Clinical trials: Ventilatory Physiology
Respiratory Disease
Does NIV-NAVA Improve Diaphragmatic Function in Preterm Infants
Non-Invasive Positive Pressure Ventilation (NIPPV) provides un-synchronized positive pressure and considered to be superior to nCPAP in preventing extubation failure.
- Trial name
- NCT05079412
- Testing
- Chest ultrasound
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- Mount Sinai Hospital, Canada
Chronic Obstructive Lung Disease
EFFECT OF COMBINED VIRTUAL REALITY-GUIDED BREATHING AND AEROBIC TRAINING ON VENTILATORY FUNCTION IN PATIENTS WITH COPD
This Single-blind, randomized controlled trial will evaluate the effects of 12 weeks of combined VR-guided diaphragmatic breathing (Flowborne) and VR-aerobic cycling (Kinneta) compared with conventional pulmonary rehabilitation…
- Trial name
- VR-COPD (NCT07885995)
- Testing
- VR-Based Pulmonary Rehabilitation Group, Conventional Pulmonary Rehabilitation Group
- Volunteers
- 60 people
- Sponsor
- Cairo University
Anxiety, Panic Disorder
Ventilatory Physiology in Children at Risk for Anxiety
The importance of the proposed research project derives from a steady accumulation of research findings on the relationship between respiration and anxiety.
- Trial name
- NCT00101777
- Where
- United States
- Volunteers
- 479 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Respiratory Distress Syndrome, Adult
Effect of Positive Expiratory Pressure on Right Ventricular Function in Patients With Respiratory Distress Syndrome
The objective of this study is to analyze by trans-oesophageal echocardiography the effect on the right ventricle of positive expiratory pressure (PEP) level variations with constant plate pressure among patients with syndrome of…
- Trial name
- NCT00236262
- Testing
- ventilatory strategies with pressure
- Where
- France
- Volunteers
- 15 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Patents With Normal VQ/SPECT
Normal Ventilatory and Perfusion Pulmonary Function in TEMP
Ventilation - perfusion SPECT is attractive for lung function assessement. Unfortunately, it is very difficult to delineate normal to abnormal areas because of physiological uptake heterogeneity.
- Trial name
- 3DSPECSTAT (NCT04332406)
- Where
- France
- Volunteers
- 96 people
- Sponsor
- University Hospital, Brest
Pulmonary Edema Cardiac Cause
HF vs NIV in Acute Cardiogenic Pulmonary Edema
The study's primary aim is to compare the effects of two different ventilation modalities, non-invasive positive-pressure ventilation (NPPV) and high-flow nasal cannulae (HFNC), in the acute cardiogenic pulmonary edema (ACPE)…
- Trial name
- HFvsNIV (NCT05989139)
- Testing
- NPPV/HFNC, HFNC/NPPV
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Tetralogy of Fallot (TOF), Adults With Repaired Tetralogy of Fallot
Effect of Exercises on Ventilatory Function in Adult With TOF
The goal of this clinical trial is to learn if combined inspiratory muscle training and aerobic exercise can improve ventilatory function in adults with repaired Tetralogy of Fallot (TOF).
- Trial name
- NCT07326228
- Testing
- aerobic exercise, respiratory muscle training
- Volunteers
- 60 people
- Sponsor
- Cairo University
Central Obesity, Ventilatory Function
Effect of Thoracic Mobilization in People With Central Obesity
The goal of this clinical trial is to learn whether Mulligan thoracic mobilization in extension improves ventilatory functions and chest wall expansion in adults with central obesity.
- Trial name
- NCT07718178
- Testing
- Mulligan Thoracic Mobilization, low carbohydrate, Aerobic Exercise
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
COPD, PAD
Effect of Breather in COPD Patients With Intermittent Claudication
The aim of this study To show the effect of breather on ventilatory and vascular function in COPD patient with intermittent claudication.
- Trial name
- NCT06529185
- Testing
- The BREATHER, pharmacological treatment
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Copd
Impact of Long-acting Bronchodilator- -Corticoid Inhaled Therapy on Ventilation, Lung Function and Breathlessness
Multicentre, prospective, non-randomised, single-arm, open label, mechanistic study to investigate the mechanism of action of BGF 160 on ventilation pattern complexity and variability
- Trial name
- VARI-OSCIL (NCT06110403)
- Testing
- TRIXEO AEROSPHERE
- Where
- France
- Volunteers
- 35 people
- Sponsor
- University Hospital, Lille
Elective Cardiac Surgical Patients
Ventilatory Strategies After Cardiopulmonary Bypass Evaluated by Electrical Impedance Tomography
Pulmonary complications after cardiac surgeries are common. It is one of the most crucial concerns of cardiac surgeons and anesthesiologists.
- Trial name
- NCT04813250
- Testing
- ventilation mode setting
- Where
- Taiwan
- Volunteers
- 50 people
- Sponsor
- National Defense Medical Center, Taiwan
Study the Effectiveness of Combined Manual Therapy and Pulmonary Exercises on Ventilatory Function in Patients with Restrictive Lung Diseases
Effectiveness of Combined Manual Therapy and Pulmonary Exercises on Ventilatory Function in Patients with Restrictive Lung Diseases
This research investigates the effect of selective manual therapy techniques on chest expansion, pulmonary function (FVC, FEV1, and FEV1/FVC ratio), and functional capacity, in restrictive lung disease patients.
- Trial name
- NCT06681701
- Testing
- Combined Manual Therapy and Pulmonary Exercises
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- South Valley University
ICU Patients, Intubation
Pulmonary and Ventilatory Effects of Trigger Modulation in Intubated ICU
Pressure support ventilation allows intubated ICU patients to breathe spontaneously. Among specific settings, the adjustment of the trigger value (or threshold for triggering the ventilator) has not been explored to date.
- Conditions
- ICU Patients, Intubation, Spontaneously Breathing, Pulmonary Function
- Trial name
- Trigger (NCT04041817)
- Testing
- Trigger setting of pressure support ventilation
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Clermont-Ferrand
Covid19, Dyspnea
Understanding Exertional Dyspnea and Exercise Intolerance in COVID-19
A novel corona virus emerged in 2019 causing Corona Virus Disease 2019 (covid-19). In one year more than 80 000 000 cases worldwide were documented.
- Trial name
- NCT04732663
- Testing
- No Intervention
- Where
- Canada
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Cardiorespiratory Fitness, Metabolic Health
Validation of a Novel Incremental Step Test for Assessment of Cardiopulmonary Fitness and Ventilatory Thresholds in Adults
The purpose of this single-group diagnostic validation and test-retest reliability study is to determine whether a novel Incremental Step Test (IST) can accurately assess cardiorespiratory fitness and ventilatory thresholds in…
- Conditions
- Cardiorespiratory Fitness, Metabolic Health, Cardiac Function, Pulmonary Function
- Trial name
- VALID-IST (NCT07829003)
- Testing
- Cardiopulmonary Exercise Test, Incremental Step Test
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Heriot-Watt University
Pulmonary Function, Nutrition, Healthy
Effects of Beetroot Juice Intake on Performance and Physiological Parameters
This study was a randomized, double-blind, crossover design for 3 weeks. In the first week, a researcher explained all the experimental procedures to the participants.
- Trial name
- NCT06073275
- Testing
- Beetroot juice ingestion
- Where
- Spain
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Campus docent Sant Joan de Déu-Universitat de Barcelona
Cigarette Smoking, Impaired Ventilatory Function
Effect of Pyramidal Aerobic Training on Ventilatory Function in Cigarette Smokers
Statement of the problem: Does the pyramidal aerobic training affect ventilatory function parameters in smokers? Null hypothesis: Pyramidal aerobic training has no significant effect on ventilatory function parameters (such as…
- Conditions
- Cigarette Smoking, Impaired Ventilatory Function, Respiratory Function in Adult Smokers
- Trial name
- NCT07765485
- Testing
- Pyramidal Aerobic Training
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Spinal Cord Injuries
Improving Ventilatory Capacity in Those With Chronic High Level SCI
The purpose of this study is to find out if taking the drug Buspar will increase breathing capacity in individuals with spinal cord injuries.
- Trial name
- NCT05041322
- Testing
- Buspirone
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Spaulding Rehabilitation Hospital
Exercise Physiology, Ventilatory Threshold
Modality-Specific Heart Rate Differences at Ventilatory Thresholds During Unified Ramp Testing
The purpose of this study was to investigate the heart rate bias between cycling and treadmill exercise at ventilatory thresholds. This was a randomized crossover trial involving 23 healthy participants.
- Conditions
- Exercise Physiology, Ventilatory Threshold, Heart Rate, Cycling and Treadmill Exercise
- Trial name
- NCT07718594
- Testing
- Cycle Ergometer CPET, Motorized Treadmill CPET (Porszász Protocol)
- Where
- Taiwan
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Cathay General Hospital
Ventilatory Defect
Specific Inspiratory Muscle Training (SIMT)in the Patients With Ventilatory Dependence
Prolong mechanical ventilation cause to respiratory muscle weakness and high risk to weaning failure,the investigators hypothesize that 1.
- Trial name
- SIMT (NCT00792441)
- Testing
- intervention group
- Where
- Thailand
- Volunteers
- 20 people
- Sponsor
- Saikaew Chuachan