Clinical trials: Ventral Hernias
Ventral Hernia, Incisional Hernia
The Impact of Abdominal Wall Reconstruction on Abdominal Wall Tension and Intra-Abdominal Pressure
This is a prospective cohort study. Patients have an incisional or parastomal hernia with >20 cm fascial defect on pre-operative imaging who will undergo an anticipated open bilateral transversus abdominis release with…
- Conditions
- Ventral Hernia, Incisional Hernia, Parastomal Hernia
- Trial name
- NCT06575166
- Testing
- Abdominal wall tension, Intra-abdominal pressure
- Where
- United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Hernia
CT and Radiologist RCT
The use of computed tomography (CT) imaging is rapidly increasing in healthcare. Despite physicians' growing reliance on radiological assessments, however, the reliability and accuracy of reads are highly variable.
- Trial name
- NCT03121131
- Testing
- Clinical Exam Findings, Inaccurate Clinical Exam Findings, No clinical exam findings
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Hernia, Ventral, Hernia, Inguinal
Ventral or Inguinal Hernia, Robotically Repaired With OviTex Mesh
This study is designed to evaluate the post-operative complications and hernia recurrence following the use of OviTex in subjects with ventral or inguinal hernias.
- Trial name
- BRAVOII (NCT04779918)
- Testing
- OviTex Reinforced Tissue Matrix
- Where
- 10 sites in United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Tela Bio Inc
Cholecystitis, Inguinal Hernia, Direct
No Need for Neuromuscular Blockade in Daycase Laparoscopic Surgery
This study analyse the need for neuromuscular blockade in consecutive routine laparoscopic procedures without standard use of neuromuscular blockade in an ambulatory laparoscopic surgery setting and analyse specific reasons for…
- Conditions
- Cholecystitis, Inguinal Hernia, Direct, Umbilical Hernia
- Trial name
- NCT02782832
- Volunteers
- 1,245 people, healthy volunteers welcome
- Sponsor
- Hvidovre University Hospital
Postoperative Cognitive Impairment, Optic Nerve Sheath Edema
Effect of Different Ventilation Modes on POCD in Elderly Patients with Abdominal Wall Hernia
The purpose of this clinical trial is to understand the effect of different ventilation patterns during surgery on postoperative cognitive impairment in elderly patients with abdominal wall hernias.
- Trial name
- NCT06764745
- Testing
- PC Ventilation Modes, VC Ventilation Modes, PRVC Ventilation Modes
- Where
- China
- Volunteers
- 471 people, healthy volunteers welcome
- Sponsor
- Inner Mongolia University of Science and Technology
Incisional Hernia of Anterior Abdominal Wall
Study on the Efficacy of Prophylactic on Lay Mesh in Preventing Post-operative Hernia in Liver Transplant Patients
Study Design: Single-blinded, randomized, prospective clinical trial. Study Population: End-stage liver disease patients' candidates for liver transplantation.
- Trial name
- NCT04512469
- Testing
- Low molecular weight mesh
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Ventral Hernia
Repair of Large Incisional Hernias - To Drain or Not to Drain Randomised Clinical Trial
The aim of this study was to perform a randomised clinical trial comparing the use of closed-suction tubular drains and progressive tension sutures in individuals with large incisional hernias subjected to onlay mesh repair to…
- Trial name
- NCT02163460
- Testing
- Drain, Progressive Tension Sutures
- Where
- Brazil
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Universidade Estadual do Oeste do Paraná
Abdominal Wall Hernia
Preoperative Weight Loss for Open Abdominal Wall Reconstruction
The goal of this randomized controlled trial is to compare preoperative intensive weight management to upfront surgery in obese patients undergoing complex abdominal wall reconstruction.
- Trial name
- NCT05925959
- Testing
- Preoperative Weight Management Program
- Where
- 2 sites in United States
- Volunteers
- 258 people, healthy volunteers welcome
- Sponsor
- Benjamin T. Miller
Hernia, Abdominal, Hernia,Ventral
Comparison of Two Mesh/Fixation Concepts for Laparoscopic Ventral and Incisional Hernia Repair
This is a monocenter randomized controlled trial comparing two systems of mesh and fixation device for the laparoscopic ventral and incisional hernia repair with respect to pain.
- Trial name
- NCT02233569
- Testing
- Intraperitoneal onlay mesh (IPOM) repair with the use of Phisiomesh implant and Securestrap fixation device., Intraperitoneal onlay mesh (IPOM) repair with the use of Ventralight ST implant with SorbaFix fixation device., Ventralight ST implant
- Where
- Poland
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Polish Hernia Study Group
Ventral Hernia, Abdominal Wall Defect
Intraoperative Biomechanics in Complex Abdominal Wall Reconstruction
Background: A detailed study of the biomechanical changes before and after abdominal wall reconstruction (AWR) has not been performed.
- Trial name
- NCT03296475
- Testing
- Abdominal Wall Closure Force (N).
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University College, London
Ventral Hernia
Comparative Study of Biologic Mesh Versus Repair With Component Separation.
The purpose of this study is to compare open abdominal incisional hernia repair using XenMATRIX biologic mesh versus repair with their own tissue.
- Trial name
- Davol (NCT01295125)
- Testing
- XenMATRIX mesh, Open abdominal ventral hernia repair
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- University Hospitals Cleveland Medical Center
Ventral Hernia, Umbilical Hernia
Prospective Study Of A Size Tailored Approach To Repair Umbilical And Epigastric Primary Ventral Hernias
Primary ventral hernias, such as umbilical and epigastric hernias, are best repaired with abdominal wall reinforcement by mesh implantation.
- Conditions
- Ventral Hernia, Umbilical Hernia, Epigastric Hernia
- Trial name
- SITUP (NCT01639118)
- Where
- Belgium
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Algemeen Ziekenhuis Maria Middelares
Hernia, Ventral
Transverse Abdominal Plane Anesthesia for Abdominal Wall Reconstruction
The aim of this study is to evaluate the short-term postoperative outcomes in the abdominal wall reconstruction population using an intraoperative local anesthetic infusion.
- Trial name
- NCT02274077
- Testing
- EXPAREL, Normal Saline
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Chester Mays
Ventral Hernia
Video-based Collaborative Learning to Improve Ventral Hernia Repair
Recent studies demonstrate the critical role of individual surgeon performance, including both the approach they take to an operation as well as their technical skill, in determining patient outcomes.
- Trial name
- NCT04173884
- Testing
- Coaching, Constructive Feedback
- Where
- United States
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Ventral Hernia, Umbilical Hernia
Case-control Study of Mesh-infection After a Size Tailored Hernia Repair With C-Qur V-Patch
Ventral hernias, such as umbilical, epigastric and trocar-site hernias, are best repaired with abdominal wall reinforcement by mesh implantation.
- Conditions
- Ventral Hernia, Umbilical Hernia, Epigastric Hernia, Trocar-site Hernia
- Trial name
- Re-SITUP (NCT01761708)
- Testing
- primary ventral hernia repair with mesh
- Where
- Belgium
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Algemeen Ziekenhuis Maria Middelares
Ventral Hernia
Reoperation Rate Versus Clinical Recurrence After Ventral Hernia Repair
The risk for recurrence after ventral hernia repair is often based on reoperation rates with short follow-up rather than recurrences identified by clinical examinations.
- Trial name
- NCT01325246
- Where
- Denmark
- Volunteers
- 945 people, healthy volunteers welcome
- Sponsor
- Zealand University Hospital
Ventral Hernia
Robotic Versus Open Ventral Hernia Repair
This is a randomized trial comparing open retromuscular ventral hernia repair to robotic retromuscular ventral hernia repair.
- Trial name
- ROVHR (NCT05472987)
- Testing
- Ventral Hernia Repair
- Where
- 5 sites in United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Lucas Beffa
Ventral Hernia
Regional Differences In Indication for Ventral Hernia Repair
The aim of the present study is to investigate whether there are differences in indication for ventral hernia repair and surgical approach among hernia surgeons from different geographical regions of Denmark.
- Trial name
- NCT02263625
- Where
- Denmark
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Zealand University Hospital
Ventral Hernia
Anovo Surgical System in Ventral Hernia
The study is aimed to clinically assess the AnovoTM Surgical System in ventral hernia procedures. Extensive preclinical testing of the system's integrity and safety has been performed to assure adequate safety for this trial.
- Trial name
- CLEVER (NCT06457971)
- Testing
- Robotic Ventral Hernia Repair
- Where
- 2 sites in Belgium, Israel
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Momentis Surgical
Ventral Hernia, Umbilical Hernia
Comparing eTEP and Laparoscopic Intraperitoneal Onlay Mesh (IPOM) for Ventral Hernias
Ventral hernias can be repaired using a variety of techniques, with smaller defects often being amenable to minimally invasive surgical (MIS) approaches.
- Conditions
- Ventral Hernia, Umbilical Hernia, Epigastric Hernia
- Trial name
- NCT04150796
- Testing
- Ventral Hernia Repair
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic