Clinical trials: Venous Thrombosis (Disorder)
Varicose Veins of Lower Limb, Thromboses, Venous
Prospective Cohort Study for Varicose Veins Incidence and Natural Course
A prospective study of individuals without varicose veins and who have primary varicose veins to assess the morbidity, risk factors and natural course of chronic lower limb vein disease.
- Conditions
- Varicose Veins of Lower Limb, Thromboses, Venous, Venous Insufficiency
- Trial name
- VINCI (NCT04546750)
- Where
- Russia
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Russian Phlebological Association
Glioblastoma, Astrocytoma
Venous Thromboembolism Prevention in Outpatients With Glioma
This is an open label study of apixaban for venous thromboembolism prevention in patients with newly diagnosed grade 4 glioma.
- Conditions
- Glioblastoma, Astrocytoma, Venous Thromboembolism
- Trial name
- VTE-POG (NCT05683808)
- Testing
- Apixaban
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Vermont Medical Center
Thromboembolism, Anticoagulant-induced Bleeding
Optimization of Management in Patients With Cardiovascular Disease After Lower Limb Joint Replacement
The goal of the study is to evaluate the frequency of cardiovascular and thromboembolic complications in patients with cardiovascular disease after lower limb joint replacement, the influence of known risk factors and strategies…
- Trial name
- NCT06627933
- Testing
- No intervention
- Where
- Russia
- Volunteers
- 1,733 people
- Sponsor
- I.M. Sechenov First Moscow State Medical University
Thrombosis, Prevention
Re-STOP DVT: Reload of High Dose Atorvastatin for Preventing Deep Vein Thrombosis in Statin Users
Reload of high dose statin may have potential for preventing deep vein thrombosis (DVT) in patients on statin undergoing total knee replacement arthroplasty.
- Conditions
- Thrombosis, Prevention, Surgery
- Trial name
- Re-STOP DVT (NCT01063426)
- Testing
- High dose Atorvastatin+enoxaparin, Enoxaparin
- Where
- South Korea
- Volunteers
- 180 people
- Sponsor
- Hallym University Medical Center
Cancer-associated Thrombosis, Venous Thromboembolism
The Gynecological Cancer Associated Thrombosis (GynCAT) Study
GynCAT is a prospective cohort study that will be conducted on female patients with gynecologic malignancies scheduled for systemic antineoplastic treatment, aiming at development and validation of a Risk Assessment Model (RAM)…
- Conditions
- Cancer-associated Thrombosis, Venous Thromboembolism, Gynecologic Cancer, Ovarian Cancer
- Trial name
- GynCAT (NCT06284343)
- Testing
- Anticoagulant
- Where
- Italy
- Volunteers
- 1,800 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Deep Vein Thrombosis, Pulmonary Embolism
Extended-Duration Low-Intensity Apixaban to Prevent Recurrence in High-Risk Patients With Provoked Venous Thromboembolism
Design: U.S.-based, single-center, randomized placebo-controlled trial. Brief Treatment Description: Low-intensity apixaban (2.5mg twice daily) for extended-duration secondary prevention of VTE after initial treatment for…
- Conditions
- Deep Vein Thrombosis, Pulmonary Embolism, Venous Thromboembolism
- Trial name
- HI-PRO (NCT04168203)
- Testing
- Apixaban 2.5 MG
- Where
- United States
- Volunteers
- 600 people
- Sponsor
- Brigham and Women's Hospital
Deep Vein Thrombosis
SCD Use to Prevent Deep Venous Thrombosis (DVT) in Patients With PICC Lines
The purpose of this study is to see if a compression device on the arm where a peripherally inserted central catheter (PICC) line has been inserted can prevent the formation of a blood clot around the PICC line.
- Trial name
- NCT01670188
- Testing
- Pneumatic SCD - VenaFlow System (DJO Global)
- Where
- United States
- Volunteers
- 78 people
- Sponsor
- Mayo Clinic
Cardiovascular Diseases, Venous Thromboembolism
LEAVE Safe With DOACs
Given the risks associated with direct oral anticoagulants (DOACs) and the lack of defined pathways for patients prescribed this class of medications, the study intervention has the potential for an enormous impact in preventing…
- Conditions
- Cardiovascular Diseases, Venous Thromboembolism, Atrial Fibrillation, Bleeding
- Trial name
- NCT04068727
- Testing
- Clinical Pharmacist Intervention
- Where
- United States
- Volunteers
- 561 people
- Sponsor
- University of Massachusetts, Worcester
Breast Reconstruction, Thrombosis, Venous
Bioimpedance Measurement of Abdominal Free Flaps During Arterial and Venous Weaning in Breast Reconstruction
As the occurrence of thrombosis in post surgery is rare, it seemed difficult to study only this one. This is why we decided to test the bioimpedance, temperature and green, red and infrared light absorption measurements of the…
- Conditions
- Breast Reconstruction, Thrombosis, Venous, Bioimpedance Measurement Capacity
- Trial name
- MONITRANS2 (NCT05710705)
- Testing
- portable prototype of bioimpedance measurement
- Where
- France
- Volunteers
- 10 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Post Thrombotic Syndrome, Deep Vein Thrombosis
Long-term Outcome After Heparin and Edoxaban Versus Heparin Plus Vit K Antagonists for Acute DVT and PE
Centers that participated in the HOKUSAI VTE trial will be invited to collect follow of previously enrolled patients at least 2 years after the index VTE.
- Conditions
- Post Thrombotic Syndrome, Deep Vein Thrombosis, Chronic Thromboembolic Pulmonary Hypertension
- Trial name
- NCT03757481
- Testing
- no intervention
- Where
- 11 sites in France
- Volunteers
- 156 people
- Sponsor
- University Hospital, Montpellier
Cerebral Venous Thrombosis, Anticoagulants and Thrombotic Disorders
Safety and Efficacy of Edoxaban and Rivaroxaban to Cerebral Venous Thrombosis in Chinese Patients
The goal of this observational study is to learn the safety and efficacy of edoxaban and rivaroxaban in Chinese population with the age range from 18 to 80 years who take edoxaban or rivaroxaban to treat their cerebral venous…
- Conditions
- Cerebral Venous Thrombosis, Anticoagulants and Thrombotic Disorders, Anticoagulation Treatment, Anticoagulant Therapy
- Trial name
- NCT06947707
- Where
- China
- Volunteers
- 1,486 people
- Sponsor
- Xuanwu Hospital, Beijing
Venous Thromboembolism, Hypercholesterolemia
Statins to Reduce D-dimer Levels in Patients With Venous Thrombosis
Elevated levels of D-dimer, a marker of procoagulant state, have been identified as a marker of an increased risk of recurrent VTE.
- Trial name
- NCT00437892
- Testing
- atorvastatin, diet
- Where
- 3 sites in Italy
- Volunteers
- 10 people
- Sponsor
- Università degli Studi dell'Insubria
Hepatocellular Carcinoma, Portal Vein Tumor Thrombosis
Irradiation Stent Placement Plus TACE for HCC and PVTT
The study is a multicenter, randomized (1:1), open-label, parallel-arm, Phase 3 clinical trial to evaluate the efficacy and safety of portal irradiation stent placement plus TACE compared to sorafenib plus TACE in patients with…
- Trial name
- NCT03730675
- Testing
- Portal irradiation stent placement, TACE, Sorafenib
- Where
- China
- Volunteers
- 308 people
- Sponsor
- Zhongda Hospital
Varicose Veins, Superficial Venous Thrombosis
Comparison of Daytime Surgery in Varicose Veins Patients With and Without Superficial Venous Thrombosis
Varicose veins of lower extremities are the most common disease in vascular surgery, and daytime surgery has gradually become the mainstream of varicose veins of lower extremities.
- Conditions
- Varicose Veins, Superficial Venous Thrombosis, Day Surgery
- Trial name
- NCT05380895
- Where
- China
- Volunteers
- 699 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Deep Vein Thrombosis
D-dimer and Pre-test Clinical Probability Score in Cancer Patients With Suspected Deep Vein Thrombosis of the Legs
Patients with cancer have a high risk of deep vein thrombosis which often develops in the veins of the lower limbs. The initial evaluation of clinically suspected deep vein thrombosis includes the estimation of the clinical…
- Trial name
- NCT02341937
- Testing
- Diagnostic tests for suspected deep vein thrombosis
- Where
- Italy
- Volunteers
- 239 people
- Sponsor
- G. d'Annunzio University
Venous Thromboembolism (VTE)
Identification of New Genetic Markers for the Risk of Recurrence of Venous Thromboembolism by Whole Genome Analysis
Venous thromboembolism (VTE) is a common and potentially fatal pathology in France. The risk of recurrence is around 5 to 7% per year.
- Trial name
- MARTHARecidive (NCT03977870)
- Testing
- vital status determination
- Where
- France
- Volunteers
- 843 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Venous Thrombosis
Tourniquet Study: A Clinical Trial Into the Effect of Tourniquet Use on the Coagulation System
Knee arthroscopy is the most commonly performed orthopaedic procedure worldwide, with, according to the American Society for Sports Medicine, over 4 million procedures performed each year.
- Trial name
- NCT02567903
- Testing
- Thigh Tourniquet, Knee arthroscopy
- Where
- Netherlands
- Volunteers
- 55 people
- Sponsor
- Groene Hart Ziekenhuis
Venous Thromboembolism
Dose-ranging Study of Once-daily Regimen of BAY 59-7939 in the Prevention of VTE in Patients Undergoing Elective Total Hip Replacement
The purpose of this study is to assess different doses of a new drug (BAY 59-7939), taken as a tablet, are safe and can help prevent blood clots forming after a hip replacement operation.
- Trial name
- ODIXaHIP-OD (NCT00396786)
- Testing
- Rivaroxaban (Xarelto, BAY59-7939), Enoxaparin
- Where
- 62 sites in Austria, Belgium and 11 more
- Volunteers
- 877 people
- Sponsor
- Bayer
Venous Thromboembolism, Pulmonary Embolism
Exclusion of Venous Thrombo-Embolism With a New Clinical Decision Support
The goal of this non interventional study is to demonstrate the diagnostic performances on fresh plasmas in comparison with the performances on frozen plasmas in any patients with VTE suspicion, whatever the pre-test probability.
- Conditions
- Venous Thromboembolism, Pulmonary Embolism, Deep Vein Thrombosis
- Trial name
- EXTEND (NCT06480994)
- Testing
- Routine Assays on fresh plasma, New Clinical Decision Support on fresh plasma, New Clinical Decision Support on frozen plasma
- Where
- 4 sites in France
- Volunteers
- 1,836 people
- Sponsor
- Diagnostica Stago R&D
Prevention, Venous Thromboembolism
Regulation of Coagulation in Orthopedic Surgery to Prevent Deep Vein Thrombosis (DVT) and Pulmonary Embolism (PE). A Study of BAY 59-7939 in the Prevention of VTE in Subjects Undergoing Elective Total Knee Replacement.
The purpose of this study is to assess if 10 mg Bay 59-7939, taken once daily as a tablet, is safe and prevents blood clot which may form after a knee replacement operation.
- Trial name
- RECORD 3 (NCT00361894)
- Testing
- Rivaroxaban (BAY59-7939), Enoxaparin
- Where
- 143 sites in Austria, Belgium and 17 more
- Volunteers
- 2,531 people
- Sponsor
- Bayer
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