Clinical trials: Vestibular Vertigo
Meniere Disease, Vertigo
Safety of APSLXR in Patients Presenting Vertigo of Vestibular Origin or Meniere's Disease
The purpose of this study is to evaluate the safety of APSLXR in participants with Meniere's disease or other Verigo of vestibular origin. Pharmacokinetics will also be evaluated in a small group.
- Conditions
- Meniere Disease, Vertigo, Vertigo Vestibular
- Trial name
- NCT04674735
- Testing
- APSLXR
- Sponsor
- Apsen Farmaceutica S.A.
Vertigo, Vestibular Diseases
China Dizziness and Vertigo Cohort Study （VERIDICAL STUDY）
The goal of this observational study is to characterize the clinical features, etiological distribution, and longitudinal outcomes of patients with dizziness and/or vertigo in real-world neurological and otolaryngological…
- Trial name
- dizziness (NCT07778901)
- Where
- China
- Volunteers
- 6,000 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Meniere's Disease, Benign Paroxysmal Positional Vertigo
CAVA: Dizziness Trial
Clinical investigation of a medical device (CAVA) for recording eye movements. Patients suffering from diagnosed dizziness conditions will wear the device for 23 hours a day, for 30 days.
- Conditions
- Meniere's Disease, Benign Paroxysmal Positional Vertigo, Recurrent Vestibulopathy, Vestibular Migraine
- Trial name
- CAVA (NCT04026516)
- Testing
- CAVA Device
- Where
- United Kingdom
- Volunteers
- 29 people
- Sponsor
- Norfolk and Norwich University Hospitals NHS Foundation Trust
Benign Paroxysmal Positional Vertigo (BPPV), Vestibular Hypofunction
Benign Paroxysmal Positional Vertigo With and Without Vestibular Hypofunction: Protocol for an Integrated Home-Based Exercise With Self-Managed Education Programme
The goal of this feasibility pilot randomised controlled trial is to determine whether a home-based exercise programme integrated with a self-managed education programme is feasible, acceptable, and safe for adults aged 60 years…
- Trial name
- NCT07747376
- Testing
- Home-based therapy, Standard Care (in control arm)
- Where
- Malaysia
- Volunteers
- 30 people
- Sponsor
- Muhammad Hizami bin Mustafa
Vertigo, Vestibular Disorder
Evaluation of Nystagmus Examination Using Wearable AR Glasses in Vertigo Patients
Background and Purpose: Vertigo is common in emergency and outpatient settings, yet standard oculomotor testing usually requires dedicated equipment and exam rooms.
- Conditions
- Vertigo, Vestibular Disorder, Nystagmus
- Trial name
- NCT07238387
- Testing
- Wearable Augmented Reality Glasses for Nystagmus Examination, Conventional Nystagmus Examination
- Where
- Taiwan
- Volunteers
- 200 people
- Sponsor
- Chang Gung Memorial Hospital
Migraine Associated Vertigo, Tinnitus
Comparing Migraine Preventive Therapies vs. Anti-CGRP Therapies for Tinnitus in Patients With Migraine (COMPACT-PM)
Many people with migraine also experience tinnitus - a persistent ringing, buzzing, or hissing in the ears - and research suggests these conditions share underlying biological mechanisms, including a protein called calcitonin…
- Conditions
- Migraine Associated Vertigo, Tinnitus, Migraine, Vestibular Migraine
- Trial name
- COMPACT-PM (NCT07655440)
- Testing
- Galcanezumab, Erenumab 70 mg, Eptinezumab
- Volunteers
- 120 people
- Sponsor
- Stanford University
Ménière's Disease, Vestibular Migraine
The CAVA Multicentre Dizziness Trial
The CAVA trial is a diagnostic accuracy multicentre device trial which aims to quantify the extent to which the CAVA system can differentiate three common inner-ear causes of dizziness: Ménière's disease, vestibular migraine and…
- Conditions
- Ménière's Disease, Vestibular Migraine, Benign Paroxysmal Positional Vertigo (BPPV)
- Trial name
- CAVA 2 (NCT05984901)
- Testing
- The continuous ambulatory vestibular assessment (CAVA) system
- Where
- United Kingdom
- Volunteers
- 4 people
- Sponsor
- Norfolk and Norwich University Hospitals NHS Foundation Trust
Acute Vestibular Syndrome, Vertigo
Diagnostic Work up and Management of Acute Onset Vertigo
Incidence: Dizziness or vertigo is a very prevalent complaint in the general population, and a common reason for seeking medical attention.
- Trial name
- NCT05062915
- Testing
- HINTS
- Where
- Denmark
- Volunteers
- 90 people
- Sponsor
- Esbjerg Hospital - University Hospital of Southern Denmark
Vestibular Dysfunction, Vestibular Diseases
Effects of Wiifit vs Conventional Vestibular Rehabilitation on Dizziness and Balance in Patients With Unilateral Peripheral Vestibular Dysfunction
Unilateral Peripheral Vestibular Dysfunction (UPVD) causes dizziness, imbalance, vertigo, and reduced quality of life. Conventional Vestibular Rehabilitation Therapy (cVRT) is effective, while WiiFit-based virtual reality…
- Conditions
- Vestibular Dysfunction, Vestibular Diseases, Vertigo, Dizziness
- Trial name
- NCT07587554
- Testing
- Vestibular Rehabilitation Therapy, Wiifit Vestibular Training
- Where
- Pakistan
- Volunteers
- 42 people
- Sponsor
- Foundation University Islamabad
Unilateral Peripheral Vestibular Hypofunction, Vestibular Disorders
Ai Chi-Based Rehabilitation for Peripheral Unilateral Vestibular Dysfunction
This study aims to evaluate the effects of an Ai Chi-based rehabilitation program on balance, dizziness severity, and quality of life in patients with unilateral peripheral vestibular hypofunction.
- Conditions
- Unilateral Peripheral Vestibular Hypofunction, Vestibular Disorders, Dizziness, Vertigo Benign Positional
- Trial name
- AICHI-VR (NCT07559162)
- Testing
- Ai Chi-based exercise program, Home-Based Vestibular Rehabilitation
- Volunteers
- 38 people
- Sponsor
- Gaziosmanpasa Research and Education Hospital
BPPV, Vestibular Diseases
Implementation of Evidence-Based Practice for Dizziness
The study evaluates the implementation of evidence-based practice for the management of patients with dizziness in the emergency department (ED) within a large integrated health care system.
- Conditions
- BPPV, Vestibular Diseases, Vertigo, Dizziness
- Trial name
- DIZZTINCT2 (NCT05634902)
- Testing
- CME Educational Intervention, Study Developed Educational Materials for Patients
- Where
- United States
- Volunteers
- 90,135 people
- Sponsor
- Ohio State University
Vertigo, Meniere's Disease
Genetic and Biohumoral Factors Involved in Menière's Disease and Their Correlation With Phenotypes
Aim of this work was to assess the role of polymorphisms belonging to genes involved in the regulation of ionic homeostasis in Caucasian patients with Ménière Disease (MD) and compare results with a cohort of patients affected by…
- Conditions
- Vertigo, Meniere's Disease, Vestibular Migraine
- Trial name
- Menière09 (NCT07518069)
- Testing
- a blood withdrawal will be obtained, blood withdrawal
- Where
- Italy
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- IRCCS San Raffaele
Vestibular Migraine
Exploring Mild Electrical Vestibular Stimulation as a New Treatment for Dizziness and Migraine Symptoms
Vestibular migraine is a common cause of repeated dizziness, imbalance, and headaches that affects about three percent of Canadians.
- Trial name
- NCT07368140
- Testing
- Electrical Vestibular Stimulation
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- University of Calgary
Vertigo, Dizziness
Acute Video-oculography for Vertigo in Emergency Rooms for Rapid Triage (AVERT)
AVERT is a randomized controlled trial comparing video-oculography (VOG)-guided care to standard care to assess accuracy of diagnoses and initial management decisions for emergency department (ED) patients with a chief symptom of…
- Trial name
- AVERT (NCT02483429)
- Testing
- VRT Care
- Where
- 5 sites in United States
- Volunteers
- 130 people
- Sponsor
- Johns Hopkins University
Benign Paroxysmal Positional Vertigo, BPPV
Treatment of Posterior Benign Paroxysmal Positional Vertigo With Mechanical Rotational Chair.
Comparison of treatment efficacy of Epley maneuver and 360 maneuver in a mechanical rotational chair (TRV chair) in patient with posterior benign paroxysmal positional vertigo (BPPV).
- Trial name
- NCT05834452
- Testing
- The Epley Maneuver, The 360 Degree Maneuver, Mechanical rotational chair
- Where
- Denmark
- Volunteers
- 128 people
- Sponsor
- Aalborg University Hospital
Vestibular Migraine, Dizziness
Chinese Real-world Study of Treatment of Vestibular Migraine
Vestibular migraine is a phenotype of migraine, characterized by more prominent vertigo symptoms compared to headache. Treatments for VM are mainly divided into two categories: acute treatment and preventive treatment.
- Conditions
- Vestibular Migraine, Dizziness, Vertigo
- Trial name
- NCT07203248
- Testing
- CGRP R Inhibitor; CGRP Inhibitor, none-CGRP
- Volunteers
- 2,000 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Headache Disorders, Primary, Headache Disorders, Secondary
China Headache and Vertigo Registry Study
In the Chinese Headache and Vertigo Registration Study, patients aged 4-99 years with headache (primary headache and secondary headache such as migraine and tension type headache), vertigo (vertigo diseases such as vestibular…
- Conditions
- Headache Disorders, Primary, Headache Disorders, Secondary, Migraine, Tension-Type Headache
- Trial name
- CHRS (NCT04939922)
- Where
- China
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Vertigo
Evaluation of the OtoBand in Subjects With Self-reported Vertigo to Reduce Severity of Vertigo in a Real-world Setting
This study seeks to gather data on the effect of a device, the OtoBand, in participants who have reported symptoms of vertigo, compared to the effect of using one of two sham devices.
- Trial name
- NCT04869020
- Testing
- Otoband
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Otolith Labs
Headache Disorders, Primary, Headache Disorders, Secondary
International Headache Registry Study
In the International Headache and Vertigo Registration Study, patients aged 4-99 years with headache (primary headache and secondary headache such as migraine and tension type headache), vertigo (vertigo diseases such as…
- Conditions
- Headache Disorders, Primary, Headache Disorders, Secondary, Migraine, Tension-Type Headache
- Trial name
- IHRS (NCT05418218)
- Where
- China
- Volunteers
- 200,000 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Colorectal Cancer, Oncologic Complications
The SaVe Project-Sarcopenia and Vertigo in Aging Patients With Colorectal Cancer
The goal of this clinical trial is to learn about the cause of dizziness and decline in walking ability in in older adults ≥65 years during chemotherapy treatment for colorectal cancer.
- Conditions
- Colorectal Cancer, Oncologic Complications, Comprehensive Geriatric Assessment, Vestibular Rehabilitation
- Trial name
- SaVe (NCT05710809)
- Testing
- Targeted specialized physical group-based exercise and Comprehensive Geriatric Assessement
- Where
- 2 sites in Denmark
- Volunteers
- 150 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet