Clinical trials: Venous Thrombosis Deep (Limbs)
Venous Thrombosis
Staging and Prognosis of Deep Venous Thrombosis of Lower Extremities
Deep venous thrombosis (DVT) is a venous reflux disorder caused by abnormal coagulation of blood in the deep vein, which usually occurs in the lower extremities.
- Trial name
- NCT04732299
- Testing
- MRI examination
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Venous Stasis, Deep Venous Thrombosis
Effects of External Leg Compression Devices on Healing and Blood Clotting
This study aims to compare two different external calf compression devices applied in healthy individuals. These devices are commonly used in medical care in order to prevent the formation of blood clots, for example during…
- Conditions
- Venous Stasis, Deep Venous Thrombosis, Healing Wound
- Trial name
- NCT03050671
- Testing
- Intermittent Pneumatic Compression, Rapid, Intermittent Pneumatic Compression, Slow
- Where
- Sweden
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Karolinska University Hospital
Catheter Thrombosis, Catheter-Related Infections
The Central Venous Catheter Related Complications in Critically Ill Patients
In this prospective clinical study, the researchers investigate the incidence of catheter-related thrombosis and catheter-related infection during indwelling central venous catheterization in critically ill patients, and analyzed…
- Conditions
- Catheter Thrombosis, Catheter-Related Infections, Central Venous Catheter Related Bloodstream Infection, Central Venous Catheter Thrombosis
- Trial name
- NCT03841240
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Zhujiang Hospital
Deep Venous Thrombosis
Comparison Between Xarelto Versus Warfarin in the Recanalization Rate of Deep Venous Thrombosis in Patients Legs.
This is a prospective, randomized study, aiming to evaluate patients with Deep Venous Thrombosis in lower limbs and the recanalization rates evaluated with DUPLEX ultrasound, as so the clinical outcomes in patients submitted to…
- Trial name
- DVT (NCT02704598)
- Testing
- Rivaroxaban, Warfarin
- Where
- Brazil
- Volunteers
- 84 people
- Sponsor
- Hospital do Servidor Publico Estadual
Central Venous Catheter Thrombosis, Central Venous Catheter Associated Bloodstream Infection
t-PA Prophylaxis to Prevent Catheter-associated Thrombosis and Infection
The purpose of this pilot study is to test feasibility of concept, consent and enrollment rates, and mechanics of study designed to assess if intra-catheter dwells of tissue plasminogen activator (t-PA) is effective in decreasing…
- Trial name
- TOPCAT (NCT03672006)
- Testing
- alteplase (recombinant t-PA), Heparin
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Medical College of Wisconsin
Deep Vein Thrombosis
Single Complete Compression Ultrasonography to Rule Out Deep Vein Thrombosis During Pregnancy and Postpartum
The objective of the EDVIGE study is to determine whether a negative single distal and proximal leg veins compression ultrasonography safely rules out the diagnosis of deep vein thrombosis in pregnant and post-partum women with…
- Trial name
- EDVIGE (NCT00740454)
- Testing
- Lower limb veins compression ultrasonography
- Where
- 2 sites in France, Switzerland
- Volunteers
- 200 people
- Sponsor
- University Hospital, Brest
Catheter Related Complication
Central Venous Catheter-Related Thrombosis in Critically Ill Patients
This project aims to identify catheter-related thrombosis (CRT) and determine its incidence, associated factors, and outcomes. The eligible patients will undergo daily ultrasound just distal to the central venous catheter…
- Trial name
- CVC-RT (NCT06573112)
- Testing
- ultrasound assessment for catheter-related thrombosis.
- Where
- Oman
- Volunteers
- 315 people
- Sponsor
- Sultan Qaboos University
Deep Vein Thrombosis, Covid19
Evaluation of Serial Ultrasound Screening in ICU COVID-19 Patients
This clinical trial is designed to evaluate if the periodic screening for deep venous thrombosis by ultrasound of lower extremity in patients with intensive care unit (ICU) patients with COVID 19 impacts on mortality, ICU stay…
- Conditions
- Deep Vein Thrombosis, Covid19, COVID-19 Pneumonia, COVID-19 Respiratory Infection
- Trial name
- NCT05028244
- Testing
- venous ultrasound of lower extremity
- Where
- Spain
- Volunteers
- 168 people
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Venous Thromboembolism
Colchicine to Quench the Inflammatory Response After Deep Vein Thrombosis (The Conquer-DVT Pilot Trial)
This trial seeks to assess the feasibility of a full-scale, double-blind, placebo-controlled, randomized trial assessing whether low-dose colchicine (0.5 mg daily) reduces the risk of post-thrombotic syndrome (PTS) in patients…
- Trial name
- NCT06440694
- Testing
- Colchicine 0.5 mg po
- Where
- 4 sites in Canada
- Volunteers
- 150 people
- Sponsor
- Ottawa Hospital Research Institute
Thrombosis, Venous
A Study to Evaluate the Efficacy and Safety of Fondaparinux for the Prevention of Venous Blood Clots in Patients With a Plaster Cast or Other Type of Immobilization for a Below-knee Injury Not Needing Surgery
The purpose of this study is to evaluate the efficacy and safety of fondaparinux in comparison with a heparin (nadroparin) in preventing deep vein thrombosis (blood clots in the leg veins), whether symptomatic or detected by…
- Trial name
- FONDACAST (NCT00843492)
- Testing
- Fondaparinux sodium, Nadroparin
- Where
- 122 sites in France, Germany and 4 more
- Volunteers
- 1,351 people
- Sponsor
- GlaxoSmithKline
Venous Thromboembolism, Deep Vein Thrombosis
RIVAroxaban Versus Low-molecular Weight Heparin in Patients With Lower Limb Trauma Requiring Brace or CASTing
Lower limb trauma requiring immobilization is a very frequent condition that is associated with an increased risk of developing venous thromboembolism (VTE).
- Conditions
- Venous Thromboembolism, Deep Vein Thrombosis, Pulmonary Embolism, Lower Limb Trauma
- Trial name
- RIVACAST (NCT06195540)
- Testing
- Rivaroxaban 10 MG, Low Heparin Molecular Weight
- Where
- 37 sites in France
- Volunteers
- 1,424 people
- Sponsor
- University Hospital, Angers
Deep Vein Thrombosis
Diagnostic Performance of General Practitioners in Compression UltraSound
The objective of this study is to evaluate the diagnostic efficiency of general practitioners for the diagnosis of proximal deep vein thrombosis of the lower limbs compared with whole-leg ultrasound with Doppler performed by the…
- Trial name
- GPCUS (NCT05550038)
- Testing
- Compression ultrasound
- Where
- 19 sites in France
- Volunteers
- 15 people
- Sponsor
- University Hospital, Caen
Renal Failure Chronic Requiring Hemodialysis, Central Venous Catheterization
Duration and Adverse Events of Non-cuffed Catheter in Patients With Hemodialysis
The duration and adverse events of non-cuffed catheter in patients with hemodialysis will be investigated by multicenter prospective cohort.
- Conditions
- Renal Failure Chronic Requiring Hemodialysis, Central Venous Catheterization, Inadequate Hemodialysis Blood Flow, Venous Stenosis
- Trial name
- DACAPO (NCT02264964)
- Testing
- GamCath®, Arteriovenous fistula creation
- Volunteers
- 1,400 people
- Sponsor
- Shanghai Changzheng Hospital
Thrombosis, Venous
Evaluation Of Fondaparinux (Also Called ARIXTRA) 2.5 mg Subcutaneously Once Daily For The Treatment Of Superficial Thrombophlebitis (Also Known As Superficial Vein Thrombosis)
To evaluate fondaparinux 2.5mg subcutaneously once daily for 45 days in the treatment of acute (recent) superficial thrombophlebitis.
- Trial name
- NCT00443053
- Where
- 227 sites in Bulgaria, Czechia and 15 more
- Volunteers
- 3,002 people
- Sponsor
- GlaxoSmithKline
Deep Venous Thromboses
DVT Evaluation Using POCUS for Diagnosis and Treatment
This study will include approximately 50 patients who will be enrolled if there is suspicion of lower extremity deep vein thrombosis (DVT).
- Trial name
- NCT07400510
- Testing
- STAT Venous Duplex, Routine Venous Duplex
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Milton S. Hershey Medical Center
Venous Thrombosis Deep (Limbs), Surgical Blood Loss
Pre-operative Enoxaparin in the Surgical Management of Multi-trauma Patients Undergoing Orthopedic Surgical Procedures
All trauma patients receive Lovenox or other prophylactic medication to prevent deep vein clots from forming. For the trauma patients with orthopedic injuries requiring surgery there is controversy over safety and efficacy when…
- Trial name
- NCT05081375
- Testing
- Enoxaparin Injectable Product, Sodium chloride
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Valleywise Health
Nephrostomy; Complications, Fistula
HoloStream Study - Video Capture Device Usage
Objectives: Primary Evaluate the primary operator usability of VSI streaming software for realtime streaming of images from video capture devices to a head mounted display (Hololens 2) during Interventional Radiology procedures…
- Conditions
- Nephrostomy; Complications, Fistula, Central Venous Catheter Thrombosis
- Trial name
- Holo-Stream (NCT04774588)
- Testing
- VSI streamer and Microsoft Hololens 2 classed as a Class III device by Health Canada.
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Pulmonary Embolism
Prophylaxis Against DVTs After Primary Hip and Knee Replacement Surgery
The purpose of this research is to find a better way to prevent the post operative development of clots in the deep veins of the legs (also called Deep Vein Thrombosis or DVT).
- Trial name
- DVT (NCT00767559)
- Testing
- warfarin, Fondaparinux:
- Where
- United States
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- The New England Baptist Hospital
Upper Extremity Deep Vein Thrombosis, Secondary
The Side of Implantable Central Vascular Catheters and Complications
Whether the side of implantable CVCs was associated with the complication rates remains unclear. The investigators plan this study to explore this issue by randomizing patients to receive CVC implantation at the left subclavian…
- Trial name
- NCT01525277
- Where
- Taiwan
- Volunteers
- 246 people
- Sponsor
- National Taiwan University Hospital
Pharmacomechanical Thrombolysis, Deep Vein Thrombosis
The Study of Percutaneous Mechanical Thrombectomy Treating Acute Deep Vein Thrombosis of Lower Extremities
This study is a prospective, multicenter, real world, observational study intended to understand tmechanical thrombectomy in the treatment of acute deep venous thrombosis of lower extremities, It is estimated that 600 patients…
- Trial name
- NCT05356767
- Testing
- Pharmacomechanical thrombolysis
- Where
- China
- Volunteers
- 600 people
- Sponsor
- Chengdu University of Traditional Chinese Medicine