Clinical trials: Ventilated Patients
Septic Shock
Fever Control Using External Cooling in Mechanically Ventilated Patients With Septic Shock
The best strategy for managing fever in patients with septic shock remains unknown. In a pilot study, the investigators showed that fever control at normothermia allowed a better control of shock and evolution of organ failures.
- Trial name
- NCT04494074
- Testing
- External Cooling
- Where
- 33 sites in France
- Volunteers
- 820 people
- Sponsor
- Centre Hospitalier Intercommunal Creteil
Post Extubation Stridor, Upper Airway Ultrasonography
Role of Upper Airway Ultrasound in Predicting Weaning Outcomes in Mechanically Ventilated Patients
The goal of the study is to know the role of upper airway ultrasound in predicting weaning outcomes in mechanically ventilated patients , and the question is ,Is it the best to use or the conventional criteria of weaning
- Conditions
- Post Extubation Stridor, Upper Airway Ultrasonography, Upper Airway Edema
- Trial name
- NCT07580742
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Fayoum University
Mechanical Ventilation Complication, Weaning Failure
A Modified Cuff Leak Test and Reintubation in Mechanically Ventilated Patients
We hypothesized that the accuracy of the modified cuff leak test in predicting re-intubation in tracheal intubated patients is better than that of the conventional balloon leak test, thereby further reducing the re-intubation…
- Conditions
- Mechanical Ventilation Complication, Weaning Failure, Airway Obstruction
- Trial name
- NCT05550220
- Testing
- Cuff Leak Test
- Where
- China
- Volunteers
- 586 people
- Sponsor
- Beijing Chao Yang Hospital
Dietary Modification
COntinuous vs BOlus Nasogastric Feeding in Mechanically Ventilated Pediatric Patients 2
This multi-center, prospective, randomized comparative effectiveness intervention study will evaluate continuous feeding (CGF) and bolus gastric feeding (BGF) protocols and their effect on delivery of prescribed nutrition and…
- Trial name
- COBO2 (NCT02566070)
- Testing
- Continuous Gastric Feeding, Bolus Gastric Feeding
- Where
- 6 sites in United States
- Volunteers
- 147 people
- Sponsor
- Akron Children's Hospital
Ventilated Patient in Intensive Care, Failure of Extubation
The Rapid Shallow Breathing Index (RSBI) is a Widely Used Predictor for Weaning Patients From Mechanical Ventilation This Study Aims to Determine the Predictive Value of RSBI Measurements for Extubation Success in Mechanically Ventilated ICU Patients
Early extubation in ICU patients is crucial for reducing complications of prolonged ventilation, including morbidity and mortality.
- Trial name
- NCT07467265
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Ain Shams University
Long-term Sedation for Mechanical Ventilation, Critically Ill Intensive Care Unit Patients
Remimazolam vs Propofol for Long-Term Sedation in Mechanically Ventilated ICU Patients
This multicenter, randomized, controlled, non-inferiority trial is designed to determine whether remimazolam is non-inferior to propofol for prolonged sedation in adult ICU patients requiring mechanical ventilation for ≥48 hours.
- Trial name
- RePro-ICU (NCT07880548)
- Testing
- Remimazolam group, Propofol group
- Where
- 21 sites in China
- Volunteers
- 274 people
- Sponsor
- Sun Yat-sen University
Mechanically Ventilated ICU Patients
Evaluating the Patient-Ventilator Synchrony During Mechanical Ventilation in Patients With Acute Lung Injury
The overall purpose to the study is to prospectively study how often patients with and without acute lung injury (ALI) have patient-ventilator asynchrony demonstrated as stacked breaths.
- Trial name
- NCT01541514
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Chicago
ARDS
Artificial Intelligence in Categorizing the Severity of Oxygenation by Incorporating the PEEP Into the Definition of ARDS in Ventilated Patients
Artificial Intelligence in categorizing the severity of Oxygen in ventilated patients to predict initiation of treatment measures to improve mortality - P/FP ratio
- Trial name
- P/FP ratio (NCT05371314)
- Testing
- P/FP ratio
- Where
- Singapore
- Volunteers
- 5,000 people
- Sponsor
- National University Health System, Singapore
Respiration, Artificial
The Correlational Study of PPV in Various VT in Mechanically Ventilated Patients
Mesquida, J et al showed there was a significant linear correlation between pulse pressure variations under tidal volume 6 ml/kg and 8 ml/kg in patients after the resuscitation phase of severe sepsis and septic shock.
- Trial name
- NCT01950949
- Testing
- 300 ml Hydroxyethyl Starch 130/0.4 and Sodium Chloride Injection infusing in 15 minutes if PPV under VT 8 ml/kg was larger than 13% in the initial investigation
- Volunteers
- 69 people
- Sponsor
- Yi Liu
ARDS (Moderate or Severe), AHRF
STimulation to Activate RespIration
Multi-center, randomized, controlled, open-label Phase 2 feasibility trial. Subjects on mechanical ventilation (MV) for acute hypoxemic respiratory failure (AHRF) with lung injury (including subjects who meet criteria for acute…
- Conditions
- ARDS (Moderate or Severe), AHRF, Mechanically Ventilated ICU Patients
- Trial name
- STARI (NCT06832306)
- Testing
- Phrenic Nerve Stimulation
- Where
- 7 sites in United States, Canada
- Volunteers
- 30 people
- Sponsor
- Lungpacer Medical Inc.
Nursing Caries, Practice Nurse's Scope
Effect of Evidence-based Nursing Practices Training Program on the Competency of Nurses Caring for Mechanically Ventilated Patients
the overall aim of this study is to examine the effect of adapted Evidence-based nursing practices training program on the competency level of nurses caring for Mechanically ventilated patients in selected ICU in Egypt.
- Conditions
- Nursing Caries, Practice Nurse's Scope, Competence
- Trial name
- NCT05721664
- Testing
- Trianing program for nurse in how to provide evidence based practices for mechanically Ventilated Patients
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Cairo University
Mechanical Ventilation Complication, Ventilator Associated Pneumonia
Semirecumbent Position by Mechanical Ventilation
It's based in an observational trial in mechanical ventilated patients. The investigators assess the head of bed elevation angle in the routine treatment of the unit.
- Conditions
- Mechanical Ventilation Complication, Ventilator Associated Pneumonia, Compliance, Treatment
- Trial name
- NCT04149665
- Testing
- simple blind observation
- Where
- Switzerland
- Volunteers
- 30 people
- Sponsor
- Bürgerspital Solothurn
Severe Acute Respiratory Syndrome Coronavirus 2, Electric Impedance
Prone Positioning and Regional Ventilation in Mechanically Ventilated COVID-19 Patients
The consensus therapeutic strategy implies that COVID patients with acute lung injury due to coronavirus are routinely placed in prone position in an attempt to improve oxygenation by increasing ventilation homogeneity.
- Conditions
- Severe Acute Respiratory Syndrome Coronavirus 2, Electric Impedance, Prone Positioning
- Trial name
- COVID-19_EIT (NCT04359407)
- Testing
- Prone positioning
- Where
- Switzerland
- Volunteers
- 29 people
- Sponsor
- Walid HABRE
Effect of Protocolized Sedation on Days of Mechanical Ventilation in the ICU
Evaluation of an Analgosedation Protocol in Mechanically Ventilated Patients
The purpose of this study is to evaluate how the investigators provide sedation (medicine that make you sleepy) in the investigators intensive care unit (ICU).
- Trial name
- NCT02100735
- Testing
- Sedation protocol
- Where
- United States
- Sponsor
- Tampa General Hospital
COVID-19, Respiratory Failure
Compartmental Inflammation in Mechanically Ventilated Patients With COVID-19
The aim of the present study is to examine the inflammatory response in the pulmonary compartment and blood of critically ill patients admitted to the ICU with COVID-19.
- Trial name
- COV2ICU-DK (NCT04354584)
- Where
- Denmark
- Volunteers
- 20 people
- Sponsor
- Hvidovre University Hospital
Mechanical Ventilation Complication
Lowering PEEP: Weaning From High PEEP Setting
The perfusion of the deeply different areas coexisting in ARDS lung generates two type of venus-admixure : true shunt and shunt effect.
- Trial name
- NCT04429399
- Testing
- decrease the positive end expiratory pressure (PEEP), mechanical features assessment, shunt assessment
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- University of Bari
Covid19
Chest Radiography in COVID-19 Patients
To assess the prognostic performance of the RALE score with respect to duration of ventilation, and to describe changes in the RALE score over time.
- Trial name
- NCT04485338
- Where
- Netherlands
- Volunteers
- 139 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)