Clinical trials: Venous Thrombosis (Disorder)
Hepatocellular Carcinoma
HAIC of FOLFOX vs. HAIC of OXA for Advanced HCC
The purpose of this study is to evaluate the efficacy and safety of hepatic arterial infusion chemotherapy (HAIC) of oxaliplatin plus fluorouracil/leucovorin compared with HAIC of oxaliplatin alone in patients with hepatocellular…
- Trial name
- NCT03468231
- Testing
- Sorafenib, HAIC of FOLFOX, HAIC of OXA
- Where
- 7 sites in China
- Volunteers
- 300 people
- Sponsor
- Sun Yat-sen University
Venous Thrombosis, Critical Illness
Risk Prediction of Venous Thromboembolism in Critically Ill
Introduction: Venous thromboembolism (VTE), including both deep vein thrombosis and pulmonary embolism, is a frequent cause of morbidity and mortality.
- Trial name
- NCT03773939
- Where
- Netherlands
- Volunteers
- 5,400 people
- Sponsor
- University Medical Center Groningen
IBD, Venous Thromboembolism
Postoperative Extended Venous Thromboprophylaxis in Inflammatory Bowel Disease
Inflammatory bowel disease (IBD) is a relatively common disease that effects all age groups and carries significant morbidity and mortality.
- Conditions
- IBD, Venous Thromboembolism, Crohn Disease, Ulcerative Colitis
- Trial name
- EXPAND (NCT03935451)
- Testing
- Apixaban 2.5 milligram
- Where
- 2 sites in Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- McMaster University
Venous Thromboembolism
Study of DU-176b, Prevention of Venous Thromboembolism in Patients After Hip Fracture Surgery
The objective of this study is to evaluate the safety and efficacy of DU-176b compared with enoxaparin sodium for the prevention of venous thromboembolism in patients after elective hip fracture surgery.
- Trial name
- NCT01181141
- Testing
- DU-176b (edoxaban), Enoxaparin sodium 20mg
- Where
- Japan
- Volunteers
- 92 people
- Sponsor
- Daiichi Sankyo Co., Ltd.
Venous Thromboembolic Disease, Post Thrombotic Syndrome
Long-term Outcome After Edoxaban Versus Vitamin K Antagonists for Acute VTE
The HOKUSAI post VTE study contains of two different research questions; one on the long term outcomes of deep vein thrombosis and one on the long term effects of pulmonary embolism, post thrombotic syndrome (PTS) and chronic…
- Conditions
- Venous Thromboembolic Disease, Post Thrombotic Syndrome, Chronic Thromboembolic Pulmonary Hypertension, Quality of Life
- Trial name
- HOKUSAIpostVTE (NCT04007653)
- Testing
- Observation
- Where
- Netherlands
- Volunteers
- 1,200 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Complications
Standard Length Catheters vs Long Catheters in Peripheral Vein Cannulation.
The Long and Short is a prospective, randomized, controlled, open label trial to test the complications of different device for peripheral vein cannulation, standard length (about 5 cm in length) and long catheter (about 12 cm in…
- Trial name
- Long&short (NCT01917253)
- Testing
- Standard Device for peripheral vein cannulation, Long Catheters for peripheral vein cannulation
- Where
- Italy
- Volunteers
- 220 people
- Sponsor
- ASL TO2 Torino
Thromboembolism, Unspecified Adult Solid Tumor, Protocol Specific
Standard Diagnostic Procedures With or Without Fludeoxyglucose F 18 Positron Emission Tomography in Finding Cancer in Patients With a Blood Clot in a Vein
RATIONALE: Diagnostic procedures, such as fludeoxyglucose F 18 positron emission tomography, may help find and diagnose cancer. It is not yet known whether standard diagnostic procedures are more effective when given with or…
- Trial name
- MVTEP (NCT00964275)
- Testing
- diagnostic procedure, fludeoxyglucose F 18
- Where
- France
- Volunteers
- 400 people
- Sponsor
- University Hospital, Brest
Venous Thrombosis Deep (Limbs), Surgical Blood Loss
Pre-operative Enoxaparin in the Surgical Management of Multi-trauma Patients Undergoing Orthopedic Surgical Procedures
All trauma patients receive Lovenox or other prophylactic medication to prevent deep vein clots from forming. For the trauma patients with orthopedic injuries requiring surgery there is controversy over safety and efficacy when…
- Trial name
- NCT05081375
- Testing
- Enoxaparin Injectable Product, Sodium chloride
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Valleywise Health
Hepatocellular Carcinoma Non-resectable, Portal Vein Tumor Thrombosis
Stereotactic Body Radiotherapy Based Treatment for Hepatocellular Carcinoma With Extensive Portal Vein Tumor Thrombosis
Macrovascular invasion (MVI) is common in HCC, Portal vein tumor thrombus (PVTT) is the most common form of MVI in HCC, with an incidence ranging from 44 to 62.2%.
- Conditions
- Hepatocellular Carcinoma Non-resectable, Portal Vein Tumor Thrombosis, Stereotactic Body Radiotherapy
- Trial name
- NCT04966195
- Testing
- stereotactic body raiotherapy
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
COVID-19, Venous Thromboembolism
Prevalence and Severity of Venous Thromboembolism in a General Population During the COVID-19 Pandemic
The purpose of this study is to investigate the prevalence of venous thromboembolism in a regional health care system (Region Östergötland, Sweden) before and during the SARS-COV-2 pandemic.
- Conditions
- COVID-19, Venous Thromboembolism, Pulmonary Embolism, Deep Vein Thrombosis
- Trial name
- NCT04400877
- Testing
- Diagnostic examination for venous thromboembolism
- Where
- Sweden
- Volunteers
- 7,795 people
- Sponsor
- University Hospital, Linkoeping
Venous Thromboembolism, Critical Illness
Predicting the Risk of Venous Thromboembolism in Critically Ill Patients
Introduction: Venous thrombosis (VTE), including both deep vein thrombosis (DVT) and pulmonary embolism (PE) remains a frequent complication in patients admitted to the Intensive Care Unit (ICU).
- Trial name
- NCT05498142
- Volunteers
- 7,600 people
- Sponsor
- University Medical Center Groningen
Cerebral Thrombosis, Venous Thrombosis
TOF-MRV Versus Post-Contrast 3D T1 MRI in Dural Venous Sinus Thrombosis
This cross-sectional study aims to compare the diagnostic performance of time-of-flight MR venography and post-contrast 3D T1-weighted MRI in the detection of dural venous sinus thrombosis.
- Trial name
- NCT07888062
- Volunteers
- 80 people
- Sponsor
- Assiut University
Hepatocellular Carcinoma
Radioembolization for Hepatocellular Carcinoma With Portal Vein Tumoral Thrombosis
In patients with hgepatocellular carcinoma (HCC) and portal vein tumoral thrombosis (PVTT), Sorafenib represents the treatment of choice but more recently, trans-arterial radioembolization (TARE) with yttrium-90 has been also…
- Trial name
- NCT04771988
- Testing
- yttrium-90 radioembolization
- Volunteers
- 17 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Deep Venous Thrombosis
Simplification of the Diagnosis of Deep Vein Thrombosis
Prospective cohort study aimed at simplifying the diagnostic approach to symptomatic patients with the clinical suspicion of deep vein thrombosis (DVT) of the lower extremities.
- Trial name
- PALLADIO (NCT01412242)
- Testing
- Extensive search for isolated calf DVT
- Where
- Italy
- Volunteers
- 1,100 people
- Sponsor
- University of Padova
Achilles Tendon Ruptures, Immobilization
Achilles Tendon Rupture - Intervention With Electrical Stimulation
Acute Achilles tendon rupture (ATR) is an injury that is commonly associated with complications, such as blood clotting, muscle loss and tendon lengthening, all of which affect the long-term outcome and return to sports.
- Conditions
- Achilles Tendon Ruptures, Immobilization, Venous Thromboembolism (VTE), Muscle Atrophy
- Trial name
- C-NMES-ATR (NCT06601088)
- Testing
- Neuromuscular Electrical Stimulation
- Volunteers
- 220 people
- Sponsor
- Karolinska University Hospital
Venous Thromboembolism, Venous Thromboses
inDividual, Targeted thrombosIS Prophylaxis Versus the Standard 'One Size Fits All' Approach in Patients Undergoing Total hIp or Total kNee replaCemenT
After hip or knee replacement all patients receive a standardized treatment with blood thinners, this medication is called thrombosis prophylaxis.
- Conditions
- Venous Thromboembolism, Venous Thromboses, Pulmonary Embolism, Deep Vein Thrombosis
- Trial name
- DISTINCT (NCT06581965)
- Testing
- Short duration prophylaxis, Higher intensity and longer duration prophylaxis, Control
- Where
- 13 sites in Netherlands
- Volunteers
- 10,078 people
- Sponsor
- Leiden University Medical Center
Portal Vein Thrombosis
Efficacy and Safety of Rivaroxaban in Acute Non-neoplastic Portal Vein Thrombosis in HCV
Portal vein thrombosis (PVT) in patients with liver cirrhosis may be due to neoplastic growth or non-neoplastic causes. Treating PVT with anticoagulation in liver cirrhosis is difficult to be established but may be of great…
- Trial name
- NCT03201367
- Testing
- Rivaroxaban, symptomatic therapy for ascites, abdominal pain
- Volunteers
- 40 people
- Sponsor
- Zagazig University
Retinal Vein Occlusion
Combined Intravitreal Injection of Bevacizumab and Fasudil Versus Bevacizumab Alone for Macular Edema Secondary to Retinal Vein Occlusion in Previously Treated Patients
This study is aimed to compare the effect of combined intravitreal Bevacizumab and Fasudil injection with Bevacizumab only injection in patients with persistant macular edema secondary to ratinal vein occlusion.
- Trial name
- NCT03391219
- Testing
- injection bevacizumab, injection Combined Bevacizumab and Fasudil
- Where
- Iran
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Shahid Beheshti University of Medical Sciences
Venous Thrombosis, Venous Insufficiency
Evaluating the Relationship Between Blood Clotting Disorders, Inflammation, and Obesity in Individuals With Venous Disorders and Post-Thrombotic Syndrome
Venous thrombosis is the development of a blood clot in a vein. Post-thrombotic syndrome (PTS) is a painful condition that can develop following a venous thrombosis in one of the deep veins of the leg.
- Trial name
- NCT00395265
- Where
- United States
- Volunteers
- 2,211 people, healthy volunteers welcome
- Sponsor
- University of Vermont
Deep Venous Thrombosis
D-Dimer Guided Oral Anticoagulant Treatment (OAT)
This clinical trial will investigate the hypothesis that D-Dimer testing can be successfully used to tailor the duration of OAT in patients after an unprovoked episode of deep venous thrombosis (DVT) using a prospective…
- Trial name
- DDOAT2006 (NCT00895505)
- Testing
- Phenprocoumon, Warfarin-Natrium
- Where
- Germany
- Volunteers
- 300 people
- Sponsor
- University Hospital, Bonn
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