufficiency of Leg
- Trial name
- CLR-18 (NCT07684833)
- Testing
- CLR Tablets - Heparan Sulphate
- Volunteers
- 174 people, healthy volunteers welcome
- Sponsor
- Barbara Maglione
Lymphedema, Chronic Venous Insufficiency
A Non-randomized, Open-Label Study to Evaluate the Safety and Effectiveness of Insight® Pro Device for Evaluating Lymphatic and Venous Disorders (VOLGA)
To demonstrate that the Insight Pro Device is safe and effective for use in detecting lymphatic and venous disorders.
- Conditions
- Lymphedema, Chronic Venous Insufficiency, Edema, Venous Insufficiency of Leg
- Trial name
- VOLGA (NCT05628688)
- Testing
- Insight Pro Device for Diagnosis
- Where
- United States
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Koya Medical, Inc.
Varicose Veins, Venous Insufficiency
The Party Balloon Assisted Valsalva in Diagnosis of Superficial Venous Valvular Reflux of Lower Limb
This study was designed to compare the party balloon assisted Valsalva with the conventional Valsava for exhibiting the reverse venous flow in superficial venous valvular incompetence duplex examination.
- Trial name
- NCT02051439
- Testing
- Valsava
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Varicose Veins of Lower Limb, Thromboses, Venous
Prospective Cohort Study for Varicose Veins Incidence and Natural Course
A prospective study of individuals without varicose veins and who have primary varicose veins to assess the morbidity, risk factors and natural course of chronic lower limb vein disease.
- Conditions
- Varicose Veins of Lower Limb, Thromboses, Venous, Venous Insufficiency
- Trial name
- VINCI (NCT04546750)
- Where
- Russia
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Russian Phlebological Association
Venous Leg Ulcer
DEep VEin Lesion OPtimisation (DEVELOP) Trial
This is a prospective, single centre, randomised controlled, feasibility study recruiting patients with lower limb venous ulceration and Great Saphenous incompetence.
- Trial name
- Develop (NCT03640689)
- Testing
- Endovenous ablation + iliac US +/- iliac stenting, Endovenous ablation of Great Saphenous Vein
- Where
- 2 sites in Ireland
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- National University of Ireland, Galway, Ireland
Venous Insufficiency
Non-Invasive Management of Chronic Venous Insufficiency
The purpose of this study is: -item one to use two new non-invasive technologies to evaluate scarring and swelling associated with chronic venous insufficiency.
- Trial name
- NCT00950378
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Utah
Venous Leg Ulcer, Venous Insufficiency of Leg
Preliminary Investigation of a Smart Compression Therapy Prototype
Compression wraps treat venous leg ulcers when applied correctly. Often, clinicians apply the wraps at the wrong compression, or the wrap loosens, stopping clinical benefits.
- Trial name
- PRESUF-VLU (NCT05610241)
- Testing
- Compression Therapy System Prototype, Standard Compression
- Where
- Ireland
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- DeRoyal Industries, Inc.
Varicose Veins, Varicose Veins of Lower Limb
The Evaluation of the Pathophysiology of Varicose Veins in Pregnancy
Varicose veins (VV) are the early sign of Chronic venous insufficiency (CVI) which are characterised by abnormal tortuosity and dilatation of superficial veins of lower limb extremities.
- Conditions
- Varicose Veins, Varicose Veins of Lower Limb, Chronic Venous Insufficiency, Varicose; Vessel
- Trial name
- NCT05058989
- Testing
- Advanced ultrasound measurements (Duplex ultrasound (DUS) and Vector flow imaging (VFI), Clinical interventions and procedures
- Where
- United Kingdom
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Edema Leg, Venous Insufficiency of Leg
Discovering the Effect of Venous Insufficiency on Nocturia (DEVINe)
Nocturia, or waking during the night to pass urine, is a multifactorial disease. An important cause of nocturia are peripheral edema due to accumulation of fluid in the lower limbs.
- Conditions
- Edema Leg, Venous Insufficiency of Leg, Nocturia, Bio-Impedance Measurements
- Trial name
- DEVINe Pilot (NCT03928197)
- Testing
- Tilt Test, Inbody S10, Tape measurements
- Where
- Belgium
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent
Venous Insufficiency
Effectiveness of a Pressure Indicator Guided and a Conventional Bandaging in Treatment of Venous Leg Ulcer
Objective of this study are to compare the interface pressure by applying ordinary elastic bandage (OEB) and CPG-EB. In addition, investigators compared the percentage of patients who could apply the optimal pressure with OEB and…
- Trial name
- NCT02729688
- Testing
- customized pressure guide bandage, Ordinary elastic bandage
- Where
- Thailand
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Varicose Veins, Venous Reflux
Comparison of Zero- and Two-centimeter Distance From Sapheno-femoral Junction in Laser Ablation of Varicose Vein
EVLA is used in in treating refluxing veins, commonly the GSV. The tip of catheter is usually placed 2-2.5 cm distal to the sapheno-femoral junction.
- Conditions
- Varicose Veins, Venous Reflux, Venous Insufficiency, Venous Leg Ulcer
- Trial name
- NCT05707169
- Testing
- Saphenous Ablation, Endogenous Laser Ablation (EVLA), mixture of 20 mL 2% lidocaine, 1: 200,000 adrenaline and 20 mL 0.5% levobupivacaine in 1 L of 0.9% saline
- Where
- Egypt
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Venous Insufficiency of Leg, Venous Leg Ulcer
Non Contrast MRI in Lower Extremity
We collected retrospectively the non contrast MRI in chia yi memorial hospital for different venous disease of lower extremity morphology and flow ananlysis were done.
- Conditions
- Venous Insufficiency of Leg, Venous Leg Ulcer, Venous Occlusion, Contrast Media Reaction
- Trial name
- NCT04995432
- Where
- Taiwan
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Varicose Ulcer, Venous Insufficiency of Leg
Utilization of Compreflex Wraps in Patients With Chronic Venous Insuffciency
This is a multicentre, quasi-experimental study to evaluate the Conformitè Europëenne-marked Compreflex standard calf and foot (with basic liner) under routine conditions.
- Trial name
- NCT05364112
- Testing
- Compreflex
- Where
- Malaysia
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Kuala Lumpur General Hospital