Clinical trials: Venous Thrombosis (Disorder)
Age Related Macular Degeneration, Diabetic Macular Edema
Collateral Damage From the COVID-19 Pandemic Observed in Patients Treated With Intravitreal Injections (IVT) of Anti-angiogenic Agents
In patients treated for exudative age-related macular degeneration (AMD), diabetes, retinal venous occlusion (OVR), or other conditions causing macular edema, treatments with anti-angiogenic intravitreal injections (IVT) are…
- Conditions
- Age Related Macular Degeneration, Diabetic Macular Edema, Retinal Vein Occlusion
- Trial name
- COVIDIV (NCT04395859)
- Testing
- Questionnaire, Data collection up to 1 year
- Where
- 4 sites in France
- Volunteers
- 233 people
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Venous Thromboembolism
Multiple-Dose Study Apixaban in Pediatric Subjects With an Indwelling Central Venous Catheter
CV185-079 is a multiple dose Apixaban Pharmacokinetics/Pharmacodynamics (PK/PD) study in pediatric subjects. The objective of this study is primarily to study the PK/PD of Apixaban in pediatric subjects with a central venous…
- Trial name
- NCT01195727
- Testing
- Apixaban
- Where
- 14 sites in United States, Belgium and 3 more
- Volunteers
- 13 people
- Sponsor
- Bristol-Myers Squibb
Retinal Vein Occlusion
Extended Follow-up of Patients With Macular Edema Due to Retinal Vein Occlusion
This study evaluates long-term safety in patients with macular edema due to Retinal Vein Occlusion (RVO) originally enrolled in the BRAVO \& CRUISE trials and subsequently followed in the HORIZON extension trial.
- Trial name
- RETAIN (NCT01198327)
- Testing
- ranibizumab, Peripheral Laser
- Where
- 6 sites in United States
- Volunteers
- 66 people
- Sponsor
- Peter A Campochiaro, MD
Pulmonary Embolism, Acute Pulmonary Embolism
CLEANer Aspiration for Pulmonary Embolism
To evaluate the safety and efficacy of the Cleaner™ Pro Thrombectomy System for aspiration thrombectomy in patients with acute pulmonary embolism (PE).
- Conditions
- Pulmonary Embolism, Acute Pulmonary Embolism, Cardiovascular Diseases, Venous Thromboembolism
- Trial name
- CLEAN-PE (NCT06189313)
- Testing
- Cleaner Pro Thrombectomy System
- Where
- 14 sites in United States
- Volunteers
- 125 people
- Sponsor
- Argon Medical Devices
HepatoCellular Carcinoma
Radiotherapy in Hepatocellular Carcinomas After Hepatectomy With Narrow Margin (<1 cm) or Portal Vein Thrombosis
Hepatocellular carcinoma (HCC) is one of ten leading cancer types worldwide and also in Asia, but the five-year relative survival rate is relatively quite low1-3.
- Trial name
- RHCC (NCT02309788)
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Guangxi Medical University
HepatoCellular Carcinoma, Portal Vein Thrombosis
Sorafenib Plus Hepatic Arterial Infusion Versus Sorafenib for HCC with Major Portal Vein Tumor Thrombosis
According to the Barcelona clinic liver cancer (BCLC) staging treatment guideline, sorafenib is recommended for Hepatocellular Carcinoma (HCC) with Portal Vein Tumor Thrombosis (PVTT), but HCC with major PVTT (in the main trunk…
- Trial name
- NCT03009461
- Testing
- HAIC, Sorafenib
- Where
- China
- Volunteers
- 64 people
- Sponsor
- Peking University
Macular Edema, Retinal Vein Occlusion
A Study of the Safety and Efficacy of a New Treatment for Macular Edema Resulting From Retinal Vein Occlusion
This study will evaluate the safety and efficacy of an intravitreal implant of dexamethasone for the treatment of macular edema associated with retinal vein occlusion.
- Trial name
- NCT00168298
- Testing
- 700 µg Dexamethasone, 350 µg Dexamethasone
- Where
- 13 sites in United States, Brazil and 11 more
- Volunteers
- 668 people
- Sponsor
- Allergan
Deep Venous Thrombosis
The SOX Trial: Compression Stockings to Prevent the Post-Thrombotic Syndrome
The purpose of this study is to determine whether elastic compression stockings used for 2 years are effective in preventing the post-thrombotic syndrome in patients with symptomatic proximal deep venous thrombosis.
- Trial name
- NCT00143598
- Testing
- Knee-length, graduated elastic compression stocking
- Where
- 25 sites in United States, Canada
- Volunteers
- 806 people
- Sponsor
- Sir Mortimer B. Davis - Jewish General Hospital
Venous Thromboembolism
Medication Use Evaluation for Enoxaparin in Hospitalized COVID-19 Patients
Retrospective chart review to be conducted at Methodist Richardson Medical Center (MRMC) in Richardson, TX. All adult patients hospitalized with COVID-19 on enoxaparin for DVT prophylaxis will be included.
- Trial name
- NCT05226793
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- Methodist Health System
Venous Thromboembolism, Deep Venous Thrombosis
Twice Daily Enoxaparin Prophylaxis in Reconstructive Surgery Patients
Blood clots that form in the extremities (deep venous thrombosis) and lungs (pulmonary embolus) are feared complications of reconstructive surgery.
- Conditions
- Venous Thromboembolism, Deep Venous Thrombosis, Pulmonary Embolus
- Trial name
- NCT02687204
- Testing
- Twice daily enoxaparin prophylaxis, Real time dose adjustment
- Where
- United States
- Volunteers
- 118 people
- Sponsor
- University of Utah
Cardiovascular Disease, Venous Thromboses
Education Program for Patients Receiving Oral Anticoagulation
The aim of the study is to test if patients under oral anticoagulation therapy who are going to participate in the education program will have better Health-related quality of life, higher rate in pharmacological treatment…
- Conditions
- Cardiovascular Disease, Venous Thromboses, Atrial Fibrillation, Blood Coagulation Disorders, Inherited
- Trial name
- NCT01339611
- Testing
- Educational program
- Where
- Brazil
- Volunteers
- 160 people
- Sponsor
- University of Sao Paulo
Venous Thromboembolism
Pharmacokinetics of Enoxaparin in Intensive Care Patients
To evaluate the pharmacokinetics of the thromboprophylactic agent enoxaparin in critically ill patients by comparing plasma anti-factor Xa activity when enoxaparin is administered either as a continuous intravenous infusion or…
- Trial name
- NCT02095509
- Testing
- Enoxaparin
- Where
- 2 sites in Finland
- Volunteers
- 39 people
- Sponsor
- Tampere University Hospital
Hepatocellular Carcinoma, Portal Vein Tumour Thrombosis
Neoadjuvant Combination of Atezolizumab/Bevacizumab Versus Neoadjuvant Radiation Therapy
A multicentre, parallel group, randomized controlled Phase II clinical trial evaluating neoadjuvant Atezolizumab/Bevacizumab versus neoadjuvant SBRT in patients with biopsy proven solitary HCC with PVTT involving the portal vein…
- Trial name
- ADVANCE HCC (NCT05137899)
- Testing
- Neoadjuvant
- Where
- 7 sites in Canada
- Volunteers
- 1 people
- Sponsor
- Ontario Clinical Oncology Group (OCOG)
Budd-Chiari Syndrome
To Compare "Balloon Occluded Thrombolysis" With "Conventional Catheter Directed Thrombolysis" in Thrombotically Occluded DIPSS Stent in Patients of Budd- Chiari Syndrome.
DIPSS has become a widely accepted treatment for complications of portal hypertension. Shunt or hepatic vein stenosis are common short and mid term complications of the procedure.
- Trial name
- NCT05117684
- Testing
- Novel, Conventional
- Where
- India
- Volunteers
- 33 people
- Sponsor
- Institute of Liver and Biliary Sciences, India
Venous Thromboembolism, Hemorrhage
A Clinical Cohort Study of Safety and Effectiveness of Venous Thromboembolism Prophylaxis in Critical Ill Patients
The purpose of this study is to analyze the effect of the prophylaxis of venous thromboembolism in the critical ill patients, and at the same time, to find out the risk of venous thromboembolism and hemorrhage events occurred…
- Trial name
- VTEH (NCT02213978)
- Where
- China
- Volunteers
- 1,114 people
- Sponsor
- Beijing Chao Yang Hospital
Ankle Motion, Gynecologic Neoplasm
Functional Training for the Prevention of Deep Venous Thrombosis
This study aims to analyze the post-operative functional training on the prevention of deep venous thrombosis (DVT) in the patients who have accepted major surgeries for the gynecological malignancies.
- Conditions
- Ankle Motion, Gynecologic Neoplasm, Deep Venous Thrombosis, Abdominal Breathing
- Trial name
- NCT03740633
- Testing
- passive ankle pump motions on the day of surgery, active ankle pump motions and abdominal breathing training on the 1-3 day after the surgery, Regular care
- Where
- China
- Volunteers
- 398 people
- Sponsor
- Lei Li
Age-Related Macular Degeneration, Geographic Atrophy
Evaluation of the Precision of the Microperimetry Function of the Spectral OCT/SLO
To conduct a precision study to assess the microperimetry function of the Spectral OCT/SLO. The study will assess variability across measurements taken by three different operator-device configuration across clinical sites…
- Conditions
- Age-Related Macular Degeneration, Geographic Atrophy, Diabetic Retinopathy, Macular Edema
- Trial name
- NCT01692938
- Where
- 3 sites in United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Optos, PLC
Thrombosis Prophylaxis (Risk of Thrombosis Due to Central Venous Line (CVL)
Study of AVE5026 at Weight-adjusted Doses in Children With a Central Venous Line
Primary Objective: To assess the pharmacokinetic (PK) and pharmacodynamic (PD) parameters of Semuloparin [AVE5026] (assessed from the anti-Xa activity of Semuloparin) in children in order to determine the dose to be assessed in a…
- Trial name
- NCT01567904
- Testing
- Semuloparin sodium
- Where
- Hungary
- Volunteers
- 2 people
- Sponsor
- Sanofi
Post-COVID-19 Condition, Ulcerative Colitis
Emerging Indications for Hyperbaric Oxygen Treatment
This study will evaluate the effectiveness of hyperbaric oxygen therapy (HBOT) on treating emerging indications (i.e., conditions that have shown to potentially benefit from HBOT) using the Multicenter Registry for Hyperbaric…
- Conditions
- Post-COVID-19 Condition, Ulcerative Colitis, Crohn Disease, Calciphylaxis
- Trial name
- NCT07240649
- Testing
- Hyperbaric oxygen treatment (HBOT), 100% Oxygen
- Volunteers
- 100 people
- Sponsor
- Jay C. Buckey Jr.
Venous Thromboembolism
The Use of Fondaparinux in Preventing Thromboembolism in High Risk Trauma Patients
Trauma patients are at high risk of developing deep vein thrombosis (DVT) and pulmonary embolism (PE). The incidence of DVT varies greatly from 5-63% among studies depending on patient's individual risk factors, modality of…
- Trial name
- NCT00531843
- Testing
- fondaparinux sodium, sequential compression devices
- Where
- United States
- Volunteers
- 105 people
- Sponsor
- Mary Knudson, M.D.
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