Clinical trials: Vestibulodynia
Vestibulodynia
The Use of Acupuncture for the Treatment of Vulvar Vestibulitis
Randomized controlled trial designed to determine whether acupuncture is an effective treatment for vestibulitis.
- Trial name
- NCT02362763
- Testing
- Acupuncture
- Volunteers
- 42 people
- Sponsor
- Hadassah Medical Organization
Vulvodynia, Provoked Vestibulodynia
Biomodulation and Rehabilitation Interventions to tarGet Pelvic Health
This trial will provide evidence for the effective management of pain and pain-related domains among those who experience provoked vestibulodynia (PVD) using photobiomodulation (PBM) and multimodal physiotherapy (mPT) in a…
- Conditions
- Vulvodynia, Provoked Vestibulodynia, Dyspareunia
- Trial name
- BRIGHT (NCT06660212)
- Testing
- Photobiomodulation, Multimodal physiotherapy
- Where
- 2 sites in Canada
- Volunteers
- 240 people
- Sponsor
- University of Ottawa
Vulvodynia, Vulvar Vestibulitis
Acupuncture for Vulvodynia: A Pre-pilot Study
Vulvodynia is a women's pain condition. Women have pain in their vulva, the area in their genitals between the vagina and labia (lips of the vagina).
- Conditions
- Vulvodynia, Vulvar Vestibulitis, Dyspareunia, Pain
- Trial name
- NCT02704234
- Testing
- Active Acupuncture
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- University of Illinois Chicago
Lichen Sclerosus, Lichen Planus
Diagnostic Accuracy of "Three Rings Vulvoscopy" for Detection of Vulvar Dermatosis
The objective of the study was to determine sensitivity, specificity and diagnostic accuracy of "Three Rings Vulvoscopy" for detection of vulvar dermatosis using histopathology as the reference standard.
- Conditions
- Lichen Sclerosus, Lichen Planus, Lichen Simplex Chronicus, Vulvodynia
- Trial name
- DATRIV (NCT02732145)
- Testing
- "Three Rings Vulvoscopy" (TRIV), Histopathology
- Where
- Croatia
- Volunteers
- 328 people, healthy volunteers welcome
- Sponsor
- Ginekološka Poliklinika Dr. Vesna Harni
Provoked Vestibulodynia
Efficacy of Dry Needling in Reducing Pain During Sexual Intercourse
Chronic vulvar pain is a highly prevalent and debilitating condition affecting up to 16% of women. The most common subtype of vulvar pain, provoked vestibulodynia (PVD), is characterized by a sharp pain at the entry of the vagina…
- Trial name
- NCT07534345
- Testing
- Real dry needling
- Where
- 4 sites in Canada
- Volunteers
- 170 people
- Sponsor
- Université de Sherbrooke
Vestibulodynia
A Study of the Effects of Topical Capsaicin in the Treatment of Provoked Vestibulodynia
This study aims to assess the pain on contact in provoked vestibulodynia, measured with Visual Analogic Scale at week 0/week 2/week 6/week 12 after applying a patch of capsaicin.
- Trial name
- CAPSIVU (NCT02854670)
- Testing
- Capsaicin patch
- Where
- France
- Volunteers
- 10 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Provoked Vestibulodynia, Secondary Provoked Vestibulodynia
Topical Ketotifen 0.25% for Secondary Vestibulodynia
This is a Phase 2, multi-center, randomized, double-blind, placebo-controlled trial evaluating the safety and efficacy of topical ketotifen fumarate 0.25% cream in adult women with secondary provoked vestibulodynia (PVD).
- Conditions
- Provoked Vestibulodynia, Secondary Provoked Vestibulodynia, Vulvodynia, Vulvary Pain Disorders
- Trial name
- NCT07257029
- Testing
- Ketotifen Fumarate 0.25% Cream
- Where
- 3 sites in United States
- Volunteers
- 54 people
- Sponsor
- Center for Vulvovaginal Disorders
Vestibulodynia (VBD), Vulvodynia
Vestibulodynia At High Resolution: Omics Approach to Improve Diagnosis
According to recent nomenclature, vulvodynia is vulvar pain without a clear identifiable cause persisting for at least 3-months and distinguished from vulvar pain caused by a specific disorder (inflammatory, neoplastic…
- Trial name
- NCT06865963
- Testing
- vulvar biopsy and blood semples
- Where
- Italy
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Fondazione IRCCS Policlinico San Matteo di Pavia
Vulvar Diseases, Vulvar Pain
Efficacy Study of Topical Application of Nifedipine Cream to Treat Vulvar Vestibulitis
To evaluate the use of topical application of Nifedipine cream for the treatment of Provoked localized Vulvodynia (vestibulitis, vestibulodynia).
- Conditions
- Vulvar Diseases, Vulvar Pain, Vestibulitis, Vestibulodynia
- Trial name
- NCT00496184
- Testing
- Nifedipine cream topical application
- Where
- 2 sites in Israel
- Volunteers
- 30 people
- Sponsor
- Western Galilee Hospital-Nahariya
Vulvodynia
A Phase 2 Study to Evaluate the Efficacy and Safety of Pudafensine in Vulvodynia (Provoked Vestibulodynia)
The study (IP2015CS05) is a randomised, double-blind, placebo-controlled, 4-way cross-over trial studying the efficacy and safety of single dose administration of pudafensine in vulvodynia (provoked vestibulodynia) patients.
- Trial name
- NCT07391241
- Testing
- Pudafensine
- Where
- United Kingdom
- Volunteers
- 24 people
- Sponsor
- Initiator Pharma
Vestibulodynia
Long-Term Assessment of Quality of Life and Effectiveness of Onabotulinumtoxina Injections in Provoked Vestibulodynia
The study aims to assess and compare the pain in women suffering from provoked vestibulodynia, before treatment with botulinum injections, 3 months after treatment and 18 months after treatment.
- Trial name
- QUALVESTO (NCT02858375)
- Where
- France
- Volunteers
- 21 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Vestibulodynia, Vulvodynia
Savella in Treatment for Provoked Vestibulodynia
The primary aim of this study is to determine the efficacy of milnacipran in reducing pain in women with provoked vestibulodynia (PVD), a centrally mediated pain syndrome similar to fibromyalgia, that is characterized by severe…
- Trial name
- NCT01304589
- Testing
- Milnacipran
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- University of Tennessee
Vestibulodynia
Pilot Study to Assess the Efficacy of Cognitive-behavioral Couple Therapy for Provoked Vestibulodynia
The current pilot study aims to assess the feasibility and preliminary efficacy of a novel, 12-week targeted couple intervention (CBCT) for women with vulvodynia and their partners.
- Trial name
- NCT01582373
- Testing
- Cognitive-behavioral couple therapy
- Where
- Canada
- Volunteers
- 9 people
- Sponsor
- Université de Montréal
Vulvodynia, Provoked Vulvar Vestibulodynia
Physiotherapy Intervention for Provoked Vulvar Vestibulodynia
Hypothesis: 1. Specific physiotherapy interventions will decrease pain, improve pelvic floor motor control, increase self efficacy, improve sexual function and decrease pain catastrophizing behaviour in women with provoked vulvar…
- Trial name
- NCT01628679
- Testing
- Physical therapy treatment
- Where
- Canada
- Volunteers
- 125 people
- Sponsor
- University of British Columbia
Vulvodynia
Enoxaparin as Treatment for Vulvodynia
The investigators hypothesize that injections of Low molecular weight heparin (LMWH) [enoxaparin] will reduce pain in women with vulvodynia.
- Trial name
- NCT00874484
- Testing
- Clexane (enoxaparin)
- Where
- Israel
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Western Galilee Hospital-Nahariya
Vulvodynia, Vestibulodynia
Study of Emu Oil vs. Placebo for Vulvar Pain in Women.
The goal of this study is to determine if vulvar (external female genitalia) pain is decreased with emu oil over a similar placebo oil (no active ingredient) by using measurement devices, examinations, and questionnaires.
- Trial name
- NCT01295268
- Testing
- Emu Oil, Inert oil
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Corewell Health East
Provoked Vestibulodynia
Low Level Laser Therapy for the Treatment of Provoked Vestibulodynia
Provoked vestibulodynia, previously called vulvar vestibulitis syndrome, is clinically defined as chronic, unexplained, vulvar pain or discomfort confined to the vulvar vestibule in response to contact or pressure.
- Trial name
- LLLT (NCT01149031)
- Testing
- LOW LEVEL LASER SYSTEM
- Where
- Israel
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Provoked Vestibulodynia
Integrated Mindfulness-based Cognitive Behaviour Therapy Versus Cognitive Behaviour Therapy for Provoked Vestibulodynia
This randomized trial, nicknamed the COMFORT (Cognitive therapy or Mindfulness FOR Treatment of pvd) study, will compare the effects of an 8-session group Mindfulness-based Cognitive Therapy (MBCT) to an 8-session group Cognitive…
- Trial name
- COMFORT (NCT01704456)
- Testing
- Mindfulness-based Cognitive Therapy, Cognitive Behavioural Therapy
- Where
- 2 sites in Canada
- Volunteers
- 130 people
- Sponsor
- University of British Columbia
Vulvar Disease
Vulvar Vestibulitis Clinical Trial: Desipramine-Lidocaine
The Vulvar Vestibulitis Clinical Trial (VVCT) a randomized, placebo-controlled, double blinded clinical trial. We will study the clinical efficacy of four medical treatments for vulvar vestibulitis: topical lidocaine, oral…
- Trial name
- NCT00276068
- Where
- United States
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Vulvodynia, Vulvodynia, Generalized
Effect of Acupuncture on Patient Vulvodynia Outcomes
This study evaluates acupuncture for the treatment of vulvodynia; specifically if it reduces vulvar pain and pain with intercourse. It also examines how long the effect of acupuncture lasts in women with vulvodynia.
- Conditions
- Vulvodynia, Vulvodynia, Generalized, Vulvar Vestibulitis
- Trial name
- NCT03364127
- Testing
- Active Acupuncture
- Where
- United States
- Volunteers
- 89 people
- Sponsor
- University of Illinois Chicago