Clinical trials: Vestibular Disorder
Dizziness
Vestibular Rehabilitation and Dizziness in Geriatric Patients
The purpose of this study is to develop effective exercise intervention to reduce dizziness and fall risk in older adults with non-specific dizziness.
- Trial name
- NCT00275392
- Testing
- Vestibular rehabilitation
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- US Department of Veterans Affairs
Type 2 Diabetes
Examining the Effects of Neuromodulation on Glucose Metabolism in Type 2 Diabetes
This is an open-label, proof of concept study with a single active treatment arm designed to assess whether CVS-based stimulation has a beneficial effect on patients with type 2 diabetes.
- Trial name
- NCT02130401
- Testing
- TNM Device
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Scion NeuroStim
Neurofibromatosis 2, Vestibular Schwannoma
Trial of Selumetinib in Patients With Neurofibromatosis Type II Related Tumors
In this research study the researchers want to learn more about the effects (both good and bad) the study drug selumetinib has on participants with neurofibromatosis type II (NF2) related tumor.
- Conditions
- Neurofibromatosis 2, Vestibular Schwannoma, Meningioma, Ependymoma
- Trial name
- SEL-TH-1601 (NCT03095248)
- Testing
- Selumetinib
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
TBI, Attention Deficits
Galvanic Vestibular Stimulation and Motor Training in Traumatic Brain Injury Survivors
The overall goal of the proposed project is to perform a preliminary study to assess the potential effects of galvanic vestibular stimulation (GVS) on the outcomes of a cognitive test of attention and the outcomes of…
- Conditions
- TBI, Attention Deficits, Motor Impairments
- Trial name
- NCT01749800
- Testing
- GVS, Armeo Spring
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Spaulding Rehabilitation Hospital
Vestibular Neuronitis, Vestibular Neuronitis, Bilateral
Recovery of Visual Acuity in People With Vestibular Deficits
The purpose of this study is to determine whether exercises relieve the symptoms of dizziness and imbalance in people with vestibular deficits and improves the ability to see clearly during head movements.
- Conditions
- Vestibular Neuronitis, Vestibular Neuronitis, Bilateral, Vestibular Schwannoma
- Trial name
- NCT00411216
- Testing
- Control exercises, gaze stabilization exercises
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Emory University
Vestibular Diseases
Computerized Vestibular Rehabilitation
Disorders of vestibular function and balance are an important component of many conditions that commonly affect veterans, such as inner ear diseases, diabetes, and traumatic brain injury.
- Trial name
- NCT03589859
- Testing
- VOR Test, Computer Game, Nausea Scale
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Vestibular Schwannoma, NF2
Concentration and Activity of Lapatinib in Vestibular Schwannomas
Tumors can grow on the auditory nerves and can cause hearing loss. A common type of tumor that does this is a vestibular schwannoma (VS), or acoustic neuroma. These tumors are not cancerous. Most often, people have only one VS.
- Conditions
- Vestibular Schwannoma, NF2, Neurofibromatosis 2, Acoustic Neuroma
- Trial name
- NCT00863122
- Testing
- lapatinib
- Where
- 7 sites in United States
- Volunteers
- 26 people
- Sponsor
- Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Mild Traumatic Brain Injury, Balance; Distorted
Can Early Initiation of Rehabilitation With Wearable Sensor Technology Improve Outcomes in mTBI?
Every year 1.7 million people sustain a traumatic brain injury (TBI) in the United States and of these, 84 % are considered mild TBI (mTBI).
- Conditions
- Mild Traumatic Brain Injury, Balance; Distorted, Gait, Unsteady, Quality of Life
- Trial name
- NCT03479541
- Testing
- Timing of Rehabilitation, Biofeedback
- Where
- United States
- Volunteers
- 203 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Neurofibromatosis 2, Progressive Vestibular Schwannoma (VS)
Phase 2 Clinical Trial of Crizotinib for Children and Adults With Neurofibromatosis Type 2 and Progressive Vestibular Schwannomas
Subjects with Neurofibromatosis Type 2 (NF2) and progressive vestibular schwannoma (VS) will be treated with crizotinib administered orally.
- Trial name
- NF110 (NCT04283669)
- Testing
- Crizotinib
- Where
- 15 sites in United States
- Volunteers
- 12 people
- Sponsor
- University of Alabama at Birmingham
Meniere Disease
Phase 3 Study of OTO-104 in Subjects With Unilateral Meniere's Disease
The purpose of this study is to evaluate the effectiveness of OTO-104 for the treatment of Meniere's disease.
- Trial name
- NCT03664674
- Testing
- OTO-104
- Where
- 65 sites in United States, Belgium and 6 more
- Volunteers
- 148 people
- Sponsor
- Otonomy, Inc.
Dizziness
Vestibular Rehabilitation and Otolith Dysfunction
Recent studies suggest that otolith dysfunction is a common finding in individuals with a history of head trauma/blast exposure and/or noise-induced hearing loss.
- Trial name
- NCT02652442
- Testing
- Centrifugation Distance, Centrifugation Duration, Centrifugation Schedule
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Benign Paroxysmal Positional Vertigo
Treating Benign Paroxysmal Positional Vertigo (BPPV) in ED Patients
Benign Paroxysmal Positional Vertigo (BPPV) is a common complaint of emergency department patients. The importance of early diagnosis and treatment can lead to a much improved quality of life for patients afflicted by this…
- Trial name
- NCT00641797
- Testing
- Meclizine, Epley Maneuver, Lorazepam
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Lehigh Valley Hospital
Dizziness Chronic, Vertigo, Peripheral
Virtual Environments for Vestibular Rehabilitation
The specific aims of this pilot project are: Aim #1: Determine the extent to which sensory integration strategies differ between 28 individuals with unilateral vestibular hypofunction and 28 age-matched peers.
- Conditions
- Dizziness Chronic, Vertigo, Peripheral, Fall
- Trial name
- NCT04268745
- Testing
- Balance training, Traditional Vestibular Rehabilitation
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- New York University
Vertigo, Dizziness
Acute Video-oculography for Vertigo in Emergency Rooms for Rapid Triage (AVERT)
AVERT is a randomized controlled trial comparing video-oculography (VOG)-guided care to standard care to assess accuracy of diagnoses and initial management decisions for emergency department (ED) patients with a chief symptom of…
- Trial name
- AVERT (NCT02483429)
- Testing
- VRT Care
- Where
- 5 sites in United States
- Volunteers
- 130 people
- Sponsor
- Johns Hopkins University
Benign Paroxysmal Positional Vertigo
Treatment of Apogeotropic Horizontal Canal Benign Paroxysmal Positional Vertigo
To determine the short term therapeutic efficacies of Gufoni maneuver and mastoid oscillation in apogeotropic type of benign paroxysmal positional vertigo (BPPV) involving the horizontal semicircular canal (HC-BPPV), a…
- Trial name
- NCT02046980
- Testing
- Gufoni, Vibration
- Where
- South Korea
- Volunteers
- 209 people
- Sponsor
- Keimyung University Dongsan Medical Center
Meniere Disease, Ménière
SPI-1005 for the Treatment of Meniere's Disease
The study is a randomized, double-blind, placebo-controlled, multi-center clinical trial (RCT) with open-label extension study (OLE), of SPI-1005 in adult subjects with definite Meniere's disease with active symptoms within three…
- Trial name
- STOPMD-3 (NCT04677972)
- Testing
- Ebselen
- Where
- 12 sites in United States
- Volunteers
- 220 people
- Sponsor
- Sound Pharmaceuticals, Incorporated
HC-BPPV
Treatment of Apogeotropic Horizontal Canal Benign Paroxysmal Positional Vertigo
The purpose of this study was to compare the immediate efficacies of each treatment maneuvers in treatment of apogeotropic horizontal canal benign paroxysmal positional vertigo (HC-BPPV).
- Trial name
- BPPV-HC (NCT00810641)
- Testing
- Gufoni maneuver, Head-shaking maneuver
- Where
- 2 sites in South Korea
- Volunteers
- 157 people
- Sponsor
- Chonbuk National University
Neurofibromatosis Type 2, Progressive Vestibular Schwannomas
Phase 2 Study of Bevacizumab in Children and Young Adults With NF 2 and Progressive Vestibular Schwannomas
To determine the hearing response rate at 24 weeks after treatment with bevacizumab for symptomatic vestibular schwannomas (VS) in children and young adults with Neurofibromatosis Type 2 (NF 2).
- Trial name
- NCT01767792
- Testing
- Bevacizumab
- Where
- 12 sites in United States
- Volunteers
- 22 people
- Sponsor
- University of Alabama at Birmingham
Neurofibromatosis Type 2, Vestibular Schwannomas
Study of Axitinib in Patients With Neurofibromatosis Type 2 and Progressive Vestibular Schwannomas
The purpose of this study is to determine if the study drug, AXITINIB, has any effect on tumors found in patients with Neurofibromatosis Type 2 (NF2).
- Trial name
- NCT02129647
- Testing
- Axitinib
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- NYU Langone Health
Vestibular Disorder, Balance; Distorted
Individualized Vestibular Rehabilitation for Elderly With Self-Management and Gaming Elements
The aim of this study is to test whether when using the Vestibular Rehabilitation App older patients perform rehabilitation in a similar manner as when directly instructed by a clinician.
- Conditions
- Vestibular Disorder, Balance; Distorted, Vestibular Diseases
- Trial name
- NCT05436067
- Testing
- Vestibular rehabilitation app, Traditional Physical Therapy
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- CFD Research Corporation