Suicidal IdeationNCT04896151
Assessing the Utility of MMPI-2-RF-EX in Detecting Simulated Underreporting of Current Suicide Risk in Military Veterans
A study testing Minnesota Multiphasic Personality Inventory -2- Restructured Form - Experimental in people with Suicidal Ideation and Suicidal, run by Ohio State University at 1 site in United States.
Trial summary
The aim of the current project are is examine the incremental predictive utility of the MMPI-2-RF-EX validity scales in detecting simulated underreporting of suicide risk on the MMPI-2-RF-EX and other self-report measures of suicide risk in 150 military Veterans experiencing past-month death or suicidal ideation. Read more about this study
- Who is it for?
- Ages 18 years and older
- Conditions the study is for
- Suicidal Ideation, Suicidal
- What is being tested?
- Minnesota Multiphasic Personality Inventory -2- Restructured Form - Experimental
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 75 participants
- Where
- 1 siteUnited States
- Study dates
- 15 May 2021to 14 Feb 2023
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- 18 years of age or older
- US military veteran
- death or suicidal ideation/suicide attempt within the past month
Who cannot join
- non-Veteran status
- acute intoxication or active psychosis precluding provision of informed consent
- an inability to communicate and comprehend English
- residence outside the United States
- lack of past-month death/suicide ideation or attempt
- younger than 18 years of age
Trial locations and contacts
1 site in 1 country.
About this study
The aim of the current project are is examine the incremental predictive utility of the MMPI-2-RF-EX validity scales in detecting simulated underreporting of suicide risk on the MMPI-2-RF-EX and other self-report measures of suicide risk in 150 military Veterans experiencing past-month death or suicidal ideation.
- Conditions
- Suicidal Ideation, Suicidal
- Being tested
- Minnesota Multiphasic Personality Inventory -2- Restructured Form - Experimental
- Medical subject headings
- Suicidal Ideation
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Minnesota Multiphasic Personality Inventory -2- Restructured Form - ExperimentalDiagnostic test
Also called MMPI-2-RF-EX
The MMPI-2-RF-EX is a broadband, self-report measure of personality and psychopathology was developed for research purposes in order to develop the MMPI-3 (Ben-Porath \& Tellegen, 2020), which is comprised of a subset of MMPI-2-RF-EX items.
| Study group | Role | What they receive |
|---|---|---|
| Standard MMPI | Active comparator | Participants will be instructed to complete the MMPI-2-RF-EX and other measures under standard conditions (e.g., to not simulate underreporting of suicide risk). Receives: Diagnostic Test: Minnesota Multiphasic Personality Inventory -2- Restructured Form - Experimental |
| Simulation MMPI | Experimental | Participants will be instructed to conceal current suicide risk when completing the MMPI-2-RF-EX and other measures. Receives: Diagnostic Test: Minnesota Multiphasic Personality Inventory -2- Restructured Form - Experimental |
What is being measured
The primary outcome is the main question the study is designed to answer.
MMPI-2-RF-EX Suicidal/Death Ideation scale
The MMPI-2-RF-EX Suicidal/Death Ideation scale is a self-report measure of current suicide risk contained within the instrument. T scores range from 45 to 100, with higher scores indicative of greater suicide risk.
Measured: Baseline
Beck Scale for Suicide Ideation (BSS)
The BSS is a 21-item measure of past-week suicide ideation and desire for death. Responses to items are scored on a 3-point Likert scale (range of 0- 2). Scores range from 0 to 42, with higher scores indicating greater suicide risk.
Measured: Baseline
Secondary outcomes (1)
Suicide Cognitions Scale (SCS)
The SCS is an 18-item survey measuring suicide-related thoughts and beliefs, unclouding hopelessness, perceived burdensomeness, entrapment, and unbearability. Respondents rate their agreement with each statement on a 5-point Likert scale. Scores range from 18-90, with higher scores indicating more severe suicide risk.
Measured: Baseline
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted21 May 2021
- Study start15 May 2021
- Primary completion14 Feb 2023
- Study completion14 Feb 2023
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (1)Papers the sponsor has linked to this study.
- Other trials for Suicidal IdeationStudies of the same condition, open and under way.
- More trials run by Ohio State UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Diagnosis
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Enrolment
- 75 participants (actual)
Sponsor and investigators
- Lead sponsor
- Ohio State University
- Sponsor type
- University, hospital or other
- Collaborators
- University of Minnesota, Rutgers University
- Responsible party
- Principal investigator, Lauren Khazem, Ohio State University
- Investigators
- Lauren Khazem, PhD, Principal investigator, Ohio State University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT04896151
- Sponsor's protocol ID
- 2020B0414
- Status last verified
- Oct 2023
- First submitted
- 1 May 2021
- Last updated
- 5 Oct 2023
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Publications
Khazem LR, Keen MA, Rodriguez TR, Ingram PB, Hay JM, Long CM, Bryan CJ, Anestis JC. Detecting Simulated Underreporting on the Minnesota Multiphasic Personality Inventory-3 (MMPI-3) in Veterans With Past-Month Death/Suicide Ideation. Suicide Life Threat Behav. 2025 Apr;55(2):e13170. doi: 10.1111/sltb.13170.
PubMed 40135882
Study at a glance
From the registry record, last updated by the sponsor on 5 Oct 2023. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Assessing the Utility of MMPI-2-RF-EX in Detecting Simulated Underreporting of Current Suicide Risk in Military Veterans
- ClinicalTrials.gov ID
- NCT04896151
- Acronym / sponsor ID
- 2020B0414
- Conditions
- Suicidal Ideation, Suicidal
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 75 participants (actual)
- Lead sponsor
- Ohio State UniversityUniversity, hospital or other
- Collaborators
- University of Minnesota, Rutgers University
- Study start
- 15 May 2021 (actual)
- Primary completion
- 14 Feb 2023 (actual)
- Study completion
- 14 Feb 2023 (actual)
- First posted
- 21 May 2021 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The aim of the current project are is examine the incremental predictive utility of the MMPI-2-RF-EX validity scales in detecting simulated underreporting of suicide risk on the MMPI-2-RF-EX and other self-report measures of suicide risk in 150 military Veterans experiencing past-month death or suicidal ideation.
Study design
- Primary purpose
- Diagnosis
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Standard MMPI | Active comparator | Diagnostic Test: Minnesota Multiphasic Personality Inventory -2- Restructured Form - ExperimentalParticipants will be instructed to complete the MMPI-2-RF-EX and other measures under standard conditions (e.g., to not simulate underreporting of suicide risk). |
| Simulation MMPI | Experimental | Diagnostic Test: Minnesota Multiphasic Personality Inventory -2- Restructured Form - ExperimentalParticipants will be instructed to conceal current suicide risk when completing the MMPI-2-RF-EX and other measures. |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (3 listed)
- 18 years of age or older
- US military veteran
- death or suicidal ideation/suicide attempt within the past month
Key exclusion criteria (6 listed)
- non-Veteran status
- acute intoxication or active psychosis precluding provision of informed consent
- an inability to communicate and comprehend English
- residence outside the United States
- lack of past-month death/suicide ideation or attempt
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Minnesota Multiphasic Personality Inventory -2- Restructured Form - ExperimentalAlso: MMPI-2-RF-EXThe MMPI-2-RF-EX is a broadband, self-report measure of personality and psychopathology was developed for research purposes in order to develop the MMPI-3 (Ben-Porath \& Tellegen, 2020), which is comprised of a subset of MMPI-2-RF-EX items. | Diagnostic test | Simulation MMPI, Standard MMPI |
Primary outcome
MMPI-2-RF-EX Suicidal/Death Ideation scale
Time frame: Baseline
The MMPI-2-RF-EX Suicidal/Death Ideation scale is a self-report measure of current suicide risk contained within the instrument. T scores range from 45 to 100, with higher scores indicative of greater suicide risk.
Beck Scale for Suicide Ideation (BSS)
Time frame: Baseline
The BSS is a 21-item measure of past-week suicide ideation and desire for death. Responses to items are scored on a 3-point Likert scale (range of 0- 2). Scores range from 0 to 42, with higher scores indicating greater suicide risk.
1 secondary outcome
Suicide Cognitions Scale (SCS)
Time frame: Baseline
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 5 Oct 2023.
- Derived from this study: PubMed 40135882Khazem LR, Keen MA, Rodriguez TR, Ingram PB, Hay JM, Long CM, Bryan CJ, Anestis JC. Detecting Simulated Underreporting on the Minnesota Multiphasic Personality Inventory-3 (MMPI-3) in Veterans With Past-Month Death/Suicide Ideation. Suicide Life Threat Behav. 2025 Apr;55(2):e13170. doi: 10.1111/sltb.13170.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Lauren Khazem, PhD principal investigator
Ohio State University
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Minnesota Multiphasic Personality Inventory -2- Restructured Form - Experimental in people with Suicidal Ideation and Suicidal, run by Ohio State University at 1 site in United States.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 3 inclusion and 6 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 5 Oct 2023. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in United States. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
MMPI-2-RF-EX Suicidal/Death Ideation scale (time frame: Baseline). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT04896151, which also lists 1 linked publication.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 5 Oct 2023.