Clinical trials: Veterans
Major Depressive Disorder, Epilepsy
Neurobehavioral Therapy For Epilepsy And Major Depressive Disorder
The purpose of this study is to examine the feasibility and acceptability of an online group Neuro-behavioral Therapy (NBT) with text messaging intervention for Veterans with epilepsy and major depressive disorder (MDD).
- Trial name
- NCT06695767
- Testing
- Neurobehavioral therapy
- Where
- 2 sites in United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Insomnia, Posttraumatic Stress Disorder (PTSD)
Testing the Insomnia Coach Mobile App With Veterans With Insomnia and PTSD
The objective of this randomized controlled trial of the Insomnia Coach mobile app is to evaluate the potential effects of app use on reducing insomnia symptoms among Veterans with significant insomnia and PTSD symptoms.
- Trial name
- NCT07083869
- Testing
- Insomnia Coach, Sleep Well
- Volunteers
- 130 people
- Sponsor
- VA Palo Alto Health Care System
Stress Disorders, Post-Traumatic, Pain, Chronic
Mantram Repetition Versus Health Education for Veterans With PTSD and Chronic Pain
Approximately 450,000 Veterans Health Administration service users have both posttraumatic stress disorder (PTSD) and chronic pain (CP); treatments that efficiently target both PTSD and CP are limited, and new interventions…
- Trial name
- NCT07725588
- Testing
- Mantram Repetition Program for PTSD + Pain, Health Education while Living with Pain
- Where
- United States
- Volunteers
- 170 people
- Sponsor
- VA Office of Research and Development
Chronic Kidney Diseases
Effect of Empagliflozin on Podocyte Specific Proteins in African American Veterans With NDKD
Primary Objective: To study podocyte specific injury markers in African American Veterans with non-diabetic kidney disease (NDKD), on empagliflozin therapy.
- Trial name
- EMPA CKD (NCT06110130)
- Testing
- Empagliflozin 10 MG
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Washington D.C. Veterans Affairs Medical Center
Suicidal Ideation, Suicidal
Assessing the Utility of MMPI-2-RF-EX in Detecting Simulated Underreporting of Current Suicide Risk in Military Veterans
The aim of the current project are is examine the incremental predictive utility of the MMPI-2-RF-EX validity scales in detecting simulated underreporting of suicide risk on the MMPI-2-RF-EX and other self-report measures of…
- Trial name
- NCT04896151
- Testing
- Minnesota Multiphasic Personality Inventory -2- Restructured Form - Experimental
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Ohio State University
Gait, Unsteady, Postural Balance
Wii-Fit For Balance And Gait In Elderly Veterans
Falls are a major public health problem. They are the leading cause of injuries and injury-related deaths in those aged over 65 years. Balance and gait abnormalities are major reasons for falls in elderly.
- Trial name
- NCT02190045
- Testing
- Wii-Fit exercises, Cognitive remediation exercises
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Central Arkansas Veterans Healthcare System
Posttraumatic Stress Disorder
Trial of Mifepristone in Combat Veterans With Posttraumatic Stress Disorder
The investigators propose to conduct a randomized double-blind, parallel-group, placebo-controlled trial of mifepristone in veterans with military-related posttraumatic stress disorder (PTSD).
- Trial name
- NCT00833339
- Testing
- mifepristone
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- James J. Peters Veterans Affairs Medical Center
Total Knee Arthroplasty
Improving Rehabilitation for Veterans After Total Knee Arthroplasty Using Individualized Recovery Trajectories
This study will examine the impact of a new clinical decision support tool for rehabilitation after total knee arthroplasty (TKA).
- Trial name
- NCT05288803
- Testing
- Clinical decision support tool (CDS tool)
- Where
- 2 sites in United States
- Volunteers
- 200 people
- Sponsor
- VA Office of Research and Development
PTSD
Using Heart Rate Variability Biofeedback to Improve Attention and Memory in PTSD+ Combat Veterans
This study will test the effectiveness of Heart Rate Variability (HRV) Biofeedback as a therapeutic tool in the reduction of everyday memory problems routinely experienced by combat veterans with Posttraumatic Stress Disorder…
- Trial name
- HRVB (NCT00625105)
- Testing
- Biofeedback
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- William Jennings Bryan Dorn VA Medical Center
Heart Failure
The Re-Prosper HF Study
Heart failure with reduced ejection fraction (HFrEF) is a common cause for admission within the Veterans Affairs (VA) Health Care System.
- Trial name
- Re-Prosper HF (NCT04551222)
- Testing
- probenecid
- Where
- 5 sites in United States
- Volunteers
- 125 people
- Sponsor
- VA Office of Research and Development
Alcohol Use Disorder
AAT for Alcohol Use Disorder in Veterans
The proposed study will test a novel treatment for alcohol use disorders (AUD) to determine if it helps Veterans reduce their hazardous drinking and recover from alcohol-related functional impairments across social, occupational…
- Trial name
- NCT05372029
- Testing
- Approach Avoidance Training
- Where
- United States
- Volunteers
- 176 people
- Sponsor
- VA Office of Research and Development
Post Traumatic Stress Disorder, PTSD
The Family of Heroes: an Evaluation of an Online Educational Tool
The purpose of this study is to evaluate the effectiveness of a unique web based educational tool called "Family of Heroes," which is designed to educate families about Post Traumatic Stress Disorder (PTSD) and provide them with…
- Trial name
- NCT01554839
- Testing
- "Family of Heroes", Baseline and Follow up Surveys
- Where
- United States
- Volunteers
- 206 people
- Sponsor
- Department of Veterans Affairs, New Jersey
Post-traumatic Stress Disorders
Pilot of Acupuncture to Improve Quality of Life in Veterans With TBI and PTSD
The purpose of this study is to examine if acupuncture improves Post-Traumatic Stress Disorder symptoms among veterans who participated in Operations Enduring Freedom and Iraqi Freedom.
- Trial name
- NCT01060553
- Testing
- Acupuncture treatment
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- US Department of Veterans Affairs
Stress Disorders, Post-Traumatic
Using the Multiphase Optimization Strategy to Adapt Cognitive Processing Therapy
Cognitive Processing Therapy (CPT) consists of discrete therapeutic components that are delivered across 12 sessions, but most Veterans never reach session 12, and those who drop out receive only 4 sessions on average.
- Trial name
- CPT MOST (NCT05220137)
- Testing
- Modified A-B-C: Working with Events, Thoughts, and Feelings, Challenging Questions, Patterns of Problematic Thinking
- Where
- 3 sites in United States
- Volunteers
- 271 people
- Sponsor
- VA Office of Research and Development
Substance Use Disorders
Women Veterans' Substance Abuse Treatment
The purpose of this study is to examine the efficacy of a gender-focused addiction treatment model (A Woman's Path to Recovery) versus a non-gender focused addiction treatment model (12-Step Facilitation) in a sample of women…
- Trial name
- NCT00734903
- Testing
- A Woman's Path to Recovery, 12-Step Facilitation
- Where
- 2 sites in United States
- Volunteers
- 66 people
- Sponsor
- VA Office of Research and Development
Head and Neck Cancer, Alcohol Use, Unspecified
Alcohol Cessation Among Head and Neck Cancer Survivors
Head-and-neck cancers (HNC) account for 4 percent of cancer diagnoses in the United States and for more than 66,000 annual cancer diagnoses.
- Trial name
- NCT05570851
- Testing
- Alcohol Cessation Text Messages, Usual Care
- Where
- United States
- Volunteers
- 126 people
- Sponsor
- Northwell Health
Criminal Behavior, Criminal Recidivism
Dialectical Behavior Therapy for Justice-Involved Veterans
Dialectical Behavior Therapy for Justice-Involved Veterans (DBT-J) is a comprehensive, integrative program distinctively designed to address the range of mental health, substance use, case management, and legal needs of Veterans…
- Conditions
- Criminal Behavior, Criminal Recidivism, Psychosocial Functioning
- Trial name
- NCT05974553
- Testing
- Dialectical Behavior Therapy for Justice-Involved Veterans, Supportive Group Psychotherapy for Justice-Involved Veterans
- Where
- 2 sites in United States
- Volunteers
- 215 people
- Sponsor
- VA Office of Research and Development
Sleep Apnea
Behavioral Optimization to Overcome Obstructive Sleep Apnea Treatment Barriers
Previous studies have shown that programs encouraging the use of OSA treatments can help patients use these treatments more often, but the improvement is usually modest.
- Trial name
- BOOST (NCT07207473)
- Testing
- Behavioral strategy program X plus Y, Behavioral strategy program X
- Where
- 2 sites in United States
- Volunteers
- 128 people
- Sponsor
- VA Office of Research and Development
Nightmare
Treating Nightmares Among Domiciliary Patients
The purpose of the study is to assess the efficacy of a 2-session intervention to reduce nightmares among Veterans admitted VA mental health residential rehabilitation treatment programs.
- Trial name
- NCT04341987
- Testing
- brief Imagery Rehearsal Therapy, Treatment As Usual
- Volunteers
- healthy volunteers welcome
- Sponsor
- Canandaigua VA Medical Center
PTSD, Cognitive Impairment
(Neuro)Cognitive Remediation for Adults With OSIs
(Neuro)Cognitive remediation (CR) is an intervention for people experiencing cognitive impairments that interfere with their daily functioning.
- Conditions
- PTSD, Cognitive Impairment, Cognitive Dysfunction
- Trial name
- NCT06813378
- Testing
- (Neuro)Cognitive Remediation
- Volunteers
- 20 people
- Sponsor
- Nova Scotia Health Authority