Clinical trials: Vertex Presentation
Invasive Breast Cancer
Axillary Lymph Node Status After Completion of Preoperative Neoadjuvant Systemic Chemotherapy in Patients
The purpose of the present proposed clinical trial will be to assess the utility of SLN mapping and biopsy for predicting the final axillary status after completion of preoperative neoadjuvant systemic chemotherapy in patients…
- Trial name
- NCT00507611
- Testing
- Sentinel node mapping
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Stephen Povoski
Breast Cancer With Low to Intermediate HER2 Expression
Efficacy and Safety Study of NeuVax™ (Nelipepimut-S or E75) Vaccine to Prevent Breast Cancer Recurrence
Purpose of this trial: 1. To assess the efficacy and safety of NeuVax™ administered with adjuvant Leukine® (sargramostim, GM-CSF). 2. To evaluate and compare the disease free survival (DFS) in the vaccinated and control subjects.
- Trial name
- PRESENT (NCT01479244)
- Testing
- NeuVax™ vaccine, Leukine® (sargramostim, GM-CSF) and water for injection
- Where
- 197 sites in United States, Bulgaria and 11 more
- Volunteers
- 758 people
- Sponsor
- Galena Biopharma, Inc.
Non-cephalic Presentation, Inhalation of Nitrous Oxide
Open Randomized Controlled Trial to Evaluate the Efficacy and Safety of Remifentanil Versus Nitrous Oxide in External Cephalic Version at Term in Singleton Pregnancy in Breech Presentation
Objectives: The objective is to demonstrate the superiority of remifentanil versus nitrous oxide as adjuvant analgesic treatment to increase the chances of success of external cephalic version in the management of non-cephalic…
- Conditions
- Non-cephalic Presentation, Inhalation of Nitrous Oxide, Pregnancy Complications, Complications; Cesarean Section
- Trial name
- REMIVER (NCT01735669)
- Testing
- Remifentanil, Nitrous Oxide
- Where
- Spain
- Volunteers
- 120 people
- Sponsor
- Hospital de Cruces
Breast Cancer, Sentinel Lymph Node
Axillary Management in Breast Cancer Patients With Needle Biopsy Proven Nodal Metastases After Neoadjuvant Chemotherapy
The aim of this study is to assess whether, omitting further axillary treatment (ALND and ART) for patients with early stage breast cancer and axillary nodal metastases on needle biopsy, who after NACT have no residual cancer in…
- Conditions
- Breast Cancer, Sentinel Lymph Node, Neoplasm, Breast
- Trial name
- ATNEC (NCT04109079)
- Testing
- Axillary lymph node dissection, Axillary radiotherapy, Breast or chest wall radiotherapy
- Where
- 98 sites in Ireland, United Kingdom
- Volunteers
- 1,900 people
- Sponsor
- University Hospitals of Derby and Burton NHS Foundation Trust
Breech Presentation, Vertex Presentation
Music and Sounds for ECV
This international study is looking to see if the addition of music and sound on the maternal abdomen encourages fetal position change from breech to vertex in near term women.
- Trial name
- RITMO (NCT01922453)
- Testing
- Music and Sound
- Where
- Israel
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Lung Neoplasms, Lymph Node Excision
Mediastinal Lymph Node Dissection Versus Spared Mediastinal Lymph Node Dissection in Stage I GGN NSCLC
Lung cancer is the leading cause of cancer related death worldwide. Lobectomy or sub-lobectomy with mediastinal lymph node dissection is the standard surgery. About 50% lung nodules are pure ground-glass or part-solid nodules.
- Trial name
- NCT04631770
- Testing
- Systemic mediastinal lymph node dissection, Spared mediastinal lymph node dissection
- Where
- China
- Volunteers
- 1,362 people
- Sponsor
- Tianjin Medical University Cancer Institute and Hospital
Breakthrough Pain
PIEB Compared With CEI on Breakthrough Pain in Nulliparous Women
The goal of this randomized controlled trial is to examine the impact of programmed intermittent bolus epidural analgesia technique on the incidence of breakthrough pain during labor in nulliparous women compared to continuous…
- Trial name
- NCT06494280
- Testing
- programmed intermittent Bolus epidural analgesia, continuous epidural infusion
- Where
- Israel
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Holy Family Hospital, Nazareth, Israel
Breast Cancer, Locally Advanced Breast Cancer
Sentinel Lymph Node Biopsy After Neoadjuvant Chemotherapy For Locally Advanced Breast Cancer
This study is being done to help the investigators determine how accurate the sentinel lymph node biopsy (SLNB) procedure is in identifying residual cancer cells after neoadjuvant chemotherapy in patients presenting with locally…
- Trial name
- NCT03255577
- Testing
- Sentinel Lymph Node Biopsy (SLNB)
- Where
- 8 sites in United States
- Volunteers
- 162 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Breakthrough Pain
Programmed Intermittent Epidural Bolus Compared With Continuous Infusion in Multiparous Women
The goal of this randomized controlled trial is to examine the impact of programmed intermittent bolus epidural analgesia technique on the incidence of breakthrough pain during labor in multiparous women compared to continuous…
- Trial name
- NCT06580327
- Testing
- programmed intermittent Bolus epidural analgesia, continuous epidural infusion
- Where
- Israel
- Volunteers
- 186 people, healthy volunteers welcome
- Sponsor
- Holy Family Hospital, Nazareth, Israel
Mucocutaneous Lymph Node Syndrome, Kawasaki Disease
A Randomized, Double Blind, Placebo Controlled Study of Etanercept in Children With Kawasaki Disease
The purpose of this study is to determine whether Etanercept (Enbrel) when used in conjunction with IVIG and aspirin, improves treatment response to IVIG in patients with Kawasaki Disease. Funding Source- FDA/OOPD
- Trial name
- NCT00841789
- Testing
- Etanercept
- Where
- 8 sites in United States, Canada
- Volunteers
- 205 people
- Sponsor
- Michael Portman
Lymph Node Excision
Systematic Sampling of Lymph Nodes vs. Lymphadenectomy According to Intraoperative Frozen Pathology for Pulmonary Invasive Adenocarcinoma With Ground-glass Opacity
The purpose of this study is to evaluate the impact of systematic sampling of lymph nodes vs. lymphadenectomy on outcome according to intraoperative frozen pathology for pulmonary invasive adenocarcinoma with ground-glass opacity…
- Trial name
- NCT03322826
- Testing
- systematic sampling of the lymph-node, lymphadenectomy
- Where
- China
- Volunteers
- 600 people
- Sponsor
- Shanghai Pulmonary Hospital, Shanghai, China
Breast Cancer, Cognitive/Functional Effects
Doxorubicin and Cyclophosphamide in Treating Older Women With Stage I, Stage II, or Stage III Breast Cancer That Has Been Removed By Surgery
RATIONALE: Drugs used in chemotherapy, such as doxorubicin and cyclophosphamide, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing.
- Conditions
- Breast Cancer, Cognitive/Functional Effects, Depression, Malnutrition
- Trial name
- NCT00424203
- Testing
- AC regimen, cyclophosphamide, doxorubicin hydrochloride
- Where
- 17 sites in France
- Volunteers
- 40 people
- Sponsor
- UNICANCER
Labor
Evaluation of Laborpro - a New Device for the Assessment of Progress of Labor
A clinical study was conducted to demonstrate the accuracy of the LaborPro System in measuring fetal head station (from the pelvic inlet), cervical dilatation, and fetal head position against manual/digital examination.
- Trial name
- NCT00827229
- Testing
- Labor Monitor
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Trig Medical Inc
Metastatic Head and Neck Squamous Cell Carcinoma, Metastatic Squamous Cell Carcinoma in Cervical Lymph Node
Fluciclovine F18 PET/CT in Identifying the Origin of Head and Neck Squamous Cell Carcinoma in Patients With Metastatic Cervical Nodal Disease
This early phase I trial studies how well fluciclovine F18 positron emission tomography (PET)/computed tomography (CT) works in identifying the origin of head and neck squamous cell carcinoma in patients with cancer that has…
- Trial name
- NCT03868020
- Testing
- Computed Tomography, Fluciclovine F18, Positron Emission Tomography
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- M.D. Anderson Cancer Center
Lymph Node Excision Biopsy
Prevalence of Epstein-Barr Virus Infection
This will be a cross sectional, pilot study to determine the burden of EBV related lymphomas in this population. Patient information including demographics and HIV status, history of HIV infection, HIV viral load and CD4 counts…
- Trial name
- NCT06444152
- Testing
- Sample analysis
- Where
- Botswana
- Volunteers
- 100 people
- Sponsor
- University of Pennsylvania
Twin Pregnancy With Antenatal Problem
External Cephalic Version (ECV) for Twins With Non-vertex Presenting Twin
In this study, women with a twin pregnancy with the presenting twin in a non-vertex(head) presenting twin undergo an external cephalic version.
- Trial name
- NCT05894785
- Testing
- External cephalic version
- Where
- Israel
- Volunteers
- 30 people
- Sponsor
- Shaare Zedek Medical Center