Clinical trials: Vertebral Fracture
Osteoporosis, Postmenopausal
The Prevalence of Osteoporotic Vertebral Compression Fractures (OVCF) in Korean Post Menopausal Women
This is an observational study to investigate the prevalence of osteoporotic fractures in post menopausal patients. Post menopausal patients who visit OS(orthopedic surgery) including GHs(general hospitals) and clinics will be…
- Trial name
- TOP (NCT01381588)
- Testing
- Fracture evaluation
- Where
- South Korea
- Volunteers
- 1,136 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Multiple Myeloma
To Compare Conservative Management Vs. Balloon Kyphoplasty in the Treatment of VCFs in Patients With Multiple Myeloma
The purpose of this study is to determine whether surgical treatment, balloon kyphoplasty is more effective compared to conservative treatment alone (sham procedure) when assessing clinical, translational, radiological \& patient…
- Trial name
- MELODY (NCT02732925)
- Testing
- Arm 2 Balloon Kyphoplasty, Conservative Management
- Where
- United Kingdom
- Volunteers
- 2 people
- Sponsor
- Royal National Orthopaedic Hospital NHS Trust
Denosumab Allergy
Denosumab vs Alendronate After Vertebroplasty
Osteoporotic vertebral compression fracture (OVCF) patients had a proportion of secondary fractures after percutaneous vertebroplasty (PVP).
- Trial name
- NCT05662358
- Testing
- Denosumab, Alendronate
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Shenzhen People's Hospital
Vertebral Compression Fracture
Comparison of Analgetic Therapies in Traumatic Vertebral Compression Fractures: Vertebroplasty vs Thermal Facet Ablation.
Study design: A prospective randomized study is performed and cases are selected where the indication for surgery is a vertebral compression fracture.
- Trial name
- NCT07507565
- Testing
- Thermal facet ablation, Vertebroplasty, Kyphoplasty
- Where
- Hungary
- Volunteers
- 1,000 people
- Sponsor
- Szeged University
Vertebral Compression Fracture
Vertebral Augmentation Using VCFix Spinal System in Stand-alone Configuration
This study will review the safety and possibility of the VCFix Spinal System. This is a proof-of-concept study and an initial review of the surgical procedure and how well the VCFix device works, to who that the VCFix is safe and…
- Trial name
- NCT07259811
- Testing
- VCFix Spinal System in stand-alone configuration
- Where
- 2 sites in Germany
- Volunteers
- 10 people
- Sponsor
- Amber Implants B.V.
Vertebral Fracture, Compression Fracture
Spine Bone Cements Outcomes - Post Market Follow-up
A Post-Market Clinical Follow-Up (PMCF) Study to collect clinical data on safety and performance of all TEKNIMED Spine range of products: SPINEFIX, HIGH V+, OPACITY+ and F20 bone cements and mixing and injection systems, and all…
- Conditions
- Vertebral Fracture, Compression Fracture, Osteoporotic Fractures
- Trial name
- NCT06367582
- Testing
- Vertebroplasty (VP), Kyphoplasty (KP), Pedicular Screw Augmentation (PSA)
- Where
- 12 sites in France, Portugal and 2 more
- Volunteers
- 500 people
- Sponsor
- Teknimed
Osteoporosis in Post-menopausal Women, Vertebral Body Fractures
Effect of Muscle Stiffness on Vertebral Fractures in Women Over 60
This study aims to assess the quality of lumbar and abdominal core muscles through elastography and evaluate its impact on vertebral fracture risk.
- Conditions
- Osteoporosis in Post-menopausal Women, Vertebral Body Fractures, Balance, Postural
- Trial name
- NCT06687889
- Testing
- Elastography Measurements, Bone Mineral Density Measurement (DEXA), Berg balance scale
- Where
- Turkey (Türkiye)
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
SPINAL Fracture
Minimally Invasive Surgical Management of Traumatic Spinopelvic Instability
the main aim of this study is to evaluate the results of performing minimally invasive surgical management for cases with traumatic spinopelvic instability and spinopelvic dissociation.
- Trial name
- NCT05321186
- Testing
- minimally invasive spinopelvic fixation
- Volunteers
- 20 people
- Sponsor
- Assiut University
Osteoporosis, Vertebral Fracture
Evaluation of the Impact of a Case-finding Strategy for Vertebral Fractures
Postmenopausal women with vertebral fractures (VFs) represent an important target for secondary fracture prevention, but few of these patients come for clinical attention.
- Trial name
- COSHIBA (NCT00463905)
- Testing
- Clinical assessment +/- radiography
- Where
- United Kingdom
- Volunteers
- 3,200 people, healthy volunteers welcome
- Sponsor
- University of Bristol
Osteoporosis, Fracture Risk Assessment
Five-Year CT Follow-Up of Vertebral Fracture Risk Using Opportunistic Osteoporosis Screening
This study evaluates whether opportunistic osteoporosis screening using routinely acquired computed tomography (CT) scans improves fracture risk prediction compared with guideline-recommended FRAX-based screening from age 50.
- Conditions
- Osteoporosis, Fracture Risk Assessment, Osteoporotic Fracture of Vertebra
- Trial name
- NCT07487688
- Testing
- Opportunistic osteoporosis screening
- Where
- Germany
- Volunteers
- 2,799 people
- Sponsor
- Technical University of Munich
Spinal Fractures, Osteoporosis
Vertebroplasty for the Treatment of Fractures Due to Osteoporosis
Vertebroplasty is a procedure used to stabilize broken vertebrae, the bones that form the spine. This study will evaluate the effectiveness of vertebroplasty for the treatment of fractures due to osteoporosis.
- Trial name
- NCT00068822
- Testing
- Percutaneous vertebroplasty
- Where
- United States
- Volunteers
- 131 people
- Sponsor
- Mayo Clinic
SPINAL Fracture
Comparative Study of Balloon Kyphoplasty and Conservative Treatment
This study will compare two treatments in acute stable traumatic vertebral fractures (types A1, A2 and A3.1 in MAGERL Classification). The two treatments are the followings: 1.
- Trial name
- TRAUMAA1-2-3 (NCT00749242)
- Testing
- orthopedic brace, balloon kyphoplasty
- Where
- France
- Volunteers
- 41 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Vertebral Body Fractures
Study on the Treatment of Osteoporotic Vertebral Fractures Using Vertebral Body Stenting
This is a randomized, controlled study to document and evaluate the clinical performance of the Vertebral Body Stenting (VBS) System in osteoporotic fractures of the thoracic and lumbar spine.
- Trial name
- NCT01847898
- Testing
- Vertebral Body Stenting (VBS), Balloon Kyphoplasty
- Where
- 5 sites in Austria, Germany
- Volunteers
- 100 people
- Sponsor
- Synthes GmbH
Back Pain
Tapentadol IR vs Oxycodone IR vs Placebo in Acute Pain From Vertebral Compression Fracture Associated With Osteoporosis
The purpose of this study is to determine the effectiveness and safety of tapentadol immediate release (IR) as compared with placebo and oxycodone IR in patients with acute pain caused by vertebral compression fractures (VCF)…
- Trial name
- NCT00771758
- Testing
- oxycodone IR, tapentadol IR
- Where
- 37 sites in United States
- Volunteers
- 108 people
- Sponsor
- Ortho-McNeil Janssen Scientific Affairs, LLC
Osteoporosis, Hyperkyphosis
Relationship Between Thoracic Hyperkyphosis and Fall Risk in Women with Fragility Vertebral Fractures
Multiple vertebral fragility fractures, one of the main complications of osteoporosis, are frequently associated with thoracic hyperkyphosis, which in turn leads to significant postural alterations.
- Conditions
- Osteoporosis, Hyperkyphosis, Vertebral Body Fracture
- Trial name
- NCT06842758
- Testing
- Rehabilitation Treatment, None Treatment
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- University of Palermo
Osteoporosis, Vertebral Fracture
Chiropractor Delivered Virtual Intervention After Vertebral frActure
This study will determine feasibility of a chiropractor delivered virtual intervention for individuals following osteoporotic vertebral fracture. This pilot trial will have two parallel groups with a 1:1 ratio.
- Trial name
- VIVA (NCT07288684)
- Testing
- VIVA
- Where
- Canada
- Volunteers
- 15 people
- Sponsor
- University of Waterloo
Vertebral Compression Fractures, Pathological Fracture
Prospective Evaluation of Therapeutic Combination in Treating Vertebral Compression Fractures
The purpose of this study is to collect clinical and radiographic outcomes in patients undergoing vertebroplasty procedures for the treatment of osteoporotic or pathological fractures of the vertebral body to understand the role…
- Conditions
- Vertebral Compression Fractures, Pathological Fracture, Facet Joint Arthropathy
- Trial name
- PROTECT (NCT06670404)
- Testing
- Vertebroplasty
- Where
- Switzerland
- Volunteers
- 130 people
- Sponsor
- Prof Nicolas Theumann
Osteoporosis, Vertebral Fracture
Patient Education With or Without Physical Training or Mindfulness and Medical Yoga in Established Spinal Osteoporosis
In the present feasibility and pilot study we aim to investigate the effect and safety of patient education with or without additional physical training or mindfulness/medical yoga in patients with manifest spinal osteoporosis…
- Trial name
- NCT05227976
- Testing
- Patient education (Theory), Physical training, Mindfulness and medical yoga in group
- Where
- Sweden
- Volunteers
- 31 people
- Sponsor
- University Hospital, Linkoeping
Vertebral Fracture, Balance
Evaluation of Balance and Gait Weight Distribution in Patients With Vertebral Column Fractures
Vertebral column fracture presents a significant warning of subsequent osteoporotic fracture and frequent falls. The presence of an osteoporotic vertebral fracture is also a predictor of further risk of vertebral and other…
- Conditions
- Vertebral Fracture, Balance, Gait, Unsteady
- Trial name
- NCT05010135
- Testing
- Zebris Gait System assessment for gait weight distribution + EMG evaluation of Quadriceps, Hamstrings, Tib Anterior and Calves + Positional Sense assessment
- Where
- Hong Kong
- Volunteers
- 80 people
- Sponsor
- Tung Wah College
Vertebral Fracture, Osteoporotic Fractures
CCEF in the Treatment of Acute VFFs: Randomized Controlled Trial
in recent years the search for therapeutic protocols that could enhance the VFFs healing, thus reducing bed rest-related complications and improving the quality of life of osteoporotic patients.
- Trial name
- NCT05803681
- Testing
- Capacitive Coupled Electric Fields (CCEF), Calssic clinical protocol
- Volunteers
- 70 people
- Sponsor
- University of Bari Aldo Moro