Clinical trials: Video Capsule Endoscopy
Colonic Diseases
PillCam™ Colon Capsule Endoscopy (PCCE) in the Visualization of the Colon
To see if PillCam COLON will demonstrate diagnostic yield >80% in detecting significant colonic pathologies when compared to colonoscopy in the target population.
- Trial name
- MA-53 (NCT00604162)
- Testing
- PillCam COLON, Standard colonoscopy
- Where
- 7 sites in France, Germany and 3 more
- Volunteers
- 332 people
- Sponsor
- Medtronic - MITG
Colorectal Lesions
Evaluation of Capsule Endoscopy With PillCam® Colon 2 in Visualization of the Colon
This pilot, multi center study will establish the effectiveness of Given PillCam® Platform with the PillCam® Colon 2 Capsule as demonstrated by the identification of subjects with polyps, compared to standard colonoscopy.
- Trial name
- NCT01269372
- Testing
- PillCam Colon 2, Colonoscopy
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Medtronic - MITG
Crohn Disease
Clinical Study Comparing PillCam® Crohn's Capsule Endoscopy to Ileocolonoscopy (IC) Plus MRE for Detection of Active CD in the Small Bowel and Colon in Subjects With Known CD and Mucosal Disease.
This study will evaluate the efficacy of capsule endoscopy (CE) versus ileocolonoscopy (IC) plus MRE for detection of active Crohn's disease (CD) in the small bowel in subjects with known CD and mucosal disease.
- Trial name
- BLINK (NCT03241368)
- Testing
- Capsule Endoscopy
- Where
- 26 sites in United States, Austria and 1 more
- Volunteers
- 187 people
- Sponsor
- Medtronic - MITG
Intestinal Abnormalities
Diagnosis of Intestinal Motility by Image Analysis Using Capsule Endoscopy
Conventional intestinal manometry is the current gold standard for the evaluation of intestinal motility, and identifies patterns of intestinal dysmotility.
- Trial name
- NCT01085513
- Testing
- PillCam SB2
- Where
- 6 sites in United States, Belgium and 3 more
- Volunteers
- 143 people, healthy volunteers welcome
- Sponsor
- Medtronic - MITG
Gastrointestinal Bleeding
Risk Factors for Rebleeding in Patients With Obscure Gastrointestinal Bleeding
The investigators investigated the rebleeding rate the risk factors for rebleeding after long-term follow-up (≥12 months) in patients who underwent capsule endoscopy for obscure gastrointestinal bleeding.
- Trial name
- NCT01821326
- Volunteers
- 339 people
- Sponsor
- Shanghai Jiao Tong University School of Medicine
Capsule Endoscopy
The Second-Generation MCCG for Upper Gastrointestinal Tract.
The aim of this study is to evaluate the clinical application of the second-generation MCCG with higher image resolution and frame rate for upper gastrointestinal tract compared with the first-generation.
- Trial name
- NCT03977935
- Testing
- the second-generation MCCG
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Changhai Hospital
Colorectal Cancer Screening
Colon Capsule Endoscopy (CCE) Versus Computed Tomographic Colonography (CTC) in the Identification of Colonic Polyps in a Screening Population.
The primary objective of this multicenter, prospective, randomized study is to assess the diagnostic yield of Colon Capsule Endoscopy (CCE) versus Computed Tomographic Colonography (CTC) in a screening population.
- Trial name
- TOPAZ (NCT02754661)
- Testing
- COLON Capsule endoscopy, Computed Tomographic Colonography
- Where
- 13 sites in United States
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Medtronic - MITG
Gastrointestinal Disease, Infectious Disease
Feasibility of Non-contact Magnetically-controlled Capsule Endoscopy During COVID-19 Pandemic
In December 2019, an outbreak of pneumonia associated with a novel coronavirus named as severe acute respiratory syndrome coronavirus 2 (SARSCoV-2) was reported in Wuhan city, China, and spread exponentially throughout China and…
- Conditions
- Gastrointestinal Disease, Infectious Disease, Capsule Endoscopy
- Trial name
- NCT04389333
- Testing
- non-contact magnetically-controlled capsule endoscopy
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Changhai Hospital
Known Crohn Disease Subjects
Monitoring Disease Activity Using Video Capsule Endoscopy (VCE) in Crohn's Disease (CD) Subjects
This study is designed to evaluate the performance of VCE in the assessment of mucosal inflammation 6 months after the first VCE procedure
- Trial name
- NCT01942720
- Testing
- Capsule endoscopy and Ileocolonoscopy tests
- Where
- 15 sites in United States
- Volunteers
- 74 people
- Sponsor
- Medtronic - MITG
Esophageal Varices
Wired Magnetically Assisted Capsule Endoscopy and Esophageal Varices
The goal of this clinical trial is to compare the safeness and effectiveness of traditional esophagogastroduodenoscope (EGD) and wired magnetically assisted capsule endoscopy (MACE) in the diagnosis of esophageal varices in…
- Trial name
- NCT06017102
- Testing
- wired magnetic assisted capsule endoscopy, esophagogastroduodenoscopy
- Where
- Taiwan
- Volunteers
- 50 people
- Sponsor
- National Taiwan University Hospital
Outpatients
Detachable String Magnetically Controlled Capsule Endoscopy for Completely Viewing of Esophagus and Stomach
The purpose of the study is to determine the safety and feasibility of the new technique,detachable string magnetically controlled capsule endoscopy(DS-MCE)for evaluating gastric and esophagus diseases.
- Trial name
- NCT03457909
- Testing
- DS-MCE
- Where
- China
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Changhai Hospital
Gastroparesis, Dyspepsia
Magnetically Controlled Capsule Endoscopy Feasibility Study in Gastric Motility
This is a feasibility study to assess the utility of magnetically controlled capsule endoscopy in the evaluation of gastroparesis and functional dyspepsia
- Trial name
- NCT05004012
- Testing
- Magnetically Controlled Capsule Endoscopy
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Gastrointestinal Lesions, Signs and Symptoms, Digestive
Small Bowel Capsule Endoscopy Findings in Patients Receiving Cellcept®
The purpose of this study is to learn more about symptoms and gastrointestinal lesions associated with taking myfortic® by switching patients to a delayed release formulation that is developed to alleviate GI symptoms.
- Trial name
- NCT00652834
- Testing
- Small bowel capsule endoscopy (SBCE), myfortic
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- University of California, Los Angeles
IBD
Capsule Endoscopy in Inflammatory Bowel Disease (IBD) in Children
Most of the studies evaluating the roles of MRE and WCE conducted in pediatric patients have been retrospective with the main goal of making a diagnosis in patients with suspected IBD.
- Trial name
- CE (NCT02182947)
- Testing
- Capsule endoscopy
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Children's Mercy Hospital Kansas City
Inflammatory Bowel Disease
Randomized, Placebo-controlled Trial of Lubiprostone as a Preparation for Capsule Endoscopy
This investigation is designed to compare lubiprostone and placebo for cleansing and propulsion in preparation for capsule endoscopy.
- Trial name
- NCT00746395
- Testing
- Lubiprostone
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of South Alabama
Pill Capsule Endoscopy Completion Rates
Study of Metoclopramide in Small Bowel Capsule Endoscopy
Patients undergoing small bowel capsule endoscopy will be randomized into 3 study groups to either receive 5 mg of metoclopramide, 10 mg of metoclopramide, or a placebo 30 minutes prior to swallowing the Pill Cam.
- Trial name
- NCT01630109
- Testing
- Metoclopramide
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Ascension Health
Colorectal Cancer Screening
Optimization of the Bowel Preparation Regimen for the PillCam® COLON 2 Capsule Endoscopy Procedure
This study is designed to determine the optimal bowel preparation regimen for PillCam® COLON 2 Capsule Endoscopy System (CCE) procedures in average risk patients.
- Trial name
- NCT02481219
- Testing
- PillCam® COLON 2 procedure-CONTROL, Senna tablets, PEG
- Where
- 6 sites in United States
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Medtronic - MITG
Gastrointestinal Hemorrhage
Video Capsule Endoscopy Versus Colonoscopy in Patients With Melena and Negative Upper Endoscopy
Acute gastrointestinal bleeding is a common medical problem. When patients with gastrointestinal bleeding present with melena (dark, tarry stool) the blood loss is usually originating in the upper gastrointestinal tract…
- Trial name
- NCT02609100
- Testing
- Video Capsule Endoscopy, Colonoscopy, 1.0 X 2.5 cm 'pill' containing a camera
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Washington University School of Medicine
Gastro-oesophageal Reflux Disease
Physical Activity and Gastrointestinal Investigations
This is an observational study, which aims to compare the outcomes of ambulatory gastrointestinal investigations with physical activity using accelerometry.
- Trial name
- NCT01507298
- Where
- United Kingdom
- Volunteers
- 21 people
- Sponsor
- Imperial College London
Abdominal Pain, Gastritis
MAGNET (Magnetically Controlled Capsule for Assessment of Gastric Mucosa in Symptomatic Patients)
This pilot and feasibility study will be first US study to determine if a magnetically controlled capsule (MCC) can effectively visualize the anatomy of the stomach like a more traditional upper endoscopy (EGD).
- Conditions
- Abdominal Pain, Gastritis, Gastric Ulcer, Gastric Cancer
- Trial name
- NCT04724291
- Testing
- MAGNET
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- George Washington University