Clinical trials: Vertebral Metastases, open to volunteers
Vertebral Metastases, Vertebral Fracture
A Multicenter Prospective Observational Study on Vertebral Fracture Risk Stratification in Patients With Vertebral Metastases
Vertebral fracture is a common clinically significant skeletal related event in cancer patients. Stratification of patients diagnosed with one or more vertebral metastases according to the risk of pathological fracture is an…
- Trial name
- Valid-METASTRA (NCT06910618)
- Where
- 4 sites in Germany, Hungary and 2 more
- Volunteers
- 300 people
- Sponsor
- Buda Health Center
Spinal Metastasis
RELIEVE: Research on Effectiveness of Surgery and Radiotherapy on Relieving Spine Tumor Pain in Patients with Vertebral Metastases
This is a prospective, multicenter, observational study focusing on assessing and managing pain in patients with metastatic spinal tumors.
- Trial name
- RELIEVE (NCT06746103)
- Testing
- Surgery
- Volunteers
- 250 people
- Sponsor
- AO Foundation, AO Spine
Spinal Metastases, Local Control
Evaluate the Efficacy of Radiofrequency Ablation/Vertebroplasty with or Without SBRT for Treating Painful Spinal Vertebral Metastases
This study is a prospective, multicenter, open, practical, randomized controlled, non inferiority effect clinical study initiated by researchers, which aims to evaluate the clinical efficacy and safety of radiofrequency…
- Conditions
- Spinal Metastases, Local Control, Pain Cancer
- Trial name
- NCT06756087
- Testing
- Radiofrequency Ablation (RFA)/Vertebroplasty+Stereotactic Radiotherapy, Experimental
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
Epiduritis, Vertebral Bone Metastasis
Stereotactic Radiotherapy for SPinal Metastases With Limited Extent of Epidural Disease
This study evaluates a new radiation treatment approach for patients with cancer that has spread to the spine (vertebral metastases) and involves limited extension around the spinal cord without causing compression…
- Trial name
- SPEED-RT (NCT07656883)
- Testing
- Stereotactic Body Radiotherapy (SBRT), Conventional External Beam Radiotherapy
- Where
- 14 sites in France
- Volunteers
- 167 people
- Sponsor
- Institut Cancerologie de l'Ouest
Spinal Stenosis, SPINAL Fracture
Evaluation of the Evolution of Patient Care Within the Spinal Pathology Department
Spinal conditions are a major public health issue. Their management by surgical treatment is constantly improving and surgical procedures or implantable medical devices are experiencing significant progress.
- Conditions
- Spinal Stenosis, SPINAL Fracture, Vertebral Osteomyelitis, Vertebral Metastasis
- Trial name
- SPINDATA (NCT07627282)
- Testing
- self-administered questionnaire
- Where
- France
- Volunteers
- 15,000 people
- Sponsor
- University Hospital, Bordeaux
Metastases to Bone, Metastatic Breast Cancer
Tumoral Bone Strength Assessment by Numerical Simulation Using Quantitative CT : the MEKANOS Study
Osteolytic bone metastases and myeloma bone lesions are responsible of long bone and vertebral fractures leading to restricted mobility, surgery and medullar compression that severely alter quality of life and that have a huge…
- Conditions
- Metastases to Bone, Metastatic Breast Cancer, Metastatic NSCLC
- Trial name
- MEKANOS (NCT04170634)
- Testing
- Evaluation of the fracture risk using data from routine qCT (quantitative Computed Tomography) scan and numerical simulation
- Where
- 12 sites in France
- Volunteers
- 220 people
- Sponsor
- Hospices Civils de Lyon
Bone Cancer Metastatic, Radiofrequency Ablation
Effectiveness Of Radiofrequency Ablation And Stabilization In Metastatic Spine Lesions By Positron Emission Computed Tomography (PET-CT) Confirmation
This pilot study will try to demonstrate metabolic changes in spine lesions treated by Augmentation and Ablation, according to existing standards of practice.
- Conditions
- Bone Cancer Metastatic, Radiofrequency Ablation, Spine Metastases, Vertebral Metastasis
- Trial name
- ABLASPINE (NCT06716294)
- Testing
- Radiofrequency Ablation and Bone Augmentation
- Where
- Greece
- Volunteers
- 16 people
- Sponsor
- National and Kapodistrian University of Athens
Spine Metastases, Spine Stereotactic Radiosurgery (sSRS)
Single- vs. Two-Fraction Spine Stereotactic Radiosurgery for the Treatment of Vertebral Metastases
Spine radiosurgery (SRS) utilizes advanced treatment planning with focused x-rays to deliver one to four high dose treatments to the spine to help relieve pain and/or neurologic symptoms.
- Trial name
- NCT04218617
- Testing
- Diagnostic MRI, Planning MRI, Simulation CT
- Where
- United States
- Volunteers
- 130 people
- Sponsor
- Case Comprehensive Cancer Center