Clinical trials: Vertebra Compression Fracture
Vertebral Compression Fracture, Myeloma
The Value of Systematic Biopsies During Vertebroplasty for the Treatment of Osteoporotic Vertebral Fractures
Background : Vertebral fracture is the most common complication of osteoporosis. Vertebroplasty is a widespread treatment modality for osteoporotic vertebral fractures, providing consolidation, rapid pain relief and preventing…
- Conditions
- Vertebral Compression Fracture, Myeloma, Bone Metastases, Malignant Bone Tumour
- Trial name
- NCT06153576
- Where
- France
- Volunteers
- 1,120 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Spinal Fracture, Compression Fracture
Acupuncture Treatment for Vertebral Compression Fracture
Patients with vertebral compression fractures (VCF) may experience pain, limitation of daily activities, and various complications (e.g., insomnia, constipation, urinary infection, depression, diminished quality of life).
- Conditions
- Spinal Fracture, Compression Fracture, Fractures, Bone
- Trial name
- NCT03359941
- Testing
- acupuncture
- Where
- South Korea
- Volunteers
- 7 people
- Sponsor
- Korean Medicine Hospital of Pusan National University
Osteoporosis, Vertebral Fracture
Evaluation of Outcomes of DFine StabiliT Kyphoplasty in Vertebral Compression Fractures Due to Osteoporosis
This post-market surveillance research project consists of data collection at specified time points using standard questionnaire instruments to compare pain level, mobility and function pre and post procedure using the D-Fine…
- Trial name
- NCT01839682
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Cedars-Sinai Medical Center
Vertebral Body Compression Fractures
KAVIAR Study - Kyphoplasty And Vertebroplasty In the Augmentation and Restoration of Vertebral Body Compression Fractures
Patients with osteoporotic vertebral body compression fractures will be randomly assigned to treatment with balloon kyphoplasty or vertebroplasty.
- Trial name
- NCT00323609
- Testing
- Vertebroplasty, Kyphoplasty
- Where
- 26 sites in United States, Canada
- Volunteers
- 404 people
- Sponsor
- Medtronic Spine LLC
Back Pain
Tapentadol IR vs Oxycodone IR vs Placebo in Acute Pain From Vertebral Compression Fracture Associated With Osteoporosis
The purpose of this study is to determine the effectiveness and safety of tapentadol immediate release (IR) as compared with placebo and oxycodone IR in patients with acute pain caused by vertebral compression fractures (VCF)…
- Trial name
- NCT00771758
- Testing
- oxycodone IR, tapentadol IR
- Where
- 37 sites in United States
- Volunteers
- 108 people
- Sponsor
- Ortho-McNeil Janssen Scientific Affairs, LLC
Vertebral Compression Fracture, Kyphoplasty
Anesthesia for Percutaneous Kyphoplasty
The aim of this study was to compare ESP with conventional local infiltration anesthesia (CLIA) and extrapedicular infiltration anesthesia (EPIA) with respect to analgesic efficacy in patients underwent elective PKP for VCF.
- Trial name
- Kyphoplasty (NCT07091513)
- Testing
- group ESP
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Gulhane School of Medicine
Back Pain
To Evaluate Success of Cement Treatment of Spinal Compression Fractures
Patients with vertebral compression fracture will be treated cement injection into the spine and monitored using standard evaluations.
- Trial name
- NCT00166374
- Testing
- balloon kyphoplasty
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Mayo Clinic
Vertebral Body Compression Fractures (VCFs)
Medtronic SCORE Study - Study of Curette Use for Obtaining Restoration of Vertebral Body Anatomy in Balloon Kyphoplasty
The objective of this study is to measure the effect that the scraping and scoring of vertebral cancellous bone using the Kyphon® Curette has on vertebral body anatomy height restoration and angular deformity correction during a…
- Trial name
- MDTSCORE (NCT00810043)
- Testing
- Kyphon® Curette
- Where
- 13 sites in United States, Belgium and 1 more
- Volunteers
- 120 people
- Sponsor
- Medtronic Spine LLC
Vertebral Body Compression
Efficacy of Kyphoplasty With a New Intervertebral Expander
Balloon kyphoplasty is a well-established treatment option to achieve pain relief and to correct kyphotic deformity caused by osteoporotic vertebral compression fracture.
- Trial name
- NCT03521661
- Testing
- Kyphoplasty
- Volunteers
- 41 people
- Sponsor
- Mohammad ARAB MOTLAGH
Osteoporotic Vertebral Compression Fractures
Continuous Mobility and Physical Activity in Vertebroplasty vs Sham for Osteoporotic Vertebral Fracture
The aim of this clinical trial is to determine if vertebroplasty is an effective treatment for acute, painful vertebral fractures due to osteoporosis.
- Trial name
- VOPE2 COMPAS (NCT06776003)
- Testing
- Vertebroplasty
- Where
- Denmark
- Volunteers
- 64 people
- Sponsor
- Spine Centre of Southern Denmark
Vertebral Body Compression Fractures
Evaluating Vertebroplasty and Kyphoplasty for Reducing Trauma-related Fractures
The primary objective of this study is to compare the volume of injected ciment (polymethyl methacrylate) between a group of patients treated with vertebroplasty and a group of patients treated via kyphoplasty.
- Trial name
- NCT01402167
- Testing
- Kyphoplasty, Vertebroplasty
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Vertebra Compression Fracture
Monitoring of Fluoroscopy Time on the Dose Delivered to the Patient During Vertebral Cementoplasty Procedures
The interventional radiology department of the Strasbourg University Hospital performs approximately 1,000 vertebral cementoplasties per year.
- Trial name
- CIMVER (NCT06174077)
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Strasbourg, France
Compression Fracture Spine, Osteoporosis Fracture
Postrual Reduction With Pillow in Osteoporotic Vertebral Fracture
Vertebroplasty in the symptomatic osteoporotic vertebral fracture has become increasingly popular. However, there have been some limitations in restoring the height of the collapsed vertebrae and in preventing the leaking of…
- Trial name
- NCT03451305
- Testing
- Pillow
- Where
- Taiwan
- Volunteers
- 120 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Multiple Myeloma
Vertebral Augmentation With Kyphoplasty vs Nonsurgical Mgmt for Vertebral Body Compression Fractures
The purpose of this study is to find out how balloon kyphoplasty (surgical repair of the patient's fracture using balloons and bone cement) compares to non-surgical treatment in reducing vertebral compression fractures while…
- Trial name
- NCT01175278
- Testing
- Vertebral Augmentation with Balloon Kyphoplasty, Non-surgical Treatment
- Sponsor
- H. Lee Moffitt Cancer Center and Research Institute
Denosumab Allergy, Zoledronic Acid Allergy
Denosumab vs Zoledronate After Vertebroplasty
Osteoporotic vertebral compression fracture (OVCF) patients had a proportion of secondary fractures after percutaneous vertebroplasty (PVP).
- Trial name
- NCT05598606
- Testing
- Denosumab Injection, Zoledronate
- Where
- China
- Volunteers
- 75 people
- Sponsor
- Shenzhen People's Hospital
Denosumab Allergy
Denosumab vs Alendronate After Vertebroplasty
Osteoporotic vertebral compression fracture (OVCF) patients had a proportion of secondary fractures after percutaneous vertebroplasty (PVP).
- Trial name
- NCT05662358
- Testing
- Denosumab, Alendronate
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Shenzhen People's Hospital
Osteoporotic Fractures, Vertebral Fracture
Percutaneous Vertebroplasty Vs. Sham for Osteoporotic Vertebral Compression Fractures Focusing on Pain and Economy.
The purpose of this randomized double-blind clinical trial is to determine the efficacy of percutaneous vertebroplasty (PVP) in relieving severe pain in patients with MRI-verified acute or sub-acute osteoporotic vertebral…
- Trial name
- VOPE2 (NCT06141187)
- Testing
- Vertebroplasty
- Where
- Denmark
- Volunteers
- 240 people
- Sponsor
- Spine Centre of Southern Denmark
Compression Fracture of Vertebral Body, Osteoporosis
Evaluation of Outcomes for Quality of Life and Activities of Daily Living for BKP in the Treatment of VCFs
The study objective is to collect and report 12-month outcomes pertaining to activities of daily living, quality of life, and safety parameters in a Medicare population to be treated with balloon kyphoplasty in the treatment of…
- Conditions
- Compression Fracture of Vertebral Body, Osteoporosis, Cancer
- Trial name
- EVOLVE (NCT01871519)
- Testing
- Balloon kyphoplasty
- Where
- 25 sites in United States
- Volunteers
- 354 people
- Sponsor
- Medtronic Spinal and Biologics
Lumbar Post-Laminectomy Syndrome, Chronic Low Back Pain
Determining the Prognostic Value of Continuous Intrathecal Infusion
The purpose of this study will be to determine the efficacy and the prognostic value of a continuous intrathecal prognostic infusion test in an in-hospital setting for selecting patients who would have better long term outcomes…
- Conditions
- Lumbar Post-Laminectomy Syndrome, Chronic Low Back Pain, Vertebral Compression Fracture, Failed Back Surgery Syndrome
- Trial name
- NCT03523000
- Testing
- Continuous intrathecal prognostic infusion test, Bupivacaine, Fentanyl
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- University Hospitals Cleveland Medical Center
OVCF Database, Cohort Study
Osteoporotic Vertebral Compression Fracture Cohort Study
The study aims to construct an early warning model for Osteoporotic Vertebral Compression Fracture (OVCF) by integrating TCM syndrome patterns with modern risk factors.
- Trial name
- NCT07321795
- Where
- 4 sites in China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Wangjing Hospital, China Academy of Chinese Medical Sciences