Clinical trials: Ventricular Repolarization, open to volunteers
Premature Ovarian Insufficiency
Ventricular Repolarization in Patients With Premature Ovarian Insufficiency (QTIOP)
Ventricular repolarization, measured by corrected QT interval (QTc), is influenced by sex hormones. A QTc above 460msec predisposes to the risk of "torsades-de-pointes"(TdP).
- Trial name
- QTIOP (NCT04167033)
- Testing
- Hormone replacement therapy:effect on ventricular repolarization, ECG
- Where
- 3 sites in France
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Inherited Cardiac Arrythmias, Long QT Syndrome (LQTS)
Derivation of Human Induced Pluripotent Stem (iPS) Cells to Heritable Cardiac Arrhythmias
Human induced pluripotent stem cells (hiPSCs) have driven a paradigm shift in the modeling of human disease; the ability to reprogram patient-specific cells holds the promise of an enhanced understanding of disease mechanisms and…
- Conditions
- Inherited Cardiac Arrythmias, Long QT Syndrome (LQTS), Brugada Syndrome (BrS), Catecholaminergic Polymorphic Ventricular Tachycardia (CPVT)
- Trial name
- NCT02413450
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Ventricular Tachycardia
Ventricular Tachycardia Mechanisms
The purpose of this study is to understand why certain hearts have ventricular arrhythmias and help identify areas of the heart that cause arrhythmias.
- Trial name
- NCT05478213
- Testing
- Monophasic Action Potential (MAP) Catheter
- Where
- 3 sites in United States
- Volunteers
- 10 people
- Sponsor
- Emory University
Ventricular Tachycardia Ablation
Repolarization and Activation Mapping in Ventricular Tachycardia Ablation: the REDEMPTION Study
The aim of this study is to prospectively evaluate a novel sinus rhythm mapping strategy for ventricular tachycardia (VT) ablation based on combined ventricular repolarization and activation (depolarization) mapping…
- Trial name
- REDEMPTION (NCT06765746)
- Testing
- Ventricular tachycardia ablation
- Volunteers
- 40 people
- Sponsor
- Universitair Ziekenhuis Brussel
Hypertension, Blood Pressure Monitoring, Ambulatory
Nocturnal Blood Pressure Dipping and Ventricular Repolarization in Hypertension
The primary aim is to determine whether non-dipping status is associated with adverse repolarization markers and impaired myocardial mechanics compared to dipper hypertensive patients.
- Conditions
- Hypertension, Blood Pressure Monitoring, Ambulatory, Circadian Rhythm, Electrocardiography
- Trial name
- NBP-DIP (NCT07200856)
- Testing
- Nocturnal Blood Pressure Dipping
- Volunteers
- 140 people
- Sponsor
- Assiut University
Ventricular Arrythmia
China Inherited Ventricular Arrhythmias Registry
This is an observational, prospective, multi-center registry, aiming at building a risk stratification for malignant inherited ventricular arrhythmias, including Brugada syndrome(Brs)、Long QT syndrome(LQTS)、Short QT…
- Trial name
- NCT03880708
- Where
- China
- Volunteers
- 500 people
- Sponsor
- China National Center for Cardiovascular Diseases
Post COVID-19, Ventricular Repolarization
Changes in Electrocardiographic (ECG) Ventricular Repolarization and Transthoracic Impedance Cardiography (ICG) Parameters in Patients with COVID-19 and After the Disease: Persistence and Prognostic Significance of These Changes
The aim of this study is to determine the relationship between changes in resting electrocardiography (ECG) ventricular repolarization parameters, transthoracic impedance cardiography (ICG) parameters, and COVID-19, to assess the…
- Conditions
- Post COVID-19, Ventricular Repolarization, Arrhythmias, Impedance Cradiography
- Trial name
- NCT06674278
- Volunteers
- 215 people
- Sponsor
- Lithuanian University of Health Sciences
Cardiac Disease, Ventricular Arrythmia
Development of an Artificial Intelligence Algorithm to Detect Pathological Repolarization Disorders on the ECG and the Risk of Ventricular Arrhythmias
Torsades de Pointes (TdP) are potentially fatal ventricular arrhythmias that are promoted by prolonged ventricular repolarization (Long QT, LQT).
- Trial name
- DEEPECG4U (NCT05829993)
- Where
- France
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris