Clinical trials: Ventilator Dependent
Chronic Respiratory Failure, Tracheostomy Complication
Parental Perception of COVID-19 Vaccine in Technology Dependent Patients
This study involves conducting a telephonic or in person survey regarding parental perception and attitudes about vaccinating the respective "technology dependent" child with the COVID 19 vaccination.
- Conditions
- Chronic Respiratory Failure, Tracheostomy Complication, Mechanical Ventilation Complication
- Trial name
- NCT05084976
- Testing
- COVID 19 vaccine counseling
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Northwell Health
X-Linked Myotubular Myopathy
Study of ASP2957 in Male Participants With X-linked Myotubular Myopathy Who Need Ventilators
X-linked myotubular myopathy (XLMTM) is a rare and serious condition present at birth where the muscles do not work properly. There are currently no approved therapies for XLMTM.
- Trial name
- NCT07052929
- Testing
- ASP2957, Methylprednisolone, Prednisolone
- Where
- 5 sites in United States, Canada
- Volunteers
- 9 people
- Sponsor
- Astellas Gene Therapies
Respiration, Artificial, Critical Illness
Development of a Rehabilitation Strengthening and Mobility Program for Ventilator Dependent Older Patients
As the general population ages and technology advances, many who suffer from catastrophic critical illness (i.e. septic shock, respiratory failure, Acute Respiratory Disease Syndrome) survive only to find themselves severely…
- Conditions
- Respiration, Artificial, Critical Illness, Chronic Disease, Exercise Therapy
- Trial name
- NCT03195127
- Testing
- multimodal physical therapy
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- University of Maryland, Baltimore
Critical Care, Mechanical Ventilation
Does Threshold IMT Influence Weaning?
Patients under threshold IMT show better conditions to weaning from mechanical ventilation than the control group.
- Trial name
- NCT00851617
- Testing
- Threshold® IMT
- Where
- Brazil
- Volunteers
- 92 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Ventilator Dependent
Short Effects of SIMT and EM in Prolonged Mechanically Ventilated Patients
Using mechanical ventilation for more than 18 hours can affect respiratory muscle and postural muscle control, making it difficult to wean off the ventilator and reducing mobility. The aim of this study is to: 1.
- Trial name
- NCT06368089
- Testing
- Inspiratory muscle training (IMT) group, Early mobilization (EM) group
- Where
- Thailand
- Volunteers
- 46 people
- Sponsor
- Prince of Songkla University
Pneumonia, Ventilator-Associated, Coronavirus Infection
Convalescent Antibodies Infusion in Critically Ill COVID 19 Patients
The 2019 outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2 or COVID 19), which originated in Wuhan, China, has become a major concern all over the world.
- Trial name
- NCT04346589
- Testing
- Anti-coronavirus antibodies (immunoglobulins)obtained with DFPP from convalescent patients
- Where
- 5 sites in Italy
- Volunteers
- 9 people
- Sponsor
- A.O. Ospedale Papa Giovanni XXIII
Oral Infection, Ventilator-associated Pneumonia
Evaluating the Effectiveness of the Tongue Cleaner in Critical Patients
The concern with oral infection and its systemic repercussions is old, many studies have been undertaken to establish this relationship more precisely.
- Trial name
- NCT01294943
- Testing
- Tongue cleaner
- Where
- Brazil
- Volunteers
- 50 people
- Sponsor
- University of Sao Paulo
Tracheostomy, Mechanical Ventilation
Speech Effects of a Speaking Valve Versus External Positive End-expiratory Pressure (PEEP) in Tracheostomized Ventilator-Dependent Neuromuscular Patients
Background: Many patients with respiratory failure related to neuromuscular disease receive chronic invasive ventilation through a tracheostomy.
- Trial name
- NCT00978783
- Testing
- Passy Muir Valve, Positive end expiratory pressure
- Where
- France
- Volunteers
- 10 people
- Sponsor
- University of Versailles
Mechanical Ventilation, Difficult Intubation
The Effect of Semi-recumbent Position With Exercise Training on Long-term Ventilator-dependent Patients
Prolonged mechanical ventilation patients rely on medical expenses per year had increased by nearly 20 billion in 15 years, so it is worthwhile to explore how to improve the respiratory function and even their quality of life of…
- Conditions
- Mechanical Ventilation, Difficult Intubation, Position, Exercise
- Trial name
- NCT04822831
- Testing
- 45 Degree Semi-recumbent Position With Upper Limb Exercise Training, no 45 Degree Semi-recumbent Position With Upper Limb Exercise Training
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Taoyuan General Hospital
Respiratory Failure
Effect of Inspiratory Muscle Training on Duration of Mechanical Ventilation Support
A growing body of knowledge has documented that the diaphragm, the primary muscle of breathing, atrophies and weakens within days of instituting mechanical ventilation support.
- Trial name
- NCT01108575
- Testing
- IMST
- Where
- United States
- Volunteers
- 76 people
- Sponsor
- University of Florida
Neurosurgical Procedures, Neurosurgical Patients
Prolonged Mechanical Ventilation in Neurosurgical Patients:
The study was carried out at the neurosurgical operating theater and neurosurgical intensive care unit, Maharaj Nakorn Chiang Mai University-Hospital.
- Conditions
- Neurosurgical Procedures, Neurosurgical Patients, Prolonged Mechanical Ventilation
- Trial name
- NCT06591624
- Testing
- Prolonged Mechanical Ventilation, remain intubation after surgery
- Where
- Thailand
- Volunteers
- 340 people
- Sponsor
- Chiang Mai University
Respiratory Failure, Communication Disorders
Early Speaking Valve in Ventilator Weaning: Effects on Communication, Depression, and Quality of Life
This study evaluates the impact of early tracheostomy speaking valve intervention on communication ability, depression levels, and quality of life in ventilator-dependent patients during the weaning phase.
- Conditions
- Respiratory Failure, Communication Disorders, Depression, Quality of Life
- Trial name
- NCT07005596
- Testing
- Passy-Muir Speaking Valve, Standard Non-Verbal Communication Methods
- Volunteers
- 70 people
- Sponsor
- Far Eastern Memorial Hospital
Sleep Quality, Comfort
The Effects of Receiving Warm Footbath With Lavender Essential Oil on Sleep and Comfort
Purposes: Describe the background information and clinical characteristics of respirator-dependent patients, verify the sleep and comfort effects of respirator-dependent patients whether or not they receive a lavender essential…
- Trial name
- NCT06380933
- Testing
- experimental group
- Where
- Taiwan
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Dalin Tzu Chi General Hospital
Gastrostomy, Ventilatory Failure
Concomitant Bedside Percutaneous Tracheostomy and Ultrasound Gastrostomy
The goal of this research study is to assess the FDA approved technique for inserting a feeding tube (gastrostomy) along with a breathing tube (tracheostomy) for patients that cannot breathe or eat on their own in the ICU…
- Conditions
- Gastrostomy, Ventilatory Failure, Respiratory Failure
- Trial name
- TPUG (NCT05955534)
- Testing
- TPUG, PEG, PRG
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Bronchopulmonary Dysplasia
Pilot Study of Topical Steroid for Prevention of Chronic Lung Disease in Extremely Premature Infants.
A Pilot study to evaluate the safety and the efficacy of endotracheal instillation of pulmonary surfactant, with or without topical steroid (Budesonide), as a prophylactic treatment for Bronchopulmonary Dysplasia (a form of…
- Trial name
- NCT01268215
- Testing
- Infasurf, Pulmicort
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- East Carolina University
Neuromuscular Diseases, Respiration, Artificial
Quality of Life in Ventilator-dependant Neuromuscular Patients
This study aims at evaluating the quality of life of patients with slowly progressive neuromuscular disorders who are dependant on mechanical ventilation (daily usage ≥ 16h).
- Conditions
- Neuromuscular Diseases, Respiration, Artificial, Tracheostomy, Noninvasive Ventilation
- Trial name
- EqualVENT (NCT04652401)
- Where
- France
- Volunteers
- 119 people
- Sponsor
- Centre d'Investigation Clinique et Technologique 805
Failure to Wean, Respiratory Failure
Inspiratory Muscle Training in Ventilator Dependent Patients
The purpose of this study is to determine if inspiratory muscle strength training will increase the proportion of ventilator dependent patients weaned versus Sham treated patients.
- Conditions
- Failure to Wean, Respiratory Failure, Ventilator Dependent
- Trial name
- NCT00419458
- Testing
- inspiratory muscle strength training
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Rib Fractures, Thorax; Fracture
Surgical Stabilisation of Rib Fractures in Non-ventilated Patients
The aim of the study is to investigate the effect of surgical stabilisation of rib fractures on clinical outcomes in patients that are not dependent on mechanical ventilation at the time of the treatment decision.
- Trial name
- NCT06464289
- Testing
- Surgical stabilisation of rib fractures (SSRF), Non-operative management of rib fractures
- Where
- Germany
- Volunteers
- 35,974 people
- Sponsor
- University Hospital Muenster
Pulmonary Disease
The Efficacy of Pulmonary Rehabilitation Exercise in Home Care for the Non-invasive Ventilator-dependent Elderly With COPD
Pulmonary rehabilitation exercise is beneficial for individuals with chronic obstructive pulmonary disease (COPD). However, merely 30% patients know how to do the exercise correctly.
- Trial name
- NCT02836912
- Testing
- Exercise
- Volunteers
- 28 people
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Ventilator Dependency
The Impact of Inspiratory Muscle Strength Training
The study is a pre-post test with quasi experimental design. Forty-two intubated-adults who had been mechanically ventilated for more than 21 days were selected on the basis of inclusion criteria in respiratory care ward.
- Trial name
- IMT (NCT03997214)
- Testing
- inspiratory muscle strength training
- Where
- Taiwan
- Volunteers
- 43 people
- Sponsor
- Fooyin University