Clinical trials: Vertebral Compression Fracture, open to volunteers
Kyphoplasty, Vertebroplasty
A Prospective, Single-center, Observational Clinical Outcomes Study for Vertebral Compression Fractures Treated With the OsteoPearl Biological Allograft Implants
The primary objective of this observational study is to evaluate fracture stability through longitudinal assessment of subject-reported pain following treatment with the OsteoPearl Biological Allograft in men and women aged ≥50…
- Conditions
- Kyphoplasty, Vertebroplasty, Vertebral Compression Fracture, Allograft
- Trial name
- PEARL ONE (NCT07561489)
- Testing
- Allograft
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Lenoss Medical
BKP, Osteoporotic Vertebral Compression Fracture
Randomized Controlled Trial of Internal Fixation Reconstruction With Stent Screw in the Treatment of Kummell's Disease
This study is a multicenter, prospective, double-blind, randomized controlled trial using a parallel two-arm design to investigate whether the postoperative 6-month quality of life, vertebral stability, complication of patients…
- Conditions
- BKP, Osteoporotic Vertebral Compression Fracture, Kummell's Disease, Stent-screw-assisted Internal Fixation
- Trial name
- NCT06093087
- Testing
- SAIF, BKP
- Volunteers
- 70 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Osteoporotic Vertebral Compression Fractures, Vertebroplasty
Standardized Study Protocol of Percutaneous Vertebroplasty Based on Pedicle Nine-Grid Zoning Method
The goal of this clinical trial is to verify the safety and efficacy of the pedicle "Nine-grid Zoning Method" in assisting percutaneous vertebroplasty (PVP) for the treatment of lumbar osteoporotic vertebral compression fractures…
- Trial name
- NCT07616583
- Testing
- Nine-grid Area Division Method Assisted PVP, Traditional Standard Percutaneous Vertebroplasty (PVP)
- Where
- China
- Volunteers
- 68 people
- Sponsor
- Beijing Friendship Hospital
Vertebral Compression Fractures, Pathological Fracture
Prospective Evaluation of Therapeutic Combination in Treating Vertebral Compression Fractures
The purpose of this study is to collect clinical and radiographic outcomes in patients undergoing vertebroplasty procedures for the treatment of osteoporotic or pathological fractures of the vertebral body to understand the role…
- Conditions
- Vertebral Compression Fractures, Pathological Fracture, Facet Joint Arthropathy
- Trial name
- PROTECT (NCT06670404)
- Testing
- Vertebroplasty
- Where
- Switzerland
- Volunteers
- 130 people
- Sponsor
- Prof Nicolas Theumann
Clinical Decision Support System
Development and Application of a Clinical Decision Support System for Exercise Rehabilitation in Patients With Osteoporotic Vertebral Compression Fractures
This study aims to develop a clinical decision support system for exercise rehabilitation in patients with osteoporotic vertebral compression fractures, based on evidence-based recommendations for postoperative exercise…
- Trial name
- NCT07623304
- Testing
- Decision Support System: A clinical decision support system for exercise rehabilitation in patients with osteoporotic vertebral compression fractures, Basic Postoperative Care, Conventional Postoperative Care
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Jiawei Jiang
Osteoporosis, Osteoporotic Vertebral Compression Fractures
Safety and Efficacy Clinical Trial of the Vessel-X® Bone Filling Container System
Osteoporotic vertebral compression fractures (OVCFs) are a common and serious complication of osteoporosis, particularly among elderly and postmenopausal patients.
- Trial name
- CMT-VX (NCT07665424)
- Testing
- CMT Vessel-X® Bone Filling Container System, CMT Manual Orthopedic Surgical Instruments
- Where
- 2 sites in Taiwan
- Volunteers
- 146 people
- Sponsor
- Juin-Hong Cherng
Thoracolumbar Low-energy Vertebral Compression Fractures
Large-Scale Evaluation of a Clinical Decision Tree for the Management of Low-Energy Thoracic and Lumbar Vertebral Compression Fractures.
Percutaneous vertebroplasty is widely used for low-energy vertebral compression fractures, but its clinical benefits remain debated.
- Trial name
- PALMTREE (NCT07706439)
- Where
- France
- Volunteers
- 400 people
- Sponsor
- University Hospital, Grenoble
Osteoporotic Vertebral Compression Fractures
Continuous Mobility and Physical Activity in Vertebroplasty vs Sham for Osteoporotic Vertebral Fracture
The aim of this clinical trial is to determine if vertebroplasty is an effective treatment for acute, painful vertebral fractures due to osteoporosis.
- Trial name
- VOPE2 COMPAS (NCT06776003)
- Testing
- Vertebroplasty
- Where
- Denmark
- Volunteers
- 64 people
- Sponsor
- Spine Centre of Southern Denmark
Osteoporotic Fractures, Vertebral Fracture
Percutaneous Vertebroplasty Vs. Sham for Osteoporotic Vertebral Compression Fractures Focusing on Pain and Economy.
The purpose of this randomized double-blind clinical trial is to determine the efficacy of percutaneous vertebroplasty (PVP) in relieving severe pain in patients with MRI-verified acute or sub-acute osteoporotic vertebral…
- Trial name
- VOPE2 (NCT06141187)
- Testing
- Vertebroplasty
- Where
- Denmark
- Volunteers
- 240 people
- Sponsor
- Spine Centre of Southern Denmark
OVCF Database, Cohort Study
Osteoporotic Vertebral Compression Fracture Cohort Study
The study aims to construct an early warning model for Osteoporotic Vertebral Compression Fracture (OVCF) by integrating TCM syndrome patterns with modern risk factors.
- Trial name
- NCT07321795
- Where
- 4 sites in China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Wangjing Hospital, China Academy of Chinese Medical Sciences
Osteoporotic Vertebral Compression Fractures, Restrictive Pulmonary Disorders
Inspiratory Muscle Training After Vertebroplasty in Osteoporotic Fracture Patients
This study investigates the long-term effects of inspiratory muscle training (IMT) on pulmonary function, functional capacity, and quality of life in individuals with osteoporotic vertebral compression fractures who have…
- Conditions
- Osteoporotic Vertebral Compression Fractures, Restrictive Pulmonary Disorders, Inspiratory Muscle Weakness, Postoperative Pulmonary Function
- Trial name
- NCT07024095
- Testing
- Inspiratory Muscle Training (IMT), control group
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people
- Sponsor
- Istinye University
Spinal Metastases
Trial of Combined Radiotherapy and Vertebroplasty for Patients With Painful Metastatic Spinal Lesions
Since patients with spinal metastases are living longer, durable palliation with long-term tumor control are becoming increasingly important. EBRT results in durable local control of bone metastasis.
- Trial name
- NCT04242589
- Testing
- Radiotherapy, Vertebropladty
- Where
- Canada
- Volunteers
- 64 people
- Sponsor
- AHS Cancer Control Alberta
Vertebral Fracture, Compression Fracture
Spine Bone Cements Outcomes - Post Market Follow-up
A Post-Market Clinical Follow-Up (PMCF) Study to collect clinical data on safety and performance of all TEKNIMED Spine range of products: SPINEFIX, HIGH V+, OPACITY+ and F20 bone cements and mixing and injection systems, and all…
- Conditions
- Vertebral Fracture, Compression Fracture, Osteoporotic Fractures
- Trial name
- NCT06367582
- Testing
- Vertebroplasty (VP), Kyphoplasty (KP), Pedicular Screw Augmentation (PSA)
- Where
- 12 sites in France, Portugal and 2 more
- Volunteers
- 500 people
- Sponsor
- Teknimed
Unstable Osteoporotic Vertebral Compression Fractures
RCT on the Efficacy and Safety of Minimally Invasive SAIF Technique vs Spinal Fixation in Unstable Osteoporotic Vertebral Fractures
Osteoporotic vertebral fractures (OVF) represent a significant cause of morbidity, mortality, decreased level of function and quality of life.
- Trial name
- SAIF (NCT07071870)
- Testing
- Stent-screw Assisted Internal Fixation (SAIF), Surgical stabilization
- Where
- Switzerland
- Volunteers
- 140 people
- Sponsor
- Eva Koetsier MD PhD
Osteoporotic Fracture of Vertebra
Percutaneous Vertebral-disc Plasty for Thoracolumbar Very Severe Osteoporotic Vertebral Compression Fractures
Purpose: To compare the clinical outcomes and radiological parameters of patients undergoing percutaneous vertebroplasty (PVP) versus those undergoing percutaneous vertebral-disc plasty (PVDP) for back pain, segmental…
- Trial name
- NCT05519332
- Testing
- percutaneous vertebral-disc plasty
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Jiawei Jiang
Vertebral Compression Fracture
A Clinical Study Evaluating the Safety and Efficacy of the VCFix Spinal System for Treatment of Vertebral Compression Fractures
This study is being conducted to evaluate the safety and performance of the VCFix Spinal System, a medical device designed to treat certain types of spinal fractures called vertebral compression fractures (VCFs) in adults.
- Trial name
- EXPAND (NCT07301749)
- Testing
- VCFix Spinal System in stand-alone configuration
- Where
- 3 sites in France, Germany
- Volunteers
- 148 people
- Sponsor
- Amber Implants B.V.
Osteoporosis Fracture, Osteoporosis Vertebral
Development and Validation of a Postoperative Re-fracture Risk Model for Osteoporotic Spinal Fractures
In this project, IDEAL-IQ technology and PDFF and R2* image-based imaging methods are used to analyze the intrinsic relationship between preoperative vertebral bone marrow fat content, magnetic susceptibility properties of bone…
- Conditions
- Osteoporosis Fracture, Osteoporosis Vertebral, Compression Fracture, Perform PVP / PKP Treatment
- Trial name
- NCT06379243
- Testing
- PVP/PKP
- Where
- China
- Volunteers
- 560 people
- Sponsor
- The Seventh Affiliated Hospital of Sun Yat-sen University
Osteoporotic Vertebral Compression Fractures
CT-Based Deep Learning for Differentiating Acute and Chronic Osteoporotic Vertebral Compression Fractures
Osteoporotic vertebral compression fractures are common in older adults and may present as either acute or chronic fractures. Correctly distinguishing acute from chronic fractures is clinically important because treatment…
- Trial name
- CT-DL-OVCF (NCT07306858)
- Testing
- No Intervention (Observational Study)
- Where
- China
- Volunteers
- 276 people
- Sponsor
- Xin Fan